Mus musculus (house mouse): 105988
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Entry
105988 CDS
T01002
Symbol
Espl1, AL024103, AU045071, Cerp, ESP1, PRCE, SSE
Name
(RefSeq) extra spindle pole bodies 1, separase
KO
K02365
separase [EC:
3.4.22.49
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04110
Cell cycle
mmu04114
Oocyte meiosis
mmu05166
Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
105988 (Espl1)
04114 Oocyte meiosis
105988 (Espl1)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
105988 (Espl1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mmu01002
]
105988 (Espl1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmu03036
]
105988 (Espl1)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.49 separase
105988 (Espl1)
Peptidases and inhibitors [BR:
mmu01002
]
Cysteine peptidases
Family C50: separase family
105988 (Espl1)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Sister chromatid separation proteins
Separase
105988 (Espl1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_C50
CHAT
Motif
Other DBs
NCBI-GeneID:
105988
NCBI-ProteinID:
NP_001014976
MGI:
2146156
Ensembl:
ENSMUSG00000058290
UniProt:
P60330
LinkDB
All DBs
Position
15:102204688..102232792
Genome browser
AA seq
2118 aa
AA seq
DB search
MRNFKGVNFATLLCSKEETQQLLPDLKEFLSRSRTDFPSSRTDAERRQICDTILRACTQQ
LTAKLDCPGHLRSILDLAELACDGYLLSTPQRPPLYLERILFILLRNGSTQGSPDTVLRL
AQPLHACLVQNSGEAAPQDYEAVTRGSFSLFWKGAEALLERRAAFSTRLNALSFLVLLED
GSVPCEVPHFASPTACRLVAAYQLYDATGQGLDEADADFLYEVLSRHLIRVLVGEGGSSP
GPLSPQRALCLLEITLEHCRRLCWNHHHRQAARAVERARNHLEKTSVAPSLQLCQMGVEL
LEAVEERPGAVAQLLRKAAAVLINSIEAPSPPLRALYDSCQFFLSGLERGIRRHCGLDAI
LSLFAFLGGYSSLVRHLREVSEASSKQQQCLLQMHFQGFHLFTGIVYDFAQGCQATELAQ
LVDGCRSAAVWMLEALEGLSGGELADYLSMTASYTSNLAYSFFSQKLYEEACVISEPVCQ
HLGSATSGACPEVPPEKLHRCFRLHVESLKKLGKQAQGCKMVTLWLAALKPYSLEHMVEP
VTFWVRVKMDASRAGDKELQLQTLRDSLSCWDPETQSLLLREELRAYKSVRADTGQERFN
IICDLLELSPEETAAGAWARATYLVELAQVLCYHNFTQQTNCSALDAVQEALQLLESVSP
EAQEQDRLLDDKAQALLWLYICTLEAKMQEGIERDRRAQAPSNLEEFEVNDLNYEDKLQE
DRFLYSSIAFNLAADAAQSKCLDQALTLWKEVLTKGRAPAVRCLQQTAASLQILAAVYQL
VAKPLQALETLLLLQIVSKRLQDHAKAASSSCQLTQLLLNLGCPSYAQLYLEEAESSLRS
LDQTSDACQLLSLTCALLGSQLCWACQKVTAGVSLLLSVLRDPALQKSSKAWYLLRVQAL
QVLAFYLSLSSNLLSSALREQLWDQGWQTPETALIDAHKLLRSIIILLMGSDVLSIQKAA
TESPFLDYGENLVQKWQVLTEVLTCSERLVGRLGRLGNVSEAKAFCLEALKLTTKLQIPR
QCALFLVLKGELELARGDIDLCQSDLQQVLFLLESSTEFGVVTQHPDSVKKVHTQKGKHK
AQGPCFPPLSEEEPFLKGPALELVDTVLNEPGPIQSSVNSSPVLKTKPPPNPGFLSHLPS
CDCLLCASPALSAVCLRWVLVTAGVRLATGHKAQGLDLLQAVLTRCPAATKRFTQSLQAS
LNHRTTPSCVPSLFDEIMAQVYTHLALEFLNQTSEKSLGKVLASGLKFVATRIQSLEIWR
AHLLLVQALAKLAHFSCCTSELFASSWGWHPPLVKSLPVLEPAKIRRQKCSGRGRRRIAS
VPPPLHNSSQKGLEEEGPPCTPKPPGRARQAGPRVPFTIFEEVHPTKSKLQVPLAPRVHR
RAQTRLKVIFSDDSDLEDLVSADTQLVEEPKRRGTASRTRGQTRKGRSLKTDAVVAIEST
PGHSSVSGRTRRARKVASRNCEEESPKAPLCVWASQGPEIMRSIPEEEPVDNHLEKSFEI
LRGSDGEDSASGEKAAAADTGLPVGECEVLRRDSSKAERPVLYSDTEANSDPSPWLPPFS
VPAPIDLSTLDSISDSLSIAFRGVSHCPPSGLYAHLCRFLALCLGHRDPYATAFLVAESI
SITCRHQLLTHLHRQLSKAQKQQESPELAEHLQRLDLKERPGGVPLARIQRLFSFKALGS
GCFPQAEKESFQERLALIPSGVTVCVLALATLQPGTLSNTLLLTRLEKDNPPITVKIPTA
QNKLPLSAVLKEFDAIQKDQKENSSCTEKRVWWTGRLALDQRMEALITALEEQVLGCWRG
LLLPCSADPSLAQEASKLQELLRECGWEYPDSTLLKVILSGARILTSQDVQALACGLCPA
QPDRAQVLLSEAVGQVQSQEAPRSQHLVLVLDKDLQKLPWESTPILQAQPVTRLPSFRFL
LSYTVTKEAGASSVLSQGVDPQNTFYVLNPHSNLSSTEERFRASFSSETGWKGVIGEVPS
LDQVQAALTERDLYIYAGHGAGARFLDGQAVLRLSCRAVALLFGCSSAALAVHGNLEGAG
IVLKYIMAGCPLFLGNLWDVTDRDIDRYTEALLQGWLGAGPGAPFLYYASQARQAPRLKY
LIGAAPVAYGLPISLQTP
NT seq
6357 nt
NT seq
+upstream
nt +downstream
nt
atgaggaacttcaaaggagtcaacttcgccactctgctctgcagcaaggaggagacccag
cagctgctgcctgacttgaaggagttcctgtccagatcccggactgatttccccagcagc
cgaacagatgccgaaagaagacaaatttgcgataccatcctgagggcttgcacccagcag
ttgactgccaagctcgattgccctgggcacctgaggagtattttggacctggcagagctg
gcctgtgatggctatttgttgtctactccacagcgccctcccctctacctggaacgcatt
ctcttcatcctacttcgcaatggttccactcagggaagcccagacactgtgctgcgcctt
gcccagcctctccatgcctgcttggttcagaactctggagaggctgcccctcaggactat
gaggccgtgacccggggcagcttctctctgttttggaagggagcagaggcactgttggag
cggcgagctgcgttctcaactcggctgaatgccttgagcttcttggtgctcttggaggat
ggcagtgtcccctgtgaggtccctcactttgcttctccaaccgcctgtcgtttagttgcc
gcctatcagctgtacgatgctacaggacaaggtctagatgaagctgatgccgacttcctg
tatgaagtgctttctaggcacctgatcagagtcttagtaggtgagggtggtagctctccc
ggtcctctctcgcctcagagggccctctgcctcttggaaatcaccctggaacactgccgt
cggctctgctggaaccaccaccaccgccaggctgccagagcagtggagagggctcgtaat
cacctagagaagaccagtgtagctcctagcctccagttatgccagatgggggttgagctg
ttggaagctgtagaagaaagaccaggggcagtggcccagcttctgaggaaggcagcagcc
gttcttatcaacagtatcgaggcgccgtcgcccccgctccgggcattgtacgacagctgc
cagttcttcctttcaggcctggagagaggcatcaggaggcactgtggacttgatgccata
ttgagtctctttgcttttcttgggggatacagctcccttgtccggcacctgagagaagtc
tctgaagcatcttccaagcagcagcagtgcttgcttcagatgcacttccagggtttccac
ctcttcaccgggattgtgtatgactttgctcaaggctgtcaggcaactgagcttgctcag
ctagtggacggttgcagatctgctgctgtctggatgttggaggccttagagggcctgtcg
ggtggagagctggctgactacctgagcatgactgcctcttacaccagcaacttggcctac
agcttctttagtcagaagctctatgaggaggcctgcgtcatctcagagccagtctgtcag
cacttgggctcggcaacgtcgggtgcttgtcctgaagtgcctcctgagaagctacatagg
tgcttcaggctgcatgtggagagtttgaagaaactgggtaaacaggcccagggctgcaag
atggtgaccttatggctggcagctctgaaaccctacagtctggaacacatggtcgagcca
gtcactttctgggttcgagtcaaaatggatgcatccagggcaggagacaaggagctacaa
cttcagactttgcgagacagcctaagctgctgggacccagagacacagtctctgcttctc
agggaggagctgcgggcctacaagtcagtacgggctgacactgggcaggagcgcttcaac
atcatctgtgatctgctcgagctgagccctgaagagacagcagctggagcctgggcacga
gctacctacctggtggaactggcccaagtgctgtgctaccacaactttacccagcagacc
aactgctctgccttggatgctgtccaggaagccctgcagcttctggagtccgtgagtcct
gaggcccaggagcaggatcgacttctggatgataaagcacaggccttgttatggctttac
atctgtaccttagaggccaagatgcaggaaggtattgagcgggatcggagagcccaggcc
cctagtaacttggaggaatttgaagtcaatgacctgaactatgaagataaactgcaggaa
gatcgttttctgtatagtagcattgccttcaatctggctgctgatgcagctcagtccaaa
tgcctggaccaggccctgactctgtggaaagaagtgctcaccaaggggcgagccccagct
gtgcggtgtctccagcagactgcagcctccctgcaaatcctagcggccgtctatcagttg
gtggcaaagcccttgcaggctctggagaccctcctgctcctgcagattgtatctaagaga
ctgcaggaccacgcaaaggcagccagctcttcctgccagcttacccagctactcttgaac
cttggctgtcccagctatgcgcagttgtatctggaagaggcggagtcaagcctgaggagc
ctggaccagacaagtgacgcgtgccagctgctgtccctgacctgtgctctgcttggaagt
cagctctgctgggcttgccagaaggtaactgcaggcgtttctttgttgctttctgtgctt
cgggatcctgccctccagaagtcatctaaggcttggtacttgctacgtgtccaggccctg
caagttctggctttttacctcagtctctcgtccaacctcctctcaagtgccctgcgtgag
cagctctgggatcaaggctggcagaccccggagacggcgctgattgatgcccacaagctc
ctcagaagcatcatcattctgctcatgggaagtgatgtgctctccattcagaaagcagcc
accgagtcgccctttctggactacggtgagaatctggtgcaaaaatggcaggttctcaca
gaggtgctgacctgctcggagaggctggtcggccgcctgggtcgcctggggaacgtgagt
gaggccaaggccttttgcttggaggccctaaaacttacgactaagctgcagatacctcga
cagtgtgccctgttccttgtactgaagggtgagctggagctggcccggggtgacattgac
ctctgtcagtcagacttgcagcaggttctcttcttgctcgagtcttccacagagtttggt
gttgtgacccagcatccagactcagtgaagaaggtgcacacgcagaaagggaagcataag
gctcaaggcccatgtttcccacccctgtcagaggaggagcccttcctgaaaggtcctgcc
cttgagctggtggacactgtgctcaacgaacctggtcccatccagtcctctgtaaactcc
tccccagtcctgaaaaccaagccaccacccaaccctggcttcctgtctcacttgcccagc
tgtgactgcttactgtgtgccagccctgccctctcagcagtctgtctgcgctgggtgctg
gtcactgccggagtgaggctggccaccggtcacaaagctcagggtctggatctgctgcaa
gctgtgctgacgcgttgccctgcagccaccaagcgcttcacacagagtctccaagcttct
ctgaatcacagaacaaccccctcttgtgttcccagcctctttgatgagatcatggctcaa
gtgtacacgcacttggcattggagttcctgaatcagacatctgaaaagagcctggggaag
gtcctggcgtcggggctgaagtttgtggcaacacggatacagagcttggagatctggaga
gcccacctgctcttggttcaggcccttgcaaagctggcccacttcagctgctgtacttcc
gaactctttgcaagctcctggggctggcacccaccattagtaaaaagtctgccagtctta
gagcctgctaaaattcggagacaaaaatgctctggacggggccgccggcggatagcctct
gttcccccacccctccataacagctctcagaaaggtctggaagaggaagggccaccttgt
acccctaagcctccaggtcgggctaggcaagctggccctcgtgtccctttcaccatattt
gaagaagtccaccccaccaagagcaagctccaggttcccttggctcccagggtccacagg
cgggcccagactcgcctcaaggtgatcttcagtgatgacagtgacctggaagaccttgtc
tcagctgacacacaacttgtagaggagcctaagaggcgagggactgcttcccgtacccgg
ggccaaactaggaagggacgtagcttaaagacagatgcggtggttgctatagaaagtacc
cctggacattccagtgtcagtgggaggactcggagggccaggaaggtggcttcaagaaat
tgtgaagaagagagtcccaaagcacccctctgtgtctgggccagccagggacccgagatc
atgagaagtatccctgaagaggagccagtggacaaccatctggaaaaaagcttcgagatt
ctcaggggttctgatggggaagactcggcctcaggtgagaaggcggcagctgcagacact
ggtctacccgtaggagagtgtgaggtgttgagacgggactccagcaaggcagagagacct
gtcttgtactcagacacggaggccaatagtgaccctagtccttggctcccacccttctca
gttcctgcacccattgatctttctaccctggattccatttctgactcattgagcattgct
ttccgtggtgttagtcactgccctccaagtgggctctatgctcacctctgccgcttcttg
gccctgtgtctgggccaccgagatccttatgccactgcgttccttgttgctgagtctatc
tccatcacctgccgtcaccagctgctcacccacttgcaccgacagctcagcaaggcccag
aagcagcaagaatcacctgaactggcagagcatctgcagaggctggacctgaaggagagg
cccggaggtgtcccactggcccgtatccagcgcctcttttcctttaaggctttgggatct
ggctgcttcccccaggcagagaaggagagtttccaggagcgcctggctctgatccctagt
ggggtgactgtctgtgtgttggctctggccaccctccagcctggaaccttgagcaacact
cttttactgacccgcctggaaaaggacaaccccccaattactgtgaagatccccactgcc
caaaataagctccctctaagcgcagtgctgaaagagtttgatgccatccagaaggaccaa
aaagaaaacagcagctgtactgagaaacgagtatggtggacgggccggctggcactggac
caaaggatggaggcactcatcaccgccctggaggaacaggtgctgggctgctggaggggg
ctgctgctgccatgcagtgctgaccccagccttgcccaggaggcctccaaactacaagag
ctgctgcgggaatgtggctgggaatatcctgactccactctcctgaaagtcatccttagt
ggggccagaatcctcaccagccaggatgttcaggccttggcgtgtgggctgtgcccagcc
cagcctgaccgagcccaagtgctcctgagcgaggcagtaggacaggttcagagccaggag
gcccctcgaagtcaacatcttgtattggtgttagacaaggacctgcaaaagctgccttgg
gaaagcacgcccatcctccaagcacagccggtcacccggctgccctccttccgcttcctg
ctcagctacacagtcactaaagaggctggagcctcatcagtgctgagccaaggtgttgat
ccacagaataccttctatgtgctaaaccctcacagtaacctgtcgagcacagaggagaga
tttcgagccagttttagcagtgaaactggctggaaaggagtgattggggaagtgccaagc
ctcgatcaggtgcaggctgccctgacagagcgggatttatatatctacgcagggcacgga
gccggtgcccgcttccttgatgggcaggctgtcctgcggctgagctgccgggcggtggcc
ctgctgttcggctgcagcagtgcagcccttgccgtgcatggaaacctggagggagctggt
atcgtgctcaagtacatcatggctggctgccccttgtttctaggtaatctctgggatgtg
actgaccgtgacattgaccgttacacagaggctttgctgcagggctggctgggagcaggc
ccaggggctccctttctctactatgccagccaagcccgccaggcccctcgactcaagtac
ctcattggtgctgcacctgtagcctacggcctacctatctctctgcagacaccctga
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integrated database retrieval system
