Homo sapiens (human): 30061
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Entry
30061 CDS
T01001
Symbol
SLC40A1, FPN, FPN1, HFE4, IREG1, MST079, MSTP079, MTP1, SLC11A3
Name
(RefSeq) solute carrier family 40 member 1
KO
K14685
solute carrier family 40 (iron-regulated transporter), member 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04216
Ferroptosis
hsa04978
Mineral absorption
Network
nt06525
Ferroptosis
Element
N01591
Fe2+ Ferroportin transport
Disease
H00211
Hemochromatosis
Drug target
Vamifeport (
DG03215
):
D12289
D12290
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
30061 (SLC40A1)
09150 Organismal Systems
09154 Digestive system
04978 Mineral absorption
30061 (SLC40A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
30061 (SLC40A1)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC40: Basolateral iron transporter
30061 (SLC40A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FPN1
DUF347
Motif
Other DBs
NCBI-GeneID:
30061
NCBI-ProteinID:
NP_055400
OMIM:
604653
HGNC:
10909
Ensembl:
ENSG00000138449
Pharos:
Q9NP59
(Tchem)
UniProt:
Q9NP59
Structure
PDB
PDBj
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All DBs
Position
2:complement(189560590..189580786)
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AA seq
571 aa
AA seq
DB search
MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLL
TAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHEL
LTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRI
DQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK
EEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV
SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAF
TWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITP
TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLL
QENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFR
FAQNTLGNKLFACGPDAKEVRKENQANTSVV
NT seq
1716 nt
NT seq
+upstream
nt +downstream
nt
atgaccagggcgggagatcacaaccgccagagaggatgctgtggatccttggccgactac
ctgacctctgcaaaattccttctctaccttggtcattctctctctacttggggagatcgg
atgtggcactttgcggtgtctgtgtttctggtagagctctatggaaacagcctccttttg
acagcagtctacgggctggtggtggcagggtctgttctggtcctgggagccatcatcggt
gactgggtggacaagaatgctagacttaaagtggcccagacctcgctggtggtacagaat
gtttcagtcatcctgtgtggaatcatcctgatgatggttttcttacataaacatgagctt
ctgaccatgtaccatggatgggttctcacttcctgctatatcctgatcatcactattgca
aatattgcaaatttggccagtactgctactgcaatcacaatccaaagggattggattgtt
gttgttgcaggagaagacagaagcaaactagcaaatatgaatgccacaatacgaaggatt
gaccagttaaccaacatcttagcccccatggctgttggccagattatgacatttggctcc
ccagtcatcggctgtggctttatttcgggatggaacttggtatccatgtgcgtggagtac
gttctgctctggaaggtttaccagaaaaccccagctctagctgtgaaagctggtcttaaa
gaagaggaaactgaattgaaacagctgaatttacacaaagatactgagccaaaacccctg
gagggaactcatctaatgggtgtgaaagactctaacatccatgagcttgaacatgagcaa
gagcctacttgtgcctcccagatggctgagcccttccgtaccttccgagatggatgggtc
tcctactacaaccagcctgtgtttctggctggcatgggtcttgctttcctttatatgact
gtcctgggctttgactgcatcaccacagggtacgcctacactcagggactgagtggttcc
atcctcagtattttgatgggagcatcagctataactggaataatgggaactgtagctttt
acttggctacgtcgaaaatgtggtttggttcggacaggtctgatctcaggattggcacag
ctttcctgtttgatcttgtgtgtgatctctgtattcatgcctggaagccccctggacttg
tccgtttctccttttgaagatatccgatcaaggttcattcaaggagagtcaattacacct
accaagatacctgaaattacaactgaaatatacatgtctaatgggtctaattctgctaat
attgtcccggagacaagtcctgaatctgtgcccataatctctgtcagtctgctgtttgca
ggcgtcattgctgctagaatcggtctttggtcctttgatttaactgtgacacagttgctg
caagaaaatgtaattgaatctgaaagaggcattataaatggtgtacagaactccatgaac
tatcttcttgatcttctgcatttcatcatggtcatcctggctccaaatcctgaagctttt
ggcttgctcgtattgatttcagtctcctttgtggcaatgggccacattatgtatttccga
tttgcccaaaatactctgggaaacaagctctttgcttgcggtcctgatgcaaaagaagtt
aggaaggaaaatcaagcaaatacatctgttgtttga
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