Mus musculus (house mouse): 11651 Help Entry 11651             CDS       T01002                                  Symbol Akt1, Akt, LTR-akt, PKB, PKB/Akt, PKBalpha, Rac Name (RefSeq) thymoma viral proto-oncogene 1   KO K04456   RAC serine/threonine-protein kinase [EC:2.7.11.1] Organism mmu  Mus musculus (house mouse) Pathway mmu01521   EGFR tyrosine kinase inhibitor resistance mmu01522   Endocrine resistance mmu01524   Platinum drug resistance mmu04010   MAPK signaling pathway mmu04012   ErbB signaling pathway mmu04014   Ras signaling pathway mmu04015   Rap1 signaling pathway mmu04022   cGMP-PKG signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04066   HIF-1 signaling pathway mmu04068   FoxO signaling pathway mmu04071   Sphingolipid signaling pathway mmu04072   Phospholipase D signaling pathway mmu04140   Autophagy - animal mmu04150   mTOR signaling pathway mmu04151   PI3K-Akt signaling pathway mmu04152   AMPK signaling pathway mmu04210   Apoptosis mmu04211   Longevity regulating pathway mmu04213   Longevity regulating pathway - multiple species mmu04218   Cellular senescence mmu04261   Adrenergic signaling in cardiomyocytes mmu04370   VEGF signaling pathway mmu04371   Apelin signaling pathway mmu04380   Osteoclast differentiation mmu04510   Focal adhesion mmu04550   Signaling pathways regulating pluripotency of stem cells mmu04611   Platelet activation mmu04613   Neutrophil extracellular trap formation mmu04620   Toll-like receptor signaling pathway mmu04625   C-type lectin receptor signaling pathway mmu04630   JAK-STAT signaling pathway mmu04660   T cell receptor signaling pathway mmu04662   B cell receptor signaling pathway mmu04664   Fc epsilon RI signaling pathway mmu04666   Fc gamma R-mediated phagocytosis mmu04668   TNF signaling pathway mmu04722   Neurotrophin signaling pathway mmu04725   Cholinergic synapse mmu04728   Dopaminergic synapse mmu04810   Regulation of actin cytoskeleton mmu04910   Insulin signaling pathway mmu04914   Progesterone-mediated oocyte maturation mmu04915   Estrogen signaling pathway mmu04917   Prolactin signaling pathway mmu04919   Thyroid hormone signaling pathway mmu04920   Adipocytokine signaling pathway mmu04922   Glucagon signaling pathway mmu04923   Regulation of lipolysis in adipocytes mmu04926   Relaxin signaling pathway mmu04929   GnRH secretion mmu04931   Insulin resistance mmu04932   Non-alcoholic fatty liver disease mmu04933   AGE-RAGE signaling pathway in diabetic complications mmu04935   Growth hormone synthesis, secretion and action mmu04936   Alcoholic liver disease mmu04973   Carbohydrate digestion and absorption mmu05010   Alzheimer disease mmu05017   Spinocerebellar ataxia mmu05132   Salmonella infection mmu05135   Yersinia infection mmu05142   Chagas disease mmu05145   Toxoplasmosis mmu05152   Tuberculosis mmu05160   Hepatitis C mmu05161   Hepatitis B mmu05162   Measles mmu05163   Human cytomegalovirus infection mmu05164   Influenza A mmu05165   Human papillomavirus infection mmu05166   Human T-cell leukemia virus 1 infection mmu05167   Kaposi sarcoma-associated herpesvirus infection mmu05168   Herpes simplex virus 1 infection mmu05169   Epstein-Barr virus infection mmu05170   Human immunodeficiency virus 1 infection mmu05200   Pathways in cancer mmu05205   Proteoglycans in cancer mmu05207   Chemical carcinogenesis - receptor activation mmu05208   Chemical carcinogenesis - reactive oxygen species mmu05210   Colorectal cancer mmu05211   Renal cell carcinoma mmu05212   Pancreatic cancer mmu05213   Endometrial cancer mmu05214   Glioma mmu05215   Prostate cancer mmu05218   Melanoma mmu05220   Chronic myeloid leukemia mmu05221   Acute myeloid leukemia mmu05222   Small cell lung cancer mmu05223   Non-small cell lung cancer mmu05224   Breast cancer mmu05225   Hepatocellular carcinoma mmu05226   Gastric cancer mmu05230   Central carbon metabolism in cancer mmu05231   Choline metabolism in cancer mmu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mmu05415   Diabetic cardiomyopathy mmu05417   Lipid and atherosclerosis mmu05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     11651 (Akt1)    04012 ErbB signaling pathway     11651 (Akt1)    04014 Ras signaling pathway     11651 (Akt1)    04015 Rap1 signaling pathway     11651 (Akt1)    04370 VEGF signaling pathway     11651 (Akt1)    04371 Apelin signaling pathway     11651 (Akt1)    04630 JAK-STAT signaling pathway     11651 (Akt1)    04668 TNF signaling pathway     11651 (Akt1)    04066 HIF-1 signaling pathway     11651 (Akt1)    04068 FoxO signaling pathway     11651 (Akt1)    04072 Phospholipase D signaling pathway     11651 (Akt1)    04071 Sphingolipid signaling pathway     11651 (Akt1)    04024 cAMP signaling pathway     11651 (Akt1)    04022 cGMP-PKG signaling pathway     11651 (Akt1)    04151 PI3K-Akt signaling pathway     11651 (Akt1)    04152 AMPK signaling pathway     11651 (Akt1)    04150 mTOR signaling pathway     11651 (Akt1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     11651 (Akt1)   09143 Cell growth and death    04210 Apoptosis     11651 (Akt1)    04218 Cellular senescence     11651 (Akt1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     11651 (Akt1)    04550 Signaling pathways regulating pluripotency of stem cells     11651 (Akt1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     11651 (Akt1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     11651 (Akt1)    04613 Neutrophil extracellular trap formation     11651 (Akt1)    04620 Toll-like receptor signaling pathway     11651 (Akt1)    04625 C-type lectin receptor signaling pathway     11651 (Akt1)    04660 T cell receptor signaling pathway     11651 (Akt1)    04662 B cell receptor signaling pathway     11651 (Akt1)    04664 Fc epsilon RI signaling pathway     11651 (Akt1)    04666 Fc gamma R-mediated phagocytosis     11651 (Akt1)    04062 Chemokine signaling pathway     11651 (Akt1)   09152 Endocrine system    04910 Insulin signaling pathway     11651 (Akt1)    04922 Glucagon signaling pathway     11651 (Akt1)    04923 Regulation of lipolysis in adipocytes     11651 (Akt1)    04920 Adipocytokine signaling pathway     11651 (Akt1)    04929 GnRH secretion     11651 (Akt1)    04915 Estrogen signaling pathway     11651 (Akt1)    04914 Progesterone-mediated oocyte maturation     11651 (Akt1)    04917 Prolactin signaling pathway     11651 (Akt1)    04926 Relaxin signaling pathway     11651 (Akt1)    04935 Growth hormone synthesis, secretion and action     11651 (Akt1)    04919 Thyroid hormone signaling pathway     11651 (Akt1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     11651 (Akt1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     11651 (Akt1)   09156 Nervous system    04725 Cholinergic synapse     11651 (Akt1)    04728 Dopaminergic synapse     11651 (Akt1)    04722 Neurotrophin signaling pathway     11651 (Akt1)   09158 Development and regeneration    04380 Osteoclast differentiation     11651 (Akt1)   09149 Aging    04211 Longevity regulating pathway     11651 (Akt1)    04213 Longevity regulating pathway - multiple species     11651 (Akt1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     11651 (Akt1)    05205 Proteoglycans in cancer     11651 (Akt1)    05207 Chemical carcinogenesis - receptor activation     11651 (Akt1)    05208 Chemical carcinogenesis - reactive oxygen species     11651 (Akt1)    05230 Central carbon metabolism in cancer     11651 (Akt1)    05231 Choline metabolism in cancer     11651 (Akt1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     11651 (Akt1)   09162 Cancer: specific types    05210 Colorectal cancer     11651 (Akt1)    05212 Pancreatic cancer     11651 (Akt1)    05225 Hepatocellular carcinoma     11651 (Akt1)    05226 Gastric cancer     11651 (Akt1)    05214 Glioma     11651 (Akt1)    05221 Acute myeloid leukemia     11651 (Akt1)    05220 Chronic myeloid leukemia     11651 (Akt1)    05218 Melanoma     11651 (Akt1)    05211 Renal cell carcinoma     11651 (Akt1)    05215 Prostate cancer     11651 (Akt1)    05213 Endometrial cancer     11651 (Akt1)    05224 Breast cancer     11651 (Akt1)    05222 Small cell lung cancer     11651 (Akt1)    05223 Non-small cell lung cancer     11651 (Akt1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     11651 (Akt1)    05170 Human immunodeficiency virus 1 infection     11651 (Akt1)    05161 Hepatitis B     11651 (Akt1)    05160 Hepatitis C     11651 (Akt1)    05164 Influenza A     11651 (Akt1)    05162 Measles     11651 (Akt1)    05168 Herpes simplex virus 1 infection     11651 (Akt1)    05163 Human cytomegalovirus infection     11651 (Akt1)    05167 Kaposi sarcoma-associated herpesvirus infection     11651 (Akt1)    05169 Epstein-Barr virus infection     11651 (Akt1)    05165 Human papillomavirus infection     11651 (Akt1)   09171 Infectious disease: bacterial    05132 Salmonella infection     11651 (Akt1)    05135 Yersinia infection     11651 (Akt1)    05152 Tuberculosis     11651 (Akt1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     11651 (Akt1)    05142 Chagas disease     11651 (Akt1)   09164 Neurodegenerative disease    05010 Alzheimer disease     11651 (Akt1)    05017 Spinocerebellar ataxia     11651 (Akt1)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     11651 (Akt1)    05418 Fluid shear stress and atherosclerosis     11651 (Akt1)    05415 Diabetic cardiomyopathy     11651 (Akt1)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     11651 (Akt1)    04932 Non-alcoholic fatty liver disease     11651 (Akt1)    04931 Insulin resistance     11651 (Akt1)    04933 AGE-RAGE signaling pathway in diabetic complications     11651 (Akt1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     11651 (Akt1)    01524 Platinum drug resistance     11651 (Akt1)    01522 Endocrine resistance     11651 (Akt1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmu01001]     11651 (Akt1) Enzymes [BR:mmu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      11651 (Akt1) Protein kinases [BR:mmu01001]  Serine/threonine kinases: AGC group   AKT/PKB family    11651 (Akt1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_11 PH_20 Amphi-Trp Seadorna_VP7 Motif Other DBs NCBI-GeneID:  11651 NCBI-ProteinID:  NP_001318036 MGI:  87986 Ensembl:  ENSMUSG00000001729 UniProt:  P31750 LinkDB All DBs Position 12:complement(112620260..112641266) Genome browser AA seq 480 aa AA seqDB search MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSVAQC QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWATAIQTVADGLKRQEEETMDF RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL ILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKK LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA NT seq 1443 nt NT seq  +upstreamnt  +downstreamnt atgaacgacgtagccattgtgaaggagggctggctgcacaaacgaggggaatatattaaa acctggcggccacgctacttcctcctcaagaacgatggcacctttattggctacaaggaa cggcctcaggatgtggatcagcgagagtccccactcaacaacttctcagtggcacaatgc cagctgatgaagacagagcggccaaggcccaacacctttatcatccgctgcctgcagtgg accacagtcattgagcgcaccttccatgtggaaacgcctgaggagcgggaagaatgggcc accgccattcagactgtggcagatggactcaagaggcaggaagaagagacgatggacttc cgatcaggctcacccagtgacaactcaggggctgaagagatggaggtgtccctggccaag cccaagcaccgtgtgaccatgaacgagtttgagtacctgaagctactgggcaagggcacc tttgggaaggtgattctggtgaaagagaaggccacaggccgctactatgccatgaagatc ctcaagaaggaggtcatcgtcgccaaggatgaggttgcccacacgcttactgagaaccgt gtcctgcagaactctaggcatcccttccttacggccctcaagtactcattccagacccac gaccgcctctgctttgtcatggagtatgccaacgggggcgagctcttcttccacctgtct cgagagcgtgtgttctccgaggaccgggcccgcttctatggtgcggagattgtgtctgcc ctggactacttgcactccgagaagaacgtggtgtaccgggacctgaagctggagaacctc atgctggacaaggacgggcacatcaagataacggacttcgggctgtgcaaggaggggatc aaggacggtgccactatgaagacattctgcggaacgccggagtacctggcccctgaggtg ctggaggacaacgactacggccgtgcagtggactggtgggggctgggcgtggtcatgtac gagatgatgtgtggccgcctgcccttctacaaccaggaccacgagaagctgttcgagctg atcctcatggaggagatccgcttcccgcgcacactcggccctgaggccaagtccctgctc tccgggctgctcaagaaggaccctacacagaggctcggtgggggctccgaggatgccaag gagatcatgcagcaccggttctttgccaacatcgtgtggcaggatgtgtatgagaagaag ctgagcccacctttcaagccccaggtcacctctgagactgacaccaggtatttcgatgag gagttcacagctcagatgatcaccatcacgccgcctgatcaagatgacagcatggagtgt gtggacagtgagcggaggccgcacttcccccagttctcctactcagccagtggcacagcc tga

Mus musculus (house mouse): 11652 Help Entry 11652             CDS       T01002                                  Symbol Akt2, 2410016A19Rik, PKB, PKBbeta Name (RefSeq) thymoma viral proto-oncogene 2   KO K04456   RAC serine/threonine-protein kinase [EC:2.7.11.1] Organism mmu  Mus musculus (house mouse) Pathway mmu01521   EGFR tyrosine kinase inhibitor resistance mmu01522   Endocrine resistance mmu01524   Platinum drug resistance mmu04010   MAPK signaling pathway mmu04012   ErbB signaling pathway mmu04014   Ras signaling pathway mmu04015   Rap1 signaling pathway mmu04022   cGMP-PKG signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04066   HIF-1 signaling pathway mmu04068   FoxO signaling pathway mmu04071   Sphingolipid signaling pathway mmu04072   Phospholipase D signaling pathway mmu04140   Autophagy - animal mmu04150   mTOR signaling pathway mmu04151   PI3K-Akt signaling pathway mmu04152   AMPK signaling pathway mmu04210   Apoptosis mmu04211   Longevity regulating pathway mmu04213   Longevity regulating pathway - multiple species mmu04218   Cellular senescence mmu04261   Adrenergic signaling in cardiomyocytes mmu04370   VEGF signaling pathway mmu04371   Apelin signaling pathway mmu04380   Osteoclast differentiation mmu04510   Focal adhesion mmu04550   Signaling pathways regulating pluripotency of stem cells mmu04611   Platelet activation mmu04613   Neutrophil extracellular trap formation mmu04620   Toll-like receptor signaling pathway mmu04625   C-type lectin receptor signaling pathway mmu04630   JAK-STAT signaling pathway mmu04660   T cell receptor signaling pathway mmu04662   B cell receptor signaling pathway mmu04664   Fc epsilon RI signaling pathway mmu04666   Fc gamma R-mediated phagocytosis mmu04668   TNF signaling pathway mmu04722   Neurotrophin signaling pathway mmu04725   Cholinergic synapse mmu04728   Dopaminergic synapse mmu04810   Regulation of actin cytoskeleton mmu04910   Insulin signaling pathway mmu04914   Progesterone-mediated oocyte maturation mmu04915   Estrogen signaling pathway mmu04917   Prolactin signaling pathway mmu04919   Thyroid hormone signaling pathway mmu04920   Adipocytokine signaling pathway mmu04922   Glucagon signaling pathway mmu04923   Regulation of lipolysis in adipocytes mmu04926   Relaxin signaling pathway mmu04929   GnRH secretion mmu04931   Insulin resistance mmu04932   Non-alcoholic fatty liver disease mmu04933   AGE-RAGE signaling pathway in diabetic complications mmu04935   Growth hormone synthesis, secretion and action mmu04936   Alcoholic liver disease mmu04973   Carbohydrate digestion and absorption mmu05010   Alzheimer disease mmu05017   Spinocerebellar ataxia mmu05132   Salmonella infection mmu05135   Yersinia infection mmu05142   Chagas disease mmu05145   Toxoplasmosis mmu05152   Tuberculosis mmu05160   Hepatitis C mmu05161   Hepatitis B mmu05162   Measles mmu05163   Human cytomegalovirus infection mmu05164   Influenza A mmu05165   Human papillomavirus infection mmu05166   Human T-cell leukemia virus 1 infection mmu05167   Kaposi sarcoma-associated herpesvirus infection mmu05168   Herpes simplex virus 1 infection mmu05169   Epstein-Barr virus infection mmu05170   Human immunodeficiency virus 1 infection mmu05200   Pathways in cancer mmu05205   Proteoglycans in cancer mmu05207   Chemical carcinogenesis - receptor activation mmu05208   Chemical carcinogenesis - reactive oxygen species mmu05210   Colorectal cancer mmu05211   Renal cell carcinoma mmu05212   Pancreatic cancer mmu05213   Endometrial cancer mmu05214   Glioma mmu05215   Prostate cancer mmu05218   Melanoma mmu05220   Chronic myeloid leukemia mmu05221   Acute myeloid leukemia mmu05222   Small cell lung cancer mmu05223   Non-small cell lung cancer mmu05224   Breast cancer mmu05225   Hepatocellular carcinoma mmu05226   Gastric cancer mmu05230   Central carbon metabolism in cancer mmu05231   Choline metabolism in cancer mmu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mmu05415   Diabetic cardiomyopathy mmu05417   Lipid and atherosclerosis mmu05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     11652 (Akt2)    04012 ErbB signaling pathway     11652 (Akt2)    04014 Ras signaling pathway     11652 (Akt2)    04015 Rap1 signaling pathway     11652 (Akt2)    04370 VEGF signaling pathway     11652 (Akt2)    04371 Apelin signaling pathway     11652 (Akt2)    04630 JAK-STAT signaling pathway     11652 (Akt2)    04668 TNF signaling pathway     11652 (Akt2)    04066 HIF-1 signaling pathway     11652 (Akt2)    04068 FoxO signaling pathway     11652 (Akt2)    04072 Phospholipase D signaling pathway     11652 (Akt2)    04071 Sphingolipid signaling pathway     11652 (Akt2)    04024 cAMP signaling pathway     11652 (Akt2)    04022 cGMP-PKG signaling pathway     11652 (Akt2)    04151 PI3K-Akt signaling pathway     11652 (Akt2)    04152 AMPK signaling pathway     11652 (Akt2)    04150 mTOR signaling pathway     11652 (Akt2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     11652 (Akt2)   09143 Cell growth and death    04210 Apoptosis     11652 (Akt2)    04218 Cellular senescence     11652 (Akt2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     11652 (Akt2)    04550 Signaling pathways regulating pluripotency of stem cells     11652 (Akt2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     11652 (Akt2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     11652 (Akt2)    04613 Neutrophil extracellular trap formation     11652 (Akt2)    04620 Toll-like receptor signaling pathway     11652 (Akt2)    04625 C-type lectin receptor signaling pathway     11652 (Akt2)    04660 T cell receptor signaling pathway     11652 (Akt2)    04662 B cell receptor signaling pathway     11652 (Akt2)    04664 Fc epsilon RI signaling pathway     11652 (Akt2)    04666 Fc gamma R-mediated phagocytosis     11652 (Akt2)    04062 Chemokine signaling pathway     11652 (Akt2)   09152 Endocrine system    04910 Insulin signaling pathway     11652 (Akt2)    04922 Glucagon signaling pathway     11652 (Akt2)    04923 Regulation of lipolysis in adipocytes     11652 (Akt2)    04920 Adipocytokine signaling pathway     11652 (Akt2)    04929 GnRH secretion     11652 (Akt2)    04915 Estrogen signaling pathway     11652 (Akt2)    04914 Progesterone-mediated oocyte maturation     11652 (Akt2)    04917 Prolactin signaling pathway     11652 (Akt2)    04926 Relaxin signaling pathway     11652 (Akt2)    04935 Growth hormone synthesis, secretion and action     11652 (Akt2)    04919 Thyroid hormone signaling pathway     11652 (Akt2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     11652 (Akt2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     11652 (Akt2)   09156 Nervous system    04725 Cholinergic synapse     11652 (Akt2)    04728 Dopaminergic synapse     11652 (Akt2)    04722 Neurotrophin signaling pathway     11652 (Akt2)   09158 Development and regeneration    04380 Osteoclast differentiation     11652 (Akt2)   09149 Aging    04211 Longevity regulating pathway     11652 (Akt2)    04213 Longevity regulating pathway - multiple species     11652 (Akt2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     11652 (Akt2)    05205 Proteoglycans in cancer     11652 (Akt2)    05207 Chemical carcinogenesis - receptor activation     11652 (Akt2)    05208 Chemical carcinogenesis - reactive oxygen species     11652 (Akt2)    05230 Central carbon metabolism in cancer     11652 (Akt2)    05231 Choline metabolism in cancer     11652 (Akt2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     11652 (Akt2)   09162 Cancer: specific types    05210 Colorectal cancer     11652 (Akt2)    05212 Pancreatic cancer     11652 (Akt2)    05225 Hepatocellular carcinoma     11652 (Akt2)    05226 Gastric cancer     11652 (Akt2)    05214 Glioma     11652 (Akt2)    05221 Acute myeloid leukemia     11652 (Akt2)    05220 Chronic myeloid leukemia     11652 (Akt2)    05218 Melanoma     11652 (Akt2)    05211 Renal cell carcinoma     11652 (Akt2)    05215 Prostate cancer     11652 (Akt2)    05213 Endometrial cancer     11652 (Akt2)    05224 Breast cancer     11652 (Akt2)    05222 Small cell lung cancer     11652 (Akt2)    05223 Non-small cell lung cancer     11652 (Akt2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     11652 (Akt2)    05170 Human immunodeficiency virus 1 infection     11652 (Akt2)    05161 Hepatitis B     11652 (Akt2)    05160 Hepatitis C     11652 (Akt2)    05164 Influenza A     11652 (Akt2)    05162 Measles     11652 (Akt2)    05168 Herpes simplex virus 1 infection     11652 (Akt2)    05163 Human cytomegalovirus infection     11652 (Akt2)    05167 Kaposi sarcoma-associated herpesvirus infection     11652 (Akt2)    05169 Epstein-Barr virus infection     11652 (Akt2)    05165 Human papillomavirus infection     11652 (Akt2)   09171 Infectious disease: bacterial    05132 Salmonella infection     11652 (Akt2)    05135 Yersinia infection     11652 (Akt2)    05152 Tuberculosis     11652 (Akt2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     11652 (Akt2)    05142 Chagas disease     11652 (Akt2)   09164 Neurodegenerative disease    05010 Alzheimer disease     11652 (Akt2)    05017 Spinocerebellar ataxia     11652 (Akt2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     11652 (Akt2)    05418 Fluid shear stress and atherosclerosis     11652 (Akt2)    05415 Diabetic cardiomyopathy     11652 (Akt2)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     11652 (Akt2)    04932 Non-alcoholic fatty liver disease     11652 (Akt2)    04931 Insulin resistance     11652 (Akt2)    04933 AGE-RAGE signaling pathway in diabetic complications     11652 (Akt2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     11652 (Akt2)    01524 Platinum drug resistance     11652 (Akt2)    01522 Endocrine resistance     11652 (Akt2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmu01001]     11652 (Akt2) Enzymes [BR:mmu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      11652 (Akt2) Protein kinases [BR:mmu01001]  Serine/threonine kinases: AGC group   AKT/PKB family    11652 (Akt2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 PH_11 ABC1 Motif Other DBs NCBI-GeneID:  11652 NCBI-ProteinID:  NP_001103678 MGI:  104874 Ensembl:  ENSMUSG00000004056 UniProt:  Q60823 Q3TY95 Q8CE74 LinkDB All DBs Position 7:27290977..27340251 Genome browser AA seq 481 aa AA seqDB search MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGEDAM DYKCGSPSDSSTSEMMEVAVNKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE LILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLDPLELDQRTHFPQFSYSASIR E NT seq 1446 nt NT seq  +upstreamnt  +downstreamnt atgaatgaggtatctgtcatcaaagaaggctggctccacaaacgtggtgaatacatcaag acctggaggccacggtacttccttctgaagagtgatggatctttcattgggtataaggag aggcccgaggcccctgaccagaccttaccccccctgaacaatttctctgtagcagaatgc cagctgatgaagactgagaggccacgacccaacacctttgtcatacgctgcctgcagtgg accacagtcatcgagaggaccttccatgtagactctccagatgagagggaagagtggatg cgggctatccagatggtcgccaacagtctgaagcagcggggcccaggtgaggacgccatg gattacaagtgtggctcccccagtgactcttccacatctgagatgatggaggtagctgtc aacaaggcacgggccaaagtgaccatgaatgacttcgattatctcaaactcctcggcaag ggcaccttcggcaaggtcattctggttcgagagaaggccactggccgctattatgccatg aagatcctgcgcaaggaggtcatcattgcaaaggatgaagtcgcccacacagtcacagag agccgggttctgcagaataccaggcaccccttccttacagccctcaagtatgccttccag acccatgaccgcctatgctttgtgatggagtatgccaacgggggtgagctgtttttccac ctctctcgggagcgagtcttcacggaggatcgggcgcgcttttatggagcagagattgtg tcagctctggagtatttgcactcgagagatgtggtgtaccgtgacatcaagctggaaaac cttatgttggacaaagatggccacatcaagatcactgactttggcttgtgcaaagagggc atcagtgatggagccaccatgaaaaccttctgtggtaccccggagtacttggcgcctgag gtgctagaggacaatgactatgggcgagcagtggactggtgggggctgggtgtggtcatg tatgagatgatgtgtggccgcctgccattctacaaccaggaccacgagcgcctctttgag ctcattcttatggaggagatccgcttcccgcgcacactcgggccagaggccaagtccctg ctggctggactgctgaagaaggacccaaagcagaggctcggcggaggtcccagtgatgcg aaggaggtcatggagcatagattcttcctcagcatcaactggcaggacgtggtacagaaa aagctcctgccacccttcaaacctcaggtcacttcagaagtggacacaaggtactttgat gacgagttcaccgcccagtccatcacaatcacacccccagaccgatatgacagcctggac ccgctggaactggaccagcggacgcacttcccccagttctcctactcagccagcatccga gagtga

Mus musculus (house mouse): 23797 Help Entry 23797             CDS       T01002                                  Symbol Akt3, D930002M15Rik, Nmf350 Name (RefSeq) thymoma viral proto-oncogene 3   KO K04456   RAC serine/threonine-protein kinase [EC:2.7.11.1] Organism mmu  Mus musculus (house mouse) Pathway mmu01521   EGFR tyrosine kinase inhibitor resistance mmu01522   Endocrine resistance mmu01524   Platinum drug resistance mmu04010   MAPK signaling pathway mmu04012   ErbB signaling pathway mmu04014   Ras signaling pathway mmu04015   Rap1 signaling pathway mmu04022   cGMP-PKG signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04066   HIF-1 signaling pathway mmu04068   FoxO signaling pathway mmu04071   Sphingolipid signaling pathway mmu04072   Phospholipase D signaling pathway mmu04140   Autophagy - animal mmu04150   mTOR signaling pathway mmu04151   PI3K-Akt signaling pathway mmu04152   AMPK signaling pathway mmu04210   Apoptosis mmu04211   Longevity regulating pathway mmu04213   Longevity regulating pathway - multiple species mmu04218   Cellular senescence mmu04261   Adrenergic signaling in cardiomyocytes mmu04370   VEGF signaling pathway mmu04371   Apelin signaling pathway mmu04380   Osteoclast differentiation mmu04510   Focal adhesion mmu04550   Signaling pathways regulating pluripotency of stem cells mmu04611   Platelet activation mmu04613   Neutrophil extracellular trap formation mmu04620   Toll-like receptor signaling pathway mmu04625   C-type lectin receptor signaling pathway mmu04630   JAK-STAT signaling pathway mmu04660   T cell receptor signaling pathway mmu04662   B cell receptor signaling pathway mmu04664   Fc epsilon RI signaling pathway mmu04666   Fc gamma R-mediated phagocytosis mmu04668   TNF signaling pathway mmu04722   Neurotrophin signaling pathway mmu04725   Cholinergic synapse mmu04728   Dopaminergic synapse mmu04810   Regulation of actin cytoskeleton mmu04910   Insulin signaling pathway mmu04914   Progesterone-mediated oocyte maturation mmu04915   Estrogen signaling pathway mmu04917   Prolactin signaling pathway mmu04919   Thyroid hormone signaling pathway mmu04920   Adipocytokine signaling pathway mmu04922   Glucagon signaling pathway mmu04923   Regulation of lipolysis in adipocytes mmu04926   Relaxin signaling pathway mmu04929   GnRH secretion mmu04931   Insulin resistance mmu04932   Non-alcoholic fatty liver disease mmu04933   AGE-RAGE signaling pathway in diabetic complications mmu04935   Growth hormone synthesis, secretion and action mmu04936   Alcoholic liver disease mmu04973   Carbohydrate digestion and absorption mmu05010   Alzheimer disease mmu05017   Spinocerebellar ataxia mmu05132   Salmonella infection mmu05135   Yersinia infection mmu05142   Chagas disease mmu05145   Toxoplasmosis mmu05152   Tuberculosis mmu05160   Hepatitis C mmu05161   Hepatitis B mmu05162   Measles mmu05163   Human cytomegalovirus infection mmu05164   Influenza A mmu05165   Human papillomavirus infection mmu05166   Human T-cell leukemia virus 1 infection mmu05167   Kaposi sarcoma-associated herpesvirus infection mmu05168   Herpes simplex virus 1 infection mmu05169   Epstein-Barr virus infection mmu05170   Human immunodeficiency virus 1 infection mmu05200   Pathways in cancer mmu05205   Proteoglycans in cancer mmu05207   Chemical carcinogenesis - receptor activation mmu05208   Chemical carcinogenesis - reactive oxygen species mmu05210   Colorectal cancer mmu05211   Renal cell carcinoma mmu05212   Pancreatic cancer mmu05213   Endometrial cancer mmu05214   Glioma mmu05215   Prostate cancer mmu05218   Melanoma mmu05220   Chronic myeloid leukemia mmu05221   Acute myeloid leukemia mmu05222   Small cell lung cancer mmu05223   Non-small cell lung cancer mmu05224   Breast cancer mmu05225   Hepatocellular carcinoma mmu05226   Gastric cancer mmu05230   Central carbon metabolism in cancer mmu05231   Choline metabolism in cancer mmu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mmu05415   Diabetic cardiomyopathy mmu05417   Lipid and atherosclerosis mmu05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     23797 (Akt3)    04012 ErbB signaling pathway     23797 (Akt3)    04014 Ras signaling pathway     23797 (Akt3)    04015 Rap1 signaling pathway     23797 (Akt3)    04370 VEGF signaling pathway     23797 (Akt3)    04371 Apelin signaling pathway     23797 (Akt3)    04630 JAK-STAT signaling pathway     23797 (Akt3)    04668 TNF signaling pathway     23797 (Akt3)    04066 HIF-1 signaling pathway     23797 (Akt3)    04068 FoxO signaling pathway     23797 (Akt3)    04072 Phospholipase D signaling pathway     23797 (Akt3)    04071 Sphingolipid signaling pathway     23797 (Akt3)    04024 cAMP signaling pathway     23797 (Akt3)    04022 cGMP-PKG signaling pathway     23797 (Akt3)    04151 PI3K-Akt signaling pathway     23797 (Akt3)    04152 AMPK signaling pathway     23797 (Akt3)    04150 mTOR signaling pathway     23797 (Akt3)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     23797 (Akt3)   09143 Cell growth and death    04210 Apoptosis     23797 (Akt3)    04218 Cellular senescence     23797 (Akt3)   09144 Cellular community - eukaryotes    04510 Focal adhesion     23797 (Akt3)    04550 Signaling pathways regulating pluripotency of stem cells     23797 (Akt3)   09142 Cell motility    04810 Regulation of actin cytoskeleton     23797 (Akt3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     23797 (Akt3)    04613 Neutrophil extracellular trap formation     23797 (Akt3)    04620 Toll-like receptor signaling pathway     23797 (Akt3)    04625 C-type lectin receptor signaling pathway     23797 (Akt3)    04660 T cell receptor signaling pathway     23797 (Akt3)    04662 B cell receptor signaling pathway     23797 (Akt3)    04664 Fc epsilon RI signaling pathway     23797 (Akt3)    04666 Fc gamma R-mediated phagocytosis     23797 (Akt3)    04062 Chemokine signaling pathway     23797 (Akt3)   09152 Endocrine system    04910 Insulin signaling pathway     23797 (Akt3)    04922 Glucagon signaling pathway     23797 (Akt3)    04923 Regulation of lipolysis in adipocytes     23797 (Akt3)    04920 Adipocytokine signaling pathway     23797 (Akt3)    04929 GnRH secretion     23797 (Akt3)    04915 Estrogen signaling pathway     23797 (Akt3)    04914 Progesterone-mediated oocyte maturation     23797 (Akt3)    04917 Prolactin signaling pathway     23797 (Akt3)    04926 Relaxin signaling pathway     23797 (Akt3)    04935 Growth hormone synthesis, secretion and action     23797 (Akt3)    04919 Thyroid hormone signaling pathway     23797 (Akt3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     23797 (Akt3)   09154 Digestive system    04973 Carbohydrate digestion and absorption     23797 (Akt3)   09156 Nervous system    04725 Cholinergic synapse     23797 (Akt3)    04728 Dopaminergic synapse     23797 (Akt3)    04722 Neurotrophin signaling pathway     23797 (Akt3)   09158 Development and regeneration    04380 Osteoclast differentiation     23797 (Akt3)   09149 Aging    04211 Longevity regulating pathway     23797 (Akt3)    04213 Longevity regulating pathway - multiple species     23797 (Akt3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     23797 (Akt3)    05205 Proteoglycans in cancer     23797 (Akt3)    05207 Chemical carcinogenesis - receptor activation     23797 (Akt3)    05208 Chemical carcinogenesis - reactive oxygen species     23797 (Akt3)    05230 Central carbon metabolism in cancer     23797 (Akt3)    05231 Choline metabolism in cancer     23797 (Akt3)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     23797 (Akt3)   09162 Cancer: specific types    05210 Colorectal cancer     23797 (Akt3)    05212 Pancreatic cancer     23797 (Akt3)    05225 Hepatocellular carcinoma     23797 (Akt3)    05226 Gastric cancer     23797 (Akt3)    05214 Glioma     23797 (Akt3)    05221 Acute myeloid leukemia     23797 (Akt3)    05220 Chronic myeloid leukemia     23797 (Akt3)    05218 Melanoma     23797 (Akt3)    05211 Renal cell carcinoma     23797 (Akt3)    05215 Prostate cancer     23797 (Akt3)    05213 Endometrial cancer     23797 (Akt3)    05224 Breast cancer     23797 (Akt3)    05222 Small cell lung cancer     23797 (Akt3)    05223 Non-small cell lung cancer     23797 (Akt3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     23797 (Akt3)    05170 Human immunodeficiency virus 1 infection     23797 (Akt3)    05161 Hepatitis B     23797 (Akt3)    05160 Hepatitis C     23797 (Akt3)    05164 Influenza A     23797 (Akt3)    05162 Measles     23797 (Akt3)    05168 Herpes simplex virus 1 infection     23797 (Akt3)    05163 Human cytomegalovirus infection     23797 (Akt3)    05167 Kaposi sarcoma-associated herpesvirus infection     23797 (Akt3)    05169 Epstein-Barr virus infection     23797 (Akt3)    05165 Human papillomavirus infection     23797 (Akt3)   09171 Infectious disease: bacterial    05132 Salmonella infection     23797 (Akt3)    05135 Yersinia infection     23797 (Akt3)    05152 Tuberculosis     23797 (Akt3)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     23797 (Akt3)    05142 Chagas disease     23797 (Akt3)   09164 Neurodegenerative disease    05010 Alzheimer disease     23797 (Akt3)    05017 Spinocerebellar ataxia     23797 (Akt3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     23797 (Akt3)    05418 Fluid shear stress and atherosclerosis     23797 (Akt3)    05415 Diabetic cardiomyopathy     23797 (Akt3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     23797 (Akt3)    04932 Non-alcoholic fatty liver disease     23797 (Akt3)    04931 Insulin resistance     23797 (Akt3)    04933 AGE-RAGE signaling pathway in diabetic complications     23797 (Akt3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     23797 (Akt3)    01524 Platinum drug resistance     23797 (Akt3)    01522 Endocrine resistance     23797 (Akt3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmu01001]     23797 (Akt3) Enzymes [BR:mmu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      23797 (Akt3) Protein kinases [BR:mmu01001]  Serine/threonine kinases: AGC group   AKT/PKB family    23797 (Akt3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1 PH_11 Motif Other DBs NCBI-GeneID:  23797 NCBI-ProteinID:  NP_035915 MGI:  1345147 Ensembl:  ENSMUSG00000019699 UniProt:  Q9WUA6 Q8C6X4 LinkDB All DBs Position 1:complement(176847642..177091688) Genome browser AA seq 479 aa AA seqDB search MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDDDGMDGMDNERRPHFPQFSYSASGRE NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa aactggaggccaagatacttccttttgaagacagatggctcattcataggctataaggag aaacctcaagatgtggacttaccttatcccctcaacaacttctcagtggcaaaatgtcag ttaatgaaaacagaacgaccaaagccaaatacatttattatcagatgtcttcagtggacc actgttatagagagaacatttcatgtagatacaccagaggaaagagaagagtggacggaa gctatccaagccgtagccgaccgattgcagaggcaagaggaggagaggatgaattgtagc ccaacctcacagattgataatataggagaagaagagatggatgcgtctacaacccatcat aaaagaaagacgatgaatgattttgactatttgaaactactaggtaaaggcacttttggg aaagttattttggttcgagagaaggcaagtggaaaatactatgctatgaagattctgaag aaagaagtcattattgcaaaggatgaagtggcacacactcttactgaaagcagagtacta aagaacaccagacatccatttttaacatccttgaaatattccttccagacaaaagaccgt ttgtgttttgtgatggaatatgttaatggcggagagctgtttttccatttgtcgagagag cgagtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgctttggac tatctacattctggaaagattgtgtaccgtgatctcaagttggagaatttgatgctagat aaggatggccatataaaaattacggattttgggctttgcaaagaagggatcacagatgca gctaccatgaagacattctgtggcacaccagagtacctggcaccagaggtattagaagat aatgactatggccgagccgtggactggtggggcttaggtgttgtcatgtatgaaatgatg tgtggaaggttgcctttctacaaccaggatcatgagaaactctttgaattaatactaatg gaagacattaaattcccccgaacactctcttcagatgcaaaatcattgctttcagggctc ttgataaaggatccaaataaacgccttggtggagggccagatgatgcaaaagaaatcatg aggcatagttttttttctggagtaaactggcaagatgtatatgacaaaaagcttgtacct ccttttaagcctcaagtaacatctgaaacagacacccgatattttgatgaagaatttaca gctcagactattacaataacaccacctgaaaagtatgacgacgacggcatggacggcatg gacaacgagcggcggccacacttccctcagttctcctactctgcaagcggacgggaataa

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