Macaca mulatta (rhesus monkey): 694413 Help Entry 694413            CDS       T01028                                  Symbol OBSCN Name (RefSeq) obscurin isoform X37   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:mcc00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     694413 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mcc01001]     694413 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcc04131]     694413 (OBSCN) Enzymes [BR:mcc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      694413 (OBSCN) Protein kinases [BR:mcc01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    694413 (OBSCN) Membrane trafficking [BR:mcc04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     694413 (OBSCN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_4 C1-set C2-set_2 SOS1_NGEF_PH Adeno_E3_CR1 fn3 RhoGEF PH FN3_DSCAM-DSCAML_C IQ Motif Other DBs NCBI-GeneID:  694413 NCBI-ProteinID:  XP_014970169 Ensembl:  ENSMMUG00000023096 LinkDB All DBs Position 1:85780477..85949920 Genome browser AA seq 6600 aa AA seqDB search MDQSQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIH VREGSEATFRCRVGGSPKPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG TYEVRAENPLGAASAAAALVVDSDAADTASPPGTSTAALLAHLQRRREAMRVEGAPASPP STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILF CKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETQEGSRTVAELAVQG NLLRKLPRKTAVRVGDTAMFCVELAVPVGPVRWVRNQEEVVTGGRVAISAEGTRHTLTIS QCCLEDVGQVVFMAGDCRTSTQFCVSAPRKPPLQPPVDPVVKAKTESSVILSWSPPPHGE RPVTIDGYLVEKKKLGTYTWTRCHDAEWVATPELTVADVAEEGDFQFRVSALNSFGQSPY LEFPGNVHLAPQLAVRTPLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKTSSVFEIR SDGTWHMLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTVHKPPAAAAREVLARL HEEAQLLAELSDQAAAVTWLKDGRMLPPGPKYEVQASAGRRVLLVRDVAREDAGLYECVS CGGRIAYQLSVQGLPCFLHKDMAGSCVDAVAGGPVQFECETSEAHVHVHWYKDGMELGRS GERFLQEDVGTRHRLVAATVTRQDEGIYSCRVGEDSVDFRLRVSEPKAVFAKEQLARREI QAEVGASATLSCEVAQDQTEVTWYKDGKKLSSSSKVHVEAVGCTRRLVVQQAGQADAGEY SCEARGQRISFCLDVAEPKVVFAKEQLAHRKLQAEAGASATLSCKVAQAQTEVMWYKDGK KLSSSSKVRMEATGCTRKLVVQQAGQADAGEYVCEAGGQRLSFHLDVKEPKMMFAKEQSV HNEVWAEAGASAILSCEVAQAQMEVKWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKAD AGEYSCEAGGQRVSFQLHITEPKAVFAKEQSVHNEVQTEAGASATLSCEVVQAQTEVTWY KDGKKLSSSSKVRVEASGCMRQLVVQQAVQADAGEYSCEAGDQRLSFHLDVSEPKVVFAK EQPAHREVQTEAGASATLSCEMAQAQTEVTWYKDGKKLSSSSKVRMEAVGYTRRLVVQQA GQADAGEYSCEAGGKQLSFRLHVAEPKAVFAKEQLVHREVQAQAGASATLNCEVAQAQTE VMWYKDGKKLSSSSKVHVEAEGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAEPKA VFAKEQPVRREVQAELGTSATLSCEMAQAQTEVTWYKDGKKLSSSPKVRMEAVGCTRRLV VQQVGQADAGEYSCEAGGQRLSFGLHVAEPKVVFAKEQPAHRELQAEVGASATLSCEVAQ AQTEVTWYKDRKKLSSSSKVRVEAVGCTRRLVVQQVGQTEAGEYSCEAGGQRLSFRLHVT EPKVVFAKEQPAHREVQAEAGTSTMLSCEVAQAQTEVMWYKDRKKLSSSSKVRVEAVGCT RRLVVQEAGQADAGEYSCEAGGQRLSFHLHVAEPKVVFAKEQPACRVVQAEAGASATLSC VVAQGQMEVTWYKDGKKLSSSSKVHVEAEGCTRRLVVQQAGQADAGEYSCEAGGQWLSFH LHVAGPEPQISERPCRSEPLVVKEHEDIVLTATLATPSVATVTWLKDGVEIRRSKRHETA SQGDTHTLTVHGAQVLDSAVYSCRVGAEGQDFPVQVEEVAAKFCRPLKPVCGELGGTVTL ACELSSACAEVVWRRGSTQLQVGKRFQMVAEGPVRLLTVLELRAEDAGEYVCESRDDHTS AQLTVSVPRVVKFMSGLSAVVAEEGCEATFQCVVSPSDAAVVWFRDGALLQPSEKFAISQ SGTSHSLTISGLVLEDAGQITVEAEGVSSSAVLRVREAPVLFKKKLEPQTVEERSSVTLE VELTRPWPELRWTRNAAALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQA KLTVEMRQVRLIRGLQAVEAQEQGTATMEVQLSHADVEGSWTRDGLRLQQGPTCHLAVRG PTHTLTLSGLRPEDSGLMVFKAEGVHTSALLVVTELPVNFSRPLQDVVTTEKEKVTLECE LSRPNVDVRWLKDGVELRAGKTVGIAAQGTCRSLTIYRCEFADQGMYVCDAHDAQSSASV KVQGRNIQMVRSLEDVEVMEKDSATFSCEVSHDEVPGQWFREGSKLRPSDNVRIRQEGRT YTLIYRRVLAEDAGEIKFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVS RASAQVRWFKGSQELWPGPKYELVSDGLYRKLIISDVQAEDEDTYTCDAGDVKTSAQFFV EEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVH RLMLRRTCSTMTGPVHFTIGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRP APKAVQWYKDDTPLSASEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVE AREVTVTGLLQDAEAMEEGRASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHRGRCHTL VLKSVRRADAGTVCASSPKVSTSAHLEVRVKPVVFLKGLDDLSAEEHGTLALQCEVSDPE AHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDLSPEDAGLYTCHVGSEETQARVSVHDL HVGITKRLKTVEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYIL VVREAAPSDAGEVVFSVRSLTSKASLIVKERPATIMKPLEDQRVAPGEDVELRCELSRAG TPVRWLKDGKAIRKSQKYDVVCEGTMAVLVIRGASLKDVGEYTCEVEASKSTASLCVEEK ANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASRKHQPSQDGLALQLTI SALEKADSDIYTCDIGQAQSQAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYE PVHWFLDKTPLHANELNEIEAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTGK PSVFSRELTDATITEGEDLTLVCETSACDSPVCWTKDGKTLRGSARYQLSHEGHRAQLLI TGATLQDSGRYKCETGGACSSSIVRVHARPVRFQEALKDLEVREGGAATLRCVLSSVAAP VEWRCGDNVLRPGDKYSLRQEGAVLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPA QFIGKLRNKEATEGATATLRCELSKAAPVEWRKGSETIRDGDRYCLRQDGAMCELQIRGL AMVDAGEYSCVCGEERTSASLTIRAMPAHFIGRLRHQESTEGATATLRCELSKVAPVEWR KGRESLRDGDRHRLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALPIKFTE GLRNEEATEGATATLRCELSKVAPVEWWKGHETLRDGDRHSLMQDGARCELQIRGLVAED AGEYLCMCGKERTSAMLTVRALPSKFIEGLRNEEATEGATAILWCELSKVAPVEWRKGHD CLRDGDRHSLKQDGSRCELQIRGLAVVDAGEYSCVCGQERTSAILTVRALPARFIEDVKN QEAREGATAVLQCELSKADPVEWRKGSETLRDGDRYSLRQDGTRCELQIRGLSVADTGEY SCVCGQERTSATLTIRAPQPVFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLR ANGRREPRLQGCTAELVLRGLRREDTGEYTCTCGSQATSATLTVTAAPVRFLQELQPQEV DEGGTAHLRCELSRAGASVEWRKGSLELFPCAKYQMVQDGAAAELLVHGVEQEDAGDYTC DTGHTHSMASLSVRVPRPKFETRLQSLEQETGDIARLCCQLSDAESGATVQWLKEGVELH AGPKYEMRSQGAMRELLIHQLEAKDTGEYACVTGGQKTTASLRVTEPEVTIVRGLVDAEV LANEDVEFSCEVSRAGATGMQWCLQGLPLQSNEVTEVTVQDGRIHTLRLKGVTPEDAGTV SFHLGNCASSAQLTIRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEACWALGGVPL QDNEMNDITVEQGTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNTVVRGLENVE ALEGGEALFECQLSQPEVAAHTWLLDDEPVRTSENAEVVYFENGLRHLLLLKNLRPQDSC RVTFLAGDMVTSAFLTVRGWRLEILEPLKNAVVRAGAQALFTCTLSEVVPVGEASWYING AAVQPDDADWTVTADGSHHALLLRSAQLLHAGEVTFACRDAVASARLTVLGLPDPPEDAE VVACSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGAMGQWRLCHELVPGPECVVDGLAPGE TYRFRVAAVGPVGAGEPVHLPQTVRLATPPKPVPPQPSAPESRQVAAGEDVCLELEVAAE AGEVIWHKGKERIQPSGRFEVVSQGRQQMLVIRGFTAEDQGEYHCGPAQGSTCPAAATFQ VALSPASVDEAPPQPSLPLEAAQEGDLHQLWEALARKRRMSREPTLDSISELPEEDGRSQ HLPQEAEEVAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGRQGTS PLTSKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMDKAAVKIQAAFKGYKVR KEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRACWLKDGVELTDGRHHHIDQL GDGTCSLLITGLGHADAGHYTCQVSNKFGQVAHSACVVVSGTESEAESSSGGELDDAFRR AARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYHEDEHFICIRFEALTEAR QAVTRFQEMFATLGIGVQINLVEEGPRRVEMRISKEAPAPVVPPEPLPSLLTSDAAPVFL TELQNQEVQDGYPVSFDCVVRGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAV VPADMGVYRCLAENSVGVSSTKAELRVDLTSTDYDTAADATETSSYFSAQGYLSSREQEG TESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIHM TDKKTLHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLV PPRMLERFTPKKVKKGSSITFSVKVEGRPAPTVHWLREEAERGVLWIGPDTPGYTMASSA QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLRVSGLSKVEEQEKVKEALISTFLQG TTQAVSAQGLETASFADLGGQRKGEPLAAKEALRHLSLAEVGTEEFLQKLTSQITEMVSA KITQAKLQVPGGDSDDDSKTPSASPRHGRSRPSSSIQESSSESEDGDARGEIFDIYVVTA DYLPLGAEQDAIALREGQYVEVLDAAHPLRWLVRTKPTKSSPSRQGWVSPAYLDRRLKLS PEWGAAEAPEFPGEAVSEDEYKSRLSSVIQELLSSEQAFVEELQFLQSHHLQHLERCPHV PAAVASQKAVIFRNVRDIGLFHSSFLQELQQCDTDDDVAMCFIKNQAAFEQYLEFLVGRV QAESVVVSTAIQEFYKKYAEEALSAGDPSQPPPPPLQHYLEQPVERVQRYQGLLKELIRN KARNRQNCALLEQAYAVVSALPQRAENKLHVSLMEKYPGTLEALGEPIRQGHFIVWEGAP GARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAF EVWQEREDSVRKYLLQARTAIIKNSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGE TVKLACRVTGTPKPVISWYKDGKQVQVDPHHILIEDPDGSCALILDSLTSVDSGQYMCFA ASAAGNCSTLGKILVQVPPRFMNQVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLT PGSKFQTLSEPRSGLLVLVIRAAGKEDLGLYECELVNRLGSTRASAELHIQSPTLQAREQ CHREQLAGAVEVTEQETKVPKKTVIIEETITTVVKSPRGQRRSPSKSPSRSPSRCSASPL RPGLLAPDLLYLPGAGQPRRPEAEPGRKPVVPTLYVTEAEAHSPALPRLSGSQPKWVEVE ETIEVQVKKMGPQGVSPARDVPRSSSGHLFTLPGATPGGDPNSNNSNNKLLAQEAWAQGT AMVSIREPLVFHVDARGSVDWAASDVGSLELEETGVTLEEECTMEEAGEEEGEDGDAFVT EESQDTHSLGDRDPKILTHNGRVLTLADLEDYVPGEGETFRCGGPGPGAPDDPPCEVSVI QREIGEPTVGQPVLLSVGHALGPRGPLGLFRPELRGASPPGPQVRSLEATSFLLPEAPAR PVGSAPWTQSFCTRIRRSVDSGQSSFTTELSTQTINFGTVGETVTLHICPDKDGDEGAQP NT seq 19803 nt NT seq  +upstreamnt  +downstreamnt atggatcagtcacagttcagcggggcgccccgcttcctcacgcggcccaaggccttcgtg gtgtcggtgggcaaggacgccaccctcagctgccagatcgtggggaatcccacgccacag gtgagctgggagaaggaccagcagccggtggcggcgggcgcgcgcttccgtctggcccag gacggcgacctctaccgcctcactatcctggacctggcgctgggcgacagtgggcaatac gtgtgccgcgcgcgcaatgccataggcgaggccttcgccgctgtgggcctgcaggtggac gcggaggccgcctgcgccgagcaggcgccgcacttcctgctgcggcccacgtccatccac gtgcgcgagggctcagaggccaccttccgctgccgcgtgggtggctccccgaagccggca gtgagctggtccaaggacgggcggcgcctgggtgagcccgacggcccccgcgtgcgcgtg gaggagctcggtgaggcgagtgcgctgcgcattcgggcggcgcggccgcgcgacggcggc acttatgaggtccgcgccgagaacccgctgggcgccgccagcgccgccgctgcgctcgtg gtggactcagacgccgcggacactgccagccctcccgggacctccactgccgcgctcttg gcgcacctgcagcggcggcgcgaggccatgcgcgtcgagggcgccccggcctcaccgccc agcaccggcacgcgcacctgcactgtgaccgaaggcaagcacgcgcgcctcagctgctac gtgaccggcgagcccaagcccgagacggtgtggaagaaggacggccagctggtgaccgag ggccggcgtcacgtggtgtacgaggacgcgcaggagaacttcgtgctcaagatcctcttc tgcaagcagtcggaccgcggcctctacacctgcacggcgtccaacctcgtgggccagacc tacagctccgtgctggtcgtagtgcgcgaacccgcggttcccttcaaaaagcggctgcaa gatctggaggtgcgggagaaggagtcggccacgttcctgtgcgaggtgccccagccgtcc actgaggccgcgtggttcaaggaggagacgcggttgtgggcgagcgccaagtacggtatc gaagaggagggcaccgagcgccgcctaaccgtgcgcaatgtctcggccgacgacgacgcg gtgtacatctgcgaaacgcaggagggcagccgcacggtggcggagctcgcagtccaagga aacctcctccgaaagctccctcggaagacggcggtgcgcgtgggcgacacggccatgttt tgcgtggagctggcggtcccggtgggccccgtccgctgggtgcggaaccaggaggaggtg gtgaccgggggccgcgtagccatctccgcagagggcacgcgccacacactgactatctcc cagtgctgcctggaggatgtgggccaggtggtctttatggctggcgactgccggacgtcc actcagttctgcgtgtcggcccccaggaagcctcccctgcagccccctgtggatcctgtg gtgaaggccaagacagagagttccgtgatcctcagctggtccccaccaccccatggggag cgccctgtcaccattgacggctacctggtagagaagaagaaacttggcacctacacatgg accaggtgccacgatgctgaatgggtggctacacctgagctgaccgtggctgatgtggct gaggagggggacttccagttccgagtgtcagctctcaacagctttggtcagagtccctac ctggagttcccggggaatgtccacctggctccccagctggccgtgaggacaccactgaag gcagtgcaggcagtggagggtggcgaggtcactttctctgtggaccttacggtggcctca gcgggtgagtggttcctggatgggcaggccctgaagaccagcagtgtgtttgagatccgc tcggatggcacctggcacatgcttaccatccgggaggtgcctgccagcctgcacggggcg cagctgaagttcgtggccaatggcattgagagcagcatccggatggaggtccgggcggca ccagggctgactgtccacaagccgccagccgcagctgcccgggaggtgctggctcggctg cacgaggaggcgcagttgctggctgagctgtcagatcaggctgcggctgtgacgtggctg aaggatggtcgcatgctgcccccaggccccaagtatgaggtgcaggcatcggccgggagg cgggtgctccttgtgcgagatgtggcccgggaagatgcaggcctctatgagtgcgtcagc tgcgggggccgcatcgcctaccagctgtccgtgcaaggcctcccatgctttctgcacaag gacatggcaggcagctgtgtggatgccgtggctgggggcccggtgcagtttgagtgtgag acctccgaagcccatgtccacgtgcactggtacaaggatggcatggagctgggccgctcc ggtgagcgcttcttgcaggaggatgtggggacgcggcaccggctggtggcagccacagtc accaggcaggatgagggcatctactcctgccgtgtgggcgaggactctgtggactttcgg ctccgcgtctctgagcccaaggcggtgtttgccaaggagcagctggctcgcagggagatt caggccgaggtgggggccagcgccacgctgagctgcgaggtggcccaggaccagacggag gtgacgtggtacaaggatgggaagaagctgagctccagctcgaaagtgcacgtggaggct gtgggctgtacgcggaggctggtggtgcagcaggcgggccaggcagacgctggggagtac agctgtgaggccaggggacagaggatctctttctgcttggacgttgcagagcccaaggtg gtgtttgccaaggagcagctggcacacaggaagctgcaggcagaggcaggagccagtgcc acactgagctgcaaggtggcccaggcccagacagaagtgatgtggtacaaggatgggaag aagctgagctccagctcgaaagtgcgcatggaggccacaggctgcacgcgaaagctggtt gtgcagcaggcaggccaggcggatgccggggagtacgtctgtgaggctgggggccagcgg ctgtccttccatctggacgtcaaagagcccaagatgatgtttgcaaaggagcagtcagtg cataatgaggtgtgggctgaggcgggggccagtgccatattgagctgtgaggtggcccag gcgcagatggaagtgaagtggtacaaggatgggaagaagctgagctctagctcaaaagtg cgcatggaggtcaagggctgcacaaggaggctggtggtacagcaggtgggcaaagcagat gctggggagtacagctgcgaagctgggggccagagggtctcctttcaactacacatcaca gagcccaaggcggtgtttgccaaggagcagtcagtgcataatgaggtgcagactgaggca ggagccagtgccacactgagctgtgaggtggtccaggcccagacggaggtgacatggtac aaggacgggaagaagctgagctccagttcgaaagtgcgtgtagaggcctcaggctgcatg cggcagctggtggtgcagcaggcagtccaggcagatgctggggagtacagctgtgaggcc ggggaccagcggctctccttccacctggatgtttcggagcccaaggtggtgtttgcaaag gagcagccagcacacagggaggtgcagaccgaggcgggagccagtgccacgctgagctgt gagatggcccaggcccagacagaggtgacatggtacaaggatgggaagaagctgagctcc agttcaaaagtgcgaatggaggccgtgggctacacacggaggctggtggtgcagcaggca ggccaggcggacgccggggagtacagctgcgaggccgggggcaagcagctctctttccgc ctgcatgtggcagagcccaaggcggtgtttgccaaggagcagctggtgcacagggaggtg caggcccaggcgggggccagcgccacgctcaactgcgaggtggcccaggcccagacggag gtgatgtggtacaaggacgggaagaagctgagctccagctcgaaagtgcatgtggaggcc gagggctgcacacggaggctggtggtgcagcaggcgggtcaggcagacgctggggagtac agctgcgaggcggggggccagcggctctccttccgcctgcacgtggcagagcccaaggca gtgtttgccaaggagcagccagtgcgcagagaggtgcaggccgaattggggaccagtgcc acgctgagctgcgagatggcccaggcccagacagaggtgacgtggtacaaggacgggaag aaactgagctccagcccgaaagtgcgaatggaggccgtgggctgcacacggaggctggtg gtacagcaagtgggccaggcagacgctggggagtacagctgcgaggccgggggtcagcgg ctctccttcggcctgcacgtggcagagcccaaggtggtgtttgccaaggagcagccggcg cacagggagctgcaggctgaggtgggtgccagtgccacgctgagctgcgaggtggcccag gcccagacggaggtgacatggtacaaggacaggaagaagctgagctccagctcgaaagtg cgtgtggaggccgtgggctgcacacggaggctggtggtgcagcaggtgggccagacagag gctggggaatacagctgcgaggctgggggtcagcggctctccttccgcctacatgtgaca gagcccaaggtggtgtttgccaaggagcagccggcacacagggaggtgcaggctgaggcg gggaccagcaccatgctgagctgcgaggtggcccaagcccagacggaggtgatgtggtac aaggacaggaagaagctgagctctagctcaaaagtgcgcgtggaggccgtgggctgcaca cggaggctggtggtgcaggaggcaggccaggcggatgccggggagtacagctgcgaggct gggggccagcggctctccttccacctacatgtggctgagcccaaggtggtgtttgccaag gagcagccggcatgcagggtggtgcaggcggaggcgggggccagtgccacactgagctgt gtggtggcccagggccagatggaggtgacgtggtacaaggatgggaagaagctgagctcc agctcgaaagtgcacgtggaggccgagggctgcacacggaggctagtggtgcagcaggcg ggccaggcagatgctggggagtacagctgtgaggcggggggccagtggctctccttccac ctgcacgtggcagggccggagccccaaatttcagagagaccctgccgcagtgagcctctg gtggtcaaggagcatgaagacatcgtcctgactgccacgctggccacaccctctgtggcc acagtgacctggcttaaggatggtgtggagattcgccgcagcaagcggcacgagacagcc agccagggggacacccacaccctgaccgtgcatggcgctcaggtgctggacagtgccgtc tacagctgccgtgtgggcgcagaggggcaggacttcccagtgcaggtggaagaggtggcc gccaagttctgccggccgctgaagcctgtgtgcggtgagctgggcggcacggtaacactg gcctgtgagctgagctcagcgtgtgcagaggtggtgtggcgccgtggcagcacgcagctt caggtgggcaagcgcttccagatggtggccgaggggcctgtgcgcttgctcactgtgttg gagctgcgcgcggaggacgcgggggagtacgtatgcgagagccgtgatgaccacaccagt gcgcagctcactgtcagtgtaccccgagtggtgaagtttatgtccgggctgagcgccgtg gtcgcggaggagggctgcgaggccaccttccagtgtgtggtgtcccccagtgatgcggca gtcgtgtggttccgggacggtgccctgctgcagcccagcgagaagtttgccatatcacag agtggcaccagtcacagcctgactatctccggcctggtgctggaggacgcgggccagatc actgtggaggctgagggcgtctcatcctctgctgtcctgagggtccgagaggcgcccgtg ctgttcaaaaagaagctggagccgcagacggtggaggagcggagctcggtgaccctggag gtggagctgacgcggccgtggccggagctgaggtggacacggaacgcggcggccctggcg ccaggaaagaacgtggagatccacgccgagggcgcccgccaccgcctggttctgcacaac gtaggttttgccgaccgtggcttctttggctgcgagactccagatgacaagacacaggcc aaactcaccgtggagatgcgccaggtacggctcatcaggggcctgcaggctgtggaggca caggagcagggcacggctaccatggaggtgcagctgtcgcatgcggacgtggagggcagc tggactcgcgatggtctgcggctccagcaggggcccacgtgccacctggctgtgcggggc cccacacacaccctcacgctctctgggctgaggccagaggacagtggccttatggtcttc aaggccgaaggagtgcacacgtcggcactgctcgtggtcaccgagctgcctgtgaacttc agccgcccgctgcaggatgtggtgaccaccgagaaggagaaggttaccctggagtgtgag ctgtctcgtcctaatgtggatgtgcgctggctaaaggacggtgtggagctgcgggcaggc aagacggtgggcattgcggcccagggcacctgcaggagcctcaccatttaccggtgcgag ttcgcggatcagggcatgtatgtgtgtgatgcccatgacgcccagagctctgcctctgtg aaggtgcaaggccgcaacatccagatggtgaggtcactggaggatgtggaagtgatggag aaggacagtgccaccttctcctgtgaggtctcccacgacgaggtgcctggccagtggttc cgggagggcagcaaactgcggcccagtgacaacgtgcgcatccgccaggaaggaaggaca tacactctcatctaccggagggtcctggcggaagatgcaggagagatcaaatttgtagct gaaaatgcagaatctcgagcccagctccgagtgaaggagctgccagtgaccctcgtgcgc cctctgcgggacaagattgccatggagaagcaccgcggtgtgttggagtgtcaggtgtcc cgggccagcgcccaggtgcggtggttcaagggcagtcaggagctgtggcccgggcccaag tacgagctggtcagtgatggcctctaccgcaagctgatcatcagtgacgtccaggcagag gacgaggacacctacacctgcgacgccggcgatgtcaagactagtgcacagttctttgtg gaagagcaatccatcaccattgtgcggggtctgcaggacgtgacggtgatggagcctgct cctgcctggtttgagtgtgagacctccatcccctcagtgcggccacctaagtggctcctg gggaagacagtgttgcaggctggggggaacgtgggcctggagcaggagggcacagtgcac cggctgatgctgcggcggacctgctccactatgaccgggcccgtgcacttcaccatcggc aagtctcgctcctctgcccgcctggtggtctcagacatccccgtagtcctcacacggccg ttggagcccaagacagggcgtgagctgcagtcagtggtcctgtcctgcgacttccggcca gcccccaaggctgtgcagtggtacaaggatgacacacccctgtctgcctctgagaagttt aagatgagcctggagggtcagatggccgaactgcgcatcctccggctcatgcctgccgat gctggtgtctaccggtgccaggcgggcagcgcccacagcagtactgaggtcactgtggaa gcgcgggaggtgacagtgacagggctgctgcaggatgcagaggccatggaggagggccgg gccagcttctcctgtgagctgtcccatgaggacgaggaggtcgagtggtcgctcaacggg atgcccctgtacaacgacagcttccatgagatctcgcacaggggccggtgccacacgctg gtactgaagagcgtccggcgtgctgatgcaggcacagtatgcgcctcctcccccaaggtg tcaacctctgcccacctggaggtccgagtgaagccggtggtgttcttgaaggggctagat gacctgtccgcagaggagcatggcaccctggccctgcagtgtgaggtctctgaccccgag gcccatgtggtgtggcgcaaagatggcgtgcagctgggccccagcgacaagtatgacttc ctgcacacggcgggcacgcgggggctcgtggtgcatgacctgagccctgaggacgccggc ctgtacacctgccacgtgggctccgaggagacccaggcccgggtcagcgtgcacgatctg cacgtgggcatcaccaagaggctgaagacagtggaggtgctggagggggagagctgcagc tttgagtgcgtcctgtcccatgagagtgccagcgacccagccatgtggacagtcggtggg aagacggtgggcagctccagccgcttccaggccacacgtcagggccgaaaatacatccta gtggtccgggaggctgcgccgagtgatgctggggaggtggtcttctctgtgcggagcctc acctccaaggcctcactcattgtcaaagagaggccggcaaccatcatgaagcccctggaa gaccagcgggtggcgccaggggaggacgtggagctgcgctgtgagctgtcacgggcgggc acgcctgtgcgctggctgaaggatgggaaggccatccgcaagagccagaagtacgatgtg gtctgtgagggcacgatggctgtgttggtcatccgcggggcctcgctcaaggacgtgggc gagtacacgtgtgaggtggaggcttccaagagcacagccagcctctgtgtggaagaaaaa gcaaactgcttcacagaggagctgaccaacctgcaggtggaggagaaaggcacagctgta ttcacgtgcaagacggagcaccccgcggccacagtgacctggcgcaagggcctcttggag ctacgggcctcaaggaagcaccagcccagccaggacggcctggccctgcagctcaccatc agtgccctggagaaggcagacagcgacatctatacctgcgacatcggccaagcccagtct caggcccagctcctcgtgcaaggccggagagtgcacatcatcgaggacctggaggacgtg gatgtgcaggagggctcctcggccaccttccgttgccggatctccccggccaactacgag cctgtgcactggttcctggataagacacccctgcatgccaacgagctcaatgagatcgag gcccagcctgggggctaccacgtgctgaccctgcggcagctggcgctcaaggactcgggc accatctacttcgaggcgggtgaccagagggcctcagccgccctgcgggtcactggtaag ccaagtgtcttctcccgggagctcacagatgccaccatcacagagggtgaggacttgacc ctggtgtgcgagaccagtgcctgcgacagccctgtgtgctggaccaaggatgggaagacc ctgcggggatctgcccggtatcagctgagccacgagggccaccgagcccagttgctcatc actggggccaccctgcaggacagcggacgctacaagtgtgagactgggggcgcctgcagc agctccattgtcagggtgcacgcccggccagtgcggttccaggaggccctgaaggacctg gaggtgcgggagggtggtgctgccacactgcgctgtgtgctgtcatctgtggctgcgccc gtggaatggcgctgtggagacaatgtcctgaggccaggtgacaaatacagcctacgccag gaaggtgctgtgttggagctggtggtccgcaacctccggccgcaggacagcgggcggtac tcatgctccttcggggaccagactacttctgccaccctcacggtgactgccctgcctgcc cagttcattgggaaactgagaaacaaggaggccacagaaggggccacagccacgctgcgg tgtgagctgagcaaggcggcccccgtggagtggagaaaggggtctgagaccatcagagat ggggacagatactgcctgaggcaggacggggccatgtgtgagctgcagattcgtggcctg gccatggtggatgctggggagtactcatgtgtgtgtggagaggaaaggacctcagcctca ctcactatcagggccatgcctgcccacttcataggaagactgagacaccaagagagcaca gaaggagccacagccacactgcggtgtgagctgagcaaggtggcccccgtggagtggagg aagggccgtgagagcctcagagatggggacagacacagactgaggcaggatggggctgtg tgtgagctgcagatctgtggcctggccgtagcagatgctggggagtactcctgtgtgtgt ggggaggagaggacctctgccactctcaccgtgaaggcgctacccatcaagttcacagag ggtctgaggaacgaagaggccacagaaggggcaacggccacactgcggtgtgagctgagc aaggtggcccctgtggagtggtggaaggggcatgagaccctccgagatggagacagacat agcctgatgcaggacggggccaggtgtgagctgcagatccgcggcctggtggcagaggat gctggggagtacctgtgcatgtgcgggaaggagaggacctcagccatgctcaccgtcagg gccctgccttccaagttcatagagggtctgaggaatgaagaggccacagaaggggccacg gccatactgtggtgtgagctgagcaaggtggccccggtggagtggaggaaggggcatgac tgcctcagagatggggacagacacagcctgaagcaggatgggtccaggtgtgagctgcag atccgtggcctggctgtggtggatgccggcgagtactcgtgtgtgtgtgggcaggagagg acctcagccatactcactgtcagggccctgcctgccagattcatagaagatgtgaaaaac caggaggctagagaaggggccacagccgtgctgcagtgtgagctgagcaaggcggatccc gtggagtggaggaaggggtctgagaccctgagagatggggacagatacagcctgaggcag gacgggaccagatgtgagctgcagattcgtggcctgtccgtggcagacactggggagtac tcgtgtgtgtgtgggcaggagaggacctcggccacgctcaccatcagggccccacagcca gtgttccgggagccgctgcagagtctgcaggcagaggagggctccacagccaccctgcag tgtgagctgtctgagcccactgctacagtggtctggagcaagggtggcctgcagctgcgg gccaatgggcgccgggagccacgacttcagggctgcactgcggagctggtgttacggggc ctacgacgtgaagacactggagaatacacttgcacctgtggctcccaggccaccagcgcc accctcactgtcacagctgcccctgtgcggttcctccaagagctgcagccccaggaggtg gatgagggaggcacagcacacttacgctgtgagctgagccgggcgggtgcaagcgtggag tggcgcaagggctccctggagctcttcccttgtgccaagtaccagatggtgcaggatggt gcagctgcggagctgctggtacacggagtggagcaggaggatgcgggtgactacacgtgc gacacaggccacacacacagcatggccagcctctctgtccgtgtccccaggcccaagttc gagacccggctgcagagcctggagcaggagacaggtgacatagcccggctgtgctgtcag ctgagcgatgcagagtcgggtgccacggtgcaatggctcaaggagggtgtggagctgcat gcaggccccaagtacgaaatgcggagccagggggccatgcgggagctgctgatccaccaa ctggaggccaaggacacgggcgagtatgcctgcgtgacaggtggccagaaaaccactgcc tccctcagggtcacagagcctgaggtgaccattgtgcgggggctggttgatgcagaggtg ctggccaatgaggatgttgagttcagctgcgaggtgtccagggctggagccacaggcatg cagtggtgcctacaaggcctgccactgcaaagcaatgaggtgacagaagtgactgtgcag gatggccgcatccacacactgcgactgaagggtgtgacacctgaggatgctggcactgtc tccttccatttgggcaactgtgcttcctccgcccagctcaccatcagagctcctgaggtg accatcctggagcccctgcaggacgtacagctcagtgagggccaggatgccagcttccag tgccggctatccagagcttcaggccaggaagcctgctgggctttaggaggggtgcccctg caggacaacgagatgaatgacatcactgtggagcagggcacactccacctgcttaccctg cacaaggtgacccttgaagatgctggaactgtcagtttccacgtgggcacgtgtagctct gaggcccagctgaaagtcacagccaagaacacagtggtgcgggggctggagaacgtggag gcgctggagggcggcgaggcgctgttcgagtgccagctgtcccagcctgaggtggctgcc cacacctggctgctggacgacgaacctgtgcgcacctcggagaacgccgaggtggtctac tttgagaatggcctgcgccacctgctgctgctcaaaaacttgcggccgcaagacagctgc cgggtgaccttcctggctggggatatggtgacgtccgcgttcctcacggtccgaggctgg cgcctggagatcctggagccgctgaaaaatgcggtggtccgggccggtgcgcaggccctc ttcacctgcacgctcagcgaggtggtgcccgtgggagaggcgtcttggtacatcaatggt gccgcggtgcagccggatgacgccgactggactgtcaccgccgatggcagtcaccacgcc ctactgctgcgcagcgcccagctcctccatgccggggaggtcaccttcgcttgccgcgac gccgtggcttctgcgcgactcaccgtgctgggcctccctgaccccccagaggatgctgaa gtggtggcttgcagcagccacactgtgacactgtcttgggcagctcccatgagtgatgga ggcggtggtctctgtggctaccgcgtggaggtgaaggagggggccatgggccagtggcgg ctgtgccacgagctggtgcctggacctgagtgtgtggtggatggcctggcccccggggag acctaccgcttccgtgtggcagctgtgggcccagtgggtgctggggaaccggttcacctg ccccagactgtgcggcttgcaacgccaccgaagcctgtgcctccccagccctctgcccct gagagccggcaggtggcagctggtgaggatgtctgtctggagcttgaggtggcagctgag gctggcgaggtcatctggcacaagggaaaggagcgcatccagcccagtgggcggttcgag gtggtctcccagggtcggcaacagatgctggtgatcaggggcttcacggcagaagaccag ggcgagtaccactgtggcccagcccagggctccacctgccccgcggctgccaccttccag gtggcgctgagcccagcctctgtggatgaggcccctcctcagcccagcctgccccttgag gcagcccaggagggcgacctgcaccaactatgggaggccctggctcggaaacgtcgcatg agccgtgagcccacgctagactccattagcgagctgcctgaggaggatggccgctcacag cacctgccacaggaggcagaggaggtggcacctgatctctccgaaggctactcaacggct gatgagctggcacgcactggagaggctgacctctcacacaccagctctgatgatgagtcc cgggcaggcaccccttccctggtcacttacctcaagaaggctgggaggcaaggcacctca ccactgaccagcaaggttggggccccagcagccccctctgtgaagccacagcagcagcag gagccgctggctgctgtgcgcccaccgctgggagacctgagcaccaaagacctgggtgat ccctcaatggacaaggcagctgtgaagatccaggccgcctttaagggctacaaggtccgg aaggagatgaagcagcaggaagggcctatgttctcccacacatttggggacaccgaggca caggtaggggatgccctgcggctggagtgtgttgtggccagcaaggcagatgtgcgagcc tgctggctgaaggatggtgtggagctgaccgacgggcggcaccatcacatcgaccagctt ggggatggcacctgttctctgctgatcactggcctgggccatgctgatgctggccactac acctgtcaggtgagcaacaagtttggccaggtggcccacagtgcctgcgtggtggtcagt gggacagagagtgaggccgagagctcctctgggggtgagctggacgatgccttccgccgg gctgcccggcggctgcaccggctcttccgcaccaaaagcccggctgaggtttcagacgag gagctcttcctgagtgcagatgagggccctgcagagccagaggagcctgcggactggcag acataccacgaagatgagcatttcatttgcatccgttttgaggcactcactgaggcccgc caggcggtaactcgcttccaggagatgtttgccacactgggcatcggggtgcagatcaac ctggtggaggaggggcctcggagggtagagatgcgcatcagcaaagaggcccccgcccct gtggtgcctccagagccattgcccagcctactgacttctgatgctgccccggtgttcctg accgagttgcagaaccaagaagtgcaggatgggtatcctgtgagctttgactgtgtcgtg agaggtcagcccatgcctagtgtgcgttggttcaaggatgggaagttgttggaggaggat gaccactacatgattaatgaagaccaacagggtggccatcagctcatcatcacagccgtg gtgccagcagacatgggtgtctaccgctgcctggctgagaacagcgtgggtgtctcctcc accaaggctgagctccgtgtggacttgacaagcacagactatgacactgcagcggatgcc acggagacctcatcctacttcagtgcccaaggctacttgtccagccgggagcaggaggga acagagtccaccactgatgagggccagctgccccaggtggtggaggaactgagagacctc caggtggcccctggcacacgcctggccaagttccagctcaaggtgaaaggctaccctgct cccagattatactggttcaaagatggccagcccctgaccgcatctgcccacatccacatg actgacaaaaagaccctgcacaccctggagatcatctcagtcactcgggaggactctggc cagtatgcggcctacatcagcaatgccatgggtgccgcctactcatctgcccggctgctg gtccgaggccctgatgagccagaagagaagcctgcatcagatgtgcatgagcagctggtg ccaccccgaatgctggagaggttcacccccaagaaagtgaagaaaggctccagcatcacc ttctccgtgaaggtagaaggacgcccggcgcccaccgtgcactggctcagggaggaggct gagaggggtgtgctgtggattggccctgacacgccaggctacaccatggccagctctgca cagcagcacagcctggtcctgctggacgtgggccggcagcaccagggcacctacacgtgc atcgccagcaacgctgccggccaggccctctgctccgccagcctgcgtgtctcgggcctg tctaaggtggaggagcaggagaaagtgaaggaagcactgatttccactttcctgcagggg accacacaagccgtctcagcacaggggttggaaactgcgagttttgccgaccttggtggg cagaggaaaggagagcctctggctgccaaggaggccctcagacacctctcccttgctgag gtgggcacagaggagttcctgcagaaactgacctcccagatcaccgagatggtatcggcc aagatcacgcaggccaagctgcaggtgcctggaggtgacagcgatgatgactccaagaca ccatctgcatccccccgccatggccgatcacggccatcctccagcatccaggagtcttct tcagagtcagaggacggcgacgcccgaggcgagatctttgacatctacgtggtcaccgcc gattacctgcccctgggggctgagcaggatgccatcgcactgcgggaaggccagtacgtg gaggtcctggatgcagcccacccactgcgctggctcgtccgcaccaagcccaccaagtcc agcccctcacggcagggctgggtgtcaccagcctacctggacaggaggctcaagctgtca cctgagtggggggctgctgaggcccctgagttccccggggaggccgtgtctgaagatgaa tacaagtcaaggctgagctctgtgatccaggagctgctgagttctgagcaggccttcgtg gaggagctgcagttcctgcagagccaccacctgcagcacctggagcgctgcccccacgtg cccgcagctgtggccagccagaaggcagtcatcttccgcaatgtgcgggacatcggcctc tttcacagcagcttcctgcaggagctgcagcaatgcgacacagacgacgacgtggccatg tgcttcatcaagaaccaggcagcctttgagcagtacttggagttcctggtggggcgcgtg caggctgagtcggtggtcgtcagcacggccatccaggagttctacaagaaatatgcggag gaggccctgtcagcaggggacccctctcagcccccaccgccacctctgcagcactacctg gagcagccggttgagcgggtgcagcgataccagggcttgctgaaggagctgatccgcaac aaggcgcggaacagacagaactgcgcgctgctggagcaggcctacgccgtggtgtctgcc ctgccgcagcgtgccgagaacaagctgcacgtgtccctcatggagaagtacccgggcacc ctggaggccctgggcgagcccatccgccagggccacttcatcgtgtgggagggtgcacca ggggcccgaatgccctggaagggccacaaccgtcacgtgttcctcttccgcaaccacctg gtaatctgcaagccccggcgagactcccgcaccgataccttcagctacgtgttccggaac atgatgaagctgagcagcatcgacctgaatgaccaggtggagggggatgaccgtgccttt gaggtgtggcaggagcgggaggactcggtgcgcaagtacctgctgcaggcacggacagcc attatcaagaactcgtgggtgaaggagatctgtggcatccagcagcgtctggccctgcct gtgtggcggcccccggactttgaagaggagctggctgactgcacagcggagctcggtgag acagtcaagctggcctgccgcgtgacaggcacacccaagcctgtcatcagctggtacaaa gatgggaaacaagtgcaggtggacccccaccacatcctcattgaagaccctgatggctca tgtgccctcatcctggacagcctgaccagtgtagactcgggccagtacatgtgcttcgcg gccagcgccgctggcaactgcagtaccctgggcaagatcctggtgcaagtcccaccacgg ttcatgaaccaggtccgagcctcgccctttgtggagggagaggatgcccagttcacctgc accatcgaaggcgccccatacccgcagatcaggtggtacaaggacggggccctgctgacc cctggcagcaagttccagacactgagtgagcctcgcagcggcctgctagtgctggtaatc cgggcggctggcaaggaggacctggggctctacgagtgtgagctggtgaaccggctgggc tccacacgagctagtgcagagctgcacattcagagccccacgctgcaggcccgggagcag tgccacagggagcagctcgcaggggcagtggaagtcactgagcaagagactaaagtcccc aagaaaaccgtcatcatagaagagaccatcaccactgtggtgaagagcccacgtggccaa cgacggtcccccagcaagtccccctcccgctcaccttcccgctgctctgccagcccgctg aggccgggcctactggcccctgacctgctgtacctgccaggggctggccagccccgcagg cctgaggcagagccaggccggaagcccgtggtgcccacactgtacgtgacagaggccgag gcccactctccagctctgcccagactctcagggtcccagcccaagtgggtggaggtggag gagaccattgaagtccaggtgaagaagatgggcccgcagggtgtgtctcccgccagagac gtgcccaggagctcatcagggcatctcttcacgctgcccggtgccacccccggaggggac cccaattccaataactccaacaacaagctgctggcccaggaggcctgggcccagggcaca gccatggtcagcatcagagagcccctcgtcttccacgtggatgccagaggcagtgtggac tgggctgcttctgacgtgggcagcctggagctggaggagaccggcgtcaccctggaggag gagtgcaccatggaggaggcgggagaggaagagggggaagacggagatgcctttgtgacg gaggagtcccaggacacacacagccttggggatcgtgaccccaagatcctcacgcacaac ggccgcgtgctgacactggctgacctggaagattacgtgcctggggaaggggagaccttc cgctgtggtggccctgggcccggcgcccctgatgaccctccctgcgaggtctcagtgatc cagagagagatcggggagcccacggtggggcagcctgtgctgctcagtgtggggcatgca ctgggtccccgaggccctctcggcctctttaggcctgagctccgtggggcatcaccacca ggaccccaggtccgtagccttgaggccacctccttcctcttgccggaggccccggctcgg cctgtgggcagtgctccctggacgcagtctttctgcactcgcatccggcgttctgtggac agtggtcagagcagcttcaccacagaactttccacccagaccatcaactttgggacagtg ggggagacggtcacccttcatatctgcccagacaaggatggggatgagggggcacagccc tga

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