Mus musculus (house mouse): 107585
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Entry
107585 CDS
T01002
Symbol
Dio3
Name
(RefSeq) deiodinase, iodothyronine type III
KO
K07754
thyroxine 5-deiodinase [EC:
1.21.99.3
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04919
Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
107585 (Dio3)
Enzymes [BR:
mmu01000
]
1. Oxidoreductases
1.21 Catalysing the reaction X-H + Y-H = X-Y
1.21.99 With unknown physiological acceptors
1.21.99.3 thyroxine 5-deiodinase
107585 (Dio3)
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Motif
Pfam:
T4_deiodinase
AhpC-TSA
Redoxin
Motif
Other DBs
NCBI-GeneID:
107585
NCBI-ProteinID:
NP_742117
MGI:
1306782
Ensembl:
ENSMUSG00000075707
UniProt:
Q91ZI8
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:110245664..110247531
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AA seq
304 aa
AA seq
DB search
MPRQAASRLVVGEGEGPPGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLW
LLDFLCIRKHFLRRRHPDHPEPEVELNSEGEEMPPDDPPICVSDDNRLCTLASLKAVWHG
QKLDFFKQAHEGGPAPNSEVVRPDGFQSQRILDYAQGTRPLVLNFGSCTUPPFMARMSAF
QRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYVIPQHRSLEDRVSAARVLQQGAPGCA
LVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGTR
PHRF
NT seq
915 nt
NT seq
+upstream
nt +downstream
nt
atgcctcgccaggccgcctcgaggttggtggtcggagaaggtgaagggcccccgggggct
tcggggcccgcggccaccatgctccgctctctgctgcttcactcgctgaggctctgcgcc
cagaccgcctcgtgcctcgtgctgttcccgcgcttcctaggcacggccttcatgctctgg
cttttagatttcttgtgcatccgcaagcatttcctgcgccgtcgccatcctgaccaccct
gagcccgaagtagagctcaacagtgaaggcgaggagatgccccctgacgacccgcccata
tgcgtatcagacgacaaccgtctgtgcaccctggcctctctcaaagccgtgtggcatggc
cagaaattggatttcttcaagcaagcccatgagggtggcccagcgcccaactcggaggtt
gtccgacctgatggcttccagagccagcgcatcctcgactacgcacaagggacccgcccg
ttggtgctcaattttggcagctgtacctgaccaccgttcatggcgcggatgagcgccttc
cagcgcctggtcaccaagtaccagcgcgacgttgacttccttatcatctacatcgaggaa
gcccacccatccgacggctgggtcaccacagattcaccctatgtcatcccccagcaccgc
agcctggaggaccgtgtcagcgcagcgagagtactacaacaaggtgcacctggctgtgct
ctggtcctggacactatggccaactctagcagttccgcatatggtgcctattttgagcgc
ctctacgtcatccagagtggcaccatcatgtaccagggaggccgtggccccgacggttac
caggtgtctgagttgcgcacttggttggagcgctatgatgaacagttgcatggtactagg
ccacatcgattctaa
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