Macaca mulatta (rhesus monkey): 721721
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Entry
721721 CDS
T01028
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X13
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04010
MAPK signaling pathway
mcc04020
Calcium signaling pathway
mcc04022
cGMP-PKG signaling pathway
mcc04024
cAMP signaling pathway
mcc04260
Cardiac muscle contraction
mcc04261
Adrenergic signaling in cardiomyocytes
mcc04270
Vascular smooth muscle contraction
mcc04713
Circadian entrainment
mcc04720
Long-term potentiation
mcc04723
Retrograde endocannabinoid signaling
mcc04724
Glutamatergic synapse
mcc04725
Cholinergic synapse
mcc04726
Serotonergic synapse
mcc04727
GABAergic synapse
mcc04728
Dopaminergic synapse
mcc04742
Taste transduction
mcc04911
Insulin secretion
mcc04912
GnRH signaling pathway
mcc04921
Oxytocin signaling pathway
mcc04924
Renin secretion
mcc04925
Aldosterone synthesis and secretion
mcc04927
Cortisol synthesis and secretion
mcc04929
GnRH secretion
mcc04930
Type II diabetes mellitus
mcc04934
Cushing syndrome
mcc04935
Growth hormone synthesis, secretion and action
mcc05010
Alzheimer disease
mcc05020
Prion disease
mcc05022
Pathways of neurodegeneration - multiple diseases
mcc05031
Amphetamine addiction
mcc05207
Chemical carcinogenesis - receptor activation
mcc05410
Hypertrophic cardiomyopathy
mcc05412
Arrhythmogenic right ventricular cardiomyopathy
mcc05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
721721 (CACNA1C)
04020 Calcium signaling pathway
721721 (CACNA1C)
04024 cAMP signaling pathway
721721 (CACNA1C)
04022 cGMP-PKG signaling pathway
721721 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
721721 (CACNA1C)
04929 GnRH secretion
721721 (CACNA1C)
04912 GnRH signaling pathway
721721 (CACNA1C)
04921 Oxytocin signaling pathway
721721 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
721721 (CACNA1C)
04924 Renin secretion
721721 (CACNA1C)
04925 Aldosterone synthesis and secretion
721721 (CACNA1C)
04927 Cortisol synthesis and secretion
721721 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
721721 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
721721 (CACNA1C)
04270 Vascular smooth muscle contraction
721721 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
721721 (CACNA1C)
04727 GABAergic synapse
721721 (CACNA1C)
04725 Cholinergic synapse
721721 (CACNA1C)
04728 Dopaminergic synapse
721721 (CACNA1C)
04726 Serotonergic synapse
721721 (CACNA1C)
04720 Long-term potentiation
721721 (CACNA1C)
04723 Retrograde endocannabinoid signaling
721721 (CACNA1C)
09157 Sensory system
04742 Taste transduction
721721 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
721721 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
721721 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
721721 (CACNA1C)
05020 Prion disease
721721 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
721721 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
721721 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
721721 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
721721 (CACNA1C)
05414 Dilated cardiomyopathy
721721 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
721721 (CACNA1C)
04934 Cushing syndrome
721721 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mcc04040
]
721721 (CACNA1C)
Ion channels [BR:
mcc04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
721721 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
GPHH
Ca_chan_IQ
PKD_channel
DUF4834
Motif
Other DBs
NCBI-GeneID:
721721
NCBI-ProteinID:
XP_015006258
Ensembl:
ENSMMUG00000012988
LinkDB
All DBs
Position
11:2054580..2794705
Genome browser
AA seq
2187 aa
AA seq
DB search
MLRAFVQPGTPAYQPLPSHLSADTEVKFKGTLVHEAQLNYFYISPGGSNYGSPRPAHANM
NANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPK
KQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPED
DSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSA
ILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLH
IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGT
VCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVI
FGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
NEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWN
RFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAE
MLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKI
TRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFD
NFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLA
IAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEMVEKPAVEESKEEKIELKSIT
ADGESPPTTKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEK
AVPMPEASAFFVFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN
HILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA
INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQL
FKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFT
VSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQ
EQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLIL
LNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALI
VVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLL
WTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLF
RCATGEAWQDIMLACMPGKKCAPESEPGNSTEGETPCGSSFAVFYFISFYMLCAFLIINL
FVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGF
GKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDP
FRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKF
KKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAAS
EDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDS
TFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKL
SSKRCHSGESQTAMVGPEETSQDETYEVKMNHDAEACSEPSLLSTDMLSYQDDENRQLTL
PEEDKRDMRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALA
VAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPIPTLRLEGAESSEKLNSSFPSIH
CGSWAETTPGGGDSNTTRRARPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQ
DPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGE
EDAGCARARGRLSEEELQDSRVYVSSL
NT seq
6564 nt
NT seq
+upstream
nt +downstream
nt
atgcttcgagcctttgttcagcctggtacgcctgcataccagccgcttcccagccacctg
tctgccgacacggaggtcaagtttaagggtactttggtgcacgaagctcaactcaactat
ttctacatctctcctggaggttccaactatgggagcccacgccccgcccatgccaacatg
aatgccaatgcggccgcgggactggcccctgagcacatccccaccccgggggccgccctg
tcctggcaggcggccatcgacgcagcccggcaggcgaagctgatgggcagcgctggcaac
gcgaccatctccacagtcagctccacgcagcggaagcggcagcaatatgggaaacccaag
aagcagggcagcaccacggccacacgcccgccccgagccctgctctgcctgaccctgaag
aaccccatccggagggcctgcatcagcattgtcgaatggaaaccatttgaaataattatt
ttactgactatttttgccaattgtgtggccttagcgatctatattccctttccagaagat
gattccaacgccactaattccaacctggaacgagtggaatatctctttctcataattttt
acggtggaagcatttttaaaagtcatcgcctatggactcctctttcaccccaatgcctac
ctccgcaacggctggaatctgctcgattttatcattgtggtcgtggggctttttagcgca
attttagaacaagcaaccaaagcagacggggcgaacgctctcggagggaaaggggccgga
tttgatgtgaaagcgctgagggccttccgcgtgctgcgccccctgcggctggtgtctgga
gtcccaagtctccaggtggtcctgaattccatcatcaaggccatggtccccctgctgcac
atcgccctgctcgtgctgtttgtcatcatcatctatgccatcatcggcctggagctcttc
atggggaagatgcacaagacctgctacaaccaggagggcatagcagatgttccagcagaa
gatgacccttccccttgtgcgctggaaacaggccatgggcggcagtgccagaacggcacg
gtgtgcaagcccggctgggatggtcccaagcacggcatcaccaactttgacaactttgcc
ttcgccatgctcacggtgttccagtgcatcaccatggagggctggacggacgtgctgtac
tggatgcaggacgctatgggctatgagttaccctgggtgtattttgtcagtctggtcatc
tttggatcctttttcgttctaaatctggttctcggtgtgttgagcggagagttttccaaa
gagagggagaaggccaaggcccggggagatttccagaagctgcgggagaagcagcagctg
gaagaggatctcaaaggctacctggactggatcactcaggccgaagacatcgatcccgag
aacgaggacgaaggcatggatgaggagaagccccgaaacatgagcatgcccaccagtgag
actgagtccgtcaacaccgaaaacgtggctggaggtgacatcgagggagaaaactgcggg
gccaggctggcccaccggatctccaagtcaaagttcagccgctactggcgccggtggaat
cggttctgcagaagaaagtgccgtgccgcggtcaagtctaatgtcttctactggctggtg
attttcctggtgttcctcaacacgctcaccattgcctctgagcactacaaccagccccac
tggctcacggaagtccaagacacggcgaacaaggccctgctggcgctgttcacggcagag
atgctgctgaagatgtacagcctgggcctgcaggcctacttcgtgtccctcttcaaccgc
tttgactgcttcgtcgtgtgtggcggcatcctggagaccatcctggtagagaccaagatc
atgtccccactgggcatctccgtgctccgatgcgtccggttgctgaggatattcaagatc
acgaggtactggaactccttgagcaacctggtggcatccttgctgaactctgtgcgctcc
atcgcctccctgctccttctcctattcctcttcatcatcatcttctccctcctggggatg
cagctctttggaggaaagttcaactttgatgagatgcagacccggaggagcacatttgat
aacttcccccagtccctcctcactgtgtttcagatcctgaccggggaggactggaattcg
gtgatgtatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgt
atttacttcatcatcctcttcatctgtggaaactatatcctactgaatgtgttcttggcc
attgctgtggacaacctggctgacgctgagagcctcacatctgcccaaaaggaggaggaa
gaggagaaggagagaaagaagctggccaggactgccagcccagagaagaaacaagagatg
gtggagaagccggcagtggaggaatccaaggaggagaagattgagctgaaatccatcaca
gctgacggagagtctccacccaccaccaagatcaacatggatgacctccagcccaatgaa
aatgaggataagagcccctaccccaacccagagactacaggagaagaggatgaggaggag
ccagagatgcctgtcggccctcgcccacgcccactctctgagcttcaccttaaggaaaag
gcagtgcccatgccagaagccagtgcgtttttcgtcttcagctctaacaacaggtttcgc
ctgcagtgccaccgcattgtcaacgacacgatcttcaccaacctgatcctcttcttcatt
ctgctcagcagcatttccctggctgctgaggacccggtccagcacacctccttcaggaac
cacatcctaggcaatgcagactatgtcttcactagtatctttacattagaaattatcctt
aagatgactgcttatggggcttttctgcacaagggctccttctgccggaactacttcaac
atcctggacctgctggtggtcagcgtgtccctcatctcctttggcatccagtccagtgca
atcaatgtcgtgaagatcttgcgagtcctgcgagtactcaggcccctgagggctatcaac
agggccaaggggctaaagcatgtggttcagtgtgtgtttgtcgccatccggaccatcggg
aacatcgtgattgtcaccaccctgctgcagttcatgttcgcctgcatcggggtccagctc
ttcaagggaaagctgtacacctgttcagacagttccaagcagacagaggcggaatgcaag
ggcaactacatcacgtacaaagacggggaggttgaccaccccatcatccaaccccgtagc
tgggagaacagcaagtttgactttgacaatgttctggccgccatgatggccctcttcacc
gtctccaccttcgaagggtggccagagctgctgtaccgctccatcgactcccacaccgaa
gacaagggtcccatctacaattaccgcgtggagatctccatcttcttcatcatctacatc
atcatcatcgccttcttcatgatgaacatcttcgtgggcttcgtcatcgtcaccttccag
gagcagggggagcaggagtacaagaactgtgagctggacaagaaccagcgacagtgtgtg
gaatacgccctcaaggcccggcccctgcggaggtatatccccaagaaccagcaccagtac
aaagtgtggtacgtggtcaactccacctacttcgagtacctgatgttcgtcctcatcctg
ctcaacaccatctgcctggccatgcagcactacggccagagctgcctgttcaaaatcgcc
atgaacatcctcaacatgctcttcactggcctcttcaccgtggagatgatcctgaagctc
attgccttcaaacccaagcactatttctgtgatgcatggaatacatttgacgccttgatt
gttgtgggtagcattgttgatatagcaatcaccgaggtaaacccagctgaacatacccaa
tgctctccctctatgaacgcagaggaaaactcgcgcatctccatcaccttcttccgccta
ttccgggtcatgcgcctggtgaagctgctgagccgcggggagggcatccggacgctgctg
tggaccttcatcaagtccttccaggccctgccctatgtggccctcctgatcgtgatgctg
ttcttcatctacgcggtgatcgggatgcaggtgtttgggaaaattgccctgaatgatacc
acagagatcaaccggaacaacaactttcagaccttcccccaggccgtgctgctcctcttc
aggtgtgccaccggggaggcctggcaggacatcatgctggcctgcatgccaggcaagaag
tgtgccccggagtccgagcccggcaacagcacggagggtgagacaccctgtggcagcagc
tttgccgtcttctacttcatcagcttctacatgctctgtgccttcctgatcatcaacctc
tttgtagctgtcatcatggacaactttgactacctgacaagggactggtccatccttggt
ccccaccacctggatgagtttaaaagaatctgggcagagtatgaccctgaagccaagggt
cgtatcaaacacctggatgtggtgaccctcctccggcggattcagcccccactaggtttt
gggaagctgtgccctcaccgagtggcttgcaaacgcctggtctccatgaacatgcctctg
aacagcgacgggacggtcatgttcaatgccaccctgtttgccctggtcaggacagctctg
aggatcaaaacagaagagggacccagcccatcagaggcccaccaaggggctgaggatcct
ttccgccctgcagggaacctcgaacaggccaatgaggagctgcgggccatcatcaagaag
atctggaagcggaccagcatgaagctgctggaccaggtggtgcctcctgcaggcgatgat
gaggtcaccgttggcaagttctacgccacattcctgatccaggagtacttccggaaattc
aagaagcgcaaagagcagggtcttgtgggcaaaccctcccagaggaacgcgctgtctctg
caggctggcttgcgcacgctgcacgacatcgggcctgagatccgacgggccatctccgga
gacctcaccgctgaggaggagctggacaaggccatgaaggaggctgtgtccgctgcttct
gaagatgacatcttcaggagggccggtggcctgtttggcaaccacgtcagctactaccaa
agcgacggccggagcgccttcccccagaccttcaccactcagcgcccgctgcacatcaac
aaggcgggcagcagccagggcgacactgagtcgccgtcccacgagaagctggtggactcc
accttcacccccagcagctactcgtccaccggctccaatgccaacatcaacaatgccaac
aacaccgccctgggtcgcctccctcgccctgccggctaccccagcacggtcagcactgtg
gagggccatgggccccccttgtcccctgccatccgggtgcaggaggtggcgtggaagctc
agctccaaaaggtgccactccggggagagccagacagccatggtgggtccggaggagacg
tctcaggatgagacctatgaagtgaagatgaaccatgacgcggaggcctgcagtgagccc
agcctgctctccacagacatgctgtcctaccaggatgacgaaaatcggcaactgacgctc
ccagaggaggacaagagggacatgcggcaatccccaaagaggggtttcctccgctccgcc
tcactaggtcgaagggcctccttccacctggaatgtctgaagcgacagaaggaccgaggg
ggagacatctctcagaagacagtcctgcccttgcatctggttcatcatcaggcattggca
gtggcaggcctgagccccctcctccagagaagccattcccctgcctcattccccaggcct
tttgccacccccccggccacacctggcagccgaggctggccgccacagcccatccccacc
ctgcggctggagggcgccgagtccagtgagaaactcaacagcagcttcccgtccatccac
tgcggctcctgggctgagaccacccccggtggcggggacagcaacaccacccggagagcc
cggcccgtctccctcatggtgcccagccaggctggggccccggggaggcagttccacggc
agtgccagcagcctggtggaagcggtcttgatttctgaaggactggggcagttcgctcaa
gatcccaagttcatcgaggtcaccacccaggagctggcggacgcctgcgacatgaccata
gaggagatggagagcgcggccgacaacatcctcagcgggggcgccccgcagagccccaat
ggcgccctcttaccctttgtgaactgcagggacgcggggcaggaccgagccgggggcgaa
gaggacgcgggctgtgcgcgcgcgcgggggcgcctgagcgaggaggagctccaggacagc
agggtctacgtcagcagcctgtag
DBGET
integrated database retrieval system
