Marmota marmota marmota (Alpine marmot): 107148359
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Entry
107148359 CDS
T09644
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma01521
EGFR tyrosine kinase inhibitor resistance
mmma01522
Endocrine resistance
mmma04010
MAPK signaling pathway
mmma04014
Ras signaling pathway
mmma04015
Rap1 signaling pathway
mmma04066
HIF-1 signaling pathway
mmma04068
FoxO signaling pathway
mmma04081
Hormone signaling
mmma04114
Oocyte meiosis
mmma04140
Autophagy - animal
mmma04144
Endocytosis
mmma04150
mTOR signaling pathway
mmma04151
PI3K-Akt signaling pathway
mmma04152
AMPK signaling pathway
mmma04211
Longevity regulating pathway
mmma04213
Longevity regulating pathway - multiple species
mmma04510
Focal adhesion
mmma04518
Integrin signaling
mmma04520
Adherens junction
mmma04550
Signaling pathways regulating pluripotency of stem cells
mmma04730
Long-term depression
mmma04913
Ovarian steroidogenesis
mmma04914
Progesterone-mediated oocyte maturation
mmma05200
Pathways in cancer
mmma05202
Transcriptional misregulation in cancer
mmma05205
Proteoglycans in cancer
mmma05214
Glioma
mmma05215
Prostate cancer
mmma05218
Melanoma
mmma05224
Breast cancer
mmma05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
107148359 (Igf1r)
04014 Ras signaling pathway
107148359 (Igf1r)
04015 Rap1 signaling pathway
107148359 (Igf1r)
04066 HIF-1 signaling pathway
107148359 (Igf1r)
04068 FoxO signaling pathway
107148359 (Igf1r)
04151 PI3K-Akt signaling pathway
107148359 (Igf1r)
04152 AMPK signaling pathway
107148359 (Igf1r)
04150 mTOR signaling pathway
107148359 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
107148359 (Igf1r)
04518 Integrin signaling
107148359 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
107148359 (Igf1r)
04140 Autophagy - animal
107148359 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
107148359 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
107148359 (Igf1r)
04520 Adherens junction
107148359 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
107148359 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
107148359 (Igf1r)
04914 Progesterone-mediated oocyte maturation
107148359 (Igf1r)
09156 Nervous system
04730 Long-term depression
107148359 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
107148359 (Igf1r)
04213 Longevity regulating pathway - multiple species
107148359 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107148359 (Igf1r)
05202 Transcriptional misregulation in cancer
107148359 (Igf1r)
05205 Proteoglycans in cancer
107148359 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
107148359 (Igf1r)
05214 Glioma
107148359 (Igf1r)
05218 Melanoma
107148359 (Igf1r)
05215 Prostate cancer
107148359 (Igf1r)
05224 Breast cancer
107148359 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107148359 (Igf1r)
01522 Endocrine resistance
107148359 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107148359 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mmma04090
]
107148359 (Igf1r)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
107148359 (Igf1r)
Protein kinases [BR:
mmma01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
107148359 (Igf1r)
CD molecules [BR:
mmma04090
]
Proteins
107148359 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
FN3_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
107148359
NCBI-ProteinID:
XP_015348476
Ensembl:
ENSMMMG00000020867
LinkDB
All DBs
Position
Unknown
AA seq
1347 aa
AA seq
DB search
HVLPLPSCLLSVCGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTV
ITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGA
IRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPLCEKTTINNE
YNYRCWTTNRCQKMCPSVCGKRACTENNECCHQECLGSCHAPDNDTACVACRHYFYEGVC
VPACPPDTYRFEGWRCVKRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGTQSMY
CIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGL
IEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLT
IKSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTT
WKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNK
DVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSA
SNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDV
EEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRR
DVMQVANTTMSSRSRNTTVMDSYNMTDPEELETEYPFFESRVDNKERTVISNLRPFTLYR
IDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEARPENSIFLKWAEPENPNG
LILMYEIKYGSQIEDQRECVSRQDYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPV
FFYVPAKTTYENFIHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEY
FSAADVYIPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAAS
MRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEIEN
NPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDI
YETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQ
VLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKDEMEPGFREVSFY
YSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASF
DERRPYAHMNGGRTDERALPLPQSSTC
NT seq
4044 nt
NT seq
+upstream
nt +downstream
nt
catgtcctgcctttgccctcttgtctcctttcagtctgtggcccgggcattgacatacgc
aacgactatcagcagctgaagcgcctggagaactgcacggtgatagagggctacctccac
atcctgctcatctccaaggctgaggactaccgcagctaccgtttccccaagctcacagtc
atcactgaatacttgctgctgttccgcgtggctggcctagagagcctcggagacctcttc
ccgaacctcacagtcatccgcggctggaaacttttttacaactacgccctggtcatcttt
gagatgactaatctcaaggatattgggctttataacctgaggaacattactcggggtgcc
atcaggattgaaaaaaatgctgatctctgttacctctccacagtggactggtctttgatc
ctagatgcagtgtccaataattatattgtggggaacaagcccccaaaggaatgtggggac
ctgtgtccagggaccatggaggagaagccattgtgtgagaagaccaccatcaataatgag
tacaactaccgctgttggaccacaaatcgctgccagaaaatgtgcccgagcgtgtgcgga
aagcgggcgtgcaccgagaacaatgaatgctgccaccaggaatgcctgggcagctgccac
gcacccgacaatgacacagcctgcgtggcctgccggcactacttctatgagggcgtgtgt
gtgcctgcctgcccgcctgacacctacaggttcgagggatggcgctgcgtgaagcgcgac
ttctgtgccaacatcctcagcgctgagagcagtgactctgagggcttcgtcatccatgac
ggcgagtgcatgcaggagtgcccctcaggcttcatccgcaacggcacccagagcatgtac
tgcatcccttgcgaaggtccttgccccaaagtctgtgaagaagagaagaaaacaaagact
attgattctgttacttctgctcagatgctccaaggatgtaccatcttcaagggcaatttg
ctcattaatatccgacgaggcaataacattgcctcagaactggagaacttcatggggctc
atcgaggtggtgaccggctatgtgaagatccgccattcccatgccttggtctccttgtcc
ttccttaagaaccttcgccagatcttaggggaggagcaactggaagggaactattccttc
tatgtcttggataaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaatctgggaaaatgtactttgctttcaatcccaaactgtgtgtttctgaaatttac
cgcatggaggaagtaacagggacaaaagggcgccaaagcaaaggagacataaacaccaga
aacaatggagaaagagcctcctgtgaaagtgatgtcctacatttcacatccaccaccacg
tggaagaaccgcattatcataacctggcaccggtaccggcccccggactacagggatctc
atcagcttcactgtttactacaaggaggcaccctttaaaaatgtcacagaatatgatggg
caggatgcctgtggctccaatagctggaacatggtggacgtggacctccctcccaacaaa
gatgtggaacctggcattttactgcatgggctgaagccctggactcaatacgcagtctat
gtcaaggccgtgaccctcaccatggtggagaatgaccacattcgtggggccaagagtgaa
atcttgtacattcgtaccaatgcttcagttccttccattcccctggatgtcctttcagca
tcgaactcctcttctcagctgattgtgaaatggaaccccccatctctacccaacggtaac
ctgagttactacattgtgagatggcagcggcagcctcaggacggctacctgtaccggcat
aattactgttccaaagacaaaatccccatcaggaagtatgctgatggcaccattgatgtc
gaagaggtaacagagaatcccaagactgaagtgtgtggtggtgagaaagggccttgctgt
gcttgccctaaaactgaagctgagaagcaagctgagaaggaggaggctgaataccgcaaa
gtctttgagaatttcctgcataactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacagtgatg
gactcctacaatatgacagatccagaagaacttgagacagagtaccctttctttgagagc
agagtggataacaaggagagaactgtcatctctaacctccggccttttactttgtaccgc
attgatattcacagctgtaatcatgaggctgagaagctgggctgtagtgcctctaacttt
gtctttgccagaaccatgcctgcagaaggagcagatgacattcctggcccagttacctgg
gaggcaaggcctgagaactccatctttttaaagtgggcagaacctgagaaccccaatgga
ttgattctaatgtatgaaataaaatacggatcacaaattgaggatcagcgagaatgtgtg
tccagacaggattatagaaaatatggaggggccaagctcaaccggctaaacccagggaac
tataccgcacggattcaggctacctctctctctgggaatgggtcatggacagatcctgtg
ttcttctatgtcccagccaaaacaacgtatgagaatttcatccatctgatcatcgctctg
ccggtcgccatcctgttgatcgtgggagggctggtgataatgctgtatgtcttccataga
aagaggaataacagcaggctggggaatggagtgctgtatgcctctgtaaacccagagtac
ttcagcgcagccgatgtgtacattcctgacgagtgggaggtcgctcgagagaaaatcacc
atgagccgggagctggggcaggggtccttcgggatggtctacgaaggagttgccaagggt
gtggttaaagatgaacctgaaaccagggtggctatcaagacagtgaacgaggctgccagc
atgcgtgaaaggattgagtttctgaacgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggcgtggtgtcccagggccagccaacgctggtcatcatggaa
ctgatgacacggggggatctcaaaagttatctcagatctctgaggccagaaatagagaat
aacccagtccttgcacctccaagcctaagcaagatgatccagatggctggagaaattgca
gatggtatggcatatctcaatgctaacaagtttgtccacagagaccttgctgcccgaaat
tgcatggtggccgaagatttcacagtcaaaattggagattttggtatgacaagagatatc
tatgagacagactattaccggaaaggagggaaagggttgctgcctgtgcgctggatgtct
cctgagtccctcaaggatggagtcttcaccactcattcagacgtctggtccttcggggtt
gtcctctgggagatcgccacactggccgagcagccgtaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggaaggtggccttctagacaagccggacaactgccccgacatg
ctgtttgagttgatgcgcatgtgctggcagtacaaccccaagatgagaccttccttcctg
gaaatcatcagcagcatcaaagacgagatggaacctggttttcgggaggtctccttctac
tacagtgaggagaacaagccacctgaacctgaggagctggacctggagcctgaaaacatg
gagagtgtccccctggacccctcggcctcatcatcatccctgccgctgcccgacagacac
tcaggacacaaggctgagaatggcccaggccctggggtgctggttctccgagccagcttc
gatgagagacggccttacgcgcacatgaatggaggacgcacagatgagagagccttgccg
ctgccccagtcttcaacctgctga
DBGET
integrated database retrieval system
