KEGG   Macaca fascicularis (crab-eating macaque): 102137531
Entry
102137531         CDS       T02918                                 
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
  KO
K05730  guanine nucleotide exchange factor VAV
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf04015  Rap1 signaling pathway
mcf04024  cAMP signaling pathway
mcf04062  Chemokine signaling pathway
mcf04510  Focal adhesion
mcf04517  IgSF CAM signaling
mcf04650  Natural killer cell mediated cytotoxicity
mcf04660  T cell receptor signaling pathway
mcf04662  B cell receptor signaling pathway
mcf04664  Fc epsilon RI signaling pathway
mcf04666  Fc gamma R-mediated phagocytosis
mcf04670  Leukocyte transendothelial migration
mcf04810  Regulation of actin cytoskeleton
mcf05135  Yersinia infection
mcf05205  Proteoglycans in cancer
mcf05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102137531 (VAV2)
   04024 cAMP signaling pathway
    102137531 (VAV2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102137531 (VAV2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102137531 (VAV2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102137531 (VAV2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    102137531 (VAV2)
   04660 T cell receptor signaling pathway
    102137531 (VAV2)
   04662 B cell receptor signaling pathway
    102137531 (VAV2)
   04664 Fc epsilon RI signaling pathway
    102137531 (VAV2)
   04666 Fc gamma R-mediated phagocytosis
    102137531 (VAV2)
   04670 Leukocyte transendothelial migration
    102137531 (VAV2)
   04062 Chemokine signaling pathway
    102137531 (VAV2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102137531 (VAV2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102137531 (VAV2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102137531 (VAV2)
SSDB
Motif
Pfam: RhoGEF CAMSAP_CH SH3_2 CH SH3_1 SH3_9 SH2 SOS1_NGEF_PH PH C1_1 RHG20_PH DUF7145 C1_2 PLU-1 CDC24 SH2_2 PH_10 DH_Alsin zf-RING-like
Other DBs
NCBI-GeneID: 102137531
NCBI-ProteinID: XP_005580547
Ensembl: ENSMFAG00000004024
LinkDB
Position
15:join(5371865..5372068,5427037..5427153,5504690..5504748,5532503..5532571,5555365..5555467,5558036..5558050,5559096..5559194,5560992..5561060,5562115..5562215,5571199..5571298,5572354..5572449,5573460..5573528,5577107..5577193,5579844..5579929,5580704..5580836,5581918..5581932,5583207..5583316,5584650..5584751,5585480..5585568,5588471..5588487,5589246..5589267,5590298..5590425,5591685..5591759,5593076..5593128,5594114..5594230,5597207..5597294,5598754..5598877,5599737..5599823,5600655..5600809,5604568..5604615)
AA seq 878 aa
MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDI
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSI
AQNKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDGGDDIYEDIIKVEV
QQPMIRYMQKMSMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAV
FINLEDLIKVHHSFLRAIDVSMMVGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQL
LASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLK
EALEAMQDLAMYINEVKRDKETLRKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNH
TKQDRYLFLFDKVVIVCKRKGYSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFY
LIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKAC
KMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGPGPKMVAMQNYHGN
PAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISR
PPSREIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHI
KVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERSASRASSR
SPASCASYNFSFLGPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMRELSLREG
DVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ
NT seq 2637 nt   +upstreamnt  +downstreamnt
atggagcagtggcggcagtgcggccgctggctcatcgactgcaaggtcctgccgcccaac
caccgggtggtgtggccctcggccgtggtcttcgacctggcgcaggcgctgcgcgacggg
gttctcctgtgccagctgctgcacaacctctcccccggctccatcgacctcaaggacatc
aacttccggccgcagatgtcccagttcctgtgtttgaagaacatacggaccttcctgaaa
gtctgccacgataaatttggattaaggaacagtgagctgtttgacccctttgacctcttc
gatgtgcgagactttggaaaggtcatctccgcggtgtcgaggctctcactgcacagcatt
gcgcagaacaaaggaatcaggccttttccctcagaggagaccacagagaatgacgatgac
gtctaccgcagcctggaggagctggcggatgagcatgacctgggggaggacatctacgac
tgcgtcccgtgtgaggatggaggggacgacatctacgaggacatcatcaaggtggaggtg
cagcagcccatgattagatacatgcagaaaatgagcatgactgaggatgataaaaggaac
tgctgcctgctggagatccaggagaccgaggccaagtactaccgcaccctggaggacata
gagaagaactacatgagccctctgcggctggtgctgagcccggcggacatggcggctgtc
ttcattaacctggaggacctgatcaaggtgcatcacagcttcctgagggccatcgacgtg
tccatgatggtggggggcagcacgctggccaaggtctttctcgatttcaaggaaaggctc
ttgatctacggggagtactgcagccacatggagcacgcccagaacactctgaaccagctc
ctggccagccgggaggacttcaggcagaaagtcgaggagtgcacgctgaaggtccaggat
ggaaaatttaaactacaagacctgctggtggtccccatgcagagggtgctcaaataccac
ctgctcttgaaggagcttctgagccattctgcggaacggcctgagaggcagcagctcaaa
gaagcactggaagctatgcaggacttagcgatgtacatcaatgaagttaaacgggacaag
gagaccttgaggaaaatcagcgaatttcagagttctatagaaaacttgcaagtgaaactg
gaggaatttggaagaccaaagattgacggggaactgaaagtccggtccatagtcaaccac
accaagcaggacaggtacttgttcctgtttgacaaggtggtcatcgtctgcaagcggaag
ggttacagctacgagctcaaggagatcatcgagctgcttttccacaagatgaccgatgac
cccatgaacaacaaggacgtcaagaagtctcacgggaaaatgtggtcctacggcttctac
ctaattcaccttcaaggaaagcaaggtttccagtttttctgcaaaacagaagatatgaag
aggaagtggatggagcagtttgagatggccatgtcaaacatcaagccggacaaagccaat
gccaaccaccacagtttccagatgtacacgtttgacaagaccaccaactgcaaagcctgc
aaaatgttcctcaggggcaccttctaccagggatacatgtgcaccaagtgtggcgtcggg
gcacacaaggagtgcctggaagtgatacctccctgcaagtttacttctcctgcagatctg
gacgcctccggagcgggaccaggtcccaagatggtggccatgcagaattaccatggcaac
ccagcccctcccgggaagcctgtgctgaccttccagacgggcgacgtgcttgagctgctg
aggggtgaccctgagtctccgtggtgggagggtcgtctggtgcaaaccaggaagtcaggg
tatttccccagctcatctgtgaagccctgccctgtggatggaaggccgcccatcagccgg
ccgccgtcccgggagatcgactacactgcatacccctggtttgcaggtaacatggagagg
cagcagacggacaacctgctcaagtcccacgccagcgggacctacctaatcagggagcgg
cctgctgaggctgagcgctttgcaataagcatcaagttcaacgatgaagtgaagcacatc
aaggtggtggagaaggacaactggatccacatcacagaagccaagaaattcgacagcctc
ctggagttggtggagtactaccagtgccactcactcaaggagagcttcaagcagctggac
accacactcaagtacccctacaagtcccgggaacgctcggcctccagggcctccagccgg
tccccagcttcctgtgcttcctacaacttttcttttctcggtcctcagggcctcagcttt
gcttctcagggcccctccgctcccttctggtcagtgttcacgccccgcgtcatcggcacg
gctgtggccaggtacaactttgctgcccgagacatgagagagctttcgctgcgggagggt
gacgtggtgaggatctacagccgcatcggcggggaccagggctggtggaagggcgagacc
aacggacggattggctggtttccttcaacgtacgtagaagaggagggcatccagtga

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