Manis javanica (Malayan pangolin): 108401094
Help
Entry
108401094 CDS
T06054
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv01524
Platinum drug resistance
mjv04010
MAPK signaling pathway
mjv04071
Sphingolipid signaling pathway
mjv04141
Protein processing in endoplasmic reticulum
mjv04210
Apoptosis
mjv04530
Tight junction
mjv04668
TNF signaling pathway
mjv04714
Thermogenesis
mjv04722
Neurotrophin signaling pathway
mjv04932
Non-alcoholic fatty liver disease
mjv04936
Alcoholic liver disease
mjv05010
Alzheimer disease
mjv05012
Parkinson disease
mjv05014
Amyotrophic lateral sclerosis
mjv05016
Huntington disease
mjv05017
Spinocerebellar ataxia
mjv05022
Pathways of neurodegeneration - multiple diseases
mjv05208
Chemical carcinogenesis - reactive oxygen species
mjv05417
Lipid and atherosclerosis
mjv05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
108401094 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108401094 (MAP3K5)
04668 TNF signaling pathway
108401094 (MAP3K5)
04071 Sphingolipid signaling pathway
108401094 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
108401094 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
108401094 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
108401094 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
108401094 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
108401094 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
108401094 (MAP3K5)
05012 Parkinson disease
108401094 (MAP3K5)
05014 Amyotrophic lateral sclerosis
108401094 (MAP3K5)
05016 Huntington disease
108401094 (MAP3K5)
05017 Spinocerebellar ataxia
108401094 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
108401094 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108401094 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
108401094 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
108401094 (MAP3K5)
04932 Non-alcoholic fatty liver disease
108401094 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
108401094 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108401094 (MAP3K5)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
108401094 (MAP3K5)
Protein kinases [BR:
mjv01001
]
Serine/threonine kinases: STE group
STE11 family
108401094 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
APG6_N
Motif
Other DBs
NCBI-GeneID:
108401094
NCBI-ProteinID:
XP_036850601
LinkDB
All DBs
Position
Unknown
AA seq
1374 aa
AA seq
DB search
MSAEAGEGITFSVPPLAPSGLCALAEGGSCRRGGAAAAAEREDTQRAPPPPGSLWNLESA
AAPGAGLPAASSGSSATRCRGISGGGGGRRTTVAYVINEESQGQLVMAESEALQSLREAC
ETVGAALETLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANN
IILYCDNNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQP
NFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIR
QRVDNTEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALN
RRNLPGDRSKALDVMIPLVQSEEQVASDMYCLVGRIYKDMFLDSNFMDTESRDHGASWFK
KAFESEPSLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGF
FLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVD
FWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIH
EWNFSASSIRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRS
TEEGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
PLHEEIALHKHLKHRNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTI
GFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFT
GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVH
PEIPESMSEEAKAFILKCFEPDPDKRACANDLLIDEFLKVSSKKKKTQPKLSALSAGSNE
YLRSISLPVPVLVEDASSSSEYGSVSPDTELKVDPFNFKTRAKSCGEKDVKGIRTLFLGI
PDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMETLAQGAEEP
KLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQMVLFSFQDAVNK
VLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDDHEE
HPSNQTVRRPPAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELI
QKEKELQAFLHQAIEEKEQEIKNLKLKSQPIDIPGLPVCHLSSPDTNTEGSELTDWLREN
GADEDTISQFLAEDYSLVDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQT
NT seq
4125 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggccggagagggcatcacgttctccgtgcctcccctcgccccctcgggc
ctctgcgcgctcgccgagggcggcagctgccggaggggaggcgcggcggccgcggccgag
cgcgaggacacccagcgagccccgccgccgccgggcagcttgtggaacctggagagtgcc
gccgctcctggcgccgggttaccagctgcctcctccgggagcagcgccacccggtgccgg
ggcatctccgggggcggaggcggccgacgcaccacggtggcttacgtgattaacgaagag
agccaagggcagctggtgatggccgagagcgaggctctgcagagcctgcgggaggcgtgc
gagacggtgggcgccgccttggagaccctgcattttggtaaactggacttcggggaaacc
gcggtgctggaccgtttttacaatgcagatattgctgtggtggagatgagtgatgccttc
aggcagccttctttgttttaccacctgggagtgagagaaagtttcagcatggccaataac
atcatcctctactgtgacaataattcagactctcttcagtcgctgaaggaaatcatttgc
cagaagaatactatgtgcactgggaactacacgtttgttccttacatgataactccacac
aacaaggtctactgctgtgacagcagcttcatgaaggggttgacagagctcatgcaacca
aacttcgagctgctgctcggacccatctgcttaccacttgtggaccgtttcattcagctt
ctgaaggtggcacaagcaagttccagccagtatttccgggaatctatactcaatgatatc
cggaaagctcgtaatttatacactggtaaagaactggcagctgaattggcaagaattcga
cagcgagtggacaatactgaagtcttgacagcagatattgtcataaatctgttactttcc
tacagagatatccaggactatgattctattgtgaagctggtagagactttagaaaaactg
ccaacctttgatttggcctctcatcaccatgtgaagtttcattatgcatttgcactgaac
aggagaaatctccctggagataggtcaaaagctcttgatgttatgattcctctggtgcaa
agtgaagagcaagttgcttcagatatgtactgcttagttggtcgaatctacaaagatatg
tttttggactctaatttcatggacactgaaagtagagaccatggagcttcctggttcaaa
aaggcatttgaatctgagccatcactacagtcaggaattaattatgccgtcctccttctg
gcagctgggcaccagtttgagtcttcctttgagctccggaaagttggggtgaagctaagt
agccttcttggtaaaaagggaaacttagaaaaactccagagctactgggaagttggattt
tttctgggagccagtgtgttggccaatgaccacatgagagttattcaagcatctgaaaag
ctttttaaactgaagacaccagcatggtacctcaagtcaattgtagagacaattttgata
tataagcattttgtgaaactgactacagaacagcctgtggccaagcaggaacttgtggac
ttctggatggatttcctggtggaagccacaaagacagatgttactgtagttaggtttcct
gtattaatattagaaccaaccaaaatctatcaaccttcttatttatctatcaacaatgaa
gttgaggagaagacaatatctatttggcacgtgcttcctgatgacaagaaaggtatacat
gaatggaattttagtgcttcttccatcaggggagtgagtatttctaaatttgaagaacga
tgctgttttctttatgtgcttcataattctgacgatttccagatctatttctgtacagaa
cttcattgcaaaaagttttttgaaatggtgaacaccattactgaagagaaggggagaagt
acagaggaaggagattgtgaaggtgactccctggagtatgactatgaatatgatgaaaat
ggtgacagagtcgttttaggaaaaggcacttatgggatagtctatgcaggtcgggacctg
agcaaccaggtcagaattgctatcaaagaaatcccagagagagacagcaggtactcccag
cccctacatgaagaaatagcactgcataagcatctgaagcacagaaatattgtccagtat
ctgggctcttttagtgagaatggtttcattaaaatcttcatggagcaggtcccaggagga
agtctttctgctctccttcgttccaaatggggcccactgaaagacaatgagcaaaccatt
ggcttttatacaaagcaaatacttgaaggattaaaatacctccatgacaatcagatagtt
caccgagatataaagggtgacaatgtgttgataaatacctatagtggtgttctcaagatc
tctgacttcggaacatcaaagagattggctggcataaatccatgtaccgaaacatttact
ggtacccttcaatatatggcaccagaaataatcgataaaggaccaagaggctacggaaaa
gcagcggacatttggtctttgggctgcacaatcattgaaatggccacagggaaaccaccc
ttttatgaactgggagaaccacaagcagctatgttcaaggtgggaatgtttaaagtccac
ccagagatcccagagtccatgtcggaagaggccaaggcattcatactgaaatgttttgaa
ccagatcctgacaagagagcctgtgctaatgacttgcttattgatgagttcctaaaggtt
tcaagcaaaaagaaaaagacacaacctaagctttcagctctctcagctggatcaaatgag
tatctgaggagcatatccttgcccgtgccggtcctggtggaggatgccagcagcagcagc
gagtatggctcagtctcccccgacacggagctaaaagtggacccattcaatttcaaaaca
agagccaaatcctgcggagaaaaagacgtaaaaggaatacggacgctctttttgggcatt
ccagatgaaaattttgaagatcatagtgctccaccttccccggaagagaaagactctgga
ttctttatgctaaggaaggacagtgaaagacgggccacccttcacaggatcctgacggaa
gaccaagacaaggtcgtgagaaacctaatggaaactttggctcagggggctgaagaacct
aaactaaaatgggagcacatcacaaccctcatcgcaagcctcagagaatttgtgagatcc
actgatcgaaaaatcattgccacaacactgtcaaagctgaagttagagcttgactttgac
agccatggcattagtcaagtccaaatggtgctctttagttttcaagatgctgtcaataaa
gttcttcggaatcataacatcaagccacactggatgtttgccttagacagtatcatccga
aaggcagtgcagacagccattaccattctggttccagaactgaggccgcacttcagcctt
gcatctgagagtgatactgctgatcaagaagacttggatgcagaagacgaccatgaggaa
cacccttcaaaccaaactgtccgaagacctcctgctgtcattgaagatgctgtggctacc
tcaggggtgagcacgctcagttccacggtatcccacgattcccagagtgctcaccgatcc
ctgaatgtacagcttggaaggatgaaaatagaaactaatagattgttggaagaattgatt
cagaaagagaaagaattacaagcttttctccatcaagctattgaagaaaaagaacaagaa
attaaaaacctgaagcttaagtcccaaccaatagatatccccggactgcctgtgtgtcac
ctcagttctcctgacacaaacacggaaggttccgaacttactgactggctgagagaaaat
ggagctgatgaagacactataagtcagtttctggctgaggattattcactagtggatgtt
ctctactatgttacacgtgatgatttaaaatgcctgagactaaggggagggatgctatgc
acactgtggaaggccatcactgactttcgagacaaacaaacttga
DBGET
integrated database retrieval system
