Kluyveromyces marxianus: KLMA_50283
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Entry
KLMA_50283 CDS
T05269
Symbol
ADE6
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
kmx
Kluyveromyces marxianus
Pathway
kmx00230
Purine metabolism
kmx01100
Metabolic pathways
kmx01110
Biosynthesis of secondary metabolites
Module
kmx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
kmx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
KLMA_50283 (ADE6)
Enzymes [BR:
kmx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
KLMA_50283 (ADE6)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-GeneID:
34716889
NCBI-ProteinID:
XP_022676747
UniProt:
W0TBC7
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Position
5:605070..609119
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AA seq
1349 aa
AA seq
DB search
MSVSILAGPQALSQFRIDSLVKGLESYCNSTGFIKEVRSCYVHYVDLKAELSKEDQELVS
VLLTYDTALDLSDDFNKKLVESVTSNAAASLGDDTYLIRITPRRGTISPWSSKATNIAHV
CNLEDKVARIERGLALLIKCNAGFPLMERLNDVSLKNVYDRMTQELFLDQPPVVTELFNH
DAPKPLVHVPLVSQTSKSPSETLAKANVELGLALDQGEIDYLIRAFVETMKRDPTDVELF
MFAQVNSEHCRHKIFNADWTIDGLQKQLTLFKMIRNTHQITPDFTVSAYSDNAAVLDTEN
DSYYYAPEFKTKKWTATKERVPMLIKVETHNHPTAVSPFPGAATGSGGEIRDEGATGRGS
KSKCGLSGFSVSDLLIPGKEMPWELNVGKPNHIASALDIMIEAPLGSAAFNNEFGRPCIN
GYFRTLTTKVVNADGKEEIRGFHKPIMIAGGFGAVRPQFALKNKPITPGSSLIVLGGQSM
LIGLGGGAASSIASGEGSADLDFASVQRGNPEMERRCQQVIDACVSLNENNPIQSIHDVG
AGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSQQDLATFE
SICKRERAPFAVVGHATAEQKLIVEDSLLKSTPIDLDMSILFGKPPKMAREAITEPLQLP
QPNLSQIPSMEDAIDRVLHLPAVGSKSFLITIGDRTVTGLIDRDQFVGPWQVPVADVGVT
ATALGDEIRSTGEAMAMGERPSAALVSAAASAKLSVAESLLNVFAADVKSLKHIKLSANW
MSPASHKGEGAKLYEAVQAIGMDLCPDLGVSIPVGKDSMSMKMKWDDKEVTAPLSLNITA
FAPVKNTSKTWTPLLSKESGETILVLVDLAALQEQRSLGASALLQVYNQIGNTVPTVHDN
KVLKGFLESILELHETDLVLSYHDRSDGGLLVTLLEMAFAARCGLDVIVDSSKDGNAFVP
LFNEELGAVFQIKESSLTQFQSILAKHGVSHQYVSVVGKPNFVSNMVTITEKSGAVLYEN
TRAELQKSWSSTSYEMQKLRDNPKTTIQEFSAIADDKDPGLHYALTFNPADDLQIGTQLA
NVRPKVAILREQGVNGQMEMAWCFQQAGFDAIDVTMTDLIEGTFNLSEFTGIAACGGFSY
GDVLGAGAGWAKSVLYHEGVRKQFVNFFQEREDTFAFGACNGCQFLSRLKSIIPGCEDWP
SFERNMSEQYEARVCMVEIVQDQTRQTESVFFNGMVGSKLPIAVAHGEGKATFESQEQLD
KFESQGLTGVRYIDNYGNVTEKFPFNPNGSPNGISGITSPNGRVLAMMPHPERVSRLEAN
SWYPQGKFEEWEGYGPWIRLFRSARKWVG
NT seq
4050 nt
NT seq
+upstream
nt +downstream
nt
atgtccgttagtatcttagcgggtccccaggctctttctcaatttagaatcgattcttta
gtaaaaggcttggaatcatattgcaacagtactggctttatcaaagaagttcgttcctgt
tacgttcattatgttgatttgaaagctgagctttcgaaggaagaccaggagcttgtttct
gtgttgctaacgtacgatacagctttggatttgagcgatgacttcaacaagaagttggtt
gaatctgtgaccagcaatgccgcagcctccttaggtgatgatacctacttgattagaatt
acccctcgtcgtggtaccatttctccatggtcatctaaggctacaaacattgctcatgtc
tgtaacttggaagacaaggttgcgagaatcgaaagaggtttagctctattgataaagtgc
aatgctggtttcccattgatggagcgcttaaatgacgtttccttgaagaacgtgtacgat
agaatgacccaagagttgttcttggaccaacctcctgtagttaccgaattgttcaaccac
gatgcaccaaagcctttggttcacgttccattagttagccaaacaagtaagtctccttct
gaaactttagccaaggctaacgttgaattaggtcttgctttggaccaaggtgaaattgac
tacttgattcgtgcatttgtggaaacaatgaagagagatccaacagatgtcgagttgttc
atgttcgctcaagtcaactcggagcattgccgtcataagatcttcaacgctgattggact
attgatggtctacaaaagcaattgactttgttcaagatgatcagaaacactcatcaaatt
actccagacttcaccgtgtctgcttattcagataacgctgccgttcttgacaccgagaat
gactcctattactatgcacctgaattcaaaaccaagaagtggactgccaccaaggaaaga
gttcctatgttgatcaaagtggaaacccacaaccatcctactgcggtctcacctttccca
ggtgcagccactggttctggtggtgaaattagagatgaaggtgccaccggtagaggttcc
aagagtaaatgtggtctttctggtttctctgtttctgacttgctaattccaggtaaagaa
atgccttgggaattgaacgttggtaagccaaaccacatcgcatctgcacttgacatcatg
attgaagccccattgggttctgcagccttcaacaatgaatttggtagaccttgtatcaac
ggttactttagaactttgacaactaaggttgttaacgctgacggcaaggaggaaatcaga
ggtttccataagccaatcatgatcgctggtggtttcggtgctgttagacctcaatttgcc
ttgaagaacaaaccaattacaccaggctccagtttaatcgtcttgggtggtcaatctatg
ttgattggtctaggtggtggtgctgcatcgtccattgcgtctggtgaaggttccgctgac
ttagactttgcttctgttcaaagaggtaacccagagatggaacgtcgttgccaacaagtc
attgatgcctgtgtctctttgaatgaaaataacccaatccaatctatccacgatgtcggt
gcaggtggtttgtctaatgccttgcctgaattggttcacgataacgacttgggtgccaag
tttgacatcagaaaggtgctatctctagaaccaggtatgtcccctatggaaatttggtgt
aatgaatctcaagaaagatacgttcttggtgtctcccaacaggatcttgccacatttgaa
agtatttgtaagagagaaagagcaccatttgctgtcgttggtcatgccactgctgaacaa
aaactaattgtcgaagattctctattgaaaagcaccccaattgacctagatatgtctatt
ctatttggtaaaccaccaaaaatggccagagaagctataacagagcctttacaattacct
caaccaaacctctctcaaattccttctatggaagatgctatcgatcgtgttttacattta
ccagccgttggctcgaaatcgtttttgatcacaatcggtgatagaactgttactgggttg
attgatagggaccaatttgtgggtccatggcaagtacctgtcgctgatgttggtgttaca
gctactgcacttggtgatgagatccgttcgactggtgaggccatggcaatgggtgaaaga
ccatctgctgctctggtatctgccgctgcatctgcaaaactctctgtggcagaatctctt
ctaaacgtatttgctgcagatgttaaatcattgaagcatatcaagctatctgctaactgg
atgtctccagcatctcataaaggtgaaggtgctaagctatacgaagctgttcaagccatt
ggtatggatctatgtcctgatttaggtgtatccattcctgttggaaaagattctatgtct
atgaagatgaaatgggatgacaaagaagtcactgccccactatctttgaatatcactgct
tttgcccctgttaaaaacacctccaagacctggactccattgttgagcaaagagagtggt
gagactatccttgttcttgtcgatctagctgctctacaagaacaaagatccctaggcgcc
tccgcattgctgcaagtgtataatcaaattggtaacactgtaccaactgttcatgacaac
aaggttctaaaaggtttcttagaatctattttggaacttcatgaaactgacttggttcta
tcttaccacgacagatctgatggtggtttgttagtgaccttgttagaaatggcctttgcc
gctagatgtggtttggatgtcattgttgactccagcaaggacggtaacgcatttgttcca
ttattcaatgaagaattaggtgctgtcttccaaatcaaagaatcttctctaacacaattc
caaagcattcttgccaaacatggtgtttcccaccaatatgtgtctgttgtcggtaagcct
aactttgtttcaaatatggttactattaccgagaaatctggtgcagtgctttacgagaac
actagggctgaattacagaagagctggtcatctacatcttatgaaatgcaaaagttaaga
gacaatccaaagactacaattcaagaattctctgctattgctgatgacaaggacccaggt
ttgcactacgcgttgactttcaacccagctgatgacttgcaaattggcactcagttggca
aacgttagaccaaaggttgctattctaagagaacaaggtgttaatggtcaaatggaaatg
gcatggtgtttccaacaagctggatttgatgccattgacgttactatgacagatttgatc
gaaggtacctttaatctatcggagttcactggtattgctgcatgtggtggtttctcctat
ggtgatgttttgggtgctggtgctggttgggctaagtctgttctttaccacgaaggtgtt
cgtaaacaatttgttaacttcttccaagaaagagaagatacatttgcctttggtgcctgt
aatggttgtcaattcctcagtagattaaaatctatcattccaggatgcgaagactggcca
agctttgaaagaaacatgagtgaacaatacgaggctcgtgtttgtatggttgaaattgtc
caagaccaaacccgtcaaaccgagtctgtattcttcaacggtatggttggctccaagcta
ccgattgctgttgctcacggagaaggtaaggctacttttgaaagccaagaacaacttgat
aaattcgaaagccaaggcttaaccggtgtgagatacattgacaattacggtaacgtaaca
gagaagttcccattcaatccaaacggttctccaaatggtatttcaggtatcacttctcca
aacggtagagttctagcgatgatgccccatccggaaagagtatctagactagaagctaac
tcgtggtatccacaaggcaagttcgaggaatgggaaggttacggcccatggatcagattg
ttcagatctgctagaaagtgggtgggttag
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