Manis javanica (Malayan pangolin): 108387253
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Entry
108387253 CDS
T06054
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04010
MAPK signaling pathway
mjv04020
Calcium signaling pathway
mjv04022
cGMP-PKG signaling pathway
mjv04024
cAMP signaling pathway
mjv04260
Cardiac muscle contraction
mjv04261
Adrenergic signaling in cardiomyocytes
mjv04270
Vascular smooth muscle contraction
mjv04713
Circadian entrainment
mjv04720
Long-term potentiation
mjv04723
Retrograde endocannabinoid signaling
mjv04724
Glutamatergic synapse
mjv04725
Cholinergic synapse
mjv04726
Serotonergic synapse
mjv04727
GABAergic synapse
mjv04728
Dopaminergic synapse
mjv04742
Taste transduction
mjv04911
Insulin secretion
mjv04912
GnRH signaling pathway
mjv04921
Oxytocin signaling pathway
mjv04924
Renin secretion
mjv04925
Aldosterone synthesis and secretion
mjv04927
Cortisol synthesis and secretion
mjv04929
GnRH secretion
mjv04930
Type II diabetes mellitus
mjv04934
Cushing syndrome
mjv04935
Growth hormone synthesis, secretion and action
mjv05010
Alzheimer disease
mjv05020
Prion disease
mjv05022
Pathways of neurodegeneration - multiple diseases
mjv05031
Amphetamine addiction
mjv05207
Chemical carcinogenesis - receptor activation
mjv05410
Hypertrophic cardiomyopathy
mjv05412
Arrhythmogenic right ventricular cardiomyopathy
mjv05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108387253 (CACNA1C)
04020 Calcium signaling pathway
108387253 (CACNA1C)
04024 cAMP signaling pathway
108387253 (CACNA1C)
04022 cGMP-PKG signaling pathway
108387253 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
108387253 (CACNA1C)
04929 GnRH secretion
108387253 (CACNA1C)
04912 GnRH signaling pathway
108387253 (CACNA1C)
04921 Oxytocin signaling pathway
108387253 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
108387253 (CACNA1C)
04924 Renin secretion
108387253 (CACNA1C)
04925 Aldosterone synthesis and secretion
108387253 (CACNA1C)
04927 Cortisol synthesis and secretion
108387253 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
108387253 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
108387253 (CACNA1C)
04270 Vascular smooth muscle contraction
108387253 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
108387253 (CACNA1C)
04727 GABAergic synapse
108387253 (CACNA1C)
04725 Cholinergic synapse
108387253 (CACNA1C)
04728 Dopaminergic synapse
108387253 (CACNA1C)
04726 Serotonergic synapse
108387253 (CACNA1C)
04720 Long-term potentiation
108387253 (CACNA1C)
04723 Retrograde endocannabinoid signaling
108387253 (CACNA1C)
09157 Sensory system
04742 Taste transduction
108387253 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
108387253 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
108387253 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
108387253 (CACNA1C)
05020 Prion disease
108387253 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
108387253 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
108387253 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
108387253 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
108387253 (CACNA1C)
05414 Dilated cardiomyopathy
108387253 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
108387253 (CACNA1C)
04934 Cushing syndrome
108387253 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mjv04040
]
108387253 (CACNA1C)
Ion channels [BR:
mjv04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
108387253 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Motif
Other DBs
NCBI-GeneID:
108387253
NCBI-ProteinID:
XP_036870779
LinkDB
All DBs
Position
Unknown
AA seq
2198 aa
AA seq
DB search
MLRAFVQPATPAYQPLPSHSPAETELTFKGTVVHEAQLNCFYIPPGGSNYGSPRPAHANM
NANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPK
KQGSTPATRPPRALLCLTLRNPLRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPED
DSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSA
ILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLH
IALLVLFVIIIYAIIGLELFMGKMHKTCYSQEGIADVPAEDDPSPCALETGHGRQCQNGT
VCRPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLII
IGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIEPE
NEDEGAEEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWN
RFCRRKCRAAVKSNIFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAE
MLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKI
TRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFD
NFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLA
IAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVVEKPAVEETKEEKIELKSIT
ADGESPRTTKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEK
AVPMPEASAFFIFSPSNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN
HILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA
INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQL
FKGKLYICSDSSKQTEAECKGNYITYKDGEVDQPIVQARSWENSKFDFDNVLAAMMALFT
VSTFEGWPELLYRSIDSHTEDKGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQ
EQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLIL
LNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMVLKLIAFKPKGHFSDPWNVFDFLI
VIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSR
ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF
GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTE
GETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWA
EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATL
FALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATF
LIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDLGPEIRRAISGDLTAEEELDKA
MKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHISKAGDSQGTTES
PSHERLVDSTFTPSSYSSTGSNANINNANNTALGRLPQPTGPPSAVSTMEGHWPPLSPAV
QGPEAAWKLSSKRCHSRESQMAMVCKEAVSQDEPCDMRMNEDTEYGSEPSLTCTDLFSYQ
DDENRQLTPPEEDERDTRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPL
HLVHHQALAVAGLSPLLQRSHSPTTFLRPCTTPPATPSGRGWPPQPIPTLRLEGAESSEK
LNSSFPSIHCGSWSGEPMHCDRGSGAIRRARPVSLTVPSQAAAQGRQFHGSASSLVEAVL
ISEGLGQFAQDPKFIEVTTQELADACNMTIEEMENAADNILSGGAQQSPNGALLPFVNCR
DPGQDRAGGGEHESCAAPLERGTSEEGAQDSRAFAGSL
NT seq
6597 nt
NT seq
+upstream
nt +downstream
nt
atgcttcgagccttcgtgcagcccgccacgcctgcctaccagccgcttcctagtcactca
cctgccgaaacagagttgacgtttaagggcactgtggtgcatgaagcccaactcaactgt
ttctacatccctcctggaggttccaactatgggagcccgcgcccagctcacgccaacatg
aatgccaacgcagctgcggggctcgcacctgagcacatccccacgccgggggcggctctg
tcctggcaggcagccattgatgcagcccggcaggccaagctgatgggcagcgctggcaat
gcgaccatctccacagttagctccacgcagcggaaacggcagcagtatgggaagcccaag
aagcagggcagcacccccgccacgcgcccgccccgcgccctgctctgcctgaccctgcgg
aaccccctccggcgggcgtgcatcagcatcgtggagtggaaaccatttgaaataattatt
ttactgactatttttgccaattgtgtggccttagcgatctatattcccttcccagaagat
gactccaacgctactaattccaacctggaacgagtggaatatctctttctcataattttt
actgtggaagcatttttaaaagtaatagcctatggacttctctttcaccccaatgcttac
ctccgcaatggctggaacttactagattttataattgtggttgtagggctttttagtgca
attttagaacaggcaaccaaagccgacggggccaatgccctaggagggaaaggggctgga
ttcgacgtgaaggcactgagggccttccgtgtgctgcgccccttgcggctggtgtctgga
gtcccgagtctccaggtggtcctgaactccatcatcaaggccatggtacccctgctgcat
atcgcccttctcgtgctgtttgtcatcatcatctacgccatcatcggcctggagcttttc
atggggaagatgcacaagacctgctacagccaggagggcatagcagatgtcccagcggaa
gacgacccttcaccgtgcgcgctggagaccggccacgggcggcagtgccagaacggcacg
gtgtgcaggcccgggtgggacgggcccaagcatggcatcaccaacttcgacaactttgcc
ttcgccatgctgaccgtgttccagtgcatcaccatggagggctggaccgacgtgctgtac
tgggtcaatgatgccgtaggaagggactggccctggatctattttgttacactaatcatc
atagggtcattttttgtacttaacttggttctcggtgttcttagcggggagttttccaaa
gagagggagaaggccaaggcgcggggagatttccagaagctgcgagagaagcagcagctg
gaggaggacctcaaaggctacctggactggatcactcaggcagaggacatcgagcctgag
aatgaggatgagggcgcggaggaggagaagccgcgcaacatgagcatgcccacgagtgag
acggagtctgtcaacaccgaaaacgtggctggaggggacatcgagggagaaaactgcggg
gccaggctggcccaccggatctccaaatcgaagttcagccgctactggcgccggtggaac
cgattctgcaggagaaagtgccgcgcagcagttaagtccaacatcttctactggcttgtg
atcttcctggtgttcctcaacacactcaccatcgcctcggagcactacaaccagccccac
tggctcacggaggtccaagacacggccaacaaggccctgctggcccttttcacggcggag
atgctgctgaagatgtacagcctgggcctgcaggcctacttcgtatccctgttcaaccgc
tttgactgcttcattgtgtgtggcggcatcctggagaccatcctggtggagaccaagatc
atgtctcccttgggcatctctgtgctgcggtgcgtccggcttctgaggatattcaagatc
acaaggtactggaactccttaagcaacctggtggcatccttgctgaattccgttcgttcc
attgcctctctgctgctgctcctcttcctcttcatcatcatcttctccctcctggggatg
cagctctttggaggaaagttcaactttgatgagatgcagacccggaggagcacatttgat
aactttccgcagtccctcctcaccgtgtttcagatcctgaccggggaggactggaattcg
gtgatgtatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgt
atttacttcatcatcctcttcatctgtggaaattatatcctactgaatgtgttcttggcc
attgctgtggacaatctggctgatgctgagagcctcacatccgctcagaaggaggaagaa
gaagagaaggagaggaagaagctggccaggactgccagcccagaaaagaagcaagaggtg
gtagagaagccagcagtggaggagaccaaggaggagaagattgagctgaagtccattaca
gctgatggagagtccccacgcaccaccaagatcaacatggatgacctccagcccaatgaa
aatgaggataagagtccttaccccaacccagaaactacaggagaagaggatgaggaggag
cccgaaatgcctgtgggcccccgcccacgaccactttctgagctgcaccttaaggagaag
gcagtgcccatgccagaagccagtgcatttttcatctttagccccagcaacaggttccgc
ctccagtgccaccgcattgtcaatgacacgatcttcaccaacctgatcctcttcttcatt
ctgctcagcagcatctccctggctgctgaggaccctgtccagcacacctccttcaggaac
catattctgttttattttgatattgtttttactaccattttcaccattgaaattgctctg
aagatgactgcttatggtgccttcctgcacaagggctctttctgccgtaactacttcaac
atcctggacctgctggtggtcagtgtgtccctcatctccttcggcatccagtccagcgcc
atcaatgtcgtgaagatcctgcgggttctgcgagtgctcaggcccctgagggccatcaac
agggccaagggactaaagcacgtggtacagtgtgtgttcgtcgctatccggaccattggg
aacatcgtgattgtcaccactctgctccagttcatgttcgcctgcattggggtccagctc
ttcaagggaaagctctacatctgttcagatagctccaaacagactgaggcggaatgcaag
ggcaactacatcacatacaaggatggggaggttgaccaacccatcgtccaggcgcgcagc
tgggagaacagcaagtttgactttgacaatgttctggcagccatgatggccctcttcact
gtctccacatttgaggggtggccagagctgctgtaccgctccattgactcccacacagag
gacaagggccccatctacaaccaccgtgtggagatctccatcttcttcatcatctacatc
atcatcatcgccttcttcatgatgaacatcttcgtgggcttcgtcatcgtcaccttccaa
gagcagggcgagcaggagtacaagaactgcgagctggacaagaaccagcgacagtgtgtg
gaatatgccctcaaggcccggcctctgcggagatacatccccaagaaccagcaccagtac
aaagtgtggtatgtggtcaactccacctactttgagtacctgatgtttgtcctcatcctt
ctcaacaccatctgcttagccatgcagcactatggccagagctgcctgttcaaaatcgcc
atgaacatcctcaacatgctcttcactggtctcttcactgtggagatggtcctgaagctc
attgccttcaaacccaagggacactttagtgatccctggaatgtctttgacttcctcatc
gtaattggcagcataattgacgtcattctcagtgaaactaatcactatttctgtgatgca
tggaatacatttgacgccctgattgttgtgggtagcattgttgatatagcaatcaccgag
gtaaacccagctgaacatacccaatgctctccctttatgaacgcagaggagaactcccgc
atctccatcaccttcttccgcctcttccgggtcatgcgcctagtcaagctgctgagccgt
ggggagggcatccggaccctgctgtggaccttcatcaagtccttccaggcgctgccctac
gtggccctcctcatagtgatgctgttcttcatctatgccgtgatcggcatgcaggtgttt
gggaaaattgccctgaatgataccacagagatcaaccggaacaacaattttcagaccttc
ccccaagctgtactactactcttcaggtgtgccacaggggaggcatggcaggacatcatg
ctggcctgcatgccagggaagaagtgtgccccagagtcagagcccagcaacagcacagaa
ggggaaacgccctgtggcagcagctttgccgtcttctacttcatcagcttctacatgctc
tgtgccttcctgatcatcaacctctttgtggctgtcatcatggacaactttgactacctg
acaagggactggtcaatccttggtccccaccatctggacgaatttaaaagaatttgggca
gagtatgaccctgaagccaagggtcgtatcaaacacctagatgtagtgaccttgctccgg
cggattcagcccccactgggtttcgggaagctgtgccctcaccgtgtggcttgcaaacgc
ctggtctccatgaacatgcctctgaacagcgacgggacagttatgttcaacgccaccctg
tttgccctcgtccggacagccctgaggatcaaaacagaagggaacctggaacaagccaat
gaggagctgcgggccataatcaagaagatctggaaacggaccagcatgaagctgctggac
caggtggtgccccctgcaggcgatgatgaggtcacggttggcaagttttacgctacattc
ctgatccaagagtacttccggaaattcaagaagcgcaaagagcagggccttgtgggcaag
ccctcccagaggaatgcactgtccctccaggccggcttgcgcacactgcatgacctcggg
cctgagatccggcgggccatctccggagatctgacagccgaggaggagctggacaaggcc
atgaaggaggctgtgtctgctgcctctgaagatgacatcttcaggagggccggtggcctg
ttcggcaaccatgtcagctactaccaaagtgacggccggagcgccttcccccagaccttt
accacccagcgcccgctgcacatcagcaaggcaggcgacagccagggcaccaccgagtcg
ccgtcccacgagaggctggtggactccaccttcacgcccagcagctactcctccaccggc
tccaacgccaacatcaacaatgccaacaacacagcactgggccgcctcccccagcccact
ggcccccctagtgcagtcagcaccatggagggccattggcctcccttgtctcctgctgtc
caggggccggaggcagcatggaagctcagctctaagaggtgtcactcccgggagagccag
atggccatggtgtgtaaggaggcggtctctcaggacgagccctgtgacatgaggatgaat
gaggacacagagtatggcagcgagcccagcctgacctgcacagacctgttctcctaccag
gatgatgaaaatcgacaattgacaccccctgaggaggatgagagggacacccggcagtct
ccgaagaggggcttcctccgctccgcctccctcggtcgaagggcctccttccacctggaa
tgtctgaagcgacagaagaatcaagggggagacatctctcagaagacagtcctgcccctg
cacctggtccatcatcaggcattggcagtggcaggcctgagccccctcctccagagaagc
cattcacctaccacgttcctccggccgtgcaccaccccgcctgccacgcccagtggccga
ggctggcccccgcagcccatcccgaccctgcggctggagggggccgagtccagcgaaaaa
ctcaacagcagcttcccgtccatccactgtggctcctggtctggggaacccatgcactgc
gataggggcagtggcgccatccgaagagcccggcctgtgtccctcaccgtgcccagccag
gccgcggcccagggcaggcagttccacggcagcgccagcagcctggtggaagcggtcttg
atttcagaaggactggggcagtttgctcaagatcccaagtttatcgaggtcacaacccag
gagctggcagacgcgtgcaacatgacaatcgaggagatggagaacgctgctgacaacatc
ctcagtgggggcgcccagcagagccccaacggcgccctgctcccttttgttaactgcagg
gacccggggcaggacagagcagggggcggggagcacgagagctgtgcggcccccctggag
cgtgggactagcgaggagggcgcgcaggacagcagagccttcgccggcagcctgtag
DBGET
integrated database retrieval system
