KEGG   Manis javanica (Malayan pangolin): 108394636
Entry
108394636         CDS       T06054                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv01522  Endocrine resistance
mjv04010  MAPK signaling pathway
mjv04015  Rap1 signaling pathway
mjv04068  FoxO signaling pathway
mjv04071  Sphingolipid signaling pathway
mjv04114  Oocyte meiosis
mjv04148  Efferocytosis
mjv04218  Cellular senescence
mjv04261  Adrenergic signaling in cardiomyocytes
mjv04370  VEGF signaling pathway
mjv04380  Osteoclast differentiation
mjv04517  IgSF CAM signaling
mjv04550  Signaling pathways regulating pluripotency of stem cells
mjv04611  Platelet activation
mjv04613  Neutrophil extracellular trap formation
mjv04620  Toll-like receptor signaling pathway
mjv04621  NOD-like receptor signaling pathway
mjv04622  RIG-I-like receptor signaling pathway
mjv04625  C-type lectin receptor signaling pathway
mjv04657  IL-17 signaling pathway
mjv04658  Th1 and Th2 cell differentiation
mjv04659  Th17 cell differentiation
mjv04660  T cell receptor signaling pathway
mjv04664  Fc epsilon RI signaling pathway
mjv04668  TNF signaling pathway
mjv04670  Leukocyte transendothelial migration
mjv04714  Thermogenesis
mjv04722  Neurotrophin signaling pathway
mjv04723  Retrograde endocannabinoid signaling
mjv04728  Dopaminergic synapse
mjv04750  Inflammatory mediator regulation of TRP channels
mjv04912  GnRH signaling pathway
mjv04914  Progesterone-mediated oocyte maturation
mjv04917  Prolactin signaling pathway
mjv04926  Relaxin signaling pathway
mjv04932  Non-alcoholic fatty liver disease
mjv04933  AGE-RAGE signaling pathway in diabetic complications
mjv04935  Growth hormone synthesis, secretion and action
mjv04936  Alcoholic liver disease
mjv05014  Amyotrophic lateral sclerosis
mjv05020  Prion disease
mjv05022  Pathways of neurodegeneration - multiple diseases
mjv05132  Salmonella infection
mjv05133  Pertussis
mjv05135  Yersinia infection
mjv05140  Leishmaniasis
mjv05142  Chagas disease
mjv05145  Toxoplasmosis
mjv05152  Tuberculosis
mjv05161  Hepatitis B
mjv05163  Human cytomegalovirus infection
mjv05167  Kaposi sarcoma-associated herpesvirus infection
mjv05169  Epstein-Barr virus infection
mjv05170  Human immunodeficiency virus 1 infection
mjv05171  Coronavirus disease - COVID-19
mjv05205  Proteoglycans in cancer
mjv05208  Chemical carcinogenesis - reactive oxygen species
mjv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mjv05415  Diabetic cardiomyopathy
mjv05417  Lipid and atherosclerosis
mjv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108394636 (MAPK14)
   04015 Rap1 signaling pathway
    108394636 (MAPK14)
   04370 VEGF signaling pathway
    108394636 (MAPK14)
   04668 TNF signaling pathway
    108394636 (MAPK14)
   04068 FoxO signaling pathway
    108394636 (MAPK14)
   04071 Sphingolipid signaling pathway
    108394636 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    108394636 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    108394636 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    108394636 (MAPK14)
   04218 Cellular senescence
    108394636 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    108394636 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108394636 (MAPK14)
   04613 Neutrophil extracellular trap formation
    108394636 (MAPK14)
   04620 Toll-like receptor signaling pathway
    108394636 (MAPK14)
   04621 NOD-like receptor signaling pathway
    108394636 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    108394636 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    108394636 (MAPK14)
   04660 T cell receptor signaling pathway
    108394636 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    108394636 (MAPK14)
   04659 Th17 cell differentiation
    108394636 (MAPK14)
   04657 IL-17 signaling pathway
    108394636 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    108394636 (MAPK14)
   04670 Leukocyte transendothelial migration
    108394636 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    108394636 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    108394636 (MAPK14)
   04917 Prolactin signaling pathway
    108394636 (MAPK14)
   04926 Relaxin signaling pathway
    108394636 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    108394636 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108394636 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    108394636 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    108394636 (MAPK14)
   04722 Neurotrophin signaling pathway
    108394636 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    108394636 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108394636 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    108394636 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    108394636 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    108394636 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108394636 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    108394636 (MAPK14)
   05161 Hepatitis B
    108394636 (MAPK14)
   05171 Coronavirus disease - COVID-19
    108394636 (MAPK14)
   05163 Human cytomegalovirus infection
    108394636 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108394636 (MAPK14)
   05169 Epstein-Barr virus infection
    108394636 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108394636 (MAPK14)
   05135 Yersinia infection
    108394636 (MAPK14)
   05133 Pertussis
    108394636 (MAPK14)
   05152 Tuberculosis
    108394636 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108394636 (MAPK14)
   05140 Leishmaniasis
    108394636 (MAPK14)
   05142 Chagas disease
    108394636 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    108394636 (MAPK14)
   05020 Prion disease
    108394636 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    108394636 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108394636 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    108394636 (MAPK14)
   05415 Diabetic cardiomyopathy
    108394636 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108394636 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    108394636 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    108394636 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    108394636 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mjv01001]
    108394636 (MAPK14)
Enzymes [BR:mjv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     108394636 (MAPK14)
Protein kinases [BR:mjv01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   108394636 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 108394636
NCBI-ProteinID: XP_036854303
LinkDB
Position
Unknown
AA seq 365 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAT
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKNDDTLWTFEMLISDLILRTALH
ICTEL
NT seq 1098 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaagagctgaacaagacaatctgggaggtg
cccgagcgttaccagaatctgtccccggtgggctccggcgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttgcgtgtagcagtgaagaagctatccagaccatttcag
tccattattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgttttcacacctgcaaggtctctggaggagttcaat
gatgtgtatttggtgacccatctcatgggggcagatctgaacaacattgtgaagtgtcag
aagcttacagatgaccatgttcagtttcttatttaccaaattctccgaggcctcaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggctcgacacacagatgatgaaatgaca
ggctacgtggccactaggtggtacagggctcctgagatcatgctgaattggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acattgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaactacattcag
tctttgacccagatgccgaagatgaactttgcaaatgtatttattggtgccaatcccttg
gctgtcgacttgctggagaagatgcttgtattagactcagacaagagaatcacagccacc
caagcccttgcgcatgcctactttgctcagtaccacgatcctgatgatgaaccagtggct
gatccttacgatcagtcctttgaaagcagggacctccttatagatgaatggaaaaatgat
gacaccctctggacctttgagatgcttatatctgacctgattttgcgtacagcccttcac
atctgcacagagctttga

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