KEGG   PATHWAY: mlx00240
Entry
mlx00240                    Pathway                                
Name
Pyrimidine metabolism - Mirounga leonina (Southern elephant seal)
Class
Metabolism; Nucleotide metabolism
Pathway map
mlx00240  Pyrimidine metabolism
mlx00240

Module
mlx_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:mlx00240]
mlx_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:mlx00240]
mlx_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:mlx00240]
mlx_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mlx00240]
mlx_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:mlx00240]
Other DBs
GO: 0006220 0006213
Organism
Mirounga leonina (Southern elephant seal) [GN:mlx]
Gene
117999599  DCTPP1; dCTP pyrophosphatase 1 [KO:K16904] [EC:3.6.1.12]
117999855  UPB1; beta-ureidopropionase [KO:K01431] [EC:3.5.1.6]
118000158  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial isoform X1 [KO:K01081] [EC:3.1.3.5]
118000687  HDDC2; 5'-deoxynucleotidase HDDC2 isoform X1 [KO:K07023] [EC:3.1.3.89]
118000776  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
118001233  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
118001348  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
118001368  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
118002195  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 isoform X1 [KO:K01510] [EC:3.6.1.5]
118002657  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 isoform X1 [KO:K01511] [EC:3.6.1.6]
118003109  DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1 [KO:K01520] [EC:3.6.1.23]
118003890  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
118004701  TYMS; thymidylate synthase [KO:K00560] [EC:2.1.1.45]
118006047  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
118007006  UMPS; uridine 5'-monophosphate synthase [KO:K13421] [EC:2.4.2.10 4.1.1.23]
118007093  CTPS2; CTP synthase 2 [KO:K01937] [EC:6.3.4.2]
118007288  [KO:K13809] [EC:2.7.4.14]
118007347  [KO:K13809] [EC:2.7.4.14]
118007497  NT5C1B; cytosolic 5'-nucleotidase 1B [KO:K01081] [EC:3.1.3.5]
118007586  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
118007689  CAD; CAD protein isoform X1 [KO:K11540] [EC:6.3.5.5 2.1.3.2 3.5.2.3]
118007865  NT5DC4; 5'-nucleotidase domain-containing protein 4 [KO:K01081] [EC:3.1.3.5]
118010088  DCTD; deoxycytidylate deaminase [KO:K01493] [EC:3.5.4.12]
118010467  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
118011165  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 isoform X1 [KO:K01511] [EC:3.6.1.6]
118011663  UPP2; LOW QUALITY PROTEIN: uridine phosphorylase 2 [KO:K00757] [EC:2.4.2.3]
118011863  DTYMK; thymidylate kinase [KO:K00943] [EC:2.7.4.9]
118014053  UCK2; uridine-cytidine kinase 2 [KO:K00876] [EC:2.7.1.48]
118014509  NME7; nucleoside diphosphate kinase 7 isoform X1 [KO:K00940] [EC:2.7.4.6]
118015087  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X1 [KO:K10808] [EC:1.17.4.1]
118015103  DPYS; dihydropyrimidinase [KO:K01464] [EC:3.5.2.2]
118015699  [KO:K10808] [EC:1.17.4.1]
118017477  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
118017571  UCK1; uridine-cytidine kinase 1 isoform X1 [KO:K00876] [EC:2.7.1.48]
118018012  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
118019104  DPYD; dihydropyrimidine dehydrogenase [NADP(+)] isoform X1 [KO:K00207] [EC:1.3.1.2]
118019446  CMPK1; UMP-CMP kinase [KO:K13800] [EC:2.7.4.14]
118019554  CTPS1; CTP synthase 1 [KO:K01937] [EC:6.3.4.2]
118019581  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
118019927  CDA; cytidine deaminase isoform X1 [KO:K01489] [EC:3.5.4.5]
118020949  NT5C3A; cytosolic 5'-nucleotidase 3A isoform X1 [KO:K24242]
118021288  [KO:K00940] [EC:2.7.4.6]
118021654  NME4; nucleoside diphosphate kinase, mitochondrial [KO:K00940] [EC:2.7.4.6]
118021700  NME3; nucleoside diphosphate kinase 3 isoform X1 [KO:K00940] [EC:2.7.4.6]
118022092  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
118022560  [KO:K00940] [EC:2.7.4.6]
118023603  DHODH; dihydroorotate dehydrogenase (quinone), mitochondrial isoform X1 [KO:K00254] [EC:1.3.5.2]
118023709  TK2; thymidine kinase 2, mitochondrial isoform X1 [KO:K00857] [EC:2.7.1.21]
118024067  UCKL1; uridine-cytidine kinase-like 1 isoform X1 [KO:K00876] [EC:2.7.1.48]
118024204  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
118024215  TK1; thymidine kinase, cytosolic [KO:K00857] [EC:2.7.1.21]
118024281  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type isoform X1 [KO:K01081] [EC:3.1.3.5]
118024522  UPP1; uridine phosphorylase 1 [KO:K00757] [EC:2.4.2.3]
118024744  NME2; nucleoside diphosphate kinase B [KO:K00940] [EC:2.7.4.6]
118024745  NME1; nucleoside diphosphate kinase A [KO:K00940] [EC:2.7.4.6]
118024892  NT5C3B; 7-methylguanosine phosphate-specific 5'-nucleotidase [KO:K24242]
118025703  NT5C2; cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
118026669  ASMTL; probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein isoform X1 [KO:K25435]
Compound
C00015  UDP
C00039  DNA
C00046  RNA
C00055  CMP
C00063  CTP
C00064  L-Glutamine
C00075  UTP
C00086  Urea
C00099  beta-Alanine
C00105  UMP
C00106  Uracil
C00112  CDP
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00169  Carbamoyl phosphate
C00178  Thymine
C00214  Thymidine
C00222  3-Oxopropanoate
C00239  dCMP
C00295  Orotate
C00299  Uridine
C00337  (S)-Dihydroorotate
C00363  dTDP
C00364  dTMP
C00365  dUMP
C00380  Cytosine
C00383  Malonate
C00429  5,6-Dihydrouracil
C00438  N-Carbamoyl-L-aspartate
C00458  dCTP
C00459  dTTP
C00460  dUTP
C00475  Cytidine
C00526  Deoxyuridine
C00672  2-Deoxy-D-ribose 1-phosphate
C00705  dCDP
C00813  Barbiturate
C00881  Deoxycytidine
C00941  3',5'-Cyclic CMP
C01013  3-Hydroxypropanoate
C01103  Orotidine 5'-phosphate
C01168  Pseudouridine 5'-phosphate
C01205  (R)-3-Amino-2-methylpropanoate
C01346  dUDP
C01368  3'-UMP
C01563  Carbamate
C02067  Pseudouridine
C02170  Methylmalonate
C02354  2',3'-Cyclic CMP
C02355  2',3'-Cyclic UMP
C02376  5-Methylcytosine
C02642  3-Ureidopropionate
C03997  5-Hydroxymethyldeoxycytidylate
C05281  5-Methylbarbiturate
C05822  3'-CMP
C06198  P1,P4-Bis(5'-uridyl) tetraphosphate
C11038  2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
C11039  2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
C15607  3-Oxo-3-ureidopropanoate
C20231  (Z)-3-Ureidoacrylate peracid
C20249  (Z)-3-Peroxyaminoacrylate
C20253  Aminoacrylate
C20254  Ureidoacrylate
C20846  3-Oxo-3-ureidoisobutyrate
C21028  (R)-5,6-Dihydrothymine
C21029  (R)-3-Ureidoisobutyrate
C22509  3',5'-Cyclic UMP
Related
pathway
mlx00030  Pentose phosphate pathway
mlx00220  Arginine biosynthesis
mlx00250  Alanine, aspartate and glutamate metabolism
mlx00280  Valine, leucine and isoleucine degradation
mlx00410  beta-Alanine metabolism
KO pathway
ko00240   

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