KEGG   PATHWAY: ko03264
Entry
ko03264                     Pathway                                
Name
Virion - Flavivirus and Alphavirus
Class
Genetic Information Processing; Information processing in viruses
Pathway map
ko03264  Virion - Flavivirus and Alphavirus
ko03264

Other DBs
PDB: 5IRE 5LBS 2XFB 3J2W 3N42 5VU2 5H23
Orthology
K05116  TYRO3, RSE; TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]
K06563  CLEC4L_M, DC-SIGN, CD209, CD299; C-type lectin domain family 4 member L/M
K17080  PHB1; prohibitin 1
K19288  p130; Alphavirus structral polyprotein
K20413  HAVCR1, CD365; hepatitis A virus cellular receptor 1
K24402  MXRA8; matrix remodeling-associated protein 8
K24570  POLY; Flavivirus structral polyprotein
K25003  E; Flavivirus envelope protein E
K25126  E2; Alphavirus spike glycoprotein E2
K25300  gp1; Alphavirus polyprotein P1234
K25326  NS4B; Flavivirus non-structural protein 4B
K25327  NS1; Flavivirus non-structural protein 1
K25328  NS3; Flavivirus serine protease NS3 catalytic subunit
K25329  NS2B; Flavivirus serine protease subunit NS2B
K25330  NS4A; Flavivirus non-structural protein 4A
K25331  NS2A; Flavivirus non-structural protein 2A
K25332  NS5; Flavivirus RNA-directed RNA polymerase NS5
K25804  E1; Alphavirus spike glycoprotein E1
K25923  nsP2; Alphavirus protease nsP2
K25929  C; Alphavirus capsid protein
K25999  M; Flavivirus small envelope protein M
K26000  C; Flavivirus capsid protein C
K26140  nsP4; Alphavirus RNA-directed RNA polymerase nsP4
Compound
C00607  Chondroitin sulfate
C00925  Heparan sulfate
Reference
PMID:27033547
  Authors
Sirohi D, Chen Z, Sun L, Klose T, Pierson TC, Rossmann MG, Kuhn RJ
  Title
The 3.8 A resolution cryo-EM structure of Zika virus.
  Journal
Science 352:467-70 (2016)
DOI:10.1126/science.aaf5316
Reference
PMID:32060358
  Authors
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
  Title
Capsid protein structure in Zika virus reveals the flavivirus assembly process.
  Journal
Nat Commun 11:895 (2020)
DOI:10.1038/s41467-020-14647-9
Reference
PMID:21124458
  Authors
Voss JE, Vaney MC, Duquerroy S, Vonrhein C, Girard-Blanc C, Crublet E, Thompson A, Bricogne G, Rey FA
  Title
Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography.
  Journal
Nature 468:709-12 (2010)
DOI:10.1038/nature09555
Reference
PMID:23577234
  Authors
Sun S, Xiang Y, Akahata W, Holdaway H, Pal P, Zhang X, Diamond MS, Nabel GJ, Rossmann MG
  Title
Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
  Journal
Elife 2:e00435 (2013)
DOI:10.7554/eLife.00435
Reference
PMID:29203665
  Authors
Yap ML, Klose T, Urakami A, Hasan SS, Akahata W, Rossmann MG
  Title
Structural studies of Chikungunya virus maturation.
  Journal
Proc Natl Acad Sci U S A 114:13703-13707 (2017)
DOI:10.1073/pnas.1713166114
Reference
PMID:31080061
  Authors
Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH
  Title
Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
  Journal
Cell 177:1725-1737.e16 (2019)
DOI:10.1016/j.cell.2019.04.006
Reference
PMID:29306785
  Authors
Sharma R, Kesari P, Kumar P, Tomar S
  Title
Structure-function insights into chikungunya virus capsid protein: Small molecules targeting capsid hydrophobic pocket.
  Journal
Virology 515:223-234 (2018)
DOI:10.1016/j.virol.2017.12.020

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