KEGG   Manis javanica (Malayan pangolin): 108391199
Entry
108391199         CDS       T06054                                 
Symbol
CAD
Name
(RefSeq) CAD protein isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv00220  Arginine biosynthesis
mjv00240  Pyrimidine metabolism
mjv00250  Alanine, aspartate and glutamate metabolism
mjv01100  Metabolic pathways
mjv01240  Biosynthesis of cofactors
Module
mjv_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    108391199 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    108391199 (CAD)
   00220 Arginine biosynthesis
    108391199 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mjv01002]
    108391199 (CAD)
Enzymes [BR:mjv01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     108391199 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     108391199 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     108391199 (CAD)
Peptidases and inhibitors [BR:mjv01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   108391199 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   108391199 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp Dala_Dala_lig_C MGS ATPgrasp_Ter Amidohydro_1 DHOase ATP-grasp_3 Peptidase_C26 GARS_A
Other DBs
NCBI-GeneID: 108391199
NCBI-ProteinID: XP_017506145
LinkDB
Position
Unknown
AA seq 2242 aa
MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPSDEVDEFGLSKWFESSGIHIAGLVVGECCPTPSHWSATRTLHEWLQQHGVPGLQGVD
TRELTKKLREQGSLLGKLIQDGTEPSTLPFLDPNARPLVPEVSIKALQVFNAHGTPRILA
LDCGLKYNQIRCLCQRGAEVTVVPWDHALNSQEYEGLFLSNGPGDPASYPNVVSTLSRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQSCLLVGSGRCCLTSQNHGFAVE
TDSLPAGWLPLFTNANDRSNEGIVHDSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA
IAGNPKGQTVRERLVERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTKTGVLARYGVRVLGTPVETIELTEDRRAFASRMAEIGEHVAPSEAAHSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEI
EYEVVRDVYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVERLYELTRIDRWFLHRM
KRIIAHAQLLEQHRGQPLSPVLLHQAKRLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIFELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ARDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LEQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLN
ETFSELRLDSMAQWMEHFETWPSHLPIVAHAERQSVAAILMVAQLTQRSVHICHVARKEE
ILLIKAAKARGLPVTCEVAPHHLFLSREDLERLGPGKGEVRPGLGSRQDVEALWENMAVI
DCFASDHAPHTLEEKGGPRPPPGFPGLETMLPLLLTAVSAGRLSLDDLLQRLHHNPRRIF
HLPPQEDTYVEVDLEHEWTVPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGAVPQLTPSAPATSEINTTPERPRRGIPGLPDGRFHLPPRIHRASD
PGLPAVFLRPGAGIPRGSRTWAEDPKEKPSRKAAEPELMGTLDGTCYPPPPVPRQASPQN
LGTPGLLHPQTSPLLHSLVGQHILSVKQFTKDQMSHLFNVAHMLRMMVQKERSLDILKGK
VMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVL
RHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKH
GRTVHSLACLLTQYRVSLRYVAPPSLRMPSNVWAFVASRGTKQEEFESIEEALPDTDVLY
MTRIQKERFGSAQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAY
FRQAENGMYMRMALLATVLGRF
NT seq 6729 nt   +upstreamnt  +downstreamnt
atggcggccctggtactggaggacgggtctgtcctgcggggccagccctttggggccgct
gtgtcgactgccggggaagtggtgtttcaaaccggcatggtcggctaccccgaagccctg
actgacccttcctacaaagcacagatcttagtgctgacatatcctctgatcggcaactat
ggcatccccagtgatgaagtggatgagttcggtctcagcaagtggtttgaatcttcaggg
attcatatagcaggactggtggtgggagagtgctgccccacacccagccattggagtgcc
acccgcaccctgcatgagtggctgcaacagcatggcgtacctggcctgcaaggagtggac
acccgggagctgactaagaagttgcgagagcaagggtctctgctgggaaagctgattcag
gatgggacagagccatcaaccctgccattcttggaccccaatgcccgccccctggtgccg
gaggtctccattaaggctctacaggtattcaatgcacatggtactccccggatccttgct
ttggactgtggcctcaagtataatcagattcggtgcctgtgccagcgtggggctgaggtc
actgtggtaccatgggaccatgcattaaacagccaggagtatgagggtctcttcctgagt
aatggccccggtgaccctgcctcctatcccaatgtggtatccacactaagtcgtgtctta
tctgagcctaatcctcgacctgtctttgggatctgtctgggacaccagctgttggcttta
gccattggggccaagacgtataagatgaggtatgggaaccgaggtcacaaccagtcgtgc
ttgctggtgggctctgggcgctgctgtctgacatcccagaaccatgggtttgctgtggaa
acagactcactgccagcaggctggcttcctctcttcactaatgccaatgatcgttccaat
gaaggcattgtacatgacagcctgccattcttcagtgtccagtttcacccagagcaccaa
gctggcccttcagatatggaacttctttttgacatctttctggaaactgtaaaagaagcc
atagctgggaaccctaagggccagacagtacgagagcggctggttgagcgcctctgtccc
cctgggattcccaccccaggctctgggcttccaccaccacgaaaggttctgatcctgggc
tcagggggcctgtccattggccaagctggagagtttgactactcaggctctcaggcgatc
aaggccctgaaggaggaaaacatccagacgttgctgatcaaccccaatattgccacggtg
cagacctcccaggggctggctgacaaggtctatttccttcccataacacctcactatgtc
acccaggtgatccgtaacgagcgcccagatggtgtgttactgacttttgggggccaaaca
gctctgaactgtggtgtggagctgaccaagactggagtcctagcccgctatggggtccgg
gtcctgggcacacctgtggagaccattgagctgaccgaggatcggcgtgccttcgcctct
aggatggcagagattggagagcacgtggcccccagtgaggcagcacattctcttgaacag
gcccaggcagctgccgagcgactggggtaccctgtgctggtacgtgcagcctttgcccta
ggcggcctaggctctggcttcgcctccaacagagaggagctctctgctcttgtggcccca
gcttttgcccacactagccaagtgctagtagacaagtccctgaaaggatggaaggagatt
gaatacgaggtggtgagagacgtctatggcaactgtgtcacagtatgtaacatggagaac
ttggacccactgggcatccacactggtgagtccatagtggtggctccaagccagacgctg
aatgacagggagtaccagctcctgcggcagacagccatcaaggtgacccagcaccttgga
atcgttggggagtgcaatgtacagtatgccttgaacccagagtctgagcagtattacatc
attgaagtgaatgccaggctctctcgcagctctgccctggccagtaaggccacaggctat
ccattagcctatgttgcagccaaactggctttgggcatccctctgcctgagctcagaaac
tcggtgacaggaggaacagcagcttttgaacccagcctggattattgtgtggtgaagatt
cctcgctgggacctcagcaagttcctccgtgtcagcacaaagatcgggagctgcatgaag
agcgttggtgaagtcatgggcattgggcgttcttttgaggaggccttccagaaggctctg
cgcatggtggatgagaactgtgtgggctttgatcacacagtaaagccagtcagcgatatg
gagctggagactccaacagataagcggatctttgtggtggcagctgctctgtgggctggc
tactcggtggagcgcctctatgaactcacgcgcatcgaccgctggttcctgcaccgaatg
aagcgaatcatagcacatgcccagctgctggagcaacaccgtggacagcctctgtctcca
gtcctgctgcaccaagccaagcgccttggtttctcagacaagcagatcgctcttgcagtt
ctgagcacagagctggctgttcgcaagctgcgtcaggaactggggatctgcccagcggtg
aaacagattgacacagttgcagctgagtggccagcccagacaaactatttgtacctgacg
tactggggcaccacccatgacctcaccttcagaacccctcatgtcctggtccttggctct
ggtgtctaccgtatcggctccagtgtggagtttgactggtgtgctgtgggctgcatccag
cagctccgaaagatggggtataagaccattatggtcaactacaacccggagacagtcagc
accgactatgacatgtgcgaccgactctactttgatgagatctcttttgaggtggtgatg
gacatctttgagctggagaaccctgagggtgtgatcctctccatgggcgggcagctaccc
aacaacatggccatggctttacatcggcagcagtgccgggtgctgggcacctctccagaa
gccatcgactcggctgagaaccgtttcaagttctcccgactccttgacaccattggtatc
agccagcctcagtggagggagctcagtgacctggagtctgctcgccagttctgccagact
gtggggtacccctgcgtggtgcgcccctcctatgtactgagtggcgctgctatgaacgtg
gcctacactgacggagacctggagcgctttctgagcagtgcagcagctgtctccaaggag
caccccgtggtcatctccaagttcatccaggaggccaaggagatcgatgtggatgctgtg
gcccgagatggtgtcgtggcagccatcgccatctctgagcatgtggagaatgcaggtgtg
cattcaggagatgccacgctggtaaccccaccacaggatatcactgctaaaaccctggag
cggatcaaagccatcgtgcatgccgtgggccaggagctgcaggtcactggacccttcaac
ctgcagctcattgccaaggacgaccagctgaaggttattgaatgcaacgtgcgtgtctct
cgctccttccccttcgtctccaagacacttggtgtggacctagtagccttggccacccgg
gtcatcatgggggaagaggtggagcctgtggggctcatgactggctctggagttgtggga
gtaaaggtaccccagttctccttctcccgcctggcgggtgctgacgtggtgttgggtgtg
gaaatgaccagtacaggggaagtggctggctttggggagagccgttgcgaggcctacctc
aaggccatgctgagcactggctttaagatccccaagaagaacatcttgctgaccattggc
agctataagaacaaaagtgagctgctcccaaccgtgcggctgctggagagtctgggctac
agcctctacgccagcctgggcaccgcagacttctacaccgagcatggcgtcaaggtaaca
gctgtggattggcacttcgaggaggccgtggatggtgagtgtccaccacagcgaagcatc
ttagagcagctggctgagaatcactttgagctagtgattaacctgtccatgcgtggggct
gggggccggcgtctctcctccttcgtcaccaagggctaccgcacacggcgcctggctgct
gacttctctgtgcccctcatcattgatatcaagtgcaccaaactgtttgtggaggcccta
ggccagatcgggccagccccccctttgaaggtgcatgttgactgcatgacttcccaaaag
cttgtgcggctgcctggattgattgacgtccatgttcacctgcgggaaccaggaggtact
cataaggaggactttgcctcaggcacagctgctgccctggcagggggtgtcaccatggtg
tgtgccatgcctaatacccggccccccatcatcgatgcccctgctctggccctcgcgcag
aagctggcagaggctggcgcccgctgtgactttgccttgttccttggagcttcatcggaa
aatgcagggaccctgggcactgtggctgggtctgctgcagggctgaagctctatctgaat
gagaccttctctgagctgcggctggacagcatggcccagtggatggagcactttgagacg
tggccgtcccacctccccattgtggcccatgccgagcggcagagtgtcgccgccatcctc
atggtggctcagctgacccagcgttcagtgcacatttgtcacgtggcgcggaaggaggag
atcctgctgataaaagctgcaaaggcacgggggctgccagtgacctgtgaggtggcaccc
caccatctgttcctgagccgcgaagacttggagcgcctggggcccgggaaaggggaggtc
cggcctggcctgggctcccgccaggatgtggaggccctgtgggagaacatggctgtcatt
gactgcttcgcctcagaccatgccccccacaccttggaggagaagggagggcccaggccc
ccgcctggcttcccaggactggagaccatgctgccattgcttctcacggctgtcagcgca
ggccggctcagtctggacgacctgctgcagcgcctgcaccacaatcctcggcgcatcttt
cacctgcccccccaggaggacacctatgtagaggtggatctggagcatgaatggacagtc
cccagccacatgcccttctccaaggcccactggacaccctttgaagggcagaaggtgaag
ggcactgtccggcgtgtggtcctacgaggggaggttgcttatatcgacgggcaggttctg
gtgcccccaggctatggacaggatgtacggaaatggcctcagggggctgttccccagctc
acgccctcagcccctgctaccagtgagataaacacgacacccgaaagaccccgccggggc
atcccagggcttcccgatggccgcttccacctgccaccccgaatccaccgagcttctgac
cctggtctcccagctgtgttcctccgcccgggagctgggatcccacggggcagcagaacg
tgggctgaggatccaaaggaaaagccctctcggaaggctgctgagccagagctgatggga
acccttgatggcacctgctatcctccaccaccagtgcctagacaggcgtcaccccagaac
ctggggacccctggcctgctgcacccccagacctcacccctgctgcactcattagtgggc
caacatatcctgtctgtcaagcagttcaccaaggatcagatgtctcacctcttcaatgtg
gcacacatgctgcgtatgatggtgcagaaggagcggagcctcgacatcctcaaggggaag
gtgatggcctccatgttctacgaggtgagcacaaggaccagcagctcctttgcagcagcc
atggcccggctcgggggtgcagtgctcagcttctcagaagccacgtcctccgtccagaag
ggtgaatctctggccgactctgtgcagaccatgagctgctatgccgatgttgttgtgctt
cggcacccccagcctggagcagtggagctggcagccaagcactgccggaggccagtgatc
aatgctggggatggggttggcgagcatcccactcaggccctgctggacatcttcaccatc
cgggaggagcttgggactgtcaatggcatgacgatcacaatggtgggggacctgaagcat
ggacgcacagtgcattccctggcctgtctgctcacccagtatcgtgtcagtctgcgctac
gtggccccgcccagcctgcgcatgccatccaatgtgtgggccttcgtggcctcgcgtggc
accaagcaggaggaatttgagagcattgaggaggcgctgcctgacactgacgtgctctac
atgactcgaatccagaaggagcgctttggctctgcgcaggagtatgaagcttgcttcggc
cagttcatcctcactccccacatcatgacccgggccaagaagaagatggtagtgatgcac
ccaatgccccgtgtcaatgagataagcgtggaggtggactcggacccccgagcagcctac
ttccgccaggctgagaatggcatgtacatgcgtatggctctgttagctactgtgctgggc
cgcttctag

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