Kosakonia radicincitans: A3780_25320
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Entry
A3780_25320 CDS
T04579
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
krd
Kosakonia radicincitans
Pathway
krd00260
Glycine, serine and threonine metabolism
krd00261
Monobactam biosynthesis
krd00270
Cysteine and methionine metabolism
krd00300
Lysine biosynthesis
krd01100
Metabolic pathways
krd01110
Biosynthesis of secondary metabolites
krd01120
Microbial metabolism in diverse environments
krd01230
Biosynthesis of amino acids
Module
krd_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
krd_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
krd_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
krd00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
A3780_25320 (metL)
00270 Cysteine and methionine metabolism
A3780_25320 (metL)
00300 Lysine biosynthesis
A3780_25320 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
A3780_25320 (metL)
Enzymes [BR:
krd01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
A3780_25320 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
A3780_25320 (metL)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
APG20721
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Position
5452199..5454631
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AA seq
810 aa
AA seq
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MSVIAQAGTKARQLHKFGGSSLADVKCYLRVAGIMAEYSQPGDMMVVSAAGSTTNQLINW
LKLSQTDRLSAHQVQQSLRRYQSDLIGGLLPADVADGLTSEFIHDLEHLAALLDGGITDA
VYAEVVGHGEIWSARLMAAVLNQQGLDAAWLDARDFLRAERSAQPQVNEGASYPLLQQKL
AQHPGKRIVVTGFISRNEAGETVLLGRNGSDYSATQIGALGDVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSNIDLQLRCSYNPDQGSTRIER
VLASGTGARIVTSHDDVCLIEFIVPAGQDFKLAQKEIDLLLKRAQARPLAVGAHADRNLL
QLCYTSEVVDSVFKLLDEAGLPGELRLRQGLALVAMVGAGVCRNPLHSHRFWQQLKGQPV
EFIWQSDEGISLVAVLRVGPTESLIQGLHQSLFRAEKRIGLMLFGKGNIGSRWLELFSRE
QSALSARTGFEFVLAGVVDSRRSLLNYDGLDASRALAFFNDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASEQLAGQYLDFASHGFHVISANKLAGASTTNNYRQIHDAFEKTGRHWLYN
ATVGAGLPVNHTVRDLRDSGDAILAISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLAGKDVMRKLVILAREAGYDIEPEQVRVESLVPPHCEEGSVDHFFENGDELNE
QMVQRLEAASEMGLVLRYVARFDANGKARVGVEAVRPEHPLAAVLPGDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtgattgcgcaggcagggacgaaggctcgtcagctgcacaaatttggtggcagt
agtctggcggatgtgaagtgttacctccgcgttgcagggatcatggcggagtattcacaa
ccgggcgacatgatggttgtctccgccgcaggcagcaccaccaatcagctgatcaactgg
ctgaaattaagccagactgacaggctctctgcgcatcaggttcagcaatccctgcgtcgt
tatcaaagtgacttgattggcgggctgttgcccgccgatgtggccgatggactgaccagc
gaatttatccacgatctggaacacctggcggcgctactcgacggcggcattaccgacgcg
gtttacgcggaagtggtcggccacggtgaaatctggtcggcgcgcttgatggccgccgta
cttaatcagcaaggccttgatgcggcctggctggatgcccgcgattttctgcgtgccgag
cgttcggcgcagccgcaggtgaacgaaggggcgtcttatccccttttgcagcaaaagctg
gcgcaacatccaggcaaacgcattgttgtcaccggttttatcagccgtaatgaggcgggt
gaaacggtgctgctggggcgtaacggctctgactattcagcaacgcagattggcgcgctg
ggcgatgtttcccgcgtcaccatctggagcgacgtggccggtgtctatagcgccgacccg
cgcaaagtgaaagatgcctgtctgctgccgctgctgcgtctcgatgaagccagcgaactg
gcgcgtcttgccgctccggtactgcatgcccgcacgctgcaaccggtctccggcagcaat
atcgatctgcaattgcgctgtagctataaccccgatcaaggctctacgcggattgaacgc
gtactggcatccggcactggcgcgcgcatcgtgaccagtcacgatgatgtctgtttgatt
gagtttatcgttccggccgggcaggattttaaactggcgcaaaaagagatcgatctgctc
ctcaaacgcgcgcaggcgcgtccgctggcggtgggcgctcatgccgaccgtaatctgctg
caactctgctacacctcggaagtggtcgacagcgtctttaaactgctggatgaagccggt
ctgccgggtgaattacgcctgcgtcaggggctggcgttggtggcgatggtcggtgctggc
gtatgccgtaacccgttgcacagccaccgtttctggcagcaactgaaaggccagccggtt
gagtttatctggcagtccgacgaaggtatcagcctggtcgctgtactgcgcgttggcccg
accgagagcctgattcaggggctgcaccagtcgctgttccgcgcggaaaaacgaatcggt
ctgatgctgttcggcaagggaaatatcggctcccgctggctggagttgttctcccgcgag
cagagcgcgctttcggcgcgtaccgggtttgaatttgtgctggccggcgtggtggatagc
cgccgtagcctgctgaattacgatgggctggatgccagccgtgcgctggctttcttcaat
gatgaagccgtcgagcaggatgaagagtcgctgttcctgtggatgcgcgctcacccgtat
gacgacctggtcgtactggatgtgaccgccagcgagcaactggccgggcagtatctggat
ttcgccagccacggttttcatgtgatcagcgccaacaaactggccggggcgagcacgacc
aataattatcgccagatccacgatgcgtttgaaaagacgggtcgtcactggctgtacaac
gctaccgtcggcgccggattgccggttaaccatacggtgcgcgatctgcgcgatagcggc
gatgcgattctggcgatcagcggtatcttctccggcaccctctcctggttgttcctgcaa
ttcgacggtactgtgccgtttaccgacctggtcgatcaggcgtggcagcaggggctgact
gagccggatccgcgtgtcgatctcgccggtaaagatgtgatgcgcaagctggtgatcctc
gcccgtgaagccggttatgacatcgaacctgagcaggttcgcgtggaatcgctggtgcca
ccgcattgtgaagaaggttcggtggatcacttcttcgaaaacggcgacgaactgaatgaa
cagatggtacagcggctggaagccgccagtgaaatgggccttgtgctgcgttatgttgcg
cgtttcgatgcgaacggcaaagcacgtgtaggcgtggaagcggtccgtccggagcatccg
ctggcggcggttctgccgggtgataacgtcttcgccattgaaagccgctggtatcgcgat
aatccgctggtcattcgcgggccgggcgcagggcgtgatgtcaccgctggcgctatccag
tcagatatcaaccgtctggcgcaattgctgtaa
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