KEGG   Leptonychotes weddellii (Weddell seal): 102739955
Entry
102739955         CDS       T08708                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww03015  mRNA surveillance pathway
lww04022  cGMP-PKG signaling pathway
lww04024  cAMP signaling pathway
lww04114  Oocyte meiosis
lww04218  Cellular senescence
lww04261  Adrenergic signaling in cardiomyocytes
lww04270  Vascular smooth muscle contraction
lww04390  Hippo signaling pathway
lww04510  Focal adhesion
lww04611  Platelet activation
lww04720  Long-term potentiation
lww04728  Dopaminergic synapse
lww04750  Inflammatory mediator regulation of TRP channels
lww04810  Regulation of actin cytoskeleton
lww04910  Insulin signaling pathway
lww04921  Oxytocin signaling pathway
lww04931  Insulin resistance
lww05031  Amphetamine addiction
lww05034  Alcoholism
lww05168  Herpes simplex virus 1 infection
lww05205  Proteoglycans in cancer
lww05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lww00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    102739955 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    102739955 (PPP1CA)
   04024 cAMP signaling pathway
    102739955 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    102739955 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102739955 (PPP1CA)
   04218 Cellular senescence
    102739955 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102739955 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102739955 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102739955 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102739955 (PPP1CA)
   04921 Oxytocin signaling pathway
    102739955 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102739955 (PPP1CA)
   04270 Vascular smooth muscle contraction
    102739955 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    102739955 (PPP1CA)
   04720 Long-term potentiation
    102739955 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102739955 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102739955 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    102739955 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    102739955 (PPP1CA)
   05034 Alcoholism
    102739955 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    102739955 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    102739955 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:lww01009]
    102739955 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:lww03021]
    102739955 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:lww03019]
    102739955 (PPP1CA)
   03041 Spliceosome [BR:lww03041]
    102739955 (PPP1CA)
Enzymes [BR:lww01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     102739955 (PPP1CA)
Protein phosphatases and associated proteins [BR:lww01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     102739955 (PPP1CA)
Transcription machinery [BR:lww03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     102739955 (PPP1CA)
Messenger RNA biogenesis [BR:lww03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     102739955 (PPP1CA)
Spliceosome [BR:lww03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    102739955 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 102739955
NCBI-ProteinID: XP_006749370
UniProt: A0A2U3Z046
LinkDB
Position
Unknown
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggaaagaatgtacagctaacagagaacgagatccgtggtctgtgcctc
aaatcacgggagatcttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacatccatggccagtactacgaccttctgcggctatttgagtacggcggc
ttccctccagagagcaactacctcttcctgggggactatgtggaccggggcaagcagtct
ttggagaccatctgcctgctgctggcctataagatcaagtaccccgagaactttttcctt
ctgcgtgggaaccacgagtgtgccagcatcaaccgcatctacggcttctatgatgagtgc
aagagacgctacaacattaaactgtggaaaacctttaccgactgcttcaactgcctgccc
attgctgccattgtggacgagaagatcttctgctgccatggaggcttgtccccagacttg
cagtccatggagcagattcggcgtatcatgcggcccacagacgtgcctgaccagggcctg
ctatgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaatgac
cgtggtgtctcctttacctttggggctgaggtagtggccaagttcctgcacaagcacgac
ttggacctcatctgccgggcgcaccaggtggtggaagatggctatgagttctttgccaag
cggcagctggtgacactcttctcggctcctaactactgtggcgagtttgacaacgcaggt
gccatgatgagtgtggatgagacgctcatgtgctccttccagatcctcaagcccgctgac
aagaacaaggggaaatacgggcagttcagtggcttgaaccctggaggccggcccatcacc
ccgccccgcaactccgccaaagccaagaaatag

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