Homo sapiens (human): 11315
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Entry
11315 CDS
T01001
Symbol
PARK7, DJ-1, DJ1, GATD2, HEL-S-67p
Name
(RefSeq) Parkinsonism associated deglycase
KO
K05687
protein DJ-1 [EC:
3.5.1.124
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
Network
nt06463
Parkinson disease
nt06466
Pathways of neurodegeneration
Element
N01051
Mutation-inactivated DJ1 to intrinsic apoptotic pathway
N01057
Mutation-inactivated DJ1 to FAS-JNK signaling patwhay
N01058
Mutation-inactivated DJ1 to to p53-mediated transcription
N01059
Mutation-inactivated DJ1 to KEAP1-NRF2 signaling pathway
Disease
H00057
Parkinson disease
H01600
Parkinsonian syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
11315 (PARK7)
05022 Pathways of neurodegeneration - multiple diseases
11315 (PARK7)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
11315 (PARK7)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
11315 (PARK7)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.124 protein deglycase
11315 (PARK7)
Peptidases and inhibitors [BR:
hsa01002
]
Cysteine peptidases
Family C56: PfpI endopeptidase family
11315 (PARK7)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
11315 (PARK7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DJ-1_PfpI
ThiJ_like
GATase_3
LPD16
Motif
Other DBs
NCBI-GeneID:
11315
NCBI-ProteinID:
NP_001116849
OMIM:
602533
HGNC:
16369
Ensembl:
ENSG00000116288
UniProt:
Q99497
V9HWC2
Structure
PDB
LinkDB
All DBs
Position
1:7961711..7985505
Genome browser
AA seq
189 aa
AA seq
DB search
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLED
AKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFG
SKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQ
VKAPLVLKD
NT seq
570 nt
NT seq
+upstream
nt +downstream
nt
atggcttccaaaagagctctggtcatcctggctaaaggagcagaggaaatggagacggtc
atccctgtagatgtcatgaggcgagctgggattaaggtcaccgttgcaggcctggctgga
aaagacccagtacagtgtagccgtgatgtggtcatttgtcctgatgccagccttgaagat
gcaaaaaaagagggaccatatgatgtggtggttctaccaggaggtaatctgggcgcacag
aatttatctgagtctgctgctgtgaaggagatactgaaggagcaggaaaaccggaagggc
ctgatagccgccatctgtgcaggtcctactgctctgttggctcatgaaataggttttgga
agtaaagttacaacacaccctcttgctaaagacaaaatgatgaatggaggtcattacacc
tactctgagaatcgtgtggaaaaagacggcctgattcttacaagccgggggcctgggacc
agcttcgagtttgcgcttgcaattgttgaagccctgaatggcaaggaggtggcggctcaa
gtgaaggctccacttgttcttaaagactag
DBGET
integrated database retrieval system
