KEGG   Manis javanica (Malayan pangolin): 108392844
Entry
108392844         CDS       T06054                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv04010  MAPK signaling pathway
mjv04015  Rap1 signaling pathway
mjv04218  Cellular senescence
mjv04620  Toll-like receptor signaling pathway
mjv04664  Fc epsilon RI signaling pathway
mjv04668  TNF signaling pathway
mjv04714  Thermogenesis
mjv04750  Inflammatory mediator regulation of TRP channels
mjv04912  GnRH signaling pathway
mjv04935  Growth hormone synthesis, secretion and action
mjv04936  Alcoholic liver disease
mjv05014  Amyotrophic lateral sclerosis
mjv05022  Pathways of neurodegeneration - multiple diseases
mjv05132  Salmonella infection
mjv05135  Yersinia infection
mjv05145  Toxoplasmosis
mjv05161  Hepatitis B
mjv05169  Epstein-Barr virus infection
mjv05170  Human immunodeficiency virus 1 infection
mjv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mjv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108392844 (MAP2K3)
   04015 Rap1 signaling pathway
    108392844 (MAP2K3)
   04668 TNF signaling pathway
    108392844 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    108392844 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    108392844 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    108392844 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    108392844 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    108392844 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    108392844 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    108392844 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108392844 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    108392844 (MAP2K3)
   05161 Hepatitis B
    108392844 (MAP2K3)
   05169 Epstein-Barr virus infection
    108392844 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108392844 (MAP2K3)
   05135 Yersinia infection
    108392844 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108392844 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    108392844 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    108392844 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108392844 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108392844 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mjv01001]
    108392844 (MAP2K3)
Enzymes [BR:mjv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     108392844 (MAP2K3)
Protein kinases [BR:mjv01001]
 Serine/threonine kinases: STE group
  STE7 family
   108392844 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH RIO1 DUF4344
Other DBs
NCBI-GeneID: 108392844
NCBI-ProteinID: XP_017508808
LinkDB
Position
Unknown
AA seq 347 aa
MESPASSQPASLPQSKGKSRRKKDLRISCVSKPPAPSPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEVLGEDL
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcacccgcctctagccagcccgccagtttgccccagtccaaaggaaaatccagg
aggaagaaggatttgcggatatcctgcgtgtccaagcctcctgcgcctagccccacaccc
ccccggaacctggactcccggactttcatcaccattggagacaggaactttgaggtggag
gctgatgacctggtcaccatctcggagctgggccgtggagcctatggggtggtggagaag
gtgcggcatgcccagagtggcaccatcatggccgttaagcggatccgggccaccgtgaac
tcacaggagcagaagcgtctgctcatggatttggacgtcaacatgcgcacggtggactgt
ttctatactgtcaccttctacggggccctcttcagagagggagatgtgtggatctgcatg
gagctaatggacacatcgctggacaagttctaccggaaggtgctcgataaaaacatgaca
attccagaagacatcttgggggagattgctgtgtctatcgtgagggccctggagcacctg
cacagcaagctgtccgtgatccacagagatgtgaagccatccaacgtcctcatcaacaag
gagggccacgtgaagatgtgcgactttgggatcagtggctacttggtggattctgtggcc
aagacgatggatgctggctgcaagccttacatggcccccgagagaatcaacccggagctg
aaccagaagggctacaatgtcaagtcggatgtctggagcctgggcatcaccatgatcgag
atggccattctgcggtttccttatgagtcctggggtaccccgttccagcagctgaagcag
gtggtggaggaaccgtccccccagctcccagctgaccgtttctctcctgagtttgtggac
ttcactgcacagtgcctgaggaaaaaccctgcggagcgcatgagctacctggaactgatg
gagcaccctttcttcaccttgcacaaaaccaagaagacggacattgctgcctttgtgaag
gaggtccttggggaggacttgtag

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