KEGG   Hydrogenobacter thermophilus: HTH_0024
Entry
HTH_0024          CDS       T01167                                 
Symbol
nrdA
Name
(GenBank) ribonucleotide reductase alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
hth  Hydrogenobacter thermophilus
Pathway
hth00230  Purine metabolism
hth00240  Pyrimidine metabolism
hth01100  Metabolic pathways
hth01232  Nucleotide metabolism
Module
hth_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
hth_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:hth00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    HTH_0024 (nrdA)
   00240 Pyrimidine metabolism
    HTH_0024 (nrdA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hth03400]
    HTH_0024 (nrdA)
Enzymes [BR:hth01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     HTH_0024 (nrdA)
DNA repair and recombination proteins [BR:hth03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    HTH_0024 (nrdA)
SSDB
Motif
Pfam: Ribonuc_red_lgC Ribonuc_red_lgN ATP-cone RNR-II_ins_dom
Other DBs
NCBI-ProteinID: BAI68491
UniProt: D3DF89
LinkDB
Position
24076..26379
AA seq 767 aa
MYVTKRSGVGEPMDISKIRIVIDFACRGLRVDPLELEADAQIQFREGISTKEIQQLLIRT
AAEKVSPENPDWQYVAARLLLYDLYKDVGHIRGYKVKDKINGRYKPYNPESFYNLVKNYA
EKGIYGEYLLREYSKEDFQALASYIKPDRDLLFNYTGIKVLYDRYLVRDEEGNVIELPQE
MYMLISMSLALPEKKEERIKWVKTFYDLMSKHEVSLATPTLMNARRPHTQLSSCFVLTVD
DDLYDIFDNVQKAGQISKFAGGLGIYLGKVRATGSPIRKFKGASSGVLPVVKILNDVMVY
VDQLGMRKGSASITLDIWHKDVMDFLEVKTNVGDERKKAHDIHPAISIPDIFMKRLKNRE
KWTLLDPYYCKNVKDGKNLEDFYGEEFEELYQRLERELPPNAKKEVDAFELWKRLLTVVF
ETGEPYIFFRDTANRLNPNKHCGVVYSSNLCHEIVQNMSASQHIEDSLDPQTGEIVHRKK
SGDVVVCNLGSINLGKVYTKEDMERVVPLLVRMLDNVISINYYAIKEAEYTNRRYRAIGI
GVSNYHYCLVKNAIQWESEEHLKFANALFERIAYYAIKGSMELAKERGRYPLFEGSDWSK
GVFFGRDAEENQRMSEKNGNNLNWIELAEEVKTYGLRNAYLLALMPTGSTSLIIGATPSV
DPIFAKFYKEENMSGILPQVPPEIDRYFWHYKSAYSIDQEWIIRAASERQKWIDQAQSLN
LFIDPEHVDGPTLSKLYELSWELGLKTVYYCRSKSLTEIEECESCSS
NT seq 2304 nt   +upstreamnt  +downstreamnt
atgtatgtaacaaagagaagcggtgttggagagcctatggacatatccaagatacgcata
gttatagactttgcctgcagaggattgagggttgacccccttgaactggaagctgatgcc
cagatacagttcagagagggcatatccacaaaggaaatacaacaactccttataagaacc
gctgcggaaaaggtttctccggaaaacccagactggcagtatgtagcagcaaggcttttg
ctttacgacctttacaaagatgtgggacacataaggggatacaaggtaaaggacaagata
aacggcaggtataagccttacaatcccgaaagcttttataaccttgtaaaaaattacgct
gagaaaggcatatatggagagtatctgctcagggagtattccaaagaggactttcaagct
ttggcaagctacataaagccagacagggacttactctttaactacacaggcataaaagtc
ctgtatgataggtatctggtgagggatgaagaggggaatgttatagagcttccacaagag
atgtacatgctaattagcatgagcttagccctgccagagaaaaaggaggaaaggataaag
tgggttaaaactttttacgaccttatgtctaagcatgaggtgtctttggctacaccgacg
cttatgaacgcaagaagaccccacacccagctctcatcctgctttgtactgaccgtggat
gatgacctttatgacatatttgacaacgtgcagaaggccggacagatatccaaatttgcg
ggagggctgggcatatacttgggcaaggtcagagcaacaggctcacccataaggaagttt
aaaggtgcatcttcgggagttctgccagtggtcaaaatattaaacgatgttatggtttat
gtggatcagctgggcatgaggaaaggttctgcatccataacccttgacatatggcacaag
gatgttatggactttctggaagtaaagaccaatgtgggagacgagaggaaaaaagctcac
gatattcaccccgccatatccataccagacatctttatgaagaggctcaaaaacagagaa
aagtggacacttcttgacccatactactgcaaaaacgtaaaagatggcaaaaatctggaa
gacttctacggagaggagtttgaggagctataccagagactggaaagagagcttccgccc
aacgctaaaaaagaggtggatgcctttgaactctggaagagactgctaactgtcgtattt
gaaactggagagccttacatctttttcagagacactgccaacaggctaaatcccaacaaa
cactgcggagtggtttacagctccaacctctgccatgagatagtccagaacatgtctgca
agccagcacatagaagactctttagaccctcaaacgggagaaatagtccacaggaagaag
tccggagatgtggtggtttgcaacttaggctctataaacttaggcaaagtttatacaaag
gaagatatggaaagagttgtgccactgctagtcaggatgctggacaatgtcatatctata
aactactatgccataaaggaagcagagtacaccaacagacgctacagggcaatagggata
ggtgtaagcaactaccactactgtctggtgaagaacgctatccaatgggagtcagaagag
cacctcaagtttgcaaacgcactctttgaaaggatagcttactatgctataaaaggctct
atggagctagcaaaggagagaggcagataccctctgtttgaaggttctgactggagcaag
ggagtattctttggaagagatgcagaagaaaaccaaaggatgtctgagaaaaatggcaac
aacctaaactggatagaactggcagaggaggtaaaaacatatgggctcagaaacgcatac
cttcttgcactcatgccaactggttctacctccctcataattggtgcaactccttccgtg
gaccccatatttgccaagttttacaaggaggagaacatgtcaggcatacttcctcaggta
ccccctgagatagacaggtacttctggcactataagagtgcctacagcatagaccaggag
tggattataagagccgcatctgaaaggcaaaagtggatagaccaggctcagtctctgaat
ctctttatagatccagaacatgttgatggacctacactttcaaagctctacgagctttcc
tgggagctgggactgaaaaccgtttactactgcagaagtaaatctctaacagagatagaa
gagtgtgaaagctgttcaagttaa

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