| Entry |
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| Symbol |
RET
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| Name |
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform X1
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| KO |
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| Organism |
mdt Myotis daubentonii (Daubenton's bat)
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| Pathway |
| mdt05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:mdt00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
132214757 (RET)
04020 Calcium signaling pathway
132214757 (RET)
04151 PI3K-Akt signaling pathway
132214757 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132214757 (RET)
05230 Central carbon metabolism in cancer
132214757 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
132214757 (RET)
05223 Non-small cell lung cancer
132214757 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:mdt01001]
132214757 (RET)
Enzymes [BR:mdt01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
132214757 (RET)
Protein kinases [BR:mdt01001]
Receptor tyrosine kinases (RTK)
RET family
132214757 (RET)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
13:complement(10534085..10584245)
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| AA seq |
1114 aa
MAKATAGTAGLRWLLLLLPLLSEAPLGLYFSRDAYWEKLYVDQPAGTPLLYVHALRDAPD
EVPSFRLGQHLYGAYRKRLHENDWIRIQEDTGLLYLNCSLNHSSWEKLNIRNGGFPQLTV
YLQVFLYPTPLREGECQWPGCARIYFSFINASFPACGSLKPRELCFPDREPSFRIRENRP
PGTFHQFRQLAVQFLCPNISMAYRLLGGENLPFRCASDSLEVSTRRPLDRERQEKYELVA
ACTVRMGARKEEEVMVPFPVTVYDEDDSAPSFLDGVDTASAVVEFKRKKGTVVATLHVFD
PDVVPASGELLRRYTSTLLPGDAWALQTFRVEHSPNETLVQADGSFIRATVHDYRLVLNR
SLPISESRTLQLAVLVNDSSFQGPGEGTLLLHFNVSVLPVSLRLPSAYSFTVSRRAHLFA
QVGKVSVENGQEFTGIHLRYELQLSSANCSALGVVTSAEDASGTLFVNDTEALRRPECTQ
LQYMVVATDQPTGSQAHGPLLVTVEGTYVAEEPGCPLSCAVSKRRPKCEECGGLGSLTGR
CEWRQGDGKGISRNFSTCSPSIKTCPDSHCDAVESSNPHICPQDCLRGSIIGGHEPGERW
GIKAGFGTCSCFPEKRRCFCEPEDSQDPLCDELCRTVIAAAVLFSFIISVLLSTFCIHRY
HKNAHKAPIASAEMTVHRPAQAFPISYSSSSARRPSLDSMENQVSVDAFKIPEDPKWEFP
RKNLVLGKTLGEGEFGKVVEATAFRLKGKAGYTTVAVKMLKENASPNELRDLLSEFNLLK
QVNHPNVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYVGSGGSRNSSYLDN
PDERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVY
EEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL
FNLLKTGYRMERPDNCSEEMYSLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAA
STPSDSLLYDDGLSEEEMPLVDCNNAPLPRTLPSTWIENKLYGMSDPNWPEESPVPLTRA
DGTSTGCPRYANDSVYANWMVSPSAAQLTDSFDS |
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| NT seq |
3345 nt +upstreamnt +downstreamnt
atggcgaaggcaacggccggcaccgcggggctgcgatggctgctgctgctgctgccgctg
ctcagcgaagccccgctgggactctacttctccagggacgcttactgggagaagctgtac
gtggaccaaccggccgggacgcccctgctctacgtgcacgccctgcgcgacgcccccgat
gaggtgcccagcttccgcctcggccagcacctctacggcgcctaccgcaagcggctgcac
gagaatgactggattcgcatccaggaggacacgggccttctctacctgaactgcagcctg
aaccacagctcctgggagaagctcaacatacgcaatggcggcttcccccagctcaccgtc
tacctccaggtcttcctgtatcccacacccctgcgtgagggcgaatgccagtggccaggc
tgtgcccgcatctacttttccttcatcaacgcctccttcccggcgtgcggctccctcaaa
ccccgggagctctgcttccccgacagggagccctcctttcgaattcgggagaaccggcct
ccaggcaccttccaccagtttcgccagctggcagtgcagttcctctgccccaacatcagc
atggcctacaggctcctgggaggtgagaacctgcccttccgctgcgcctccgacagccta
gaggtgagcacacggcggcccctggaccgcgagcgccaagagaagtatgagctggtggcg
gcctgcacagtgcgcatgggcgcacgcaaggaggaggaggtgatggtgccgttccccgtg
actgtgtacgacgaggacgactcggcgccctcctttctggacggcgttgacaccgccagt
gccgtcgtggagttcaagcggaagaagggcactgtggtggccaccctgcatgtcttcgat
ccggatgtggtgccagcatccggggagctcctgaggcggtacacaagcacgctgctcccc
ggagatgcctgggccctccagaccttccgtgtggagcactcacccaatgagaccttggtc
caggccgacggcagcttcattcgggcaacggtgcatgactacaggctggtcctcaaccgc
agcctccccatctcggagagccgcaccctgcagctggctgtgctggtcaatgactccagc
ttccagggccctggggagggcaccctcctcctccacttcaacgtgtcggtgctgccggtc
agcctgcgcctgcccagtgcctactccttcaccgtgagcaggcgggcccacctcttcgcc
caggttgggaaagtctccgtggagaacggccaggagttcacgggcatccacctgcggtac
gagctgcagctctccagcgccaactgcagcgccctgggagtggtcacctcggccgaggac
gcctcggggaccctgttcgtgaatgacacggaggccctgcggcggcccgagtgcacccag
ctccagtacatggtggtggccaccgaccagccaaccggcagccaggcccatggcccactg
ctcgtcaccgtggaggggacgtacgtggctgaggagccaggctgcccactgtcctgcgcc
gtcagcaagaggcggcccaagtgtgaggagtgcggtggcctgggctctctgacaggcagg
tgcgagtggagacagggagacggcaaagggatctccaggaacttctccacctgctccccc
agcatcaagacctgccccgacagccactgtgatgccgtggagagcagcaacccccacatc
tgcccccaggactgcctccggggcagcatcattggggggcatgagccaggggagcgctgg
gggattaaagccggctttgggacctgcagctgcttccctgagaagaggaggtgcttctgt
gagccggaggacagccaggacccgctgtgcgacgagctgtgccgcacggtgatcgcggcg
gccgtgctcttctccttcatcatctccgtgctgctgtccaccttctgcatccaccgctac
cacaagaacgcccacaaggcgcccatcgcctcggccgagatgactgtccaccggccggcc
caggccttccccatcagctactcctcctccagtgcccggcggccctcgctggactccatg
gagaaccaggtctctgtggacgccttcaagatcccggaggacccaaagtgggagttcccg
cggaagaatttggttcttggaaaaactctgggagaaggcgaatttggaaaagtggtcgag
gcaacagccttccggctgaaaggcaaagctgggtacacgactgtggccgtgaagatgctg
aaagagaacgcctccccaaatgagctgcgggacctactgtcagaattcaacctcctgaag
caggtcaaccaccccaacgtcatcaagctgtatggggcctgcagccaggacgggccgctt
ctcctcatcgtggaatatgccaagtacggctcccttcggggcttcctgcgagagagccgc
aaggtggggcccggctacgttggcagcggaggcagccgcaactccagctacctggacaac
ccggacgagcgggccctgaccatgggtgacctcatctccttcgcctggcagatctcacgg
gggatgcgatacctggccgagatgaagctcgtccatcgggacttagcagccagaaacgtc
cttgtagccgaggggcggaagatgaagatttcggactttggtctgtcccgggatgtgtat
gaagaggattcctatgtgaagaggagcaagggccggattccagtcaaatggatggcaatt
gagtccctgtttgatcatatctacaccacccagagtgatgtgtggtcctttggtgtcctg
ctgtgggagattgtgaccttggggggcaacccctaccctgggattcctcctgagcggctc
ttcaaccttctgaagacgggctaccggatggagaggcctgacaactgcagcgaggagatg
tatagcctgatgctgcagtgctggaagcaggagccagacaagaggccggtgtttgccgac
atcagcaaagacctggagaagatgatggttaagagaagggactacttggatctggccgcg
tccaccccgtccgactccctgctttacgatgacggcctctcggaagaggagatgcccctg
gtggactgtaataatgctcccctccctcgaaccctcccctccacgtggattgaaaacaaa
ctctatggcatgtcagacccgaactggcctgaggagagtcctgtaccactcacgagagcc
gatggcactagcactgggtgtccacgctatgccaatgatagtgtatatgctaactggatg
gtttcaccctcagcggcacaattaacggactcgtttgatagttaa |
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