KEGG   Mus musculus (house mouse): 110385
Entry
110385            CDS       T01002                                 
Symbol
Pde4c, Dpde1, E130301F19Rik, dunce
Name
(RefSeq) phosphodiesterase 4C, cAMP specific
  KO
K13293  cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04024  cAMP signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    110385 (Pde4c)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    110385 (Pde4c)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    110385 (Pde4c)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    110385 (Pde4c)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     110385 (Pde4c)
SSDB
Motif
Pfam: PDEase_I PDE4_UCR Emfourin
Other DBs
NCBI-GeneID: 110385
NCBI-ProteinID: NP_001297394
MGI: 99556
Ensembl: ENSMUSG00000031842
UniProt: Q3UEI1
LinkDB
Position
8:71176485..71203835
AA seq 686 aa
MRRSGTALSFLWTERVREPVDSGVAPVSPLGGGVILRRFSGTLLLPPLSSRLGSSGEAES
AAHVVFTIGTQGTQRNLGSAQSSFDLENGLPGGKGLLDAQSGPSLGRALQPPVHHVQRRE
SFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRNNVAALAHGPGS
ATRQVLLGTPPHSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFK
RMLNRELSYLSETSRSGNQVSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSH
TSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDL
LKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVL
AAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRN
LSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQ
SLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVG
FIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSPPHTMGSDRFKFELTLEE
AEEEEEEEDEGQCTALNRESSELPST
NT seq 2061 nt   +upstreamnt  +downstreamnt
atgaggcggagtggcacggccctgtccttcctgtggactgagcgagtccgagagccagtg
gattctggagtggcccctgtcagccccctaggtgggggtgtgatcctgagacggttctca
gggaccctgctgctgcctccactgtccagccgcctggggtcctctggggaggcggagtct
gctgcccacgtggtcttcacaattggaactcaagggacacagagaaaccttggctcagct
cagagcagctttgacctcgaaaatgggcttccgggcggcaagggtctcctagacgctcag
tccgggccgagtctcggccgcgccctccagccccctgtccatcatgtccagcggcgcgag
tccttcctgtaccgttcggacagcgaccatgaaccttcacccaaggctgtgtcccggacc
tcctcggcggccagtgacctacatggagaagacatgattgtcacgcccttcgcccaggtc
ctggccagtctcaggacggtccgtaacaacgtggctgcccttgcacatggcccgggtagt
gccaccaggcaggtgctcctgggaacccctccgcacagcagtcaacaggcagccccaaca
gaggactctgggctgcagctggtgcaggagaccctggaggagctggactggtgcctggag
cagctggagacactgcagactcgtcgctcagtgggcgagatggcctccaacaagttcaag
cgcatgctcaaccgtgagttgtcttacctgtcggaaaccagccgctcagggaaccaggtg
tcggagtacatctcgcagactttcctggaccaacaggctgaggttgagctgcctcagccg
cccacggaagacgacccatggcccatggcccagatcactgagctgcgtaggtcctcccac
accagccttcccacagctgctatcccacgctttggggtccagacagatcaggaggagcag
ctggctaaggagcttgaagacaccaacaaatggggacttgatgtgttcaaagtggctgag
ctgagtgggaaccggcctctcacagctgtcatattcagcgtcttccaggaacgagacctc
ctcaagacgttccagatcccagcagacacgctgctggcgtacttgctgacactagagggg
cactaccactccgacgtggcgtaccacaacagcatgcatgctgccgatgtggtgcagtcc
gcacacgtgttgctgggcaccccagccctggaggctgtgttcacggacctagaagtcttg
gcagctatctttgcatgtgctatacacgacgtagaccacccgggggtctccaaccagttt
ctcatcaacaccaactcagagctggcactgatgtacaatgattcatcggtgctggagaac
catcacctcgcggtaggcttcaagctcctgcagggggaaaactgcgacatcttccggaac
ctcagtaccaagcagagactgagtctgcgcaggatggtcatagacatggtgctggccaca
gatatgtctaagcacatgagccttctggccgacctcaagaccatggtggagacgaagaaa
gtgaccagccttggcgtcctgctcttggacaactactctgaccgcatccaggttctccag
agcctggtgcactgcgctgacctcagcaaccccgccaagccgctacccctctaccgccag
tggacggagcgcatcatggccgagttcttccagcagggtgaccgggagcgagagtcgggt
ctggacatcagccccatgtgcgacaaacacacagcctcgatggagaaatcccaggtggga
ttcattgactacatcgctcagccattgtgggagacatgggctgacctagtgcaccccgat
gctcaggagcttctggacaccttggaagacaacagagagtggtatcagagtaggattccc
tgcagccctccacacaccatgggctcggacaggttcaagtttgagctgaccctggaggaa
gcagaggaagaggaggaagaggaggatgaagggcagtgcacagcactgaacagggagtcc
tcagagttacccagcacttaa

KEGG   Mus musculus (house mouse): 18573
Entry
18573             CDS       T01002                                 
Symbol
Pde1a
Name
(RefSeq) phosphodiesterase 1A, calmodulin-dependent
  KO
K13755  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04740  Olfactory transduction
mmu04742  Taste transduction
mmu04924  Renin secretion
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18573 (Pde1a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    18573 (Pde1a)
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    18573 (Pde1a)
  09157 Sensory system
   04740 Olfactory transduction
    18573 (Pde1a)
   04742 Taste transduction
    18573 (Pde1a)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18573 (Pde1a)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     18573 (Pde1a)
SSDB
Motif
Pfam: PDEase_I PDEase_I_N
Other DBs
NCBI-GeneID: 18573
NCBI-ProteinID: NP_001153054
MGI: 1201792
Ensembl: ENSMUSG00000059173
UniProt: Q61481
LinkDB
Position
2:complement(79664797..80026862)
AA seq 545 aa
MGSTDTDIEELENATYKYLIGEQTEKMWQRLKGILRCLVKQLEKGDVNVVDLKKNIEYAA
SVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMMKKKPEEKPKFRS
IVHAVQAGIFVERMYRKNYHMVGLTYPAAVIVTLKEVDKWSFDVFALNEASGEHSLKFMI
YELFTRYDLINRFKIPVSCLIAFAEALEVGYSKHKNPYHNLVHAADVTQTVHYIMLHTGI
MHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLM
QEEEMNILVNLSKDDWRDLRNLVIEMVLATDMSGHFQQIKNIRNSLQQPEGIDRAKTMSL
ILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGF
IDFIVEPTFSLLTDSTEKIVIPLIEEASKSQSSNYGASSSSTMIGFHVADSLRRSNTKGS
VCDGSYAPDYSLSAVDLKSFKNNLVDIIQQNKERWKELAAQGELDLHKNSEELGNTEEKH
ADTRP
NT seq 1638 nt   +upstreamnt  +downstreamnt
atggggtctactgatacggacatcgaagaattggaaaacgccacttacaagtatctcatt
ggagaacagaccgagaagatgtggcagcgcctgaagggaatactaagatgcttagtgaag
cagctggagaaaggtgatgtcaacgttgttgacctaaagaagaatatcgaatatgcagca
tcagtactggaagctgtttacatcgatgagacaagaagactgctggacacagaggatgaa
ctcagcgacatccagactgactccgtcccatcggaagtccgggattggttggcttcaact
ttcacacgcaaaatggggatgatgaaaaagaagcctgaagaaaaaccaaagtttcgcagc
attgtccatgctgtccaggctgggatttttgtggaaaggatgtacaggaagaactatcac
atggttggtttgacatatcctgcagctgtcatagtgacactcaaggaagttgataaatgg
tcttttgatgtatttgccttaaatgaagcaagcggggagcatagcctgaagtttatgatt
tatgaactctttaccagatatgatcttatcaaccgcttcaagattcctgtttcttgccta
attgcctttgcagaagccttagaagttggttacagcaagcacaaaaatccatatcataat
ttggtccatgcagctgacgtcactcaaactgtgcattatataatgcttcatacaggtatc
atgcactggctcactgaactggaaattttagccatggtctttgcagctgccattcatgat
tatgagcacacaggaacaacaaacaacttccatattcagacgaggtcggacgttgctatt
ctgtacaacgaccgctcagtgcttgagaatcaccacgtcagcgcagcctacagacttatg
caagaggaggaaatgaatattttggtaaatttgtctaaagatgactggagggatcttcgg
aacttagtgattgaaatggtcttagcgacagacatgtcagggcattttcagcaaattaaa
aacataagaaacagcttgcagcagccggaagggattgacagagccaaaactatgtccctg
atactccatgcagctgacatcagccacccagccaaaacttggaagttgcactacagatgg
accatggccctaatggaggagtttttcctgcagggagacaaagaagctgaattagggctt
ccattttctccactttgtgatcggaagtcaacaatggttgcccagtcgcaaataggtttc
attgatttcatagtggagccaacgttttctctcctgacggactcaacagagaaaattgtc
attcctcttatagaggaagcttcaaagtcacagtcttcaaactacggggcaagcagctcg
tccaccatgattgggttccatgttgctgactctctgaggcggtcaaatacaaaaggctcc
gtgtgtgatgggagctatgccccagactactcgctctcagctgtggatctgaagagtttc
aaaaacaacctggtggacatcattcagcagaacaaagagaggtggaaagagttggctgcc
caaggtgaacttgatcttcataagaactcagaagagttaggaaatactgaagaaaagcat
gctgacacacgtccatag

KEGG   Mus musculus (house mouse): 18574
Entry
18574             CDS       T01002                                 
Symbol
Pde1b, Pde1b1
Name
(RefSeq) phosphodiesterase 1B, Ca2+-calmodulin dependent
  KO
K13755  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04740  Olfactory transduction
mmu04742  Taste transduction
mmu04924  Renin secretion
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18574 (Pde1b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    18574 (Pde1b)
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    18574 (Pde1b)
  09157 Sensory system
   04740 Olfactory transduction
    18574 (Pde1b)
   04742 Taste transduction
    18574 (Pde1b)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18574 (Pde1b)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     18574 (Pde1b)
SSDB
Motif
Pfam: PDEase_I PDEase_I_N
Other DBs
NCBI-GeneID: 18574
NCBI-ProteinID: NP_032826
MGI: 97523
Ensembl: ENSMUSG00000022489
UniProt: Q01065 Q6PDS5
LinkDB
Position
15:103411461..103438483
AA seq 535 aa
MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLE
YTASLLEAVYIDETRQILDTEDELRELRSDAVPSEVRDWLASTFTQQTRAKGRRAEEKPK
FRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVHNCLKNLDLWCFDVFSLNRAADDHALR
TIVFELLTRHSLISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLR
TGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVF
RMMQDDEMNIFINLTKDEFAELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKSKA
LSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQ
IGFIDFIVEPTFSVLTDVAEKSVQPLADDDSKPKSQPSFQWRQPSLDVDVGDPNPDVVSF
RATWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPSSPAEDEHNQNGNLD
NT seq 1608 nt   +upstreamnt  +downstreamnt
atggagctgtccccccgcagtcctccagagatgctggagtcggattgcccgtcacccctg
gagctgaagtcagcccccagcaagaaaatgtggattaagctacggtctctgctgcgctac
atggtgaagcagttggagaatggggaggttaacatcgaggagctgaagaaaaacctggaa
tacacagcttccctgctggaagctgtctacattgatgagacaaggcaaatcctagacact
gaagatgagcttcgggaacttcggtcagatgctgtgccttcagaggtgcgggactggttg
gcctccaccttcacccagcagacccgagccaaaggtcgcagggcagaagagaaacccaag
ttccgaagcatcgtgcatgctgtgcaggctgggatcttcgtggagcggatgttccggaga
acgtatacctctgtgggccccacatactctactgcagtccacaactgtctcaagaacctg
gacctctggtgctttgatgtcttttccttgaaccgggcagccgatgaccacgctctgagg
accattgtttttgagttgctgactcggcatagcctcatcagccgctttaagattcccaca
gtgtttctgatgagttttctggaggccttggagacaggctatgggaaatataagaatcct
taccacaaccagatccacgcagccgacgtgacccagactgtccattgcttccttctccgc
acaggcatggtgcactgcctgtcagagattgaggtcttggccatcatctttgctgcagcc
atccatgactatgagcacacaggcacaaccaacagcttccacattcagaccaagtcagaa
tgtgccatcctgtacaatgatcgatcggtgctggagaatcaccacatcagctctgtcttt
cgaatgatgcaggatgatgagatgaacatttttatcaatctcaccaaggatgaatttgca
gagctgcgggccctggttatcgagatggtgttggccacagacatgtcctgccatttccag
caagtgaagactatgaagacagcactgcagcagttggaaaggattgacaagtccaaggcc
ctatctcttctgcttcatgctgctgacatcagccacccaactaagcagtggtcagtccac
agccgctggaccaaggccctaatggaagagttcttccgccagggtgacaaggaggcagag
ctgggcctgcccttctctccactctgtgatcgcacttccacattggtggcccagtcccag
ataggtttcattgacttcattgtggagccaaccttctctgtgctgactgatgtggcagaa
aagagtgtccagcccttggcagatgatgattccaagcctaaaagtcagcccagcttccag
tggcgccagccttctttagatgtggacgtaggagaccccaaccctgatgtggtcagtttc
cgtgccacctggaccaagtacattcaagagaacaaacagaagtggaaggaacgggcagca
agtggcatcaccaaccagatgtccattgatgaactgtccccctgtgaggaagaagcccca
tcctcccctgcagaagatgagcacaaccagaatgggaatctggattag

KEGG   Mus musculus (house mouse): 18575
Entry
18575             CDS       T01002                                 
Symbol
Pde1c
Name
(RefSeq) phosphodiesterase 1C
  KO
K13755  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04740  Olfactory transduction
mmu04742  Taste transduction
mmu04924  Renin secretion
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18575 (Pde1c)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    18575 (Pde1c)
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    18575 (Pde1c)
  09157 Sensory system
   04740 Olfactory transduction
    18575 (Pde1c)
   04742 Taste transduction
    18575 (Pde1c)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18575 (Pde1c)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     18575 (Pde1c)
SSDB
Motif
Pfam: PDEase_I PDEase_I_N
Other DBs
NCBI-GeneID: 18575
NCBI-ProteinID: NP_001153425
MGI: 108413
Ensembl: ENSMUSG00000004347
UniProt: Q64338
LinkDB
Position
6:complement(56046783..56629590)
AA seq 706 aa
MESPTKEIEEFESNSLKHLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIDALKDVDTWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH
HLSAAYRLLQEDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE
AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS
TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDESSQTGGTGQRRSSLNSINSSDAKR
SGVKSSGSDGSAPINNSVIPVDYKSFKATWTEVVQINRERWRAKVPKEEKAKKEAEEKAR
LAAEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQ
NGDLKDGKNKADKKDHSNTGNESKKTDGTKKRSHGSPAPSTSSTSRITLPVIKPPLRHFK
RPAYASSSYAPSVPKKTDDHPVRYKMLDQRIKMKKIQNISHHWNKK
NT seq 2121 nt   +upstreamnt  +downstreamnt
atggagtctccaaccaaggaaattgaagaattcgagagcaactctctgaaacacctgcaa
cctgagcagatcgagaaaatctggcttcggctccgcgggctgaggaaatataagaaaacg
tcccagaggttacggtctttggtcaagcaattagaacgaggagaggcctctgtggtagac
cttaagaagaatctggaatatgcagccacagtgcttgaatctgtatatattgatgaaaca
aggcgactgctggatacagaggatgagcttagtgacattcaatcagatgctgtgccttca
gaagttcgggattggctggcctccaccttcacacggcagatggggatgatgcttaggaga
agtgatgagaagcccaggttcaagagcatcgtccatgcggtgcaagctgggatatttgtg
gaaagaatgtacagacggacatcaaacatggttgggctgagctatccaccggctgtaatc
gatgcattgaaggatgtggatacgtggtccttcgatgtcttttccctcaatgaggccagt
ggagatcatgcactgaagttcattttctatgaattactcacacgttatgacctgatcagc
cgttttaagataccgatttctgcacttgtctcatttgtggaggccctcgaagtgggttac
agcaagcacaaaaatccttaccataacctgatgcatgcagctgacgtcacacagactgtg
cattacctcctttataagacaggagtagcaaactggctgacagagctggagatctttgca
ataatcttttcggctgccatccatgactatgaacatactggaactacaaacaatttccac
attcagactcggtcagatccagctatcctgtacaatgacagatctgtcctggagaaccac
cacctgagtgcagcctaccgccttctgcaggaagacgaagagatgaatattctggttaac
ctctcaaaggatgactggagggagtttcgaactttggttattgagatggtaatggccaca
gatatgtcctgtcatttccagcaaatcaaagccatgaagacagccctgcagcaaccagaa
gcaattgagaagccgaaagccttatccctcatgttacacacagcagacatcagtcatcct
gcgaaagcatgggacctgcaccaccgctggaccatgtctctcctggaggagttctttaga
cagggtgacagagaagcagagctggggctgccattttctcctctttgtgacagaaagtca
accatggttgctcagtcacaagtgggttttattgacttcattgtggagcccaccttcact
gtgctcacggacatgaccgagaagattgtgagtccattaattgacgaaagctcccagact
ggtgggacagggcagaggagatcaagtttgaacagcatcaactcatcagatgcaaagcga
tccggtgtcaagagttctgggtcagatggaagtgctcccatcaacaattctgtcattcct
gttgactataagagttttaaagccacttggactgaggtggtgcagatcaatcgggagcgg
tggcgagccaaggtacccaaagaagaaaaagccaagaaggaagctgaagagaaggctcgc
ctggctgctgaggaaaagcaaaaggaaatggaagccaaaagccaagctgaacaaggcaca
accagcaaaggcgagaaaaagacatcaggagaagccaaaagtcaagtcaatggaacacgc
aagggtgataaccctcgtgggaagaactccaaaggagaaaaggcaggcgaaaagcagcag
aacggtgacttgaaagacggtaaaaataaggcagacaagaaggatcactccaacaccgga
aatgagtcaaagaaaacagatggtacaaagaagcgttctcatggctcacctgctccgagc
actagttccacaagtcgcattaccttgccagtcatcaagcctcctttgcgtcactttaag
cgtcctgcttatgcatctagctcctatgcaccttccgtcccgaagaaaactgatgatcat
cctgtaagatacaagatgctggatcagcggatcaagatgaaaaagatccagaacatctct
catcactggaacaaaaaatag

KEGG   Mus musculus (house mouse): 18576
Entry
18576             CDS       T01002                                 
Symbol
Pde3b, 9830102A01Rik
Name
(RefSeq) phosphodiesterase 3B, cGMP-inhibited
  KO
K13296  cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04022  cGMP-PKG signaling pathway
mmu04024  cAMP signaling pathway
mmu04371  Apelin signaling pathway
mmu04910  Insulin signaling pathway
mmu04914  Progesterone-mediated oocyte maturation
mmu04922  Glucagon signaling pathway
mmu04923  Regulation of lipolysis in adipocytes
mmu04924  Renin secretion
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18576 (Pde3b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    18576 (Pde3b)
   04024 cAMP signaling pathway
    18576 (Pde3b)
   04022 cGMP-PKG signaling pathway
    18576 (Pde3b)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    18576 (Pde3b)
   04922 Glucagon signaling pathway
    18576 (Pde3b)
   04923 Regulation of lipolysis in adipocytes
    18576 (Pde3b)
   04914 Progesterone-mediated oocyte maturation
    18576 (Pde3b)
   04924 Renin secretion
    18576 (Pde3b)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18576 (Pde3b)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     18576 (Pde3b)
SSDB
Motif
Pfam: PDEase_I
Other DBs
NCBI-GeneID: 18576
NCBI-ProteinID: NP_035185
MGI: 1333863
Ensembl: ENSMUSG00000030671
UniProt: Q61409 E9QLQ3 Q3UQ25
LinkDB
Position
7:114014388..114137173
AA seq 1099 aa
MRKDERERDAPAMRSPPPPPASAASPPESLRNGYVKSCVSPLRQDPPRSFFFHLCRFCNV
EPPAASLRAGARLSLGVLAAFVLAALLGARPERWAAAAAGLRTLLSACSLSLSPLFSIAC
AFFFLTCFLTRAQRGPGRGAGSWWLLALPACCYLGDFAAWQWWSWLRGEPAAAGRLCLVL
SCVGLLTLAPRVRLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVGGAGCLLALG
LDHFFHVRGASPPPRSASTAEEKVPVIRPRRRSSCVSLGESAAGYYGSGKMFRRPSLPCI
SREQMILWDWDLKQWCKPHYQNSGGGNGVDLSVLNEARNMVSDLLIDPSLPPQVISSLRS
ISSLMGAFSGSCRPKINSFTPFPGFYPCSEVEDPVEKGDRKLHKGLSGRTSFPTPQLRRS
SGASSLLTNEHCSRWDRSSGKRSYQELSVSSHGCHLNGPFSSNLFTIPKQRSSSVSLTHH
AGLRRAGALPSHSLLNSSSHVPVSAGSLTNRSPIGFPDTTDFLTKPNIILHRSLGSVSSA
ADFHQYLRNSDSNLCSSCGHQILKYVSTCEPDGTDHPSEKSGEEDSSVFSKEPLNIVETQ
EEETMKKACRELFLEGDSHLMEEAQQPNIDQEVSLDPMLVEDYDSLIEKMNNWNFQIFEL
VEKMGEKSGRILSQVMYTLFQDTGLLETFKIPTQEFMNYFRALENGYRDIPYHNRVHATD
VLHAVWYLTTRPIPGLPQIHNNHETETKADSDGRLGSGQIAYISSKSCCIPDMSYGCLSS
NIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLS
RPEYNFLLNLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSSEND
RLLVCQVCIKLADINGPAKDRDLHLRWTEGIVNEFYEQGDEEATLGLPISPFMDRSSPQL
AKLQESFITHIVGPLCNSYDAAGLLPGQWIETEEGDDTESDDDDDDDDGGGEELDSDDEE
TEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIEEEEEKCKAEGNKLQVDNASLPQ
ADEIQVIEEADEEEEQMFE
NT seq 3300 nt   +upstreamnt  +downstreamnt
atgaggaaagacgagcgcgagcgggacgcgccagccatgaggtccccgccgccgccgcca
gcctcggccgcctcgccccccgagagcctgcgcaacggctacgtgaagagctgcgtgagc
ccgctgcggcaggaccctccgcgcagcttcttcttccacctctgccgcttctgcaacgtg
gagccgccggcggcctcgctccgcgccggggcacgcctctcgctcggcgtcctggccgcc
tttgtcctggccgcgctgctgggcgcgaggcccgagcgctgggcggccgcggcagccggg
ctccggacgctgctgagcgcctgctcgctcagcctcagcccgctcttcagcatcgcctgt
gccttcttcttcctcacctgtttcctgacgcgcgcgcagcgcggcccgggccgcggcgcc
ggctcctggtggctgctggcgctgcccgcctgctgctacctgggcgacttcgcggcgtgg
cagtggtggtcgtggctgcgtggggagccggcggcggcgggccggctctgcctggtgctg
agctgcgtggggctgctgacgctcgcgccccgcgtgaggctgcggcacggcgtcctggtg
ctgctcttcgccggcctggtgtggtgggtgtccttctccggcctcggggctctgccgccc
gcgctcaggcctctgctgtcgtgcctggtcgggggcgcgggatgcctgctagccctgggc
ttggaccacttctttcacgtccggggagcctcccctccgccgcgctcggcgagtaccgcg
gaggaaaaagtgcctgtgatcagaccccggaggaggtccagctgcgtgtcgctgggagaa
agcgcagccggttactatggcagtggcaagatgttcaggagaccgtcgttgccttgtatt
tcccgagaacagatgatcctctgggactgggacttgaagcagtggtgtaaacctcattac
cagaattctggaggtggaaatggagttgatctttcagtgctaaatgaagctcgcaatatg
gtgtcagacctgctgattgacccaagccttcccccacaagtcatttcttctctgcggagt
atcagtagcttgatgggtgctttctcaggttcctgtaggccaaagattaattcttttaca
ccatttcctggattttatccctgctctgaagtagaagatccagttgagaaaggagatcga
aaacttcacaagggattgagtggcagaaccagtttcccaactccacagctgaggaggagc
tctggagcctcatcgttgctgactaatgagcactgttcaaggtgggatcgcagcagtggt
aagaggtcttaccaagaactcagtgtttcaagtcatggatgccacctaaatgggcctttt
agttcaaatctttttacaattccaaagcagaggtcatcgtctgtgtcactgacgcaccat
gcaggtctgagaagagctggtgctttgcccagccacagtcttctgaattcttcaagccat
gtaccagtgtctgctggctctctaactaatcgatcacccataggatttcctgataccact
gattttcttactaagccaaatattattttacatagatcactgggcagtgtatcaagtgca
gcagatttccatcagtaccttaggaactctgacagcaatctgtgtagcagctgtggacac
caaatactcaaatatgtttcaacatgtgaacccgatggtacagaccaccccagtgaaaaa
tcaggtgaagaagacagcagtgttttctcaaaagaaccattgaacattgtggaaacccaa
gaagaagagaccatgaagaaagcctgcagggagttatttttggaaggtgatagtcacctg
atggaagaggcacagcaaccaaatatcgatcaggaagtgtcactggatccaatgttagta
gaagattatgattcattaatagaaaagatgaacaactggaattttcagatttttgagctt
gtagaaaagatgggagaaaaatcaggaaggattctcagtcaggttatgtatactttattt
caagatactggtttattggaaacatttaaaattcccactcaagaatttatgaattatttt
cgtgccttagaaaatggctaccgggacattccatatcacaatcgtgtgcatgccacagat
gtcctacatgctgtttggtatttgacaacccgaccaattcctggcttacctcagatccat
aataaccatgaaacggaaaccaaagcagattcagatggtagacttggttctggacagatt
gcttacatttcttcgaagagttgctgtattccagatatgagttatggctgcctatcttca
aacatccctgcattagaattgatggctttgtatgtggcagctgccatgcacgattacgat
cacccaggaagaacaaatgcgtttctagtggctacaaatgcacctcaggcagttttatac
aatgacagatctgttctagagaatcatcatgctgcatcagcttggaatctgtatctttct
cgcccagagtacaacttcctccttaaccttgatcacatggaattcaagcggtttcgattt
ttagttatagaagcaatccttgctacagatctcaaaaaacattttgatttccttgcagaa
ttcaatgccaaggccaatgatgtaaatagtaacggtatagaatggagcagtgaaaacgat
cgcctcttggtctgccaggtgtgcatcaaattagcagatatcaatggcccagcaaaagat
cgggacctacatttgagatggacagaaggcattgtgaatgaattttatgagcagggagat
gaagaagcaaccctgggtctacctattagtcccttcatggatcgttcttctcctcaacta
gcaaaactccaagaatcttttatcacccacattgtgggccccctgtgcaactcctatgat
gctgctggcttgctgccgggtcagtggatagaaacagaagagggtgatgatacagaaagt
gatgatgatgatgatgatgatgatggtggtggtgaagaattagattcagatgatgaagaa
acagaagacaatctaaatcctaaaccacaaagaaggaaaggcaggcggcgaatattttgc
caactaatgcaccacctcactgaaaaccacaagatatggaaggaaatcatagaagaagaa
gaagaaaaatgtaaagctgaggggaacaaactgcaggtggataatgcctccttacctcag
gcagatgagattcaggttattgaagaagcagatgaagaggaagaacaaatgtttgaatga

KEGG   Mus musculus (house mouse): 18577
Entry
18577             CDS       T01002                                 
Symbol
Pde4a, D9Ertd60e, Dpde2
Name
(RefSeq) phosphodiesterase 4A, cAMP specific
  KO
K13293  cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04024  cAMP signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18577 (Pde4a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    18577 (Pde4a)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    18577 (Pde4a)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18577 (Pde4a)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     18577 (Pde4a)
SSDB
Motif
Pfam: PDEase_I PDE4_UCR Emfourin
Other DBs
NCBI-GeneID: 18577
NCBI-ProteinID: NP_899668
MGI: 99558
Ensembl: ENSMUSG00000032177
UniProt: O89084 B2RTL2 Q3TUD0
LinkDB
Position
9:21076998..21124544
AA seq 844 aa
MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERSEPERS
PHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTGGGSSRRLEAENGPTPSPGRSPLDS
QASPGLMLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVASEAHGEDLIVTPFAQVL
ASLRNVRSNFSLLTNVPIPSNKRSPLGGPPSVCKATLSEETCQQLARETLEELDWCLEQL
ETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTP
RQRPFQQPPPAAVQQAQPMSQITGLKKLVHTGSLNINVPRFGVKTDQEDLLAQELENLSK
WGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMTYMLTLEDHYHADVAYHN
SLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELAL
MYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLA
DLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFF
QQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NRDWYHSAIRQSPSPTLEEEPGVLSDPALPDKFQFELTLEEEDEEDSLEVPGLPCTEETL
LAPHDTRAQAMEQSKVKGQSPAVVEVAESLKQETASAHGAPEESAEAVGHSFSLETSILP
DLRTLSPSEEAQGLLGLPSMAAEVEAPRDHLAAMRACSACSGTSGDNSAVISAPGRWGSG
GDPA
NT seq 2535 nt   +upstreamnt  +downstreamnt
atggagcctccggccgccccctcggagaggagcctgtctctctctcttcccgggccccga
gagggccaggccaccctgaagccgcccccccagcacctgtggcggcagccgaggaccccg
atccgcatccagcagcgcggctactcggacagtgccgagcgctcagagccagagcgctcg
ccgcaccggcccatagagcgcgccgacgccgtggacactggcgaccggccaggcctgcgg
actacccgcatgtcctggccctcgtccttccacggcaccggtaccggcggaggcagcagt
aggcgcttggaggcagaaaatgggccaacaccgtcccctggccgcagccccctggactcg
caggcgagcccggggcttatgctgcatgccggggcagccaccagccagcgccgagaatcc
ttcctctatcgctcagacagcgactatgacatgtcaccgaagactatgtccaggaactca
tccgtcgccagcgaagcgcatggtgaagacctcattgtgaccccgtttgcccaggtgctg
gccagtctccgcaacgttcgaagcaacttctcactcctaaccaatgtgcccatccccagc
aacaagaggtccccgctgggcgggccaccctctgtctgcaaggccacactgtcagaggag
acatgccagcagctggcccgggagaccctggaagagctggattggtgcctggagcagctg
gagaccatgcagacctaccgctctgtcagcgagatggcctcacacaagtttaaaaggatg
ctgaaccgggaactcacacacctgtcggaaatgagcaggtcaggaaaccaggtctcagag
tacatttccaacacgttcctagacaagcagcacgaagtggagatcccatcgcccacgccg
cgacagagacccttccagcagcccccaccagcagcagtgcagcaggcccagcccatgtct
cagatcacagggctgaaaaagctggtacacaccggaagcttgaacatcaatgtcccacga
tttggagtcaagacagatcaggaggacctcttagcacaagaactggagaacttgagcaaa
tggggcctgaacatcttttgtgtgtcggagtacgctggaggccgttcactcagctgtatc
atgtatacgatattccaggagcgggacttactgaagaaattccacatccccgtggacacc
atgatgacatacatgctgacgctggaggaccactaccacgctgacgtggcctaccacaac
agcctgcacgcagccgatgtgctacagtccacacatgtgctgctggccacgcctgcactg
gatgccgtgttcacagacctggagattcttgctgctctcttcgctgctgccatccatgac
gtggaccaccctggcgtctccaaccagttcctaatcaacaccaattcggagctggcattg
atgtacaacgatgagtctgtgcttgagaaccaccacctggctgtgggattcaagctgctg
caagaagagaactgcgacatcttccagaacctcagcaagcgccagcggcagagcctgcgc
aagatggtcatcgacatggtgctggccacagacatgtccaagcacatgacccttctggct
gacctgaagactatggtagagacgaagaaagtgaccagctctggagttctcttgctggac
aactactctgaccgtatccaggtcctcaggaacatggtgcactgtgcagacctcagcaat
cccaccaagcccctggagctgtaccgacaatggactgatcgcatcatggctgagttcttc
cagcagggtgaccgagaacgggaacgcggaatggagattagccccatgtgtgacaagcac
acagcctctgtggagaagtctcaggtgggcttcatcgactatattgttcacccactgtgg
gagacgtgggccgatctcgtccaccccgatgcccaagacatcctggacacgctggaagac
aaccgggattggtatcacagtgccatccgccagagtccctccccaaccctggaagaggag
ccaggagtgctcagcgatccggccctgcctgacaagttccaatttgagctcaccttggag
gaagaggatgaagaggattcattggaggttccaggattgccttgcactgaggaaactctc
ctggctccacatgataccagagctcaagccatggaacagtcaaaggtcaaaggccagagc
cctgctgttgtggaggtagcagagagtttgaagcaggagacagcctcagcacatggcgct
cctgaggagtccgcggaggctgtgggccattccttcagccttgaaacctctattctgcct
gacttgaggaccctgtccccctcagaggaggcccagggcctcctgggcctcccctccatg
gcggcagaggtggaggccccaagagaccatctggctgccatgagggcttgttctgcctgc
tcggggacatcaggagacaattctgccgtcatctctgctccaggcaggtgggggtcaggt
ggagaccctgcctga

KEGG   Mus musculus (house mouse): 18578
Entry
18578             CDS       T01002                                 
Symbol
Pde4b, Dpde4, dunce
Name
(RefSeq) phosphodiesterase 4B, cAMP specific
  KO
K13293  cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04024  cAMP signaling pathway
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18578 (Pde4b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    18578 (Pde4b)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    18578 (Pde4b)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18578 (Pde4b)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     18578 (Pde4b)
SSDB
Motif
Pfam: PDEase_I PDE4_UCR
Other DBs
NCBI-GeneID: 18578
NCBI-ProteinID: NP_001171451
MGI: 99557
Ensembl: ENSMUSG00000028525
UniProt: Q8VBU5 B1AWD0
LinkDB
Position
4:101944529..102464459
AA seq 564 aa
MKEQGGTVSGAASSRGGGDSAMASLQPLQPNYLSVCLFPEESYQKLAMETLEELDWCLDQ
LETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPT
QKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNI
FNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAA
DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE
SVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM
VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK
ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
QSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVID
PENRDSLEETDIDIATEDKSPIDT
NT seq 1695 nt   +upstreamnt  +downstreamnt
atgaaggagcaagggggcaccgtcagtggcgccgcgagcagccgaggtggaggagactcg
gctatggccagcctgcagccactgcagcctaactacctgtctgtgtgtttgtttccagaa
gaatcatatcagaaactagcaatggagacgctggaggaactagactggtgcctagaccag
ctagagaccatccagacctaccgctctgtcagcgagatggcttcaaacaagttcaaaagg
atgctgaaccgggagctgacacacctctcagagatgagcagatcagggaaccaggtgtct
gagtacatttcaaacacgttcttagacaagcagaacgatgtggaaatcccatctcccacg
cagaaggacagggagaagaagaagaagcagcagctcatgacccagataagtggagtgaag
aaactgatgcacagctcaagcctgaacaacacaagcatctcacgcttcggagtcaacacg
gaaaatgaggatcatctagccaaggagctggaagacctgaacaaatggggccttaacatc
ttcaatgtggctgggtactcacataatcggccccttacgtgcatcatgtatgcaatattc
caggaaagagaccttctgaagacgtttaaaatctcatctgacacctttgtaacctacatg
atgactttagaagaccattaccattctgatgtggcatatcacaacagcctgcatgctgct
gacgtggcccagtcaactcacgttctcctttctacgccggcactggatgctgtcttcaca
gacctggaaatcctggctgccatttttgcagctgccatccatgatgtcgatcatcctgga
gtctccaatcagtttctcatcaatacaaattctgaacttgctttgatgtataatgatgaa
tctgttctggaaaaccatcaccttgctgtgggattcaaattgctacaagaggaacactgc
gacatctttcagaatcttaccaagaagcaacgccagacactcaggaaaatggtgattgac
atggtgttggcaactgatatgtccaaacacatgagcctcctggcagaccttaaaacaatg
gtagaaaccaagaaggtgacaagctccggtgttctcctcctggacaactatactgaccgg
atacaggttcttcgcaacatggtacactgtgcagacctgagcaaccccaccaagtccttg
gaattgtatcggcaatggaccgatcgtatcatggaggagtttttccagcagggagacaaa
gaacgggagaggggaatggagattagcccaatgtgtgataagcacacagcttctgtggaa
aaatcccaggttggtttcattgactacattgtccatccactgtgggagacctgggcagac
ctggttcaaccggatgctcaagatattctggatacactagaagataacaggaactggtac
cagagtatgataccccagagcccttccccgccactggatgagaggagcagggactgccaa
ggcctgatggagaagtttcagtttgaactgacccttgaggaagaggattctgagggaccg
gaaaaggagggagaaggccacagctatttcagcagcacaaagacgctttgtgtgattgat
ccagagaacagggattctctggaagagactgacatagacattgcaacagaagacaagtct
ccgatcgacacataa

KEGG   Mus musculus (house mouse): 18583
Entry
18583             CDS       T01002                                 
Symbol
Pde7a
Name
(RefSeq) phosphodiesterase 7A
  KO
K18436  high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18583 (Pde7a)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18583 (Pde7a)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     18583 (Pde7a)
SSDB
Motif
Pfam: PDEase_I
Other DBs
NCBI-GeneID: 18583
NCBI-ProteinID: NP_032828
MGI: 1202402
Ensembl: ENSMUSG00000069094
UniProt: P70453
LinkDB
Position
3:complement(19277272..19365486)
AA seq 456 aa
MGITLIWCLALVLIKWITSKRRGAISYDSSDQTALYIRMLGDVRVRSRAGFETERRGSHP
YIDFRIFHSQSDIEASVSARNIRRLLSFQRYLRSSRVFRGATVCSSLDILDEDYNGQAKC
MLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYH
SQNPYHNAVHAADVTQAMHCYLKEPKLASSVTPWDILLSLIAAATHDLDHPGVNQPFLIK
TNHYLATLYKNSSVLENHHWRSAVGLLRESGLFSHLPLESRQEMEAQIGALILATDISRQ
NEYLSLFRSHLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFH
QGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHVGL
NKASWKGLQRQQPSSEDANAAFELNSQLLTQENRLS
NT seq 1371 nt   +upstreamnt  +downstreamnt
atgggaatcactttgatctggtgtctggctttggttctgatcaagtggatcacctctaag
agacgtggagctatttcctatgacagttctgatcagactgcgttatatattcgtatgcta
ggagatgtccgcgtgaggagccgagcaggatttgaaacagaaagaagaggttcccatccg
tacattgacttccgtatttttcactctcaatctgacattgaagcatcagtctccgccagg
aacatcagaaggttactaagtttccagcgatatctcagatcctcacgagtttttcggggt
gccacagtttgtagttctctagacattttagatgaggattacaatggacaagccaagtgt
atgctggaaaaagttggaaattggaattttgatatctttctgtttgatagactaacaaat
ggaaatagtctagtaagcctaacctttcatttatttagtcttcatggattgattgagtac
ttccatttagatatggtgaaactccgtcggtttttagttatgattcaagaagattaccac
agtcaaaatccttaccacaatgcagtccatgctgcagacgttactcaggccatgcactgt
tacttaaaggaacctaagcttgccagttctgtcactccttgggatatcttgctgagttta
attgcagccgccactcacgatctggatcacccaggtgttaatcagccgtttcttattaaa
accaaccattatctagcaactttatacaagaattcctcagtcctggagaatcaccactgg
agatctgcagtgggcttgttaagagaatctggtttgttctcacacttgccattggaaagc
aggcaagagatggaggctcagataggtgctttgatattagccacggatatcagtcgccag
aacgagtacctgtcattgtttagatctcacttggataaaggtgacttacaccttgacgat
ggcagacataggcatttggttctacagatggccttgaaatgtgctgatatttgtaaccca
tgtcggaactgggaattaagcaagcagtggagtgaaaaagtaacggaggaattcttccac
caaggagatatagaaaaaaagtaccatttgggtgtgagtccactttgtgatcgtcagact
gagtctattgccaacatccagattggttttatgacttacctagtggagcctttatttaca
gagtgggccaggttttcagacacacggctgtcacagacgatgcttggacatgtggggctg
aataaagccagctggaagggactgcagagacaacagcccagcagcgaggatgccaatgct
gcatttgagttgaactcacagttactaactcaggaaaatcggttatcataa

KEGG   Mus musculus (house mouse): 18584
Entry
18584             CDS       T01002                                 
Symbol
Pde8a, Pde8
Name
(RefSeq) phosphodiesterase 8A
  KO
K18437  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04927  Cortisol synthesis and secretion
mmu04934  Cushing syndrome
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    18584 (Pde8a)
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    18584 (Pde8a)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    18584 (Pde8a)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    18584 (Pde8a)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     18584 (Pde8a)
SSDB
Motif
Pfam: PDEase_I PAS_9 PAS PAS_4 PAS_3 PDE8 Response_reg PAS_8
Other DBs
NCBI-GeneID: 18584
NCBI-ProteinID: NP_032829
MGI: 1277116
Ensembl: ENSMUSG00000025584
UniProt: O88502
LinkDB
Position
7:80863013..80984283
AA seq 823 aa
MGCAPSIHTSENRTFSHSDGEDEDVDVDVPGPAPRSIQRWSTAPGLVEPQPRDNGASKVS
VADVQFGPMRFHQDQLQVLLVFTKEDSQCNGFHRACEKAGFKCTVTKEVQTVLTCFQDKL
HDIIIIDHRYPRQMDAETLCRSIRSSKFSENTVIVGVVRRVDKEESSLMPFLAAGFTRRF
IENPNVMACYNELLQLACGEVRSQLKLRACNSVFTALEKSQEAIEITSEDHIIQYANPAF
ESTMGYQSGELIGKELAQVPINEKKGDLLDAINSCVTVDKEWQGVYHTQKKNGDNIQQNV
KIIPVIGQGGKIRHYVSIIRVCNGNNKVETTTECVQTDSQTDNQAGKHKDRRKHSMDAKA
VSSRTSDVSSQRRHSSLARIHSMMIEAPITKVINIINAAQENSPVPVTEALNRVLDILRT
TELYSPQFNAQDDPHATDLVGGLMSDGLRRFSGNEYILATKNLPPLSNNLATPVSLHDVP
PRIALAIENEEQWDFDIFELEVATQNRPLIYLGLKTFARFGMCEFLQCSETTLRSWFQMI
ESNYHSSNPYHNSTHAADVLHATAYFLSRDKIKETLDRIDEVAALIAATVHDVDHPGRTN
SFLCNAGNQLAVLYNDTAVLESHHVALAFQLTLENDQCNIFKQMERNDYRTLRQSIIDMV
LATEMTKHFEHVNKFINSINKPLTAQESEEPDRSLEDIKAMLKTPESRALIKRMMIKCAD
VSNPCRPLEHCIEWAARISEEYFSQTDEEKQLDLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFVDLPNLMQHLDDNFRYWKGLDEKKLRSLRPPPE
NT seq 2472 nt   +upstreamnt  +downstreamnt
atgggctgcgccccgagcatccacacttccgaaaaccgaacgtttagccacagcgacggc
gaggacgaggacgtggacgtggacgtcccgggccccgcgccgagatctattcagcgatgg
tcgaccgcgcccgggctcgtggagcctcagcctcgggataacggcgcctcgaaggtatca
gtagctgatgtgcaatttggcccgatgagatttcatcaagaccaacttcaggtcctgtta
gtgtttaccaaagaagatagccagtgtaacggattccacagggcatgtgagaaagctggg
tttaagtgcacagtcaccaaggaggtgcagactgtccttacctgtttccaggacaaactc
catgacatcatcatcatagaccacagatatccccgacagatggatgcagagacattgtgc
aggtctatcagatcatcaaaattctcagaaaacacagttattgttggcgtagtacgcagg
gtggacaaagaagaatcatctttaatgcccttccttgctgctggcttcacacggaggttt
atagagaaccccaacgtcatggcctgttataatgaactgctccagttggcatgtggagag
gtgcgatcacagctgaaactcagggcttgtaactcagtattcactgcattagagaaaagt
caagaagcaattgaaattacaagtgaagaccacattatacagtatgcaaaccctgcattt
gaatcaacaatgggttatcagtcaggagaattaatagggaaggagttagcacaagtgccc
ataaatgaaaagaaaggtgatttgctcgatgccataaattcgtgtgtcacagtagacaag
gaatggcaaggagtttaccatacccaaaagaaaaatggagataacatacagcaaaatgtg
aagataatacctgtcattgggcagggaggaaaaatcagacactatgtgtccattatcaga
gtgtgcaatggcaacaataaggttgagaccacaactgagtgtgttcagactgacagtcaa
acagataaccaggcaggcaaacataaggacaggaggaaacattcgatggacgccaaagcg
gtttcctccagaacaagtgacgtttccagtcagagaagacattcctctttggcccggata
cattctatgatgattgaggcacccatcaccaaggtaatcaatattatcaatgctgcccag
gaaaacagtcctgtgcctgtgacggaagccttgaaccgagtgctggatattctgagaacc
actgagctgtactcgccacagtttaatgctcaggatgatccccatgccacagacctcgtt
gggggcttaatgtctgatggcttacgaaggttttcaggaaatgagtatattcttgcaaca
aaaaacctcccaccactttcaaacaatttggccacccccgtctcccttcatgatgtccca
ccacggattgccctggccatagaaaatgaagaacagtgggactttgacatttttgagctg
gaagtagcaacccaaaataggcctttgatttatctaggtctgaaaacgtttgcgcgtttt
ggaatgtgtgagttcttacagtgctctgagacaacgctgagatcttggtttcagatgatc
gaatccaactaccactcttctaacccctaccacaattccacacacgctgcggatgtgctt
cacgccacggcgtatttcctttccagagacaaaataaaggaaactttagatcgcattgac
gaggttgctgccctcattgcggccaccgtccatgacgtggatcaccctgggagaaccaac
tccttcctgtgcaacgcgggaaaccagctggctgtgctctacaacgacaccgctgtgctg
gagagccaccacgtggcactggccttccagctgacgcttgaaaatgaccagtgcaatatc
tttaagcaaatggagaggaatgactaccggacactacgccagagcattattgacatggtc
ctagccacagaaatgacgaagcactttgaacatgtcaacaaatttatcaacagcatcaac
aagcctttgacagcccaggagagtgaggaacctgacagaagtctggaagacataaaagct
atgctcaagacgccagagagccgggctctcatcaaaagaatgatgattaagtgtgccgac
gtgtccaacccctgccggccgctggagcactgcatcgagtgggctgcgcgcatctcagag
gagtatttctctcagactgatgaagagaaacagctggacttgcctgtggtgatgcccgtg
tttgacagaaacacctgcagcattcccaagtctcagatctccttcatcgattacttcatc
acagacatgtttgatgcctgggatgccttcgttgacctgcctaaccttatgcagcaccta
gatgacaacttcaggtactggaaaggactggatgagaagaagcttcgaagcctccgcccc
cctccagagtag

KEGG   Mus musculus (house mouse): 207728
Entry
207728            CDS       T01002                                 
Symbol
Pde2a, CGS-PDE, cGSPDE
Name
(RefSeq) phosphodiesterase 2A, cGMP-stimulated
  KO
K18283  cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu01100  Metabolic pathways
mmu04022  cGMP-PKG signaling pathway
mmu04740  Olfactory transduction
mmu04925  Aldosterone synthesis and secretion
mmu05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    207728 (Pde2a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    207728 (Pde2a)
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    207728 (Pde2a)
  09157 Sensory system
   04740 Olfactory transduction
    207728 (Pde2a)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    207728 (Pde2a)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     207728 (Pde2a)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3
Other DBs
NCBI-GeneID: 207728
NCBI-ProteinID: NP_001137320
MGI: 2446107
Ensembl: ENSMUSG00000030653 ENSMUSG00000110195
UniProt: Q922S4
Structure
LinkDB
Position
7:101070905..101162026
AA seq 939 aa
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPQPCADSLQDALLSLGAVIDIAG
LRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIREAVISQKRLSCNGL
GPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEK
HALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQ
LKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQC
IQLKDLTSDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDE
DEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEA
RNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDA
YAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFS
IYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFA
NFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHA
FSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSS
EGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQ
KMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMG
NRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHK
FTIRGLPSNNSLDFLDEEYEVPDLDGTRAPVNGCCSLEG
NT seq 2820 nt   +upstreamnt  +downstreamnt
atggggcaggcatgcggccactccatcctctgcaggagccagcagtacccggcagcgcga
ccggctgagccgcggggccagcaggtcttcctcaagccggacgagccgccgccgcagcca
tgcgccgacagcctgcaggatgctttgctgagcctaggcgccgttatcgacattgctggc
ctgcgacaggctgccagggatgccctctcagccgtgctccccaaagtggagactgtctac
acctacctgctagatggggagtccagactggtgtgtgaggacccccctcatgagctgcca
caggaaggaaaaattcgagaagctgtgatctctcagaagcggctgagttgcaatgggctg
ggaccttcggacctactgggaaagcccttggccaggctggtggctccactggctcctgac
atgcaagtgctggtcatacccctgctggacaaggagactggaagtgtggcagctgtcatc
ttggtgcactgtggccagctgagtgacagtgaggaacagagcttgcaggtggtagagaag
cacgctctggtagccctgcggagggtgcaggccctgcagcagcgcaggcctgaagctgtt
cagaacacgtcagtggatgcctctgaagatcaaaaggatgagaaggggtacaccgaccat
gaccgaaagatcctgcaactgtgtggggaactctttgacttggatgctacttctctgcag
ctcaaagtccttcaatatctgcagcaggagacacaggccactcactgctgcctcctgctg
gtgtcggaggacaatctacagctttcctgcaaggtcattggagacaaagtgctgggagaa
gaggtcagctttccattgaccatgggacgtctggggcaggtggtggaagacaagcagtgt
atccagttgaaggacctaacctctgacgatgtgcaacagctgcaaaacatgttgggttgt
gagctgcaggctatgctgtgtgtccctgtcatcagccgagccactgaccaggtggtggcc
ctggcttgcgccttcaacaagcttggaggagatttcccgacttccagcttcacagatgag
gatgaacacgtgatccaacactgcttccactacacaggcacggtgctcaccagcaccttg
gccttccagaaggagcagaagctcaagtgtgagtgccaggctcttctccaagtggcaaag
aacctcttcacccacctggatgatgtctctgtcctgctacaggagatcatcacggaagcc
agaaacctcagcaacgcagagatctgctcggtgttcctgctggatcagaacgagctggtg
gccaaggtgttcgatggtggcgttgtggacgatgagagttatgagatccgcatcccggcg
gaccaaggcatcgcgggccacgtggcgactacgggccagatcctgaacatcccagatgca
tatgcccatccgcttttctatcgcggcgtagatgacagcactggcttccgcacgcgcaac
attctctgcttccctatcaagaacgagaaccaggaggtcattggtgtggctgagctagtg
aacaagatcaatgggccatggttcagcaagtttgatgaggacctggccacagccttctcc
atctactgtggcatcagcatcgcccactctctcctatacaaaaaggtgaatgaagcccaa
taccgcagccacctggccaatgagatgatgatgtatcatatgaaggtctctgatgatgaa
tacaccaagcttctccacgatggcatccaacctgtggccgccattgactccaactttgcc
aactttacctacacgcctcggtctctgcctgaggacgacacttctatggccatcctgagc
atgctgcaagacatgaacttcatcaataactacaaaattgactgcccaactctggcccga
ttctgcctgatggtgaagaaaggctaccgggatccaccctaccacaactggatgcacgcc
ttctctgtctctcatttttgctacctgctctacaagaatctggagctctccaactacctc
gaggacatcgagatctttgcattgtttatttcctgcatgtgtcatgacctggaccacaga
ggcacaaacaactccttccaggtggcctcgaaatctgtgctggccgcactctacagctca
gagggctctgtcatggagaggcaccactttgctcaagccattgctatcctcaacacccac
ggctgcaatatctttgaccacttctctcggaaggactatcagcgcatgctggacctgatg
agggacatcatcttggctacagacctggcacaccacctccgcatcttcaaggacctgcag
aagatggctgaagtgggttatgaccgaaacaacaggcaacaccacaggcttcttctgtgc
ctcctcatgacctcctgtgacctctctgaccagacaaagggctggaagaccaccagaaag
attgcagagctgatctacaaagagttcttctcccagggagacttggagaaggccatgggc
aaccgaccgatggagatgatggaccgtgagaaggcctacatccctgagcttcagatcagc
tttatggagcacattgccatgcctatctacaagcttttacaagacctgttccccaaggcg
gcagagctgtatgaacgtgtggcctccaaccgtgagcactggaccaaggtgtcccacaag
ttcaccatccgaggcctccccagtaacaactcgctggatttcctggacgaggaatacgag
gtccccgatttggacggcaccagagctcctgtcaatggctgctgcagcctcgagggctga

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