KEGG   Loxodonta africana (African savanna elephant): 100654410
Entry
100654410         CDS       T04351                                 
Symbol
MGST2
Name
(RefSeq) microsomal glutathione S-transferase 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00480  Glutathione metabolism
lav00980  Metabolism of xenobiotics by cytochrome P450
lav00982  Drug metabolism - cytochrome P450
lav00983  Drug metabolism - other enzymes
lav01100  Metabolic pathways
lav01524  Platinum drug resistance
lav05200  Pathways in cancer
lav05204  Chemical carcinogenesis - DNA adducts
lav05207  Chemical carcinogenesis - receptor activation
lav05208  Chemical carcinogenesis - reactive oxygen species
lav05225  Hepatocellular carcinoma
lav05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100654410 (MGST2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100654410 (MGST2)
   00982 Drug metabolism - cytochrome P450
    100654410 (MGST2)
   00983 Drug metabolism - other enzymes
    100654410 (MGST2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100654410 (MGST2)
   05204 Chemical carcinogenesis - DNA adducts
    100654410 (MGST2)
   05207 Chemical carcinogenesis - receptor activation
    100654410 (MGST2)
   05208 Chemical carcinogenesis - reactive oxygen species
    100654410 (MGST2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100654410 (MGST2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100654410 (MGST2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100654410 (MGST2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:lav02000]
    100654410 (MGST2)
Enzymes [BR:lav01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100654410 (MGST2)
Transporters [BR:lav02000]
 Other transporters
  Pores ion channels [TC:1]
   100654410 (MGST2)
SSDB
Motif
Pfam: MAPEG TMEM175
Other DBs
NCBI-GeneID: 100654410
NCBI-ProteinID: XP_003410424
UniProt: G3SWG8
LinkDB
Position
Unknown
AA seq 147 aa
MAGNSILLAAVSLLSAFQQSYFAFQVGKARLKYKVTPPAVTGSPDFERVFRAQQNCVEFY
PVFMLAFWMAGWYFNQALASFLGLVYMYARHQYFFGYSEAVKKRVTGFRLSLVVLALLTF
LGTLGIANSFLDEYLDLNIAKKLRWHL
NT seq 444 nt   +upstreamnt  +downstreamnt
atggctgggaattcaatcctgctggctgctgtgtctcttctctccgcttttcagcaaagt
tattttgcttttcaggtcggaaaggcaagattaaaatacaaagtcacacccccagcagtt
actgggtcaccagactttgagagagtatttcgtgcacaacaaaactgtgtggagttttat
cccgtatttatgcttgcattctggatggctgggtggtatttcaaccaagctttggcaagt
tttctgggtctggtgtacatgtatgcccgtcaccagtacttttttggatattcagaagct
gttaaaaaaagggtcacaggtttccggttgagcctggtggttttggccctgctgaccttc
ttaggcaccctgggcatcgcaaacagctttctggatgaatacctggacctcaatattgcc
aagaaactgaggtggcacctctaa

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