Mirounga leonina (Southern elephant seal): 118026127
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Entry
118026127 CDS
T07472
Symbol
BACE2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
118026127 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mlx01002
]
118026127 (BACE2)
Enzymes [BR:
mlx01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
118026127 (BACE2)
Peptidases and inhibitors [BR:
mlx01002
]
Aspartic peptidases
Family A1: pepsin family
118026127 (BACE2)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
118026127
NCBI-ProteinID:
XP_034884741
LinkDB
All DBs
Position
Unknown
AA seq
510 aa
AA seq
DB search
GAQAPALLLPLLAQWLLRAAPAPAPAPLTLPLRVAAPTPGPGTPAAPRAAPHADGLALAL
EPAGGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGAPHSYVDS
YFDAERSSTYHSKGFDVTVKYTQGSWTGFVGEDVVTIPKGFNSSFLVNIATIFESENFFL
PGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDVFSMQMCGAGLPVAGSGTNGGS
LVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTL
LRLPQKVFNAVVEAVARTSLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSS
QSFRVTILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRARKRVGF
AASPCAEIAGAPVSEISGPFSTDDVASNCVPALPLNEPILWIVSYTLMSVCGIILLILII
LLLLPFRCRHLPRDPEVVNDESSLVRHRWK
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
ggcgcgcaggccccggcgctgctgctgccgctgctggcccagtggctcctgcgcgcagcc
ccggcgccggcccccgcacccctcacgctgcccctccgcgtggccgcgcccacccccggg
cccgggacccccgccgcgccccgcgccgcgccccacgcggacggcctggcgctcgccctg
gagcccgccggcggcgccgccaacttcttggccatggtggacaacctgcagggcgactct
ggccgtggctactacctggagatgctgatcggaacccccccgcagaagctgcagattctc
gttgacactggaagcagcaacttcgccgtggcaggtgccccgcactcttacgtagactcg
tactttgacgcggagaggtccagtacttaccactccaagggctttgacgtcacggtcaag
tacacgcaaggcagctggacgggcttcgtcggggaggacgttgtcaccatcccgaagggc
ttcaatagctcgtttcttgtcaacatcgccacgatctttgagtcagagaatttctttctg
cctgggatcaagtggaatgggatcctgggactcgcatatgctgctctggccaagccgtca
agttccctggagacgttcttcgattccctggtggcccaggcgaagatacctgatgtcttc
tccatgcagatgtgtggggcggggctgcctgtagctggatctggtaccaacggaggtagt
cttgtcctgggtggaattgagccgagtttgtacaagggagacatctggtatacccctatt
aaggaggagtggtattatcagatagaaattctcaagttggaaattggaggccagagcctg
aatctggactgcagagagtataacgcagacaaggccatcgtggacagtggcaccaccctt
ctgcgcctgccccagaaggtgttcaatgcagtggttgaggccgtggcccgcacgtctctg
attccagaattctctgatggtttctggactgggtcccagctggcttgctggacgaattct
gagacaccttggtcttacttccctaaaatctccatctacctgagagacgagaactccagc
cagtcgttccgtgtaaccatcctgcctcagctctacatccagcccatgatgggggcgggc
ctgaattatgaatgttaccggttcggcatttcaccttccacgaacgcgctggtgatcggt
gctaccgtgatggagggcttctacgtgatcttcgacagagctcggaaaagggtgggcttt
gcggccagcccctgtgcagaaattgcaggtgctccagtgtcggaaatctctgggcctttc
tcaacagacgacgtagccagcaactgcgtccccgccctgcctttgaatgagcccattttg
tggatcgtctcttacacgctcatgagcgtgtgtggaatcatccttctcatcctgatcatc
ctgttgctgctgccctttcggtgtcggcacctgccccgcgatcccgaggtcgtcaatgat
gagtcctctctcgtccggcatcgctggaagtga
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