KEGG   Mus musculus (house mouse): 11792
Entry
11792             CDS       T01002                                 
Symbol
Apex1, APE, Apex, HAP1, Ref-1
Name
(RefSeq) apurinic/apyrimidinic endonuclease 1
  KO
K10771  AP endonuclease 1 [EC:3.1.11.2]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03410  Base excision repair
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    11792 (Apex1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mmu03400]
    11792 (Apex1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters
    3.1.11.2  exodeoxyribonuclease III
     11792 (Apex1)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    AP endonucleases
     11792 (Apex1)
SSDB
Motif
Pfam: Exo_endo_phos Exo_endo_phos_2
Other DBs
NCBI-GeneID: 11792
NCBI-ProteinID: NP_033817
MGI: 88042
Ensembl: ENSMUSG00000035960
UniProt: P28352 Q544Z7
Structure
LinkDB
Position
14:51162406..51164645
AA seq 317 aa
MPKRGKKAAADDGEEPKSEPETKKSKGAAKKTEKEAAGEGPVLYEDPPDQKTSPSGKSAT
LKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWSA
PSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFESFVLVTAYVPNAGRGLVR
LEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFG
ELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIR
SKALGSDHCPITLYLAL
NT seq 954 nt   +upstreamnt  +downstreamnt
atgccaaagcggggaaagaaagcggcggccgacgacggggaagaacccaagtcggagcca
gagaccaagaagagtaagggggcagcaaagaaaaccgagaaggaggccgcgggagagggc
cctgtcctgtacgaggaccctccagatcagaaaacctcacccagtggcaaatctgccaca
ctcaagatatgctcctggaatgtggatgggcttcgagcctggattaaaaagaaaggtttg
gattgggtaaaggaagaagcaccagatatcttgtgcctccaagagaccaagtgctcggag
aacaaactcccggctgaactgcaagagctgcctggactcacccatcagtactggtcagct
ccgtcagacaaagaaggatacagtggtgtgggcctactttcccgccagtgcccgctaaaa
gtctcttatggcattggcgaggaagaacatgatcaagaaggccgggtgattgtggctgaa
tttgagtcctttgtcctggtaacagcctatgttcccaatgcaggcaggggtctggtaaga
ctggaataccgacagcgttgggatgaagccttccgaaagtttctaaaggacttggcttcc
agaaagcctcttgtgctatgtggggatctcaatgtggctcatgaagaaattgacctccgt
aaccccaaaggaaacaaaaagaatgctggctttactccccaggagcgccaaggttttggg
gaactgctacaagctgtaccattggctgacagcttccggcatctctaccccaacactgct
tacgcttacactttctggacttacatgatgaatgcccgctctaagaatgttggttggcgc
cttgattactttttgctttcccactctcttttacctgcattgtgtgacagcaagatccgg
tccaaggctcttggcagtgaccactgtcccatcaccctttacctagcactgtga

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