Inoue N, Hess KD, Moreadith RW, Richardson LL, Handel MA, Watson ML, Zinn AR

New gene family defined by MORC, a nuclear protein required for mouse spermatogenesis.

Hum Mol Genet 8:1201-7 (1999)
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[hsa:27136]

Zanni G, Nardella M, Barresi S, Bellacchio E, Niceta M, Ciolfi A, Pro S, D'Arrigo S, Tartaglia M, Bertini E

De novo p.T362R mutation in MORC2 causes early onset cerebellar ataxia, axonal polyneuropathy and nocturnal hypoventilation.

Brain 140:e34 (2017)
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[hsa:22880]

Andrews FH, Tong Q, Sullivan KD, Cornett EM, Zhang Y, Ali M, Ahn J, Pandey A, Guo AH, Strahl BD, Costello JC, Espinosa JM, Rothbart SB, Kutateladze TG

Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.

Cell Rep 16:3195-3207 (2016)
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[hsa:23515]

Liggins AP, Cooper CD, Lawrie CH, Brown PJ, Collins GP, Hatton CS, Pulford K, Banham AH

MORC4, a novel member of the MORC family, is highly expressed in a subset of diffuse large B-cell lymphomas.

Br J Haematol 138:479-86 (2007)
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[hsa:79710]

Tchasovnikarova IA, Timms RT, Douse CH, Roberts RC, Dougan G, Kingston RE, Modis Y, Lehner PJ

Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2.

Nat Genet 49:1035-1044 (2017)
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Moissiard G, Cokus SJ, Cary J, Feng S, Billi AC, Stroud H, Husmann D, Zhan Y, Lajoie BR, McCord RP, Hale CJ, Feng W, Michaels SD, Frand AR, Pellegrini M, Dekker J, Kim JK, Jacobsen SE

MORC family ATPases required for heterochromatin condensation and gene silencing.

Science 336:1448-51 (2012)
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[ath:AT4G36290 AT1G19100]