KEGG   PATHWAY: mmu03250
Entry
mmu03250                    Pathway                                
Name
Viral life cycle - HIV-1 - Mus musculus (house mouse)
Class
Genetic Information Processing; Information processing in viruses
Pathway map
mmu03250  Viral life cycle - HIV-1
mmu03250

Organism
Mus musculus (house mouse) [GN:mmu]
Gene
12774  Ccr5; C-C motif chemokine receptor 5 [KO:K04180]
12767  Cxcr4; C-X-C motif chemokine receptor 4 [KO:K04189]
12504  Cd4; CD4 antigen [KO:K06454]
17754  Map1a; microtubule-associated protein 1 A [KO:K10429]
17755  Map1b; microtubule-associated protein 1B [KO:K10429]
270058  Map1s; microtubule-associated protein 1S [KO:K10429]
235180  Fez1; fasciculation and elongation protein zeta 1 [KO:K25663]
12121  Bicd1; BICD cargo adaptor 1 [KO:K18739]
76895  Bicd2; BICD cargo adaptor 2 [KO:K18739]
209387  Trim30d; tripartite motif-containing 30D [KO:K10648] [EC:2.3.2.27]
319236  Trim12c; tripartite motif-containing 12C [KO:K10648] [EC:2.3.2.27]
667823  Trim5; tripartite motif-containing 5 [KO:K10648] [EC:2.3.2.27]
80287  Apobec3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 [KO:K18750] [EC:3.5.4.-]
56045  Samhd1; SAM domain and HD domain, 1 [KO:K22544] [EC:3.1.5.-]
101739  Psip1; PC4 and SFRS1 interacting protein 1 [KO:K25057]
23988  Pin1; peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 [KO:K09578] [EC:5.2.1.8]
241593  Pin1rt1; peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1, retrogene 1 [KO:K09578] [EC:5.2.1.8]
20587  Smarcb1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 [KO:K11648]
268373  Ppia; peptidylprolyl isomerase A [KO:K03767] [EC:5.2.1.8]
668548  Gm9234; predicted pseudogene 9234 [KO:K03767] [EC:5.2.1.8]
269061  Cpsf7; cleavage and polyadenylation specific factor 7 [KO:K14398]
432508  Cpsf6; cleavage and polyadenylation specific factor 6 [KO:K14398]
320938  Tnpo3; transportin 3 [KO:K15436]
17857  Mx1; MX dynamin-like GTPase 1 [KO:K14754]
17858  Mx2; MX dynamin-like GTPase 2 [KO:K14754]
19386  Ranbp2; RAN binding protein 2 [KO:K12172] [EC:2.3.2.-]
218210  Nup153; nucleoporin 153 [KO:K14296]
12914  Crebbp; CREB binding protein [KO:K04498] [EC:2.3.1.48]
328572  Ep300; E1A binding protein p300 [KO:K04498] [EC:2.3.1.48]
14534  Kat2a; K(lysine) acetyltransferase 2A [KO:K06062] [EC:2.3.1.48]
18519  Kat2b; K(lysine) acetyltransferase 2B [KO:K06062] [EC:2.3.1.48]
16543  Mdfic; MyoD family inhibitor domain containing [KO:K27688]
107951  Cdk9; cyclin dependent kinase 9 [KO:K02211] [EC:2.7.11.22 2.7.11.23]
12455  Ccnt1; cyclin T1 [KO:K15188]
72949  Ccnt2; cyclin T2 [KO:K15188]
93736  Aff4; AF4/FMR2 family, member 4 [KO:K15185]
13716  Ell; elongation factor RNA polymerase II [KO:K15183]
192657  Ell2; elongation factor for RNA polymerase II 2 [KO:K15183]
269344  Ell3; elongation factor RNA polymerase II-like 3 [KO:K15183]
64144  Mllt1; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 [KO:K15187]
70122  Mllt3; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 [KO:K15187]
24116  Nelfa; negative elongation factor complex member A, Whsc2 [KO:K15179]
58202  Nelfb; negative elongation factor complex member B [KO:K15180]
57314  Nelfcd; negative elongation factor complex member C/D, Th1l [KO:K15181]
27632  Nelfe; negative elongation factor complex member E, Rdbp [KO:K15182]
100041294  Supt4b; SPT4B, DSIF elongation factor subunit [KO:K15171]
20922  Supt4a; SPT4A, DSIF elongation factor subunit [KO:K15171]
20924  Supt5; suppressor of Ty 5, DSIF elongation factor subunit [KO:K15172]
103573  Xpo1; exportin 1 [KO:K14290]
19384  Ran; RAN, member RAS oncogene family [KO:K07936]
19428  Rasl2-9; RAS-like, family 2, locus 9 [KO:K07936]
75471  1700009N14Rik; RIKEN cDNA 1700009N14 gene [KO:K07936]
18550  Furin; furin, paired basic amino acid cleaving enzyme [KO:K01349] [EC:3.4.21.75]
26943  Serinc3; serine incorporator 3 [KO:K25661]
218442  Serinc5; serine incorporator 5 [KO:K25655]
69550  Bst2; bone marrow stromal cell antigen 2 [KO:K06731]
15239  Hgs; HGF-regulated tyrosine kinase substrate [KO:K12182]
22088  Tsg101; tumor susceptibility gene 101 [KO:K12183]
208092  Chmp6; charged multivesicular body protein 6 [KO:K12195]
75608  Chmp4b; charged multivesicular body protein 4B [KO:K12194]
18571  Pdcd6ip; programmed cell death 6 interacting protein [KO:K12200]
116733  Vps4a; vacuolar protein sorting 4A [KO:K12196]
20479  Vps4b; vacuolar protein sorting 4B [KO:K12196]
Reference
  Authors
Li G, De Clercq E
  Title
HIV Genome-Wide Protein Associations: a Review of 30 Years of Research.
  Journal
Microbiol Mol Biol Rev 80:679-731 (2016)
DOI:10.1128/MMBR.00065-15
Reference
  Authors
Tagliamonte M, Tornesello ML, Buonaguro FM, Buonaguro L
  Title
Conformational HIV-1 envelope on particulate structures: a tool for chemokine coreceptor binding studies.
  Journal
J Transl Med 9 Suppl 1:S1 (2011)
DOI:10.1186/1479-5876-9-S1-S1
Reference
  Authors
Novikova M, Zhang Y, Freed EO, Peng K
  Title
Multiple Roles of HIV-1 Capsid during the Virus Replication Cycle.
  Journal
Virol Sin 34:119-134 (2019)
DOI:10.1007/s12250-019-00095-3
Reference
  Authors
Rawle DJ, Harrich D
  Title
Toward the "unravelling" of HIV: Host cell factors involved in HIV-1 core uncoating.
  Journal
PLoS Pathog 14:e1007270 (2018)
DOI:10.1371/journal.ppat.1007270
Reference
  Authors
Le Sage V, Mouland AJ, Valiente-Echeverria F
  Title
Roles of HIV-1 capsid in viral replication and immune evasion.
  Journal
Virus Res 193:116-29 (2014)
DOI:10.1016/j.virusres.2014.07.010
Reference
  Authors
Murphy RE, Saad JS
  Title
The Interplay between HIV-1 Gag Binding to the Plasma Membrane and Env Incorporation.
  Journal
Viruses 12:E548 (2020)
DOI:10.3390/v12050548
Reference
  Authors
He N, Zhou Q
  Title
New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC).
  Journal
J Neuroimmune Pharmacol 6:260-8 (2011)
DOI:10.1007/s11481-011-9267-6
Reference
  Authors
Pincetic A, Leis J
  Title
The Mechanism of Budding of Retroviruses From Cell Membranes.
  Journal
Adv Virol 2009:6239691-6239699 (2009)
DOI:10.1155/2009/623969
Reference
  Authors
Kleinpeter AB, Freed EO
  Title
HIV-1 Maturation: Lessons Learned from Inhibitors.
  Journal
Viruses 12:E940 (2020)
DOI:10.3390/v12090940
Reference
  Authors
Young TM, Wang Q, Pe'ery T, Mathews MB
  Title
The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.
  Journal
Mol Cell Biol 23:6373-84 (2003)
DOI:10.1128/MCB.23.18.6373-6384.2003
Related
pathway
mmu03013  Nucleocytoplasmic transport
mmu04144  Endocytosis
KO pathway
ko03250   
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