Megasphaera stantonii: DKB62_11715
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Entry
DKB62_11715 CDS
T05599
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
meg
Megasphaera stantonii
Pathway
meg00290
Valine, leucine and isoleucine biosynthesis
meg00660
C5-Branched dibasic acid metabolism
meg01100
Metabolic pathways
meg01110
Biosynthesis of secondary metabolites
meg01210
2-Oxocarboxylic acid metabolism
meg01230
Biosynthesis of amino acids
Module
meg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
meg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
DKB62_11715 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DKB62_11715 (leuC)
Enzymes [BR:
meg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
DKB62_11715 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
DKB62_11715 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AXL22176
UniProt:
A0A346B233
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Position
2481360..2482619
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AA seq
419 aa
AA seq
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MGMTMTQKILAKHAGLPSVKAGDLITCKLDMVLANDITAPPAIAEFNKIGRPVFDKDKIA
LVPDHFTPNKDIKSAGLAKIVRDFAREHEITHYFEVGRVGIEHVLLPEQGIVGPGMLTIG
ADSHTCTYGALGGFATGVGSTDLGVAMATGEAWFKVPEAINVHLTGQKPDDITGKDVMLT
LIGMIGVDGALYKSLEFTGEGVAALTMTDRLTIANMAIEAGAKNGIFPVDEQTIAYEKGR
INYEYDVVTADEDAEYCRIVDINLSELKPVVAFPHLPGNTKVIGTFGDIAIDQVVIGSCT
NGRLEDLEIAASILKGRKVHPRVRCIVIPGSQQVYMDAMKAGYIETFITAGCAVSTPTCG
PCLGGYMGILAAGEKCVSTTNRNFRGRMGHVDSEVYLAGPQVAAASAILGKIAAPKEVQ
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgacgatgacgcagaagatactggcaaagcacgccggccttccttctgtcaaa
gcaggagatttgattacgtgcaagttagatatggtactggccaacgacattacggcgccg
ccggccatcgccgaattcaataaaatcggccggcccgttttcgacaaggataaaatcgcc
ttggtaccggaccactttacgccgaacaaggacattaaatcggcaggtttagcgaaaatc
gtccgcgattttgccagggaacacgaaattacccattactttgaagtgggccgcgtcggc
atcgagcacgtcctcttgcccgaacagggcatcgtagggccgggcatgctgaccataggc
gctgactcccatacctgtacgtacggcgcattaggcggctttgccaccggcgtcggctcg
accgacttgggcgtggccatggcgacgggcgaagcgtggttcaaggtgcccgaagccatc
aacgtccatctgacgggacaaaagcccgatgatattacgggcaaggacgtcatgctgacc
ctcatcggcatgatcggcgtcgacggcgcgctgtacaaatcgctggaattcaccggcgaa
ggtgtggcggccctcaccatgaccgaccgcctgaccattgccaacatggctattgaagcc
ggtgcgaagaacgggattttccccgtcgacgaacagacgatagcctacgaaaaaggccgc
atcaactacgaatacgacgtcgtcacagccgatgaagacgccgaatactgccggatcgtc
gacatcaacctgtccgaactgaagcctgtcgtagccttcccgcatctgccgggcaatacg
aaggtcatcgggaccttcggcgacatcgctatcgatcaggtcgtcatcggctcctgcacg
aacggccgtctggaagatttggaaatcgccgcgtcgatcctgaagggacgcaaggttcat
ccccgcgtccgctgcatcgtcatccccggcagccagcaggtctacatggacgccatgaag
gccggctatatcgaaaccttcattacggcgggctgcgccgtgtctacgccgacgtgcggc
ccctgcctgggcggctacatgggcatcctcgccgccggcgaaaaatgcgtgtccacgacg
aaccgcaatttccgcggccgcatgggccacgtcgacagcgaagtatatctggcagggccg
caggtcgccgctgccagcgcaattctcggcaagatagccgcaccgaaggaggttcagtaa
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