Labrus mixtus (cuckoo wrasse): 132984780 Help Entry 132984780         CDS       T10666                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism lmix  Labrus mixtus (cuckoo wrasse) Pathway lmix04020   Calcium signaling pathway lmix04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:lmix00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     132984780 (ryr3)    04020 Calcium signaling pathway     132984780 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lmix04040]     132984780 (ryr3) Ion channels [BR:lmix04040]  Voltage-gated cation channels   Ryanodine receptor    132984780 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 Piezo_TM1-24 DUF913 Motif Other DBs NCBI-GeneID:  132984780 NCBI-ProteinID:  XP_060907710 LinkDB All DBs Position 12:7139744..7268584 Genome browser AA seq 4852 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVATIQKEHHKFCLAAEGLGNRRGYLEATSEAKYVPP DLCVCSFVLEQSLSVRALQEMLANTGQNSEGSADHDKWAGQGGGHRTLLYGHAILLRHSF SGMFLTCLKTSRSLTDKLSFDVGLQEDSIGESCWWTIHPASKQRSEGEKVRIGDDLILVS VSTERYLHLSNSNGNIQVDASFMQTLWNIQPTCSAGNMAVGFLIGGHVMRLCHGHDESLT IPGADKSEKEQTIVNYEAGKGASKARSLWRLEPLRISWSGSHIRWGQAFRLRHLATGNYL ALTEDRGLVLQDREKSDTAATAFCFRPSKEKGDLGPKRDIDGMGVPEIKYGDSVCFVMHV ATGLWLSYMSPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESRAARIIRNTTLLF TNFIKALDSTVDGVSAEVAGYVEEVLQTLNDLIEYFKQPDSELEHEEKQVLLRSLIKRQD LFKEEGMLTLLSKCIDRMNLYDSAAHFGEMAGEEAGAAWKDILNLLYELLAALIRGNRNN CTQFSRNLDWLVSKLERMESSSGILEVLHCILVESPEALNIIQRGHIKSIISLLYKHGRN HKILDVLCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRIVNDVQSIRPNIFLGVADGS AQYKKWYFELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSF DGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGF FFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMQVEPVKEYKRDHEGV RDLLGTTQFLSQASFIPTPVDTSQIVLPAHLDNVRDKLAENIHELWGMNKIELGWTYGKV RDDNKRQHPCLVDFTKLPETERNYNLQMSSETLKTLLALGCHVAQVNVNAEDDLKKIKLP KDYMMSNGYKPAPLDLSEVKLNAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSR RNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEAPHMLDDQSVETTRLFR VEQTYALKTGKWYFEFEALTGGDMRVGWARPGCRPDVELGGDDQAFVFDGYRGRRMHAGS RYFGHPWKTGDVVGCMINMEDKSMIFTLNGELLITSKGSELCFTDFETEDGFIPVCSLGM TQIGRMNLGKDANSFKYYTMCGLQEGFEPFAVNMNREITMWFSKRLPTFVIVPQDHMHIE VTRIDGTVDSPPCLKVTHKTFGTQNSNNDMVYCRLSMPVEFYSADKLLEESMKRSHPPKE DGTVDYGSITTYYHSVRVFAGQDPASVWVGWVSPDYHYHSKNFGLSKTRTVTVTLGDERG RVHESVQRSNCYMVCGADAVGPSSSSRSNSDLEIGCLIDLATGLVSFTANGKELPTTYQV EPNTKLFPAVFVRPTSANLFQFELVKIKDAMPLSSAIFKSEHRNPVPQCPPRLDVQTIVA VLWSRMPNTFLTVETARVSERHGWVVQCLEPLQIMAVHIPEENRCLDILELSEHEDLRKF HYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLISIHLET AKEARLMMNNEFIIPVTDETRSIKLFPDESKRHSLPGVGLSPSLKPRVNFSPVGIISTKR HQFLYSPQIPLGVLKEKAISMLTEAVQGGGIHIRDPVGGSVEYQFVPILKLIGTLLIMGV LTSEEVRRILLLIDPNVFGEAKEGEEGKGDEAAGEKEEVSKNEEKAVEAGEEETKEGKQP VKGLLEKSLPESVKHQMCELLHYFCDCELKHRIESIACFSDSFVSKLQFNQRFRYNELML AFNMSAAVTAKKTKEFRSPPHEQINILLNFSAGEDCPCPEEIQEELNSFHEELRLHCGIP IEEEEEEQDTSIKGRLLALLYKIKGPPQKTEEEPTEQEQAAPTNLKELISQTITSWAQES HIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAINLLVSLGQIRSLLSVR MGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPKMV ASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNNGL ALALEEPDLEKVVTYLAGCGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFVVFCNGESV EENANVVVKLLIRRPECFGPALRGEGGQGLLAAMNEAIKISEDPALDLPPTPAIVSTGSG EEEGEVIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTTDLVGI ISIPLKMPVVNKDGTVTEPDMSASFCPDHKAPMVLFLERVYGIEDQSFLLHMLEVGFLPD LRASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFAGTEHYAQLIDSTLQTIYRL SKGRSLTKAQRDAIEECLLAICKHLRPSMMQQLLRRLVFDVPMLTEYCKIPIRLLTNHYE QNWKYYCLPSGMGSFGIASEEELLLTKKLFWGIFDSLSNKKYDAELFKMAMSCLSAIAGA LPPDFVDASLGATLEKQASVDAQGNFDPKPTNTANISLPEKLEYIANKYAEHSHDKWSSE KVSAGWKHGDTMDDQAKSHPLLKPYKSLSEKERETYRWPVKESLKSMLAMGWNIERTKEG EAMFQQRESEKQKKDSQVNGFSPAPMDLHNVTLSRELQGMVEVVAENYHNIWAKKKKTEL VSKGGGTHPLLVPYDTLTAKEKYRDREKAQELFKFLQISGYVITRGQKDIEQESSSMEKR FSYKFLKRLLKYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLVDQTFKNHC LYFLSTPSKNLSICGCASNKEKEMVTSLFCKLAALVRHRISLFGSDSAMMVSCLHILTNT LDTRTVMKSGSELVKAGVRTFFENAAEDLEKLLEMLKLGKFMQSRAQMKSVSQSITYVTV ALLPILTALFEHIRNSDFGVDLLLNDVQLSCYRILTCFYSLGTGKNVFVEKHLPALGESL AILVAAMPVAFLEPEFNAYNPLSVFNTKTPRERAILSMPDTVEEMCPELPELQKLLKDVN DVSESGARYSDMPQVIEVVLPMLCNYLSYWWEKGPENSPSDADCCTMVTSEHLSIILGNI LKILNNNLGIDDAPWMKRIAVYSQPIICKAGADLLRTHFLPTLDKLRKKTVKVVSEEELL KADGKGDNQEAELLILDEFAVLCRDLYAFYPMLIKYVDNNRSRWLKEPNADSTELFRMVA EIFILWCKSHNFKREEQNFVVQNEINNLGFLTGEGQTKMSKSGGDQERKHKRRRGEYYSI QTSLIVAALKKMLPIGLNMCTPGDQELISVAKIRYSLKDTDDEVKDHLRQNLHLQDKSED PAVQWQLNLYKDVVVKSEEPADPEHTVERVQSISAAVFHLEQVEQPLRNKKCVRHKLLSK QRKRAVVACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEKLVQDLAKTPMKIVE EEEEEVAEIQPDPLHQLILHFSHNALTERSYLEEDPLYIAYADMMAKSCAEDEEEEEEGK EKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKLGISILNGGN VQVQQKMLDYLQEKKDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSIHTKR GSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESI SDFYWYYSGKDVIDETGKVNFSKALDVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVV GFLHVFANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGMIGKQMVDTLVE SSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPEFKGIISKKEFQKSMESQKQYSQSEIEF LLSCAEADENDMFSYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLATFLDLAESV LSYFEPYLGRIEIMGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEGTESEK MEMFVNFCEDTIFEMQLASQISEPDVVDQPEEEEEEEGKSLLDELGGDEGAAESASAFTT ACRSVKKKISNVFEMFSIKNMRKQFKKVKKLSVREIITGFFSFFWMLFTGFFKGIYGLIF GFFHVIWSTMFGGGLVEGAKNIKVTDILGHMPEPTQFGIHGDAVEGEKMEAIELSGSSDS PAPAGEMAEVDMLDMLTAPKREGGGKHVEPGLGDVSELSAESSSADTKKKAATKTVETPE SEKEKSDTEKKEKEDKPKEEQEEAAKETVAEEKAKPKSSQPKEMAPTFMSSVFALLDVIL NKMLNSLTRNFYNLRFLALFVCFAINFILLFYKVTGETEEESDDANSWVSEEEEDDENTL FDMDEFVLHESSGYMLPTLRFLAKFHTVISLLCWVGYYYLKVPLVVFKREKEIARKLEFD GLYITEQPSDEDIKGQWDRLVINTPSFPSNYWDKFIKRKVINKYGDMYGAERIAELLGLD KSALDFDPTVETVEKEASLLSWLSSIDTKYHIWKLGVVLTDNYFLYLIWYTTMSVCGHFN NFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNK SEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDITFFFFVI VILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNL ANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFYPTGDCFRKQYEDQLG NT seq 14559 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaagatgagatccagttcttgagaactgacgatgaggtg gtgctccagtgtgtggccaccatccagaaggagcatcacaagttttgtttggctgctgag ggactcggcaaccgccgcggttacctggaagccacatctgaagcgaagtatgttcctcca gacctgtgtgtttgtagcttcgtgttggagcagtccctgtcagtgcgggccctgcaggag atgctggctaacactgggcagaacagcgaagggagtgctgaccatgacaaatgggcgggt caggggggcggacaccgcaccctgctctatggtcatgccatcctcctccgccactccttc agtggtatgttcctgacctgcttgaagacatcaaggtctcttacagacaagctgtcattt gatgtcggactacaagaagattcaataggagagtcctgctggtggaccatccaccctgcg tccaagcagagatctgaaggagagaaagtccgcatcggagatgacctgatccttgtcagc gtgtcaacagagagatacttgcacctctctaactccaatggcaacatccaggtggatgcc tccttcatgcagaccctctggaacatccagcccacctgctctgcaggaaacatggctgta gggtttttaattggtggacatgtgatgcgtctttgtcatggacacgatgagagtttgacc atcccaggagcagacaagagtgagaaggagcagacaatagtcaactatgaggcgggtaag ggagcatcaaaggcccgctcgctttggagactggagcctctcaggatcagctggagcggt agccacatccgctggggtcaggccttccgactacgccacctcgcaaccggtaattacctg gccctgactgaagaccgaggactggtcctccaggacagggagaagtctgacactgcagcc actgccttctgcttcagaccctcaaaggagaagggagacctgggcccgaagagggacatc gacggcatgggagtccccgagatcaagtacggggactcggtctgcttcgtcatgcacgtc gcgacggggctgtggctgtcctacatgtcgcctgacgccaaatcgtcccgcctggggccg ctgaagagaagggcctgcctgcattctgagggccacatggacgatggtctcatcctgcag cgctgtcaacacgaggagtctcgggctgctcgcatcatccgcaacaccactttactcttc accaacttcatcaaggctttggacagcactgtagatggtgtgtccgcggaggtggccggc tatgttgaggaggtgctgcagactctgaacgacctgatcgagtacttcaaacagcccgat tcagagctggagcacgaggagaagcaggtccttctgcgttcactcatcaaacgtcaagac ctcttcaaagaggagggcatgctgaccctcctgtccaaatgcatcgaccggatgaacctg tacgacagcgccgctcactttggagagatggcgggggaggaggcgggcgcggcgtggaag gacattcttaacctcctctatgaactcctggccgcgctgattcgaggaaacaggaacaac tgcacccagttttcccgcaacttggactggttggtcagcaaactggagagaatggaatct tcatcagggatcctggaagtcctccactgtatcctggtagaaagtcccgaggcgctgaac atcatccagcgaggtcacattaaatccatcatttctctgctctacaagcacgggcgcaac cacaagattctggatgtcctgtgttccctctgtgtttgtaatggggtggcggtgagagcc aatcagaatctgatctgtgacaacctgctccccaagagggacctgctgcttcagactcga atagttaatgatgttcagagcatacggcctaacatcttcctgggcgtggctgacggttcg gctcagtataagaagtggtatttcgagctggtgatcgaccaggtggaccattttgtgacc ggggagccgacccacctgagggtcggctgggccaacactaaaggctacgctccgtacccc ggaggaggagaggggtggggtggaaacggtgtgggagatgacctgtactcgtacagcttt gatggacttcacctctggtcaggccgaatcccaagggcagtggcctccattaaccagcac ctgctgaactcagacgacgtggtcagctgctgtctggatctgggcgctcccagcatgtcc ttcaggatcaacgggcagcctgtccagggcatgttcgaggactttaacaccgatggcttc ttcttccccgtcgtcagcttctctgccggcgtcaaggttcgtttcctgttgggtggacgc catggcgatttcaagttcctgccgcccgccggttactctccgtgctacgaggcgctgctg cctaaagagaagatgcaggtggagcctgtgaaggaatacaagagggaccacgagggggtc cgggacctgctgggtaccactcagttcctctctcaggcgtccttcatccccactccagta gacaccagccagatcgttcttcccgctcacctggacaacgtccgggacaagctggcagaa aacatccacgaactgtgggggatgaacaagatcgagctgggctggacctatggcaaggtt cgagatgacaacaagaggcagcacccgtgcctggtggatttcaccaagctgcctgaaacc gaaaggaattacaacctgcagatgtctagtgaaacactaaagaccctgctggctcttgga tgccatgtcgctcaggtcaatgttaacgctgaggacgatctgaagaaaatcaaacttccc aaagactacatgatgtctaacggttataagcctgcgccactggacctctctgaagtgaag ctgaatgctggtcaggaggttctagttgataaactggccgagaacgcacacaacgtgtgg gccaaagaccgaatcaaacaaggatggacctatggcatccagcaggatttgaagagcagg cgtaatcctcgcctggtgccgtatgctttactggacgagcgtactaagaagtctaacaga gacagtttgagagaggccatcaggactatggtgggatatggatatgacattgacccccca gaccaggaggccccccatatgttggatgatcagagcgtcgagaccacccgcctcttccgt gtggagcagacctacgcactgaagacaggaaagtggtactttgagttcgaggcgctgaca ggaggtgatatgagggttggctgggccaggccgggctgcaggccggacgtggagctggga ggagatgaccaggcctttgtgttcgatggctacaggggtcgacgtatgcacgcaggaagc cgctactttggacacccctggaaaacgggcgacgtggtcggttgcatgatcaacatggag gataaatccatgattttcactctgaacggagagctcctgatcaccagcaagggctctgag ctctgcttcactgactttgagacagaggacggtttcatccccgtgtgcagtctgggcatg actcagatcggacgcatgaacttgggcaaggacgccaactcctttaagtactacaccatg tgtggcctccaggaaggctttgagccctttgctgtcaacatgaacagagagatcaccatg tggttcagcaagcgccttcccacttttgtcattgtacctcaggatcacatgcatatcgag gtcacgaggatcgacgggacggtagacagccctccctgcctcaaggtcacacacaagacg tttggcacacagaacagcaacaacgacatggtctactgtcgtctgagcatgcccgtggag ttctactctgcagacaagttactggaagagtcaatgaaacggagccatcctcccaaagaa gatggaactgttgactatggaagcatcacgacttactaccactcggtgagagtgtttgct ggacaggaccctgcgtcagtgtgggtgggctgggtgtcgcctgactaccattatcacagc aagaacttcggcctcagcaagacgaggaccgtcaccgtcaccctgggagacgagaggggc cgagtccatgagagtgtccagaggagtaactgctacatggtctgtggagcagacgcagtc ggcccgtcttcctccagccgctccaactctgaccttgagatcggctgcctgatcgacctg gccaccgggcttgtgtctttcactgccaacggcaaggagctgcctacaacctatcaggtg gagccaaataccaaactgttccctgccgtgttcgtccgccccaccagtgcaaacctcttc cagtttgaactagtcaagatcaaggatgcaatgccgctctcttctgccatattcaaaagc gagcacaggaacccggtgccgcagtgccctcctcgactggatgtgcagaccatcgtggcc gtgctgtggagccggatgccgaacaccttcctcaccgtggagaccgctcgggtcagcgag agacacggctgggtggtccagtgcctggagccgctgcagataatggccgtgcacatacct gaggagaacaggtgcctggacatcctggagttatcagagcatgaagacctgaggaagttc cactaccacaccttgaagctgtactgcgccctgtgcgcgctgggaaacacccgcgtggcc cacgccctctgcagccacctggaccaatcacagctgctctacaccatcgataaccagtac ctctctgggatgctgagagagggcttctacaatgtcctcatcagcatccatctcgaaacc gcaaaggaggcccgtctaatgatgaacaacgagttcatcatccccgtgacggacgagact cgctccatcaagctcttcccggacgagtccaagcgccactcgcttcccggcgtgggcctg agcccctccctcaagccccgggtcaacttctcccccgtcggcatcatcagcacaaagcgc caccagttcctctacagtccgcagatccccctgggcgtcctgaaggagaaggccatcagc atgctcacggaggccgtgcagggcggaggcattcacatccgagaccccgtgggcggaagc gtcgagtaccagtttgtccccatcctgaagctgatcggaacgctgctgatcatgggggtc ctcaccagcgaggaggtgaggcggattctcctcctgatcgaccccaacgtgttcggcgag gccaaggagggcgaggagggcaagggggacgaggcggcgggggagaaagaggaggtgagc aagaacgaggagaaggccgtggaggcgggggaggaggagacgaaggagggcaaacagccg gtcaaaggtcttctggagaagtcgctgcccgagtccgtcaaacatcagatgtgtgagctg ctgcactacttctgcgactgcgagctgaagcaccgcatcgagtccatcgcgtgcttctcc gacagcttcgtgtccaagctgcagttcaaccagcgcttccgctacaacgagctgatgctg gcgttcaacatgtccgccgccgtcaccgccaagaagaccaaagagtttcgctcccccccg cacgagcagatcaacatcctgttgaatttcagcgccggggaggactgcccctgtcccgaa gagatccaggaagagctcaactccttccatgaggaattgcgactgcactgtggtattccc attgaggaagaggaggaggagcaggacacttccataaaagggcgtctcctcgccttactc tacaagatcaagggtccacctcagaagacagaggaggagcccacagagcaggaacaggct gctcccaccaacctgaaggagctgatctctcagaccatcaccagctgggcgcaggagtct cacatccaggaccccgagctggtcagagtgatgttcagcctgctcaggaggcagtacgat ggcatcggggagcttctccgggccatgaagaaatcctacaccatcagcgccgcttctgtg caggatgctatcaacctgctggtgtctctgggtcagatcagatctctgctgtcagtccgc atggggaaagaggaggagaagcttatgattgatggactcggtgacatcatgaacaacaag gttttctaccagcatcccaacctgatgagagttctgggcatgcatgagaccgtcatggag gtcatggtcaacgtgctgggaggagataaatcccaggagatcgccttccccaagatggtg gccagctgctgtcgtttcttgtgctacttctgtcgtatcagccgccagaaccagaaagcc atgtttgaccatctgagctacctgctggagaacagcagcgtggggctggcctctgaagct atgcgaggctcgactccactggatgttgcagcgtcctcagtgatggacaacaatggcctg gctctggccctggaggagcccgatctggagaaggtggtgacatacctggcaggctgtggg cttcagagctgtgccatgctggttgctaagggttaccctgacctcggctggaaccccata gaaggagagcgctacctgtccttcctgcggttcgtcgtcttctgcaacggtgagagtgtg gaggaaaatgccaacgtggtggtgaagctgctcatcagacgtcctgagtgtttcggcccc gccctgagaggagaggggggtcagggtctgctggctgccatgaatgaggccatcaaaatc tccgaggatcctgccttggacctgcccccgacccccgctatcgtcagtactgggtctggt gaggaagaaggagaagtcatccacatgggcaacgccatcatgtccttctactcggctctt attgacctgctgggacgctgcgctccagagatgcatcttatcaatgcggggaaaggcgag gctctgcgtatcagagccatcctgcgctctctggttccaactactgacctggtgggaatc atcagcatccctctcaaaatgcccgtggttaataaagatgggacagtgacagagccggac atgtcggcctctttctgcccggaccacaaggcccccatggttctcttcctggaacgtgtc tacggcatcgaggaccagagcttcctgctccacatgttggaggtcggcttcctgcctgac ctgcgagcctcggcgtctctcgacacggaggtgttgagcaccaccgagacggcgctggcc atgaacaggtacatcggctcagccctgctgcctctgctgacccgctgtgccgctctgttt gctggtactgagcactacgcacagctgatcgactccacgctgcagaccatctaccggctg tccaaaggccgctcactcacaaaagcccagagggacgccatcgaggagtgtctgctggcc atctgcaagcacctgcgtccctccatgatgcagcagctgctcagacggctggtgtttgac gttcccatgctcactgaatactgcaagatacctatccggctgctgaccaaccactatgag cagaactggaagtactactgcctgccttctggtatgggcagctttggcatcgcctctgag gaggagctcctcctcaccaagaaactcttctggggaatcttcgactccctttctaataag aagtatgatgctgaacttttcaaaatggccatgtcatgtctgagtgccatcgctggagct ctgcctcctgacttcgtcgacgccagtcttggagcaacactggagaaacaggcctctgtg gacgcacagggcaactttgatcccaaacccaccaacactgccaatatctcccttcctgaa aaacttgagtacattgccaacaaatatgcagagcattcccatgacaagtggtcctcagag aaggtgtcagcaggctggaaacatggagacacaatggacgaccaggccaaatcccatcca ctgctgaagccttataaatctctgagtgagaaggagagagaaacgtaccgctggccagtg aaggagtcgttgaagagcatgctggcgatgggatggaacattgagaggaccaaggaggga gaagccatgttccaacaacgagagagtgaaaagcaaaaaaaagattctcaggtgaatgga ttcagtcctgctccgatggacttgcacaatgtaactctgtctagagagttacagggcatg gtggaggtggttgcagagaattaccacaacatctgggccaagaagaagaaaactgaactc gttagcaaaggaggagggacccacccgctgctggttccctatgacaccctgacagctaaa gagaagtacagagaccgagagaaggcccaggagctcttcaagttcctgcagatcagcggc tatgtcatcacaagaggtcagaaggacatcgagcaggaatcatcgtccatggagaagcgt ttctcctacaagttcctcaagaggctgctgaagtacgtcgactctgctcaggagttcatc gctcatcttgaggccatggccaccagtgggaagacagacaaatcccctcacgaccaggaa atcaagttctttgccaaggtgctgctccctctggtggatcaaacttttaagaaccactgt ctctacttcctttctacgcccagcaagaacctgagcatctgtggctgtgcgtccaacaaa gagaaggagatggtcaccagcctgttctgtaagctggcagctcttgtcagacacaggatt tctctctttggtagtgattctgcaatgatggtgagctgtctgcacatcctcacaaacaca ctggacaccagaaccgtgatgaagtccggctcagagctggtcaaagccggggttcggact ttctttgagaacgccgcggaggacctggagaagctgctggagatgctgaagctggggaag ttcatgcagtcgcgtgctcagatgaagagcgtcagccagagcatcacctatgtgaccgtg gctctgctgcccatcctcaccgccctgtttgagcacatcaggaactctgattttggagtt gatctactgttgaatgatgtgcagctctcctgctatcgaatcctcacctgcttctactcc ctgggaacaggaaagaacgtcttcgtggagaagcatcttcctgcactgggggagagcctg gccatcctggtggcggccatgcctgtggcgttcctggagcccgagttcaacgcctacaac ccgctctctgtcttcaacactaagactccccgagaaagagcgattctcagcatgcccgac acagtggaggagatgtgtccggagttgccggaacttcaaaaactgctgaaagatgtcaac gacgtgtcagagtctggtgcccgctacagcgacatgccacaggtcattgaggtggtcctt cccatgctgtgtaactatctgtcctactggtgggaaaaaggccccgagaactcgccttca gatgccgactgctgcaccatggtgacctctgaacacctcagcatcatcctcgggaacatc ctcaagatcctcaacaacaacctgggcatcgacgacgccccctggatgaagaggattgca gtctactctcagccaatcatctgcaaggccggagcagatctgctgaggacccacttcctc cccacgctggacaaactgaggaagaagacggtgaaggttgtgtctgaagaggagctgctg aaggcggacggtaaaggtgacaaccaggaggccgagctgctgatcttggatgagttcgct gtgctctgcagagacctctacgcgttctaccccatgctcatcaaatacgtggacaacaac aggtccaggtggctgaaggagccgaacgcagactccactgagctcttcaggatggtggct gagatcttcatcctctggtgcaagtcccacaactttaagcgagaggagcagaactttgtg gttcagaatgagatcaacaatctgggcttcctgaccggagagggccagacgaagatgtcc aagtcaggaggggaccaggagaggaaacacaagcgtcgtcgaggcgagtattactccatc cagacctctctgatcgtagctgccttgaagaagatgctgcccatcggcctcaacatgtgc accccgggagaccaggagctcatctccgtcgccaagatccgctacagtctgaaagacaca gatgacgaggtgaaggaccacctgagacagaacctccacctccaggacaagtctgaagac ccagcggtccagtggcagctgaatctctacaaggacgtggtggtgaagagcgaggaacca gccgacccggaacacacggtggagcgagtgcagagcatctctgctgcggtcttccacctg gagcaggtggagcagcctctgagaaataagaagtgtgttcggcacaagctgctgtccaaa cagcgtaagcgtgccgtggtggcttgtttccgcatggccccgctctacaatctccccagg catcgcgctatcaacttcttcatcccggcctatcagagactttggatagaggcagaggag tactcctttgaggagaagctagttcaggatctggcaaaaaccccgatgaagatagtggag gaggaggaggaggaggtggctgagatccagccggaccctctccaccagctgattctccac ttcagccacaatgccctgacagagagaagttacttggaagaagatcctttgtatattgca tatgcagacatgatggcaaagagctgtgcagaggatgaggaggaagaggaagaagggaaa gaaaagacgtttgaggaaaaagagatggaaaagcagaagatcctgtatcagcaggcgagg ctgcacgcccgtggggcggctgagatggtgctgcagatgatcagtgccagtaaaggtcgt ctcggccccatggtgacctgcaccctcaaactgggtatctccatcctaaatggaggcaat gtgcaagttcagcagaaaatgcttgattacctgcaggagaaaaaggatgcaggttttttc aagagtctctcgggactgatgcagtcatgcagtgtcctggacttgaacgcatttgagagg cagaacaaagcagaaggacttggcatggtgacagaggaaggttcaatccacacaaagcgg ggttccaaggtgctacagaatgatgagtttactaaagatctattccggtttttgcaactt ctgtgtgaggggcataatggagatttccagaatttcctgagaactcaaactggaaacaca accacagtgaacatcattatcagcactgtggactatctgctccgtcttcaggaatctatc agtgacttctactggtactactctggcaaagacgtcatcgacgagactggaaaagtcaac ttctccaaagctctagatgttgcaaagcagatattcaactcgctgactgagtatattcag ggcccgtgtattggaaaccagcagagtttggctcacagcagactgtgggatgcagtcgtt ggcttcttgcatgtatttgccaacatgcaaatgaagctttcacaggatgctagtcagatc gagctgttgaaggagttgatggatttacagaaagatatggttgtcatgttgctgtctcta ctggagggtaatgtggtgaatggaatgattggaaagcagatggtcgacactttggtggag tcttcgagcaacgtggagatgatcctgaagttcttcgacatgttcctcaaactgaaagac ctgaccacctcggacaatttcaaagagtacgaccccgagttcaaaggcatcatctccaaa aaggagttccagaagtcgatggagagccagaagcagtacagccagtccgagatcgagttc ctgctgtcgtgtgcagaggccgacgagaacgacatgttcagctacaaagagttcgtggag cgattccacgagcccgccaaagatatcggcttcaacgtagcagtgctgttgaccaacctg tcggaacacatgccgcacgactccagactggccaccttcttagacctggcagagagcgtg ctcagctactttgagccgtacctgggccgcattgaaatcatgggcagcgccaagcgtatc gagcgggtgtacttcgagatcagcgagtcgagccgcgagcagtgggagaagccgcaggtc aaagagtccaagcggcagttcatcttcgacgtggtcaacgagggcacggagagcgagaag atggagatgttcgtgaacttctgcgaggacaccatttttgagatgcagctggcctcgcag atctccgagcccgacgtggtggaccaacccgaggaggaggaggaggaggaggggaagagc cttctcgacgagctgggcggagacgagggcgccgcggagtccgcctcggctttcaccacc gcctgccgctccgtaaagaagaagatcagcaatgtcttcgagatgttctcgattaaaaac atgcgcaagcagttcaagaaagtcaagaaactgagcgtcagggagatcatcacaggcttc ttctccttcttctggatgctcttcaccggcttcttcaagggaatctacggcctcatattc gggttcttccacgtcatctggtccaccatgtttggcggcggccttgttgagggagccaag aacatcaaggtcacagacatcctgggacacatgccggaacctactcagtttggtatccac ggcgatgcagttgaaggagagaaaatggaagccatagagttgtcgggaagctcagattca ccagcaccggctggagaaatggcagaggtggacatgttggacatgctgacggcgcccaag agggaaggaggagggaaacatgtggagcccggcctgggtgacgtttctgagctgagtgct gagagctcctctgctgacaccaagaagaaagctgccaccaagactgttgagaccccagag agcgagaaagagaaatcagacacggagaaaaaggagaaggaggataagccgaaggaggag caggaggaggcggcaaaggagacggtggcagaggagaaggccaagcctaaatccagtcag cctaaagagatggcgccgaccttcatgtcgagcgtctttgctctgctggacgtcattttg aacaagatgctgaactccttgactcgtaacttctacaaccttcgtttcctggctctgttt gtgtgtttcgccatcaacttcattcttctcttctacaaggtcactggtgagactgaggaa gaaagcgatgatgcgaacagctgggtcagtgaggaggaggaggatgacgagaacacgctc ttcgacatggatgagtttgtgctgcacgagagctcgggctacatgttacccactctgcgc ttcctggctaaattccacaccgtcatatcactgctctgttgggtcgggtactactatctg aaggttcctttggtggtgttcaagagggagaaggagattgccaggaaacttgagtttgac ggtctctacatcaccgaacagccttcagacgaagacatcaagggccagtgggatcgactc gtcatcaacacgccgtctttccccagcaactactgggacaagtttatcaagcgcaaggtg atcaacaaatacggcgacatgtacggagctgaacgcatcgctgagctcttagggctggat aagagcgctctggactttgacccgacagtggagactgtggagaaggaagcgtctctgctc tcctggctgagctccattgacacaaagtaccacatctggaagctgggagtggttctgact gacaattacttcctgtatctgatctggtacaccaccatgtccgtttgcggacactttaac aacttcttcttcgccgctcatcttctggacatcgccatgggcttcaagactcttcgcacc atcctgtcttctgtcactcacaacggcaagcagctcgtgttgacagtgggtctgctggcc gtggtcgtctatctctacactgtggtggccttcaacttcttcaggaagttctacaacaag agcgaagatgaagatgagcccgacatgaagtgtgacgatatgatgacgtgctacctgttc cacatgtacgtgggcgtgagagctggaggaggcatcggagacgagttggaggacccggct ggagacccctacgagctctaccgcatcctgttcgacatcaccttcttcttctttgtcatt gtcatcctgctggccatcattcagggtttgatcatcgatgcctttggggagctgagagac caacaggagcaggtcaaagaggacatggagaccaaatgcttcatctgcggcatcgggaac gactactttgaccgaacgcctcatgggtttgaaacccacaccttacaagagcacaacctt gcaaactacctgttcttcctcatgtacctgattaacaaggatgagactgaacacacgggt caggagtcgtatgtgtggaagatgtaccaggagagatgctgggacttctaccccactgga gactgcttccgtaagcaatacgaggaccagttgggttaa

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