KEGG   Loxodonta africana (African savanna elephant): 100673814
Entry
100673814         CDS       T04351                                 
Symbol
PPP1CA
Name
(RefSeq) LOW QUALITY PROTEIN: serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav03015  mRNA surveillance pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04114  Oocyte meiosis
lav04218  Cellular senescence
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04390  Hippo signaling pathway
lav04510  Focal adhesion
lav04611  Platelet activation
lav04720  Long-term potentiation
lav04728  Dopaminergic synapse
lav04750  Inflammatory mediator regulation of TRP channels
lav04810  Regulation of actin cytoskeleton
lav04910  Insulin signaling pathway
lav04921  Oxytocin signaling pathway
lav04931  Insulin resistance
lav05031  Amphetamine addiction
lav05034  Alcoholism
lav05168  Herpes simplex virus 1 infection
lav05205  Proteoglycans in cancer
lav05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    100673814 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    100673814 (PPP1CA)
   04024 cAMP signaling pathway
    100673814 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    100673814 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100673814 (PPP1CA)
   04218 Cellular senescence
    100673814 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100673814 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100673814 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100673814 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100673814 (PPP1CA)
   04921 Oxytocin signaling pathway
    100673814 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100673814 (PPP1CA)
   04270 Vascular smooth muscle contraction
    100673814 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    100673814 (PPP1CA)
   04720 Long-term potentiation
    100673814 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100673814 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100673814 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    100673814 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100673814 (PPP1CA)
   05034 Alcoholism
    100673814 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100673814 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100673814 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:lav01009]
    100673814 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:lav03021]
    100673814 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:lav03019]
    100673814 (PPP1CA)
   03041 Spliceosome [BR:lav03041]
    100673814 (PPP1CA)
Enzymes [BR:lav01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100673814 (PPP1CA)
Protein phosphatases and associated proteins [BR:lav01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     100673814 (PPP1CA)
Transcription machinery [BR:lav03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     100673814 (PPP1CA)
Messenger RNA biogenesis [BR:lav03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     100673814 (PPP1CA)
Spliceosome [BR:lav03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    100673814 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 100673814
NCBI-ProteinID: XP_010597309
LinkDB
Position
Unknown
AA seq 330 aa
MSDTEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacaccgagaagctcaacttggactccatcatcgggcgccttctggaagtgcaa
ggctcacggcctgggaagaatgtccagctgacagagaacgagatccgtggtctgtgtctc
aagtcgagggagatcttcttgagccagcccattcttctggagctggaggcgcccctcaag
atatgtggtgacatccacggccagtactatgaccttctgcggttgtttgagtacggcggc
tttcctccggagagcaactacctcttcctgggggactacgtggaccggggcaagcagtct
ctggagaccatctgtctgctgctggcctataagatcaagtaccccgagaactttttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctacggcttctatgacgagtgc
aagagacgctacaacatcaagctgtggaaaaccttcaccgactgcttcaactgcctgccc
atcgcggccattgtggatgagaagattttctgctgccatggaggcctatccccagacctg
caatccatggagcagatccggcggatcatgcggcccaccgatgtgcctgaccagggcctg
ctgtgcgacctgctgtggtctgaccccgacaaggacgtgcagggctggggcgagaacgac
cgcggtgtctcctttaccttcggggccgaggtggtggccaagttcctgcacaaacatgac
ttggacctcatttgccgggcgcatcaggtggtggaagacggctacgagttctttgccaag
cggcagctggtgacacttttctcagctcctaactactgtggcgagtttgacaacgctggt
gccatgatgagtgtggatgagactcttatgtgctccttccagatcctcaaacccgccgac
aagaacaaggggaaatacgggcagttcagcggcctgaatcctggaggccggcctatcacc
ccaccccgcaattctgccaaagccaagaaatag

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