KEGG   Mus musculus (house mouse): 108037
Entry
108037            CDS       T01002                                 
Symbol
Shmt2, 2700043D08Rik, SHMT
Name
(RefSeq) serine hydroxymethyltransferase 2 (mitochondrial)
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00260  Glycine, serine and threonine metabolism
mmu00630  Glyoxylate and dicarboxylate metabolism
mmu00670  One carbon pool by folate
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu01230  Biosynthesis of amino acids
mmu01240  Biosynthesis of cofactors
mmu01523  Antifolate resistance
mmu04981  Folate transport and metabolism
Module
mmu_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    108037 (Shmt2)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    108037 (Shmt2)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    108037 (Shmt2)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    108037 (Shmt2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    108037 (Shmt2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     108037 (Shmt2)
SSDB
Motif
Pfam: SHMT
Other DBs
NCBI-GeneID: 108037
NCBI-ProteinID: NP_082506
MGI: 1277989
Ensembl: ENSMUSG00000025403
UniProt: Q9CZN7
LinkDB
Position
10:complement(127352992..127358313)
AA seq 504 aa
MVSFSLLRTTRPLQRCGQLVCMAARAQHSKVAQTQAGEAAGGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVRAHLLADMAHISGLVAAKVIPSPFKYADVVTTTTHKTLRGARSGLIFYRKGVRTVD
PKTGKEIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLRNAQA
MADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKTAKLQDFKSFLLKDPETSQ
RLANLRQQVEQFARGFPMPGFDER
NT seq 1515 nt   +upstreamnt  +downstreamnt
atggtatccttctctttgcttcggaccactcggcctctgcagagatgtggtcagctggtc
tgcatggctgcccgggcccagcacagcaaggtggcccagacgcaggctggggaagcagct
ggaggttggacgggccaggagagtttatcagacagtgaccctgagatgtgggagcttctg
cagagggagaaggacagacagtgtcgcggcctggagctcatcgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctcaacaacaagtactcggagggttac
cctggcaagagatactacggaggagcggaagtggtggacgagatcgagctgctctgccag
cgccgggccttggaagcctttgacctggatccggcacagtggggagtcaatgtgcagcca
tactcagggtccccagccaatctggctgcctatacggcccttctgcagcctcatgatcga
atcatggggttggacctgcccgatgggggccatctcacccatggctacatgtctgatgtc
aagcggatctccgccacatccattttcttcgagtctatgccctataagctcaatccccaa
actggcctcatcgactacgaccagctggcgctgaccgctcggcttttccgaccgcggctc
atcatagctggcacgagtgcctatgcccgcctcattgactatgcacgcatgagagaggtc
tgtgatgaggtcagggcacacctgctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcccctttcaagtacgcggatgttgttaccaccaccactcacaag
acactgcgaggggccaggtcagggctcatcttctaccggaagggagtacgaaccgtagac
cccaagactggcaaagagatcccttatacctttgaggaccgaatcaacttcgctgtgttc
ccatccctacagggtggcccccacaaccacgccattgctgcagtagccgtggctctcaag
caggcctgcacccctatgttccgcgagtactccttacaagtgctgaggaacgcccaggcc
atggctgatgccctgctcaagcgaggatactcgctggtgtctggtggcactgacacccac
ctggtgctggtggacctgcggcccaagggcctggatggagcccgagccgaacgcgtgttg
gaactcgtctccatcacagccaacaagaacacctgtcctggagaccggagcgccattact
ccggggggcttgaggcttggggcccccgcgttgacctctcgccagttccgtgaggacgac
ttccgtagagtcgtcgattttatcgatgagggagtcaacattggcttggaggtgaagcgc
aagactgccaagctccaggatttcaaatccttcctgctcaaagacccagagacaagccag
cgtttggccaacctccggcaacaggtggaacagtttgccaggggcttccccatgcctgga
tttgatgaacgttga

KEGG   Mus musculus (house mouse): 20425
Entry
20425             CDS       T01002                                 
Symbol
Shmt1, Shmt, mshmt, mshmt1, mshmt2
Name
(RefSeq) serine hydroxymethyltransferase 1 (soluble)
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00260  Glycine, serine and threonine metabolism
mmu00630  Glyoxylate and dicarboxylate metabolism
mmu00670  One carbon pool by folate
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu01230  Biosynthesis of amino acids
mmu01240  Biosynthesis of cofactors
mmu01523  Antifolate resistance
mmu04981  Folate transport and metabolism
Module
mmu_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    20425 (Shmt1)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    20425 (Shmt1)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    20425 (Shmt1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    20425 (Shmt1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    20425 (Shmt1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     20425 (Shmt1)
SSDB
Motif
Pfam: SHMT Aminotran_1_2
Other DBs
NCBI-GeneID: 20425
NCBI-ProteinID: NP_033197
MGI: 98299
Ensembl: ENSMUSG00000020534
UniProt: P50431
Structure
LinkDB
Position
11:complement(60679723..60702062)
AA seq 478 aa
MADRDATLWASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALG
SCLNNKYSEGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFA
VYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQL
EENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFE
HCHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHN
HAIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSK
GTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIH
RGIELTLQIQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPGLPDF
NT seq 1437 nt   +upstreamnt  +downstreamnt
atggcagacagggatgccaccctgtgggcttctcatgagaagatgttgtcgcagcccctc
aaggacagtgatgccgaggtttacagcatcattaaaaaggagagcaaccggcagagggtc
ggattagagctgattgcctcggagaattttgccagccgagctgtgttggaggccctggga
tcttgcttaaataacaaatactctgagggatatccaggccaaaggtattatggcgggacc
gagttcatcgatgagctggagatgctgtgtcagaagcgtgcattacaggcctaccatctg
gatcctcagtgctggggtgtcaatgtccagccttattcaggctcccctgcaaactttgct
gtgtatactgccctggtagagcctcatgggcgaatcatgggcttggacctgccagacggt
ggccatctgacccatggcttcatgacagacaagaagaaaatctctgccacatctatcttc
tttgaatccatgccttataaggtgtacccagagactgggtacatcaactatgaccagctg
gaggagaatgccagcctcttccacccgaagctgatcatcgcagggaccagctgctactcc
cggaacctggactacgcacggctgcggaagattgcggatgataatggggcgtatctcatg
gcagacatggcacatatcagtgggctcgtggcagctggggtggtgccctccccctttgaa
cactgccatgtagtgaccactacaacccacaagaccctgagaggctgccgtgctggtatg
atattctacagaaagggtgtgcgcagtgtggatcccaagactggcaaagagacttactat
gaactggagtccctcatcaactctgccgtgttcccaggccttcaggggggtcctcacaac
catgccattgctggtgttgctgtggccctgaagcaagccatgactacagaattcaaaatc
taccagctccaggtgttggccaactgcagggctctgtctgatgcactcacagagctaggc
tacaaaatagtcacaggtggctctgataatcacttgatcctaatggatctgcgttctaag
ggtactgatggtggaagggctgagaaggtactagaagcctgttctatcgcctgcaacaag
aatacctgcccaggtgacaagagcgcgttacggcccagtggactgcgactggggactcca
gcattgacatcccgaggacttttggaagaagacttccaaaaagtagcacactttatccac
agggggatagagttgacactgcagattcagagccacatggccacgaaggccacactgaaa
gagttcaaagagaagctggcaggagatgagaagatccagagtgctgtggcaactctccgg
gaagaagtggagaactttgcttccaacttctcactacctggccttcctgacttctga

DBGET integrated database retrieval system