KEGG   PATHWAY: met00540Help
Entry
met00540                    Pathway                                

Name
Lipopolysaccharide biosynthesis - Methylobacterium sp. 4-46
Class
Metabolism; Glycan biosynthesis and metabolism
BRITE hierarchy
Pathway map
met00540  Lipopolysaccharide biosynthesis
met00540

Ortholog table
Other DBs
BSID: 66385
GO: 0009103
Organism
Methylobacterium sp. 4-46 [GN:met]
Gene
M446_0643  acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase [KO:K00677] [EC:2.3.1.129]
M446_6696  UDP-3-0-acyl N-acetylglucosamine deacetylase [KO:K02535] [EC:3.5.1.108]
M446_3203  UDP-3-0-acyl N-acetylglucosamine deacetylase [KO:K02535] [EC:3.5.1.108]
M446_0641  UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase [KO:K02536] [EC:2.3.1.191]
M446_0645  lipid-A-disaccharide synthase [KO:K00748] [EC:2.4.1.182]
M446_6829  tetraacyldisaccharide 4'-kinase [KO:K00912] [EC:2.7.1.130]
M446_1995  KpsF/GutQ family protein [KO:K06041] [EC:5.3.1.13]
M446_4766  2-dehydro-3-deoxyphosphooctonate aldolase [KO:K01627] [EC:2.5.1.55]
M446_1619  3-deoxy-D-manno-octulosonate cytidylyltransferase [KO:K00979] [EC:2.7.7.38]
M446_6828  Three-deoxy-D-manno-octulosonic-acid transferase domain protein [KO:K02527] [EC:2.4.99.15 2.4.99.14 2.4.99.13 2.4.99.12]
M446_4861  lipid A biosynthesis acyltransferase [KO:K02517] [EC:2.3.1.241]
M446_6086  glycosyl transferase group 1 [KO:K02844] [EC:2.4.1.-]
Compound
C00043  UDP-N-acetyl-alpha-D-glucosamine
C00199  D-Ribulose 5-phosphate
C00229  Acyl-carrier protein
C01112  D-Arabinose 5-phosphate
C01187  3-Deoxy-D-manno-octulosonate
C04121  CMP-3-deoxy-D-manno-octulosonate
C04478  3-Deoxy-D-manno-octulosonate 8-phosphate
C04652  UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine
C04738  UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine
C04824  Lipid X
C04919  2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
C04932  Lipid A disaccharide
C05223  Dodecanoyl-[acyl-carrier protein]
C05382  Sedoheptulose 7-phosphate
C05761  Tetradecanoyl-[acp]
C06022  UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine
C06024  3-Deoxy-D-manno-octulosonyl-lipid IV(A)
C06025  Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)
C06026  Di[3-deoxy-D-manno-octulosonyl]-lipid A
C06251  Lauroyl-KDO2-lipid IV(A)
C06397  ADP-D-glycero-beta-D-manno-heptose
C06398  ADP-L-glycero-beta-D-manno-heptose
C07836  D-glycero-beta-D-manno-Heptose 7-phosphate
C07838  D-glycero-beta-D-manno-Heptose 1-phosphate
C11472  D-glycero-beta-D-manno-Heptose 1,7-bisphosphate
C19877  4-O-Phospho-alpha-Kdo-(2->6)-lipid IVA
C19878  D-glycero-alpha-D-manno-Heptose 7-phosphate
C19879  D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate
C19880  D-glycero-alpha-D-manno-Heptose 1-phosphate
C19881  GDP-D-glycero-alpha-D-manno-heptose
Reference
PMID:9791168
  Authors
Heinrichs DE, Yethon JA, Whitfield C.
  Title
Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica.
  Journal
Mol Microbiol 30:221-32 (1998)
DOI:10.1046/j.1365-2958.1998.01063.x
Reference
  Authors
Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P.
  Title
Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli.
  Journal
J Bacteriol 184:363-9 (2002)
DOI:10.1128/JB.184.2.363-369.2002
Reference
PMID:9587193
  Authors
Wyckoff TJ, Raetz CR, Jackman JE.
  Title
Antibacterial and anti-inflammatory agents that target endotoxin.
  Journal
Trends Microbiol 6:154-9 (1998)
DOI:10.1016/S0966-842X(98)01230-X
Reference
PMID:9765561
  Authors
Shibayama K, Ohsuka S, Tanaka T, Arakawa Y, Ohta M.
  Title
Conserved structural regions involved in the catalytic mechanism of Escherichia coli K-12 WaaO (RfaI).
  Journal
J Bacteriol 180:5313-8 (1998)
KO pathway
ko00540   
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