KEGG   Molossus molossus (Pallas's mastiff bat): 118624174
Entry
118624174         CDS       T07221                                 
Symbol
LRP6
Name
(RefSeq) low-density lipoprotein receptor-related protein 6
  KO
K03068  low density lipoprotein receptor-related protein 5/6
Organism
mmf  Molossus molossus (Pallas's mastiff bat)
Pathway
mmf04150  mTOR signaling pathway
mmf04310  Wnt signaling pathway
mmf04928  Parathyroid hormone synthesis, secretion and action
mmf05010  Alzheimer disease
mmf05022  Pathways of neurodegeneration - multiple diseases
mmf05200  Pathways in cancer
mmf05224  Breast cancer
mmf05225  Hepatocellular carcinoma
mmf05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    118624174 (LRP6)
   04150 mTOR signaling pathway
    118624174 (LRP6)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    118624174 (LRP6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118624174 (LRP6)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    118624174 (LRP6)
   05226 Gastric cancer
    118624174 (LRP6)
   05224 Breast cancer
    118624174 (LRP6)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118624174 (LRP6)
   05022 Pathways of neurodegeneration - multiple diseases
    118624174 (LRP6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmf04131]
    118624174 (LRP6)
Membrane trafficking [BR:mmf04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Low-density lipoprotein receptor (LDLR) family proteins
    118624174 (LRP6)
SSDB
Motif
Pfam: Ldl_recept_b FXa_inhibition Ldl_recept_a DUF5050 Vgb_lyase EGF_LRP2 SGL cEGF EGF
Other DBs
NCBI-GeneID: 118624174
NCBI-ProteinID: XP_036108109
LinkDB
Position
Unknown
AA seq 1343 aa
MDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKDGAT
ELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSF
IDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTKLNGTMRKILISEDLEEP
RAIVLDPMVGYMYWTDWGEIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGD
AKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRSAEREII
IDQLPDLMGLKATNVHRIIGSNPCADENGGCSHLCLYRPQGLRCACPIGFELISDMKTCI
VPEAFLLFSRRADIRRISLETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISR
AFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEASKLDGQHRQVLVWKDLD
SPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWT
DLDTNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTI
IQGHLDYVMDILVFHSSRQAGWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRT
CSAPTTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNM
IRKAQEDGSQGFTVVVSSVLNLEIQPYDLSIDIYSRYIYWTCEATNVITVTRLDGRSIGV
VLKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALD
SRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKI
DMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTRCSC
PMHLVLLQDELSCGEPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCPVCSE
SQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVD
CSDKSDEVDCYPTEEPAPQATNTVGSVIGVIVTIFVSGTIYFICQRMLCPRMKGDGETMT
NDYVVHGPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSGPPYDRAHVTGASS
SSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTT
PCSTDVCDSDYAPSRRMTSVATAKGYTSDLNYDSEPVPPPPTPRSQYLSAEENYESCPPS
PYTERSYSHHLYPPPPSPCTDSS
NT seq 4032 nt   +upstreamnt  +downstreamnt
atggatatacatgccttcagccaacagaggcagccaaatgctacaaatccatgtggaatt
gataatggtggttgttcccacttgtgtttgatgtctccagtcaagcctttttatcagtgt
gcttgcccaactggggtcaaactcctggagaatggaaaaacctgcaaagatggtgccact
gaattattgcttttagcccgaaggaccgacttgagacgcatttctttggatacaccagac
ttcacagacattgttctacagttagaagatatccgtcatgccattgctatagattatgat
cctgtggaaggttatatctactggactgatgatgaagtgagagccatacgccgctcattc
atagatggatctggtagtcagtttgtggtcaccgctcagattgcacaccctgatggtatt
gctgttgactgggttgcccggaatctttattggacagacactggcactgatcggatagaa
gtgacaaagctcaatgggaccatgaggaagatcttgatttcagaggacttagaggaaccc
cgggctattgtgttagatcccatggttgggtacatgtattggactgattggggagaaatc
ccgaaaattgagcgagcagctctggatggttctgaccgagtggtgttggttaacacttct
cttggttggccaaatggtctagccttggattatgatgaaggcaaaatatactggggagat
gccaaaacagacaaaattgaggtgatgaataccgatggcactgggagacgagtactagtg
gaagacaaaattcctcacatcttcgggtttactttgttgggtgactatgtttactggact
gactggcagaggcggagcattgaaagagtacacaaacgaagtgcagagagggaaatcatc
atagatcagctccctgacctcatgggcctaaaggccacaaatgttcatcgaatcattggt
tccaacccctgcgctgatgaaaatgggggatgtagccatctttgcctctatagacctcag
ggccttcgttgtgcctgtcccattggctttgaactcatcagtgacatgaagacctgcatt
gtcccagaggctttccttttgttttctcggagagcagatattaggcgaatttctttggaa
accaacaataataatgtggccattccactcactggcgtcaaagaagcttctgctttggat
tttgatgtaacagacaaccgaatttactggactgatatatcactcaagaccatcagcaga
gcctttatgaatggcagtgcactggaacatgtggtagaatttggcttagattatccagaa
ggcatggcagtagattggcttgggaagaacttgtactgggcagacacaggaacgaatcga
attgaggcatcaaagttggatgggcagcaccgacaagttttggtgtggaaagacctagac
agtcccagagctcttgcgttggaccctgctgaaggattcatgtattggactgagtggggt
ggaaaacctaagatagacagagctgccatggatggaagtgaacgtactacattagttccg
aatgtggggcgtgcaaatggcctaactattgattatgctaaaaggaggctctactggaca
gacctggacaccaatttaatagaatcttcaaatatgctgggactcaaccgtgaagttata
gcagatgacttgcctcatccttttggcttaactcagtaccaagattacatctactggacg
gactggagccgacgcagcattgagcgtgccaacaaaactagtggccaaaaccgcaccatc
attcagggccatttggactatgtgatggacatcctcgtctttcactcctctcggcaggca
gggtggaacgagtgtgcttccagcaatgggcactgctcccacctctgcttggctgtgcca
gtcggaggttttgtctgtggatgtcctgcccactactctctcaatgctgacaacaggaca
tgtagtgctccaactactttcctgctcttcagtcagaagagcgccatcaaccgcatggta
attgatgaacagcagagccccgacatcatccttcctatccacagccttcggaatgtccga
gccattgactatgacccactggataagcaactatattggattgattcacgacaaaacatg
atccggaaagcacaagaagatggcagccagggctttactgtggttgtgagctcagttctg
aatctagaaatacaaccctatgacctcagtattgatatctatagccgctacatctactgg
acttgtgaggccaccaacgtcattactgtcaccagattagatgggagatcaattggagta
gtgctgaaaggcgagcaagacagacctcgagccattgtggtaaacccagagaaagggtat
atgtattttaccaatcttcaggaaaggtctccgaaaattgaacgagctgctttggatgga
acagaacgggaggttctctttttcagtggcttaagtaaaccgattgcgttggcccttgat
agcagattgggcaagctcttctgggctgattcagatctccggcgaattgaaagcagtgat
ctctcaggtgccaaccggatagtattggaagactcgaatatcttgcagcctgtgggacta
actgtgtttgaaaattggctctattggattgataagcagcagcaaatgattgaaaaaatt
gatatgacaggtcgagagggtagaaccaaagtccaggctcgaatagcccaacttagtgac
attcatgctgtaaaggagctgaaccttcaggaatatagacagcacccttgtgctcaggat
aatggtggctgttcacatatttgtcttgtaaaaggagatggtactacaaggtgctcttgc
cccatgcacttggttctgcttcaagatgagctgtcatgtggagaacccccaacatgttct
cctcagcagtttacttgtttcacgggagaaattgactgtatccctgtggcttggcggtgc
gatgggtttactgagtgtgaagaccacagtgatgagctcaattgtcctgtatgctcagag
tcccagttccagtgtgccagtgggcagtgtattgatggtgccctcagatgcaatggagat
gcaaactgccaggataaatcagatgagaagaactgtgaagtgctttgtttaattgatcaa
ttccgctgtgccaatggtcagtgcattggaaaacataagaaatgtgatcataatgtggac
tgcagtgacaaatcagacgaagtggattgttatccaactgaggagccagcaccacaggcc
accaatacagttggttcagttattggagtaattgtcactattttcgtgtctggaaccata
tactttatttgccagagaatgttgtgtccacgtatgaagggagatggagaaaccatgact
aatgactatgtagttcatggaccagcttctgtgccccttggttatgtgccacacccaagc
tctttgtcaggatctcttccaggaatgtctcgaggtaaatccatgatcagctccctcagc
atcatggggggaagcagtggacccccctatgaccgagctcacgtcacaggagcatcatca
agtagttcttcaagcaccaaaggcacttatttccctgcaattttgaatcctccaccatct
ccagccacggagcgatcgcattacactatggaatttggttattcttccaacagtccttcc
actcataggtcctacagctacaggccatacagttaccggcactttgcaccccccaccaca
ccctgcagcacagatgtttgtgacagtgactatgctcccagccggagaatgacctcagtg
gcaacagccaagggctacactagtgacttgaactatgactcagagcctgtgcccccacct
cccacaccccgaagccaatacttgtcagcagaagagaactatgaaagctgcccaccttct
ccttacacagagaggagctactctcatcacctctaccctccaccaccctctccctgtaca
gactcctcctga

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