Mycobacterium florentinum: MFLOJ_47450
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Entry
MFLOJ_47450 CDS
T06524
Name
(GenBank) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
KO
K16045
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mfj
Mycobacterium florentinum
Pathway
mfj00984
Steroid degradation
mfj01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mfj00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
MFLOJ_47450
Enzymes [BR:
mfj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
MFLOJ_47450
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
MFLOJ_47450
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Gene cluster
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_10
RmlD_sub_bind
NAD_binding_4
Polysacc_synt_2
KR
NmrA
adh_short
NAD_binding_2
Motif
Other DBs
NCBI-ProteinID:
BBX80958
LinkDB
All DBs
Position
complement(4937422..4938546)
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AA seq
374 aa
AA seq
DB search
MLSGMGDAALTTELGRVLVTGGSGFVGANLVTTLLDRGYSVRSFDRAPSPLAPHSQLEVL
QGDITDKDVCAQAVAGIDTVFHTAAIIELLGGASVTDEYRQRSFAINVGGTENLAEAGRA
AGLQRFVYTSSNSVVMGGQTIAGGDETLPYTTRFNDLYTETKVVAERYVLSQNGVDGMLT
CAIRPSGIWGRGDQTMFRKLFESVIAGHVKVLIGRKSARLDNSYVHNLIHGFILAAQHLV
PGGTAPGQAYFINDDEPINMFEFARPVVEACGQPWPRIRVNGPVVRAAMTGWQRMHFRFG
IPAPLLEPLAVERLYLDNFFSVAKASRDLGYQPLFTTEKALTECLSYYVDMFGQMKRQAE
TAKAAAKRKPHSAQ
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgctgtccggcatgggtgatgcagcactgacaaccgaactgggccgcgtcctggtcacc
gggggctccggattcgtcggcgccaacctggtgaccaccttgctcgaccgcggatattcg
gtgcgttccttcgaccgcgcgccgtcgccgctcgccccgcactcacagctggaggtgctg
cagggcgacatcaccgacaaggacgtctgcgcgcaggcggtggccggcatcgacaccgtc
tttcacaccgcggcgatcatcgagctgctgggtggggcgtcggtgaccgacgaataccgt
cagcgcagctttgcgatcaacgtcggcggcaccgagaatctggcggaggccgggcgcgcg
gccggcctgcagcgattcgtctacacgtcatccaacagcgtggtgatgggcggccagacc
atcgccggcggcgacgaaacgctgccctacaccactagattcaacgacctctacaccgag
accaaggtggtcgccgagcgatacgtgttgtcccagaacggcgttgacgggatgctgacg
tgtgcgatccggcccagcggcatctggggccgcggcgaccagacgatgttccggaagctg
ttcgagagcgtgatcgccggccacgtcaaggttctgatcggccgcaagtcggcccggctg
gataactcctacgtgcacaacctgattcacggcttcatcctggccgcccagcatctggtg
cccggcggcaccgcgccgggtcaggcgtacttcatcaacgacgacgagccgatcaacatg
ttcgagttcgcgcggccggtggtggaggcctgcgggcagccctggccgcggatccgggtc
aacgggcccgtcgtgcgggcggccatgaccggctggcagcggatgcacttccggttcgga
attcccgcgccgctgctggagccgctggcggtcgagcggctgtacctggacaacttcttc
tcggtcgccaaggcctcccgcgacctcggttaccagccgctgttcaccaccgagaaggcg
ttaaccgagtgcctgtcctactacgtggacatgttcggccagatgaagaggcaggccgag
acggccaaggccgccgccaagcgcaaaccgcactctgcccaatag
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