Homo sapiens (human): 84649 Help Entry 84649             CDS       T01001                                  Symbol DGAT2, ARAT, GS1999FULL, HMFN1045 Name (RefSeq) diacylglycerol O-acyltransferase 2   KO K11160   diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.75] Organism hsa  Homo sapiens (human) Pathway hsa00561   Glycerolipid metabolism hsa01100   Metabolic pathways hsa04975   Fat digestion and absorption Module hsa_M00089   Triacylglycerol biosynthesis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00561 Glycerolipid metabolism     84649 (DGAT2)  09150 Organismal Systems   09154 Digestive system    04975 Fat digestion and absorption     84649 (DGAT2) Enzymes [BR:hsa01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.20  diacylglycerol O-acyltransferase      84649 (DGAT2)     2.3.1.75  long-chain-alcohol O-fatty-acyltransferase      84649 (DGAT2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DAGAT Acyltransferase Motif Other DBs NCBI-GeneID:  84649 NCBI-ProteinID:  NP_115953 OMIM:  606983 HGNC:  16940 Ensembl:  ENSG00000062282 UniProt:  Q96PD7 LinkDB All DBs Position 11:75768778..75801534 Genome browser AA seq 388 aa AA seqDB search MKTLIAAYSGVLRGERQAEADRSQRSHGGPALSREGSGRWGTGSSILSALQDLFSVTWLN RSKVEKQLQVISVLQWVLSFLVLGVACSAILMYIFCTDCWLIAVLYFTWLVFDWNTPKKG GRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNFSTEATE VSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVSRDTIDYLLSKNGSGNAIIIVVGG AAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPIYSFGENEVYKQVIFEEGSWGRWVQ KKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITIPKLEHPTQQDIDLYHT MYMEALVKLFDKHKTKFGLPETEVLEVN NT seq 1167 nt NT seq  +upstreamnt  +downstreamnt atgaagaccctcatagccgcctactccggggtcctgcgcggcgagcgtcaggccgaggct gaccggagccagcgctctcacggaggacctgcgctgtcgcgcgaggggtctgggagatgg ggcactggatccagcatcctctccgccctccaggacctcttctctgtcacctggctcaat aggtccaaggtggaaaagcagctacaggtcatctcagtgctccagtgggtcctgtccttc cttgtactgggagtggcctgcagtgccatcctcatgtacatattctgcactgattgctgg ctcatcgctgtgctctacttcacttggctggtgtttgactggaacacacccaagaaaggt ggcaggaggtcacagtgggtccgaaactgggctgtgtggcgctactttcgagactacttt cccatccagctggtgaagacacacaacctgctgaccaccaggaactatatctttggatac cacccccatggtatcatgggcctgggtgccttctgcaacttcagcacagaggccacagaa gtgagcaagaagttcccaggcatacggccttacctggctacactggcaggcaacttccga atgcctgtgttgagggagtacctgatgtctggaggtatctgccctgtcagccgggacacc atagactatttgctttcaaagaatgggagtggcaatgctatcatcatcgtggtcgggggt gcggctgagtctctgagctccatgcctggcaagaatgcagtcaccctgcggaaccgcaag ggctttgtgaaactggccctgcgtcatggagctgacctggttcccatctactcctttgga gagaatgaagtgtacaagcaggtgatcttcgaggagggctcctggggccgatgggtccag aagaagttccagaaatacattggtttcgccccatgcatcttccatggtcgaggcctcttc tcctccgacacctgggggctggtgccctactccaagcccatcaccactgttgtgggagag cccatcaccatccccaagctggagcacccaacccagcaagacatcgacctgtaccacacc atgtacatggaggccctggtgaagctcttcgacaagcacaagaccaagttcggcctcccg gagactgaggtcctggaggtgaactga

Homo sapiens (human): 8694 Help Entry 8694              CDS       T01001                                  Symbol DGAT1, ARAT, ARGP1, DGAT, DIAR7 Name (RefSeq) diacylglycerol O-acyltransferase 1   KO K11155   diacylglycerol O-acyltransferase 1 [EC:2.3.1.20 2.3.1.75 2.3.1.76] Organism hsa  Homo sapiens (human) Pathway hsa00561   Glycerolipid metabolism hsa00830   Retinol metabolism hsa01100   Metabolic pathways hsa04975   Fat digestion and absorption Module hsa_M00089   Triacylglycerol biosynthesis Disease H01174   Congenital diarrhea Drug target Pradigastat (DG01846):  D10657 D10664 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00561 Glycerolipid metabolism     8694 (DGAT1)   09108 Metabolism of cofactors and vitamins    00830 Retinol metabolism     8694 (DGAT1)  09150 Organismal Systems   09154 Digestive system    04975 Fat digestion and absorption     8694 (DGAT1) Enzymes [BR:hsa01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.20  diacylglycerol O-acyltransferase      8694 (DGAT1)     2.3.1.75  long-chain-alcohol O-fatty-acyltransferase      8694 (DGAT1)     2.3.1.76  retinol O-fatty-acyltransferase      8694 (DGAT1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MBOAT Motif Other DBs NCBI-GeneID:  8694 NCBI-ProteinID:  NP_036211 OMIM:  604900 HGNC:  2843 Ensembl:  ENSG00000185000 UniProt:  O75907 Structure PDBPDBj LinkDB All DBs Position 8:complement(144314584..144326852) Genome browser AA seq 488 aa AA seqDB search MGDRGSSRRRRTGSRPSSHGGGGPAAAEEEVRDAAAGPDVGAAGDAPAPAPNKDGDAGVG SGHWELRCHRLQDSLFSSDSGFSNYRGILNWCVVMLILSNARLFLENLIKYGILVDPIQV VSLFLKDPYSWPAPCLVIAANVFAVAAFQVEKRLAVGALTEQAGLLLHVANLATILCFPA AVVLLVESITPVGSLLALMAHTILFLKLFSYRDVNSWCRRARAKAASAGKKASSAAAPHT VSYPDNLTYRDLYYFLFAPTLCYELNFPRSPRIRKRFLLRRILEMLFFTQLQVGLIQQWM VPTIQNSMKPFKDMDYSRIIERLLKLAVPNHLIWLIFFYWLFHSCLNAVAELMQFGDREF YRDWWNSESVTYFWQNWNIPVHKWCIRHFYKPMLRRGSSKWMARTGVFLASAFFHEYLVS VPLRMFRLWAFTGMMAQIPLAWFVGRFFQGNYGNAAVWLSLIIGQPIAVLMYVHDYYVLN YEAPAAEA NT seq 1467 nt NT seq  +upstreamnt  +downstreamnt atgggcgaccgcggcagctcccggcgccggaggacagggtcgcggccctcgagccacggc ggcggcgggcctgcggcggcggaagaggaggtgcgggacgccgctgcgggccccgacgtg ggagccgcgggggacgcgccagccccggcccccaacaaggacggagacgccggcgtgggc agcggccactgggagctgaggtgccatcgcctgcaggattctttattcagctctgacagt ggcttcagcaactaccgtggcatcctgaactggtgtgtggtgatgctgatcttgagcaat gcccggttatttctggagaacctcatcaagtatggcatcctggtggaccccatccaggtg gtttctctgttcctgaaggatccctatagctggcccgccccatgcctggttattgcggcc aatgtctttgctgtggctgcattccaggttgagaagcgcctggcggtgggtgccctgacg gagcaggcgggactgctgctgcacgtggccaacctggccaccattctgtgtttcccagcg gctgtggtcttactggttgagtctatcactccagtgggctccctgctggcgctgatggcg cacaccatcctcttcctcaagctcttctcctaccgcgacgtcaactcatggtgccgcagg gccagggccaaggctgcctctgcagggaagaaggccagcagtgctgctgccccgcacacc gtgagctacccggacaatctgacctaccgcgatctctactacttcctcttcgcccccacc ttgtgctacgagctcaactttccccgctctccccgcatccggaagcgctttctgctgcga cggatccttgagatgctgttcttcacccagctccaggtggggctgatccagcagtggatg gtccccaccatccagaactccatgaagcccttcaaggacatggactactcacgcatcatc gagcgcctcctgaagctggcggtccccaatcacctcatctggctcatcttcttctactgg ctcttccactcctgcctgaatgccgtggctgagctcatgcagtttggagaccgggagttc taccgggactggtggaactccgagtctgtcacctacttctggcagaactggaacatccct gtgcacaagtggtgcatcagacacttctacaagcccatgcttcgacggggcagcagcaag tggatggccaggacaggggtgttcctggcctcggccttcttccacgagtacctggtgagc gtccctctgcgaatgttccgcctctgggcgttcacgggcatgatggctcagatcccactg gcctggttcgtgggccgctttttccagggcaactatggcaacgcagctgtgtggctgtcg ctcatcatcggacagccaatagccgtcctcatgtacgtccacgactactacgtgctcaac tatgaggccccagcggcagaggcctga

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