KEGG   Mustela lutreola (European mink): 131838863
Entry
131838863         CDS       T09578                                 
Symbol
IRAK4
Name
(RefSeq) interleukin-1 receptor-associated kinase 4 isoform X1
  KO
K04733  interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk04010  MAPK signaling pathway
mlk04064  NF-kappa B signaling pathway
mlk04620  Toll-like receptor signaling pathway
mlk04621  NOD-like receptor signaling pathway
mlk04722  Neurotrophin signaling pathway
mlk04936  Alcoholic liver disease
mlk05132  Salmonella infection
mlk05133  Pertussis
mlk05135  Yersinia infection
mlk05140  Leishmaniasis
mlk05142  Chagas disease
mlk05145  Toxoplasmosis
mlk05152  Tuberculosis
mlk05161  Hepatitis B
mlk05162  Measles
mlk05164  Influenza A
mlk05168  Herpes simplex virus 1 infection
mlk05169  Epstein-Barr virus infection
mlk05170  Human immunodeficiency virus 1 infection
mlk05171  Coronavirus disease - COVID-19
mlk05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    131838863 (IRAK4)
   04064 NF-kappa B signaling pathway
    131838863 (IRAK4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    131838863 (IRAK4)
   04621 NOD-like receptor signaling pathway
    131838863 (IRAK4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    131838863 (IRAK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    131838863 (IRAK4)
   05161 Hepatitis B
    131838863 (IRAK4)
   05171 Coronavirus disease - COVID-19
    131838863 (IRAK4)
   05164 Influenza A
    131838863 (IRAK4)
   05162 Measles
    131838863 (IRAK4)
   05168 Herpes simplex virus 1 infection
    131838863 (IRAK4)
   05169 Epstein-Barr virus infection
    131838863 (IRAK4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    131838863 (IRAK4)
   05135 Yersinia infection
    131838863 (IRAK4)
   05133 Pertussis
    131838863 (IRAK4)
   05152 Tuberculosis
    131838863 (IRAK4)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    131838863 (IRAK4)
   05140 Leishmaniasis
    131838863 (IRAK4)
   05142 Chagas disease
    131838863 (IRAK4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    131838863 (IRAK4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    131838863 (IRAK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlk01001]
    131838863 (IRAK4)
Enzymes [BR:mlk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     131838863 (IRAK4)
Protein kinases [BR:mlk01001]
 Serine/threonine kinases: TKL group
  IRAK family
   131838863 (IRAK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Death Haspin_kinase NDUFV3
Other DBs
NCBI-GeneID: 131838863
NCBI-ProteinID: XP_059041584
LinkDB
Position
8:complement(70552431..70604807)
AA seq 460 aa
MNKPITSSTYVRCLNLGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALL
QTGKSPTCELLFDWGTTNCTVGDLVDLLIQNEFFAAASLLLPDAVPKTVNILPSNEAVTV
QQKQLPLCGKDRTFVVPVQNLEQNFMPPDSSSPENPSLEGSDTRFHNFSFYELKNVTNNF
DERPISLGGNKMGEGGFGVVYKGFVNNKTVAVKKLAAMVDISTEELRQQFDQEIKVMAKC
QHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDDTPPLPWHMRCKIAQDAANGIS
FLHENHHIHRDIKSANILLDKDFTAKISDFGLARASEKFSQTVMTSRIVGTTAYMAPEAL
RGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYVDTKMND
TDPASIEAMYCIASQCLHEKKNKRPDIKKVQQLLQDMTAS
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgaacaaacccataacatcttccacatatgtgcgctgcctcaatcttggactaattagg
aagctgtcagattttattgatcctcaagaaggatggaagaagttagcggtagctattaaa
aaaccatctggtgatgatagatacaatcagtttcacataaggagatttgaagcattactt
caaactggaaaaagccccacttgtgaattactgtttgactggggcaccacaaattgtaca
gttggtgatcttgtggatcttttgattcaaaatgagttttttgccgcagcaagtcttttg
ctaccagatgctgttcccaaaacagttaatatactaccttctaatgaagctgtaacagtt
cagcagaaacagttgcctctctgtggcaaagacaggacatttgtggtacctgtgcagaat
cttgaacaaaattttatgccacctgactcctcaagtccagaaaatccaagtttagaaggt
agtgatacacgttttcacaatttttcattttatgaattgaagaatgtcacaaataatttt
gatgagagacccatttctctcggtggcaacaagatgggagagggaggatttggagttgta
tataaaggcttcgtgaacaacaaaactgtagcagtgaagaaacttgcagcgatggttgac
attagtactgaagaactgagacagcagtttgatcaagaaataaaagttatggcaaagtgt
caacatgagaacttagtagaactgcttggtttctcaagtgatggagatgacctctgctta
gtctatgtttatatgcccaatggctcattgctagacaggctgtcttgcttggatgatact
ccaccactcccttggcatatgagatgcaagattgctcaagatgcagctaatggcatcagc
tttttacatgaaaaccatcatattcatagagacattaaaagtgcaaatatcttactagat
aaagacttcacagccaaaatatctgactttgggcttgcacgggcttctgagaagttttcc
cagacagtcatgactagcagaattgtgggaacaacagcttatatggcacctgaggctctc
cgaggagaaataacacccaaatctgatatctatagctttggtgtggttttattagaaata
ataactggacttccagctgtagatgaacaccgtgaacctcagttattgctagatattaaa
gaagaaattgaagatgaagaaaagacaattgaagactatgttgatacaaagatgaatgac
actgatcccgcttccattgaagctatgtactgcattgctagtcaatgcttgcatgaaaag
aaaaacaagagaccagacattaagaaggttcaacagctgctacaagacatgacagcttct
taa

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