VARIANT: 4744v1
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Entry
4744v1 Variant
Name
NEFH mutation
Type
Loss of function
Gene
NEFH
neurofilament heavy chain [KO:
K04574
]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
mutations
OmimVar:
162230
Network
nt06541
Cytoskeleton in neurons
Disease
H00058
Amyotrophic lateral sclerosis (ALS)
Reference
PMID:
9931323
Authors
Al-Chalabi A, Andersen PM, Nilsson P, Chioza B, Andersson JL, Russ C, Shaw CE, Powell JF, Leigh PN
Title
Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis.
Journal
Hum Mol Genet 8:157-64 (1999)
DOI:
10.1093/hmg/8.2.157
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