KEGG   Mycobacterium canettii CIPT 140070017: BN45_60035
Entry
BN45_60035        CDS       T02422                                 
Symbol
nrdE
Name
(GenBank) Ribonucleoside-diphosphate reductase 2, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
mcz  Mycobacterium canettii CIPT 140070017
Pathway
mcz00230  Purine metabolism
mcz00240  Pyrimidine metabolism
mcz01100  Metabolic pathways
mcz01232  Nucleotide metabolism
Module
mcz_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
mcz_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mcz00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    BN45_60035 (nrdE)
   00240 Pyrimidine metabolism
    BN45_60035 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mcz03400]
    BN45_60035 (nrdE)
Enzymes [BR:mcz01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     BN45_60035 (nrdE)
DNA repair and recombination proteins [BR:mcz03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    BN45_60035 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-ProteinID: CCK65236
LinkDB
Position
complement(3510975..3513056)
AA seq 693 aa
MLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYS
RNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGD
TALAELLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRVEDNMESIGRSINSALQLS
KRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHA
HHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVP
FADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIEGK
ITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRA
LTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSEEGIDFTNIYFYIV
LYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIP
TQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVY
YPAPYMTNDNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQI
YAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML
NT seq 2082 nt   +upstreamnt  +downstreamnt
atgctgaacctgtacgacgcggacggcaagatccagttcgacaaggatcgggaagcagcc
caccagtactttttgcagcacgtcaatcagaacacggtcttcttccataatcaggacgag
aagctcgactacctgatccgcgagaattactacgagcgtgaggttctcgaccagtactcg
cgcaacttcgtcaagacgctgctagaccgcgcctacgccaaaaagttccggtttccgacg
tttttgggtgcgttcaagtactacacctcctacacgctgaaaacctttgacgggaagcgc
tatctggagcgcttcgaggaccgcgtggtcatggtggcgctaacgttggccgccggtgat
accgcacttgccgagctgctggtcgacgagatcatcgacggccgcttccagcccgccaca
ccgacgtttttgaattctggcaagaagcagcgcggggagcccgtgagctgttttttgctt
cgcgtcgaagacaacatggagtcgatcggacggtcgatcaactccgcgctgcagctatcc
aagcgtggcgggggagtggcgttgctgctgaccaacattcgcgagcacggcgcgccgatc
aagaacatcgagaaccagtcctcgggcgtcatccccatcatgaagttgctggaggatgcg
ttctcctacgccaaccagctgggcgctcgtcagggtgccggcgcggtgtacctgcacgcc
catcaccccgacatctaccgattcctggacaccaagcgtgagaacgccgacgagaagatc
cggatcaagacgctgagcctgggggtggtgatccccgacatcaccttcgagttggccaag
cgcaacgatgacatgtacctgttctcgccctacgatgtcgagcgggtctacggtgtgccg
ttcgctgacatctcggtcaccgagaagtactacgaaatggtcgatgacgcgcgcatccgc
aagaccaagatcaaggcacgggagttcttccagacgctggccgagctgcagttcgagtcc
ggctacccctatatcatgttcgaagacaccgtcaatcgcgctaatccaattgagggcaag
atcacgcactccaacctgtgctcggagatcctgcaagtgtctacgccgtcattgttcaac
gaggacttgtcgtatgccaaagtgggcaaagacatttcgtgcaacctggggtcgctgaac
atcgccaagacgatggactcgccggacttcgcacagacgatcgaggtggcgatccgcgcg
ttgacggcggtgagcgaccaaacccatatcaagtcggtgccctcaatcgagcagggcaac
aacgattctcacgcgatcgggctaggacagatgaacctgcacggctacctggcccgggaa
cgcatcttctacggatccgaagaaggcatcgacttcaccaacatctacttctatatcgtg
ctgtatcacgcactgcgggcatccaaccgcatcgcgatcgaacgtggcacgcacttcaag
ggtttcgagcggtccaagtacgcgtccggggaattcttcgacaagtacaccgaccagatt
tgggagccgaagacccagaaggtacgccagctgttcgccgacgctggcatccgcatccca
acgcaggatgattggcgtcggctcaaggaatcggtgcaagcgcacggcatctacaaccag
aacctgcaggcggtgccgccgaccgggtcgatttcctacatcaaccattcgacgtcgtcg
attcacccgatcgtgtcgaaggtcgagatccgcaaggaaggcaagatcgggcgggtctac
tacccggcgccgtatatgaccaacgacaacctggagtactacgaagacgcctacgagatc
ggttacgagaagatcatcgacacctacgcggcggccacccagcatgtggatcaagggctt
tcgctgacgttgttcttcaaagacaccgccaccacccgcgacgtgaacaaggcgcagatt
tacgcctggcgcaaggggatcaagacgctgtactacatccggctgcggcagatggcgttg
gagggcaccgaggtcgagggttgcgtgtcctgcatgctgtag

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