Mugil cephalus (flathead mullet): 124999512 Help Entry 124999512         CDS       T08342                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism mcep  Mugil cephalus (flathead mullet) Pathway mcep04020   Calcium signaling pathway mcep04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:mcep00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     124999512 (ryr3)    04020 Calcium signaling pathway     124999512 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:mcep04040]     124999512 (ryr3) Ion channels [BR:mcep04040]  Voltage-gated cation channels   Ryanodine receptor    124999512 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 Med16_bridge Motif Other DBs NCBI-GeneID:  124999512 NCBI-ProteinID:  XP_047430397 LinkDB All DBs Position 21:3787224..3893394 Genome browser AA seq 4856 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVATVQKEHRKFCLAAEGLGNRLCYLESTSEAKLVPP DMCICNFVLEQSLSVRALQEMLANTGQNSEGSADHEKWAGQGGGHRTLLYGHAILLRHSF SGMYLTCLKTSRSLTDKLSFDVGLQEDSIGEACWWTIHPASKQRSEGEKVRIGDDLILVS VSTERYLHLSNSNGNIQVDASFMQTLWNVQPTCSSGNMAVGYLIGGHVMRLCHGHDESLT IPGADKSEEEQRIVNYEAGKGASKARSLWRLEPLRISWSGSHIRWGQAFRLRHLSTGHYL ALTEDRGLVLQDRAMSDTKSTAFCFRPSKEKSDAGPKRDIDGMGVPEIKYGDSVCFVMHV ATGLWLSYLAPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESRAARIIRNTTFLF TNFIKALDSISEGESSAVAGYVEEVLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQD LFKEEGMLSLLSKCIDRMNLYNSAAHFGEMAGEEAGAAWKDILNLLYELLASLIRGNRNN CTQFSRKLDWLVSKLERLESSSGILEVLHCILVESPEALNIIQRAHIKSIISLLYKHGRN HKILDVLCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGVAEGS AQYKKWYFELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSF DGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGF FFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVKEYKRDHDGV RDLLGTTQFLSQASFIPTPVDTSQIVLPPHLDNIRDKLAENIHELWGMNKIELGWTYGKV RDDNKRQHPCLVDFSKLPETERNYNLQMSSETLKTLLALGCHVSQVNIHAEDDLKKIKLP KDYVMSNGYKPAPLDLSDVKLNAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSR RNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYNIDPPDQEVVHVVDDQSIETIRFFR VEQTYAVKTGKWYFEFEALSGGDMRVGWARPGCRPDVELGMDDQAFVFDGYRGRRLHAGS RYFGQPWKKGDVVGCMINMEDKSMIFTLNGELLITSKGSELGFADFETEDGFIPVCSLSM SQIGHMNLGKDASTFKYYTMCGLQEGFEPFAVNMNRDITMWFSKRLPTFFNVPQDHMHIE VTRIDGTVDSPPCLKVTHKTYGTQNSNNDMVYCRLSMPVEFYSADRLLDESLKLSHPPKE DGSIDYGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYYSKNFGLSKTRTVTVTLGDERG RVHESVQRSNCYMVCGADAVGPSSSSRSNSDLEIGCLIDLATGLVSFTANGKELPTSYQV EPNTKLFPAVFVCPTSANLFQFEFVKIKDAMPLSSAIFKSEHRNPVPQCPPRVDVQTIVA VMWSRMPNTFLNVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDVLELSEHEDLRKF HYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYDVLISIHLET AKEAQLMMNNEFIIPVTDETRSIRLFPDESKRHSLPGVGLSTSLKPRVNFSPVGIINTKR PQFLHSPQIPLGILKEKAITMLTEAVQGGGTHIRDPVGGSAEYQFVPILKLIGTLLITGV LTSDEVRLILLLIDPNVFGESKEGEEAKGDEVAIPGEKEAVSKNEEKAVEAGEEETKESK APVKGLLEKSLPESVKHQMCELLHYFCDCELKHRIESIVSFSDRFVSKLQYNQKFRYNEL MLAFNMSAAVTAKKTKEFRSPPQEQINILLNFSAGEDCPCPEEIQEELNSFHEELRLHCG IPVDEEEEEQDTSIKGRLLALLYKIKGPPHKTEQEPTETEQAAPTNLKELISQTITSWAQ ESHIQDPQLVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAINLLASLGQIRSLLS VRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPK MVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNN GLALALEEPDLEKVVTYLAGCGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFVVFCNGE SVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMREAIKISEDPALDLPKTPAAVTTG SGEEEGEVIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTTDLV GVISIPLNMPVVNKDGTVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLQMLEVGFL PDLRASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFANTEHYAQLIDSTLQTIY RLSKGRSLTKAQRDAIEECLLAICKHLRPSMMQQLLRRLVFDVPMLSEYCKIPIRLLTNH YEQNWKYYCLPSGMGSFGIASEEELLLTKKLFWGIFDSLSHKKYDAELFKMAKACLCAIA GALPPDFVDSSLGTTLEKQASVDAQGNFDPKPINTANISLPEKLEYIANKYAEHSHDKWS SEKMSAGWKHGDNLDEQAKAHPLLKPYKALSEKERETYRWPVRESMKSMLSMGWNIERTK EGEALFQQRESEKQRKISESQGSGFSPAPMDLHNVPLSRELQGMVEVVAENYHNIWAKKK KSELIGKGGGTHPLLVPYDTLTAKEKYRDREKAQELFKFLQISGYTVTRGLKDMEQDSSS MEKRFAYKFLKRLLKYIDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLIDQTF KNHCLYFLSTPSKNLSSCGCASNKEKEMITSLFCKLAALVRHRISLFGSDSAIMVSCLHI LTHSLDTRTVMKSGSELVKAGVRAFFENAAEDLEKLLEMLKLGKFMQSRAQMKSVTQSIN YVTVALLPILTALFDHITTYEFGVDLLLDDVQLSCYRILTCFYSLGTGKNVFVERHLPAL GESLATLVAAMPVAFLEPQLNAHNPRSVFNTKTPRERAILSMPDTVEEMCPEMPRLDKLL KDVNDVSESGARYSDMPQVIEVILPMLCNYLSYWWEKGPENSPPDAQCCTMVTSEHLSII LGNILRILNNNLGIDDAPWMKRIAVYSQPIICKAGADLLRSHFLPTLDKLRKKTVKVVCE EELLKADSKGDNQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKEPDADSTELF RMVAEIFILWCKSHNFKREEQNFVVQNEINNLGFLTGECKSKMSKSGGDQERKHKRRRGE YYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKEHLRQNLHLQD KSEDPAVQWQMNLYKDVVVKSEEPVNSEHTVDRVQSISAAVFHLEQVEQPLRNKKCVMQK LLSKQRKRAVVACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEKLVQDLAKTPM KIVDEEEEEVAEVQPDPLHQLILHFSHNALTERSFLEVDPLYIAYADMMAKSCAEDEEEE EEEEKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGSMVTCTLKLGISI LNGGNVHVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGS IHTDRGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLR LQESISDFYWYYSGKDVIDETGKVNFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRL WDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMV DTLMESSSNVEMILKFFDMFLKLKDLTTSDSFKEYDPEFKGIISKKEFQKSMENQKQYSQ SEIEFLLSCAEADENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLATFLD LAESVLSYFEPYLGRIEIMGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEG GESEKMEMFVNFCEDTIFEMQLASQISEPDVVEQPEEEEQEDGHSILEELSAEEEAALES PSAFTTACRSVKKKIAHVRDMFSLKNVRKQFKKVKKLSIKEIITGFFSFFWMLFIGFFKG IYGLIFGFFHLIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVIEGEKVEAIES TGSLDKAMAPAGDVAEVDMMLEMLSMPKREGGKHVEPGLGDVSELSAESSATDQKKKAAA KPAETPESEPEKADTEKREKEDTPKEEAAKEPVAEEKPKTKSSQPKEAAPAFMSSVFAVL DVYKNKMLNYLARNFYNLRFLALFVCFAINFILLFYKVTGEAEEDADDENQWGGDEEEDD ENTLFDMDEFVLQESTGYMAPTLRFLAIFHTVISLLCVVGYYCLKVPLVVFKREKEIARK LEFDGLYITEQPSDDDIKGQWDRLVINTPSFPSNYWDKFIKRKVINKYGDMYGAERIAEL LGLDKSALDFDPTVETVEKEASLLSWFSSIDTKYHIWKMGVVLTDNNFLYLIWYTTMSIF GHFNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRK FYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDITFF FFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQ EHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPTGDCFRKQYEDLLG NT seq 14571 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaagatgagatccagttcttgcgaactgatgacgaggtg gtgctccaatgtgtggccacagtccagaaggagcaccggaagttctgcttggccgctgag gggctcggaaaccgtctgtgctacctggagtctacatccgaagctaagcttgttcctccc gacatgtgtatttgtaactttgtgctggagcagtccctgtccgtgcgggccctgcaggag atgctggctaacactgggcagaacagcgaagggagtgctgaccatgaaaaatgggcgggt caggggggtggacaccggaccctgctctacggtcatgccatcctcctacgccactccttc agtggcatgtacttgacctgtttgaagacgtcaaggtctctaacagacaagctgtcattc gatgtcggactccaagaagattcaataggagaggcctgctggtggaccattcaccccgcc tccaagcagagatccgagggagagaaagtgcgcatcggagacgacctgattctcgtcagc gtgtcgacggagagatacctgcatctctccaactccaacggcaacatccaggtggatgcc tcgttcatgcagacgctgtggaacgtgcagcccacctgttcttcaggcaacatggctgta gggtatttgatcggcgggcatgtgatgcgtctgtgccacggccacgatgagagcttgacc atccccggagccgacaagagtgaagaggagcagaggatagtgaactacgaggcgggtaag ggagcatcaaaggcccgctcgctgtggagactggagcctctcaggatcagctggagcggc agccacatccgatggggccaggccttccgtctacgccacctctccaccggccactatctg gccctgaccgaagaccgtggactggtcctgcaggacagagcgatgtccgacaccaagtcc acagccttctgcttcaggccctccaaggaaaagagcgacgccggcccaaagagggacatc gacgggatgggcgtcccggagatcaagtacggagactccgtgtgcttcgtcatgcacgtg gcgaccggactgtggctgtcttacctggcccccgacgccaaatcgtctcgtcttggtccc ctgaaacgaagggcctgcctacattctgagggccacatggatgacgggctcatcctccag cgctgtcagcatgaggagtctcgggccgcgcgcatcatccgcaacaccacgttcctcttc accaacttcatcaaggctctggacagcatttctgagggcgagtcctcggcggtggccggg tacgttgaagaggtgctgcagacgctgaacgacctgatcgagtacttcaagcagcccgat tcagagctggagcacgaggagaagcagtgtctgctccgttcgctcatcaaacgtcaagac ctcttcaaagaggagggcatgctgtccctcctgtccaaatgcattgaccggatgaacttg tacaacagtgcagcccacttcggagagatggccggcgaggaggcgggcgcggcgtggaaa gacattctcaacctcctctatgaactcctggcttcgctgatccgcgggaacaggaacaac tgcacccagttttcccggaagttggactggttggtcagcaaactggagagactggagtct tcatcaggaatcctggaagtcctccactgcatcttggtggaaagcccggaggccctgaac atcatccagagagcgcacattaaatcaatcatctctctgctctacaagcatggacgcaac cacaagattctagatgtcctgtgctccctctgcgtttgcaacggggtggcagtgagagcc aatcagaatctgatctgtgacaacctccttccgaagagggacctgctgcttcagactcga ctggtcaatgatgttcagagtatgaggccaaacatctttttgggcgtcgctgagggttca gctcagtataagaagtggtatttcgagctggtcattgaccaggtggaccactttgtgacc ggggaacctacacacctgagagtaggctgggccaacactaaaggctacgctccgtacccc ggcggaggagaggggtggggaggcaacggggttggggatgacctgtactcctacagcttt gatggacttcatctgtggtcaggccgaatcccgagggccgtggcctccattaaccagcac ctgctgaactcggacgacgtggtcagctgctgtctggatttgggcgctcccagcatgtcc ttcaggatcaacgggcagccggtgcagggcatgttcgaggacttcaacaccgacggcttc tttttccccgtcgtcagcttctccgcgggcgtcaaggtccgtttcctgctgggtggacgc cacggagatttcaaattcctgccgcccgccggttactctccgtgttacgaggccctgctg cccaaggagaagatgcacgtggagcccgtgaaggagtacaagagggaccacgacggggtc cgcgatctgctggggaccactcagttcctctctcaggcctccttcatccccactcctgtc gacaccagccagattgttcttccccctcacctggacaacatccgggacaagctggcagaa aacatccatgaactgtgggggatgaacaagattgaactgggctggacctatggcaaggtt cgggatgacaacaagaggcagcacccttgccttgtggatttctcaaagctgcctgaaacc gaaaggaactacaacctgcagatgtccagcgaaacccttaagaccctgttggcactggga tgccacgtttcccaggtcaacattcacgctgaagacgatctgaagaaaatcaaattaccg aaagactatgtgatgtctaacgggtataagcctgcgccactggacctctctgacgtgaag ctgaacgcaggtcaggaggttctagttgataaactggctgagaacgcacacaacgtgtgg gccaaagacagaattaaacaaggatggacctatggcatccagcaggatttgaagagcagg cgtaatcctcgcctggtgccgtatgctttactcgacgaacgcacaaagaaatcaaacaga gacagtctgagagaggccatcaggactatggttggatatggatataatatcgacccccca gaccaagaggtcgtccacgttgtagacgatcagagcatcgagaccatccgcttcttccgc gtggagcagacgtacgcggtgaagacggggaagtggtactttgagtttgaggctctgagc ggcggcgacatgagggtcggctgggcgaggccgggctgcagacctgacgtggagctggga atggacgaccaagccttcgtctttgatggatacaggggtcggcgtttgcatgcaggcagc cgctacttcggacagccctggaagaagggcgacgtggttggttgcatgatcaacatggaa gacaaatccatgatcttcacgctgaacggggagctgctcatcaccagcaagggctccgag ctcggcttcgctgatttcgagacggaagacggtttcatccccgtgtgcagcctcagcatg tctcagatcggccacatgaacctgggcaaggacgccagcaccttcaagtactacaccatg tgcggcctgcaggaaggctttgagccgtttgccgtcaacatgaacagagacatcaccatg tggttcagcaagcgcctgcccacttttttcaacgtgccccaggaccacatgcacattgag gtgacgaggatcgacgggacggttgacagcccaccgtgccttaaggtcacacacaagacg tacggcacccaaaacagcaacaacgacatggtctactgcagactgagcatgccggtggag ttctactctgcagacaggttactggacgagtcactgaaactcagtcatcccccgaaagaa gatggaagcattgactacggcagcatcacaacttactaccactctgtgagggtgtttgcc ggacaggaccccgcctcggtgtgggtgggctgggtcacgcccgactaccattactacagc aagaacttcggcctcagcaagacgcgtacggtcaccgtcaccctgggagacgagaggggc cgggtccacgagagcgttcagaggagtaactgctacatggtgtgcggagcggacgccgtc ggcccgtcgtcctccagccgctccaactctgacctggagatcggctgcctgatcgacctg gccaccggcctcgtctccttcaccgccaacggcaaagagctgcccacgtcgtaccaggtg gagccaaataccaagctcttccccgccgtgtttgtgtgccccaccagcgcgaacctcttc cagttcgagttcgtcaagatcaaggacgccatgccgctgtcctcggccatattcaagagc gagcacaggaacccggtgccgcagtgccccccccgggtggacgtgcagaccatcgtggcc gtgatgtggagccggatgccgaataccttcctcaacgtggagacggctcgggtcagcgaa cggcacggctgggtggtgcagtgtctggaacctctgcagatgatggccgtgcacataccc gaagagaacaggtgtttggacgtcctagagttgtcggagcacgaggacttaaggaagttc cactaccacacgctgaagctgtactgcgctctctgcgctctgggaaacacccgagtagct cacgccctgtgcagccatttggaccagtcgcagcttctctacaccatcgacaaccagtac ctctctggcatgctgagagagggcttctacgacgtcctgatcagcatccatctcgagacg gcgaaggaggcccagctaatgatgaacaacgagttcatcatccccgtgaccgacgagacg cgctccatccggctgttccccgacgagtccaagcgccactcgctgcccggcgtggggctg agcacctccctcaaacctcgggtcaacttctcccccgtgggcatcatcaacaccaagcgg ccgcagttcctgcacagcccccagatcccgctgggcatcctgaaagagaaggccataacc atgctcaccgaggccgtgcaggggggggggacccacatccgggacccggtcggcggcagc gccgagtaccagttcgtccccatcctgaagctcatcgggacgctgctgatcacgggggtc ctgaccagcgacgaggtgaggctgatcctcctcctcatcgaccccaacgtgttcggcgag agcaaggagggcgaggaagcgaagggggacgaggtggccataccgggggagaaggaggcg gtgagcaagaacgaggagaaggctgtggaagccggggaggaggagaccaaggagagcaaa gcgcccgtcaaagggctgctggagaagtcgctgcccgagtccgtcaaacaccagatgtgc gagctgctgcactacttctgcgactgcgagctgaagcaccgcatcgaatccatcgtctcc ttctccgacagattcgtgtccaagctgcagtacaaccagaagttccgctataacgagctg atgctggctttcaacatgtccgccgccgtcaccgccaagaagaccaaagagttccgctca cccccacaggagcagattaacatcctgctgaacttcagcgccggggaggactgcccctgc ccagaggagatccaggaggaactcaactccttccacgaggaactgcgactgcactgtgga attccagtggatgaggaagaggaagagcaggacacgtcgatcaaaggccgactcctcgct ttgctctacaagatcaagggcccacctcataagacagagcaggaacccacagagacggaa caggctgctccgaccaacctgaaggagctcatctcccaaaccataaccagctgggctcag gagtctcacatccaggacccacagctggtcagggtgatgttcagccttctgaggaggcag tatgacggcatcggtgaactgctccgggccatgaagaaatcctacaccatcagcgccgcg tccgtgcaggacgccattaatctgctggcgtccctgggtcaaatcaggtccctgctgtcg gtgcgcatgggcaaagaggaggagaagctcatgattgatggactcggcgacatcatgaac aataaagttttctaccagcatcccaatctgatgagggtgctggggatgcacgagaccgtc atggaggtcatggtcaacgtgttgggtggagacaagtcacaggaaatcgctttccccaaa atggtggccagctgctgtcgcttcctgtgctatttctgtcgcattagccggcagaaccag aaagccatgttcgaccacctgagctacctgctggagaacagcagcgtcggactggcctct gaagctatgcggggctccactccactggatgtcgcagcatcttcagtgatggacaacaac ggcctggctctggccctggaggagcctgatctggagaaggtggtgacatacctggcagga tgcggtctccagagctgcgccatgctggttgccaagggttaccccgacctcggctggaac cccatcgagggagagcgctacctgtccttcctgagattcgtcgtcttctgcaacggtgag agcgtggaggaaaacgccaacgtggtggtgaagctgctgatcagacgcccggagtgtttc ggccccgcgctcagaggagagggcggtcagggtctgctggccgccatgagggaggccatc aagatctccgaggatcctgcgctggacctgcccaagacgcccgccgcagtaacgacaggg tctggtgaggaagaaggagaggtcatccacatgggcaacgccatcatgtccttctactcg gccctcattgacctgctgggacgctgtgcccccgagatgcatctcatcaacgctggtaaa ggcgaggccctgcgtatcagagccatcctgcgctctctggtccccactacagacttggtc ggcgtcatcagcatccccctcaacatgcctgtggttaataaagacggcacagtgacagaa cccgacatgtcggcttgtttctgtccggaccacaaggcccccatggtgctcttcctggac agagtgtacggcatcgaggaccagagcttcctcctccagatgctggaggtcggcttcctg cctgacctgcgagcctcggcgtctctggacacagaagtgctgagcaccacggagaccgcg ttggccatgaacaggtacatcggctcggccctgctgcccttgctgacccgctgcgccgcc ctcttcgccaacacggagcactacgcgcagctgatcgactccaccctgcagaccatctac cggctgtccaaaggccgctcgctcaccaaggcccagagggacgccattgaggagtgtctg ctggctatttgcaaacacctgcgcccctctatgatgcagcagctgctcagacgactggtg tttgacgttccaatgctctctgaatactgcaagatacctatccgcctgctgaccaaccac tatgagcagaactggaagtactattgcctgccgtctggtatgggcagcttcgggatagcc tctgaggaggagctccttctcaccaagaaactcttctggggaatcttcgactccctttct cacaagaagtacgacgccgaacttttcaaaatggccaaggcgtgcctgtgcgccatcgct ggggccctccctccggactttgtggattccagtttggggacaacgctggagaagcaggca tcagtggacgcacagggcaactttgaccccaaacccatcaacactgccaacatctccctt cctgaaaaacttgagtacattgccaacaaatatgccgagcattcccatgataagtggtcc tcagagaagatgtcagcgggctggaagcatggagacaatctggatgagcaggccaaagct catccactcctgaagccgtataaagccttaagcgagaaggagagagaaacgtaccgctgg ccagtgagagagtcaatgaagagcatgttgtctatgggctggaacattgagaggaccaag gagggagaagccctgttccagcaacgagagagcgaaaagcaacgaaagatctcagagtcc cagggttctggattcagccctgctcctatggacctgcataatgtccctttgtccagggag ttacaggggatggtggaggtggtggcagaaaactaccacaacatctgggccaagaagaag aaatctgaactcattggcaaaggaggagggacccacccgctgctggttccctatgacacc ttgactgctaaggagaagtacagagacagagagaaggcccaggaactcttcaagttcctg cagattagtggatacaccgttacaagaggtctaaaggacatggagcaggactcgtcgtcc atggaaaaacgctttgcctacaaattcctcaagaggctgctgaagtacatcgactctgcc caggagttcattgctcatctagaggccatggccaccagcgggaagacggacaaatccccc catgaccaggaaatcaagttcttcgccaaggtgctgcttcctctgatcgatcagaccttt aagaaccactgcctctacttcctgtccacgcccagcaagaacctgagcagctgtggttgt gcctcaaacaaggagaaggagatgatcaccagcctgttctgtaaactggcagctcttgtc agacacaggatttctctctttggaagtgattctgcaattatggtgagctgtctgcacatc ctcactcactcacttgacaccagaacagtgatgaagtctggctcggagctggtcaaggcc ggggtcagggctttctttgagaacgcggccgaggacctggagaagttgctggagatgctg aagctggggaagttcatgcagtcccgcgcccagatgaagagcgtcactcagagcatcaac tacgtgaccgtggctctgctgcccatcctcaccgccctgttcgaccacatcacgacgtat gagtttggagtggacctgcttttggacgacgtgcagctgtcgtgctacaggatcctgacg tgtttctactctctgggaacaggaaagaacgtctttgtggagaggcatctgccagctctg ggggagagcctggcaaccctggtggcggccatgcctgtggcgttcctggagcctcagctg aacgcccacaacccgcgctccgtcttcaacaccaagaccccccgagagagagccatcctg agcatgcccgacaccgtggaggagatgtgtccggagatgcctcgtctagacaagctgctc aaagatgtcaacgacgtctccgagtccggtgctcgctacagtgacatgccacaggtcatt gaggtgatcctccctatgctgtgtaactacctgtcctactggtgggagaaaggcccggag aactcgcccccggatgcccagtgctgcaccatggtgacctctgaacacctcagcatcatt ctgggaaacatcctcaggatcctcaacaacaacctgggcatcgacgacgccccttggatg aagaggatcgcagtctactctcagccgatcatctgcaaagctggagcagatctgctgagg tctcacttcctgcccacactggacaagctgaggaagaagacggtgaaggtggtttgtgaa gaggagctgctgaaggccgacagtaaaggagacaaccaggaggcagagctcctcatcctg gacgagttcgccgtgctctgcagggacctctacgctttctaccccatgctcattcgttac gtggacaacaacaggtccaggtggctgaaggagccggacgcagactccaccgagctcttc aggatggtggctgagattttcatcctgtggtgcaagtcgcacaactttaaacgtgaagag caaaactttgtggttcagaatgagatcaacaacttgggtttcttgaccggtgaatgcaag tcaaagatgtccaagtccggcggggaccaggagaggaaacacaagcggcgccgcggtgaa tactactccattcaaacgtctctgatcgtggctgccctgaagaagatgcttcccatcggc ctcaacatgtgcacccccggagaccaggagctcatctctctggccaagatacgctacagt ctgaaagacacagacgatgaggtgaaggagcatttacgtcagaacctccatcttcaggac aagtctgaagacccagcggttcagtggcagatgaacctctacaaagatgtggtggtgaag agtgaggaaccggtcaactcagagcacacggtggacagagtccagagtatctcagctgca gttttccacctggagcaggtggagcagcctctgaggaacaagaagtgtgtgatgcagaag ctgctgtcgaagcagcgtaagcgtgcggtggtggcttgcttccgcatggctcctctgtac aacctccccaggcatcgcgctatcaacttcttcatcccggcctatcagagactttggata gaggcagaggagtactcctttgaggagaagctagttcaggatctggcaaaaaccccaatg aagattgtggacgaggaggaagaggaggtggctgaggtgcagcccgaccccctccatcaa ctaatcctccacttcagccacaacgctctgacggagagaagtttcttggaagttgatcct ttgtatattgcgtatgcagacatgatggcaaagagctgtgcagaagatgaggaagaagaa gaggaagaagaaaaagagaagacatttgaggaaaaggagatggaaaagcagaagatcctg tatcagcaggcgaggctgcatgcccgcggggccgccgaaatggtgctgcagatgatcagc gccagtaaaggtcgtctgggctccatggtgacctgcaccctcaaactgggcatctccatc ctaaatggaggcaatgtgcatgttcagcagaaaatgcttgattacttgaaagaaaaaaga gatgcaggctttttcaagagtctctcaggactgatgcagtcttgcagcgtcctggacttg aatgcatttgagaggcagaacaaagcagaaggacttggcatggtgacagaggaaggttca atccacactgatcggggctccaaggtgctacagaacgacgagtttaccaaagatcttttc cggtttttgcaacttctatgcgaggggcacaatggagatttccagaatttcctgagaacc cagactggaaacacaaccacagtcaacatcattatcagcacagtagactatcttctccgt ctccaggaatcaatcagtgacttctactggtactactccggaaaagacgtcattgatgaa actggaaaggtgaacttctccaaagctttgtctgtggccaagcagatattcaactcactc actgagtacattcagggcccgtgtatcgggaaccagcagagtttagctcacagcagactg tgggatgcagtggtgggattcttgcatgtatttgcaaacatgcagatgaagctctctcag gattccagtcagattgagctgttgaaggagctgatggatttacagaaggacatggttgtc atgttgctgtctctgctcgagggtaatgtcgtgaatggaacgatcggaaagcagatggtt gacaccctgatggagtcttccagcaatgttgagatgatcctcaagttcttcgacatgttc ctcaagttgaaggatctcacaacctccgacagcttcaaggagtacgaccccgagtttaag ggcatcatttctaagaaggagttccagaagtccatggagaaccagaagcagtacagccag tcggagatcgagttcctgctctcgtgcgcggaggccgacgagaacgacatgttcaattac aaggagttcgtggagcggttccacgagccggccaaagacatcggcttcaacgtggcggtg ctgctcaccaacctgtccgagcacatgccccacgactcccgactcgccaccttcttggac ctggccgaaagcgtgctcagctacttcgagccttacctggggcgcattgaaatcatgggc agcgccaaacggatcgagagggtctactttgagatcagcgagtcgagccgcgagcagtgg gagaagccgcaggtcaaggagtccaagcgtcagttcatcttcgacgtggtcaacgagggc ggcgagagcgagaagatggagatgttcgtcaacttctgcgaggacaccatctttgagatg cagctggcctcgcagatctccgagccggacgtggtcgagcagcccgaggaggaggagcag gaggacggacacagcatcctggaggagctgtccgcagaggaagaggccgctctggagtcg ccctccgccttcaccaccgcctgccgctcggtcaagaagaagattgcgcacgtccgcgat atgttttccctcaaaaacgtgcgcaagcagttcaagaaggtgaagaaactgagcatcaag gagataatcaccggcttcttctccttcttctggatgctcttcatcggcttcttcaagggc atctacggcctcatcttcgggttcttccacctcatctggtcctccatgtttggcggcggg ctagtcgagggagccaagaacatgaaggtgacggacatcctcgggaacatgccggacccg acccagttcggtatccacggagacgtgatagaaggggagaaggtggaggccatagagtcg acgggaagcttggacaaagccatggctccggcgggcgacgtcgccgaggtcgacatgatg ttggagatgctgtcgatgcccaaaagagaaggagggaaacacgtggagcctggcctgggt gacgtttccgagctgagcgccgagtcctccgccaccgaccaaaagaagaaagccgccgcc aagcctgcggaaacccctgagagcgaaccggagaaagcagacactgagaaacgggagaag gaggatacaccaaaggaggaggcggctaaggagccggtggctgaggagaagcccaagacc aaatcgagtcagcccaaagaggctgcgcctgctttcatgtccagtgtctttgctgttctg gacgtctataaaaacaagatgctgaactacctggctcgtaacttctacaacctccgtttc ctggctctgtttgtgtgctttgccatcaacttcattctgctcttctacaaggtcaccggt gaagctgaagaagacgccgacgatgaaaaccagtggggcggagatgaggaggaggacgac gagaacacgctctttgacatggacgagttcgtgcttcaggagagcaccggctacatggcg ccgacgctgcgcttcctggcgatattccacaccgtcatctccctcctctgtgtggtcggc tactactgtctgaaggttcctctggtggttttcaagagggagaaggagatcgccaggaag ctggagtttgacggtctgtacatcaccgagcagccgtctgacgacgacatcaaaggacag tgggatcgactcgtcattaacaccccgtccttcccgagcaactactgggacaagtttatc aagcgtaaggtgatcaacaagtacggcgacatgtacggggccgagcgcatcgccgagctc ctcggcctcgacaagagcgctctggacttcgaccccacggtggagacggtggagaaggag gcgtccctgctgtcctggttcagctccatcgacacaaagtaccacatctggaaaatgggc gtggtgttgactgacaacaacttcctgtatctgatctggtacaccaccatgtccatcttc ggccacttcaacaacttcttcttcgccgctcacctgctggacatcgccatgggcttcaag accctgcgcaccatcctgtcgtccgtcacccacaacggaaagcagctcgtgctgacggtg ggtctgctggccgtggtcgtctatctctacaccgtggtggccttcaacttcttcaggaag ttctacaacaagagcgaggacgaagacgagcccgacatgaagtgcgacgatatgatgaca tgctacttgttccacatgtacgtgggcgtgagggctggaggaggcatcggagacgagctg gaggacccagctggagatccctacgaactctaccgcatcctgttcgacatcaccttcttc ttcttcgtcatcgtcatcctgctggccatcattcagggtttgatcatcgacgccttcggt gaactgagagaccagcaggagcaggtcaaggaggacatggagaccaaatgcttcatctgt ggcatcggcaacgactacttcgaccggacgcctcacgggtttgaaacccacaccttacaa gagcacaacctcgccaactacctgttcttcctgatgtacctgattaacaaggatgagact gagcacacgggccaggagtcctacgtgtggaaaatgtaccaggagagatgctgggacttc ttccccaccggagactgcttccgtaaacaatacgaggacctgctgggttaa

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