Mus musculus (house mouse): 13866
Help
Entry
13866 CDS
T01002
Symbol
Erbb2, Erbb-2, HER-2, HER2, Neu, c-erbB2, c-neu, l11Jus8, mKIAA3023
Name
(RefSeq) erb-b2 receptor tyrosine kinase 2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01521
EGFR tyrosine kinase inhibitor resistance
mmu01522
Endocrine resistance
mmu01524
Platinum drug resistance
mmu04010
MAPK signaling pathway
mmu04012
ErbB signaling pathway
mmu04020
Calcium signaling pathway
mmu04066
HIF-1 signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu04510
Focal adhesion
mmu04520
Adherens junction
mmu04530
Tight junction
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05206
MicroRNAs in cancer
mmu05212
Pancreatic cancer
mmu05213
Endometrial cancer
mmu05215
Prostate cancer
mmu05219
Bladder cancer
mmu05223
Non-small cell lung cancer
mmu05224
Breast cancer
mmu05226
Gastric cancer
mmu05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
13866 (Erbb2)
04012 ErbB signaling pathway
13866 (Erbb2)
04066 HIF-1 signaling pathway
13866 (Erbb2)
04020 Calcium signaling pathway
13866 (Erbb2)
04151 PI3K-Akt signaling pathway
13866 (Erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
13866 (Erbb2)
04520 Adherens junction
13866 (Erbb2)
04530 Tight junction
13866 (Erbb2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
13866 (Erbb2)
05206 MicroRNAs in cancer
13866 (Erbb2)
05205 Proteoglycans in cancer
13866 (Erbb2)
05230 Central carbon metabolism in cancer
13866 (Erbb2)
09162 Cancer: specific types
05212 Pancreatic cancer
13866 (Erbb2)
05226 Gastric cancer
13866 (Erbb2)
05219 Bladder cancer
13866 (Erbb2)
05215 Prostate cancer
13866 (Erbb2)
05213 Endometrial cancer
13866 (Erbb2)
05224 Breast cancer
13866 (Erbb2)
05223 Non-small cell lung cancer
13866 (Erbb2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
13866 (Erbb2)
01524 Platinum drug resistance
13866 (Erbb2)
01522 Endocrine resistance
13866 (Erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
13866 (Erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
13866 (Erbb2)
04090 CD molecules [BR:
mmu04090
]
13866 (Erbb2)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
13866 (Erbb2)
Protein kinases [BR:
mmu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
13866 (Erbb2)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
13866 (Erbb2)
CD molecules [BR:
mmu04090
]
Proteins
13866 (Erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Haspin_kinase
DUF5849
Kinase-like
PDGLE
GAPT
Motif
Other DBs
NCBI-GeneID:
13866
NCBI-ProteinID:
NP_001003817
MGI:
95410
Ensembl:
ENSMUSG00000062312
UniProt:
P70424
LinkDB
All DBs
Position
11:98303310..98328542
Genome browser
AA seq
1256 aa
AA seq
DB search
MELAAWCRWGFLLALLSPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQDIQEVQGYMLIAHNRVKHVPLQRLRIVRGTQLFEDKYALAVLDNR
DPLDNVTTAAPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVLRKNNQL
APVDMDTNRSRACPPCAPTCKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCCHEQ
CAAGCTGPKHSDCLACLHFNHSGICELHCPALITYNTDTFESMLNPEGRYTFGASCVTTC
PYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCAGVCYGLGMEHLRGARAITSD
NIQEFAGCKKIFGSLAFLPESFDGNPSSGVAPLKPEHLQVFETLEEITGYLYISAWPESF
QDLSVFQNLRVIRGRILHDGAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNTHLCFVNT
VPWDQLFRNPHQALLHSGNRPEEACGLEGLVCNSLCARGHCWGPGPTQCVNCSQFLRGQE
CVEECRVWKGLPREYVRGKHCLPCHPECQPQNSSETCYGSEADQCEACAHYKDSSSCVAR
CPSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPVTFIIATVV
GVLLFLIIVVVIGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAVPNQAQMRILKETE
LRKLKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGS
PYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEV
RLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRF
THQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCW
MIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLEDDDMGELVD
AEEYLVPQQGFFSPDPALGTGSTAHRRHRSSSARSGGGELTLGLEPSEEEPPRSPLAPSE
GAGSDVFDGDLAVGVTKGLQSLSPHDLSPLQRYSEDPTLPLPPETDGYVAPLACSPQPEY
VNQPEVRPQSPLTPEGPPPPIRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAP
RAGTASQPHPSPAFSPAFDNLYYWDQNSSEQGPPPSTFEGTPTAENPEYLGLDVPV
NT seq
3771 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgttgggggttcctcctcgccctcctgtcccccggagcc
gcgggtacccaagtgtgtaccggtaccgacatgaagttgcgactccctgccagtcctgag
acccacctggacatgcttcgccacctctaccagggctgtcaggtggtgcagggcaatttg
gagcttacctacctgcccgccaatgccagcctctcattcctgcaggacatccaggaagtc
cagggatacatgctcatcgctcacaaccgagtgaaacacgtcccactgcagaggttgcgc
atcgtgagagggactcagctctttgaggacaagtatgccctggctgtgctagacaaccga
gaccctttggacaacgtcaccaccgccgccccaggcagaaccccagaagggctgcgggag
ctgcagcttcgaagtctcacagagatcttgaagggaggagttttgatccgtgggaaccct
cagctctgctaccaggacatggttttgtggaaggatgtcctccgtaagaataaccagctg
gctcctgtcgacatggacaccaatcgttcccgggcctgtccaccttgtgccccaacctgc
aaagacaatcactgttggggtgagagtcctgaagactgtcagatcttgactggcaccatc
tgtactagtggctgtgcccggtgcaagggccggctgcccactgactgttgccatgagcag
tgtgctgcaggctgcacgggtcccaagcattctgactgcctggcctgcctccacttcaat
catagtggtatctgtgagctgcactgcccggccctcatcacctacaacacagacaccttc
gagtccatgctcaaccctgagggtcgctacacctttggtgccagctgtgtgaccacctgc
ccctacaactacctctccacggaagtgggatcctgcactctggtctgtcccccgaacaac
caagaggtcacagctgaggacggaacacagcggtgtgagaaatgcagcaagccctgtgct
ggagtatgctatggtctgggcatggagcacctccgaggggcgagggccatcaccagtgac
aatatccaggagtttgctggctgcaagaagatctttgggagcctggcatttttgccggag
agctttgatgggaacccctcctccggcgttgccccactgaagccagagcatctccaagtg
ttcgaaaccctggaggagatcacaggttacctatacatttcagcatggccagagagcttc
caagacctcagtgtcttccagaaccttcgggtcattcggggacggattctccatgatggt
gcttactcattgacgttgcaaggcctggggattcactcactggggctacgctcactgcgg
gagctgggcagtggattggctctcattcaccgcaacacccatctctgctttgtaaacact
gtaccttgggaccagctcttccggaacccgcaccaggccctactccacagtgggaaccgg
ccagaagaggcatgtggtcttgagggcttggtctgtaactcactgtgtgcccgtgggcac
tgctgggggccagggcccacccagtgtgtcaactgcagtcagttcctccggggccaggag
tgtgtggaggagtgccgagtatggaaggggctccccagggagtatgtgaggggcaagcac
tgtctgccatgccaccccgagtgtcagcctcaaaacagctcggagacctgctatggatcg
gaggctgaccagtgtgaggcttgtgcccactacaaggactcatcttcctgtgtggctcgc
tgccccagtggtgtgaagccagacctctcctacatgcctatctggaagtacccggatgag
gagggcatatgtcagccatgccccatcaactgcacccactcatgtgtggacctggacgaa
cgaggctgcccagcagagcagagagccagcccagtgacattcatcattgcaactgtggtg
ggcgtcctgttgttcctgatcatagtggtggtcattggaatcctaatcaaacgaaggcga
cagaagatccggaagtataccatgcgtaggctgctgcaggagaccgagctggtggagccg
ctgacgcccagtggagctgtgcccaaccaggctcagatgcggatcctaaaggagacagag
ctaaggaagctgaaggtgcttgggtcaggagccttcggcactgtctacaagggcatctgg
atcccagatggggagaacgtgaaaatccccgtggccatcaaggtgttgagggaaaacaca
tctcctaaagctaacaaagaaatcctagatgaagcgtacgtcatggctggtgtgggttct
ccatatgtgtcccgcctcctgggcatctgcctgacatccacagtgcagctggtgacacag
cttatgccctatggctgccttctggaccatgtccgagaacaccgaggtcgcttaggctcc
caggacctgctcaactggtgtgttcagattgccaaggggatgagctacctggaggaagtt
cggcttgttcacagggacctagctgcccgaaacgtgctagtcaagagtcccaaccacgtc
aagattaccgacttcgggctggcacggctgctggacattgatgagactgaataccatgca
gatgggggcaaggtgcccatcaagtggatggcattggaatctattctcagacgccggttc
acccatcagagtgatgtgtggagctatggtgtgactgtgtgggagctgatgacctttggg
gccaaaccttacgatgggatcccagctcgggagatccctgatttgctggagaagggagaa
cgcctacctcagcctccaatctgcaccatcgacgtctacatgatcatggtcaaatgttgg
atgattgactccgaatgtcgcccgagattccgggagttggtatcagaattctcccgtatg
gcaagggacccccagcgctttgtggtcatccagaacgaggacttaggcccctccagcccc
atggacagcaccttctaccgttcactgctggaggatgatgacatgggggagctggtcgat
gctgaagagtacctggtaccccagcagggattcttctccccagaccctgccctaggtact
gggagcacagcccaccgcagacaccgcagctcgtcggccaggagtggcggtggtgagctg
acactgggcctggagccctcggaagaagagccccccagatctccactggctccctccgaa
ggggctggctccgatgtgtttgatggtgacctggcagtgggggtaaccaaaggactgcag
agcctctctccacatgacctcagccctctacagcggtacagtgaggatcccacattacct
ctgccccccgagactgatggctacgttgctcccctggcctgcagcccccagcccgagtat
gtgaaccagccagaggttcggcctcagtctcccttgaccccagagggtcctccgcctccc
atccgacctgctggtgctactctagaaagacccaagactctctctcctgggaaaaatggg
gttgtcaaagacgtttttgcctttgggggtgctgtggagaaccctgaatacttagcaccc
agagcaggcactgcctctcagccccacccttctcctgccttcagcccagcctttgacaac
ctctattactgggaccagaactcatcggagcagggtcctccaccaagtacctttgaaggg
acccccactgcagagaaccctgagtacctaggcctggatgtgccagtatga
Mus musculus (house mouse): 13867
Help
Entry
13867 CDS
T01002
Symbol
Erbb3, C76256, Erbb-3, Erbb3r, Her3
Name
(RefSeq) erb-b2 receptor tyrosine kinase 3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01521
EGFR tyrosine kinase inhibitor resistance
mmu04010
MAPK signaling pathway
mmu04012
ErbB signaling pathway
mmu04020
Calcium signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu05205
Proteoglycans in cancer
mmu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
13867 (Erbb3)
04012 ErbB signaling pathway
13867 (Erbb3)
04020 Calcium signaling pathway
13867 (Erbb3)
04151 PI3K-Akt signaling pathway
13867 (Erbb3)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
13867 (Erbb3)
05205 Proteoglycans in cancer
13867 (Erbb3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
13867 (Erbb3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
13867 (Erbb3)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
13867 (Erbb3)
Protein kinases [BR:
mmu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
13867 (Erbb3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
CD34_antigen
APH
Motif
Other DBs
NCBI-GeneID:
13867
NCBI-ProteinID:
NP_034283
MGI:
95411
Ensembl:
ENSMUSG00000018166
UniProt:
Q61526
LinkDB
All DBs
Position
10:complement(128403392..128425504)
Genome browser
AA seq
1339 aa
AA seq
DB search
MSAIGTLQVLGFLLSLARGSEMGNSQAVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVKNNG
GNCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCNGRCFGPNPNQCCHDECAGGCSGPQD
TDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQTF
CVRACPADKMEVDKNGLKMCEPCRGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPAEE
RLDIKYNRPLGECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEP
REFVHEAHCFSCHPECQPMEGTSTCNGSGSDACARCAHFRDGPHCVNSCPHGILGAKGPI
YKYPDAQNECRPCHENCTQGCKGPELQDCLGQAEVLMSKPHLVIAVTVGLTVIFLILGGS
FLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVFGT
VHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSS
LQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVML
KSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVW
ELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELA
NEFTRMARDPPRYLVIKRASGPGIPPAAEPSALSTKELQDAELEPDLDLDLDVEVEEEGL
ATTLGSALSLPTGTLTRPRGSQSLLSPSSGYMPMNQSNLGEACLDSAVLGGREQFSRPIS
LHPIPRGRQTSESSEGHVTGSEAELQERVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPV
TPLSPPGLEEEDGNGYVMPDTHLRGTSSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRK
RRGSPARPPRPGSLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDEDYEYM
NRRRGAGGSGGDYAAMGACPAAEQGYEEMRAFQGPGHQAPHVRYARLKTLRSLEATDSAF
DNPDYWHSRLFPKANAQRI
NT seq
4020 nt
NT seq
+upstream
nt +downstream
nt
atgagtgcgattgggactctgcaggtgctgggtttccttctcagcctggcccggggttcc
gagatgggcaactctcaggcagtatgtcctgggactctaaacgggctgagtgtgaccggc
gatgctgacaaccagtaccagacactgtacaaactctatgagaagtgtgaggtggtcatg
ggtaacctggagattgtgcttacgggacacaatgctgatctttccttcctgcaatggatc
cgagaagtgacaggctatgtactggtggccatgaatgaattctctgtactgcccttacct
aacctccgagtggtccggggaacccaggtctacgatgggaagtttgccatctttgtcatg
ttgaactacaataccaactccagccatgctctgcgccagctccggttcactcagcttact
gagattctgttagggggcgtttacattgagaagaatgacaaactttgccacatggataca
attgactggagggacatcgtgagggttccagacgctgagatagtggtgaagaacaacggg
gggaactgtccaccctgtcacgaagtctgcaaggggcgatgctgggggcctggaccagaa
gactgccagatattgaccaagaccatctgtgcccctcagtgtaacggtcgctgcttcggg
cccaatcctaaccagtgctgccacgatgaatgtgcaggtggctgctctggaccccaggac
acagattgcttcgcctgccgacacttcaatgacagtggtgcctgtgtgcccaggtgtcca
gcgccccttgtgtacaacaagctaacgttccagcttgagcccaacccccatatcaagtat
cagtacggaggagtctgtgttgccagttgtccccataactttgtggtggatcagacattt
tgtgtcagggcttgtcctgctgacaagatggaagtagataagaatggactcaagatgtgt
gagccttgcagagggctgtgcccaaaagcctgtgaggggacgggctctggaagccgctac
cagaccgtggactctagcaatatcgatgggttcgtgaactgtaccaagatcctgggcaac
ctggacttcctcatcactggcctcaatggtgacccctggcacaagatccctgcactggac
ccggaaaagctcaatgttttcaggacagtccgggagattacaggctacctaaacatccag
tcctggccccctcacatgcacaacttcagtgttttttccaacctgacgaccatcgggggc
agaagcctctacaatcggggcttctccttgttgatcatgaagaacttgaatgtcacgtct
ctgggcttccggtccctgaaggaaattagtgctgggcgtgtctacataagtgccaatcag
caactttgttaccaccactctctgaactggaccagacttctgcgggggcccgcagaggag
agacttgacatcaagtacaaccggcctctgggagaatgcgtggcagagggcaaagtgtgt
gatccactgtgctcctctgggggatgctggggcccaggccctggtcagtgcttgtcttgt
cgaaactacagccgggaaggtgtctgtgtgactcactgcaacgttctgcaaggggaaccc
cgagagtttgttcatgaggctcattgcttctcctgccatccagaatgccagcccatggag
ggcaccagcacgtgcaatggctcgggctccgacgcttgtgctcgatgcgcccattttcgt
gatgggccccactgtgtgaacagctgcccccatggaatcctaggtgccaaaggtccaatc
tacaaatatccagatgctcagaatgagtgccggccctgccacgagaactgcacccaaggg
tgtaagggaccagaactacaagactgtttaggccaagcagaggtattaatgagcaaacca
cacctggtcatagcggtgacagtaggactgactgtgatcttcctgattctgggaggctct
tttctctattggcgtggacgcaggattcagaataaaagggctatgagacgctacttggag
cggggtgagagcatcgagcctctggacccaagcgagaaggcaaacaaagtcttggctaga
atcttcaaagagacagagctgaggaaacttaaggtgcttggctctggtgtctttggaact
gtacacaaggggatttggattcccgagggtgaatccatcaagattccagtctgcattaaa
gtcatcgaggacaagagtgggcggcagagttttcaggctgtgactgatcacatgctggcc
gtcggcagcctggaccatgcccacattgtacggctgctgggactgtgcccagggtcatct
ctgcagcttgtcactcagtacttgcctctgggctctctccttgatcatgtaagacagcac
cgtgagacactgggaccacagctgctgctcaactggggagtacaaattgccaagggtatg
tattacctcgaggaacacagcatggtgcatagggaccttgcgctccggaatgtgatgctt
aagtcaccgagtcaagtccaggtggcagattttggtgtggctgacttgctgccgccagat
gacaagcagttactacacagtgaggccaagactccaattaaatggatggcccttgagagt
atccactttgggaaatacacacaccagagtgatgtctggagttacggtgtaaccgtttgg
gagttgatgaccttcggggcagagccctacgcagggctacgactggctgaaataccagac
ctgctggagaagggagagcggttagcacagccccagatctgcaccattgacgtctacatg
gtcatggtcaagtgttggatgattgacgagaatattcgcccaacctttaaagaactggcc
aatgagtttaccaggatggcccgggacccaccaaggtatctggtcatcaagagagcgagt
gggcctggaatacctcctgcagcagagccatctgctctgagcaccaaagagttgcaggat
gcagagctggagccagacctggacctcgacctagacgtggaggtagaagaggagggcctg
gcgaccacactgggttctgccctcagcttgcctacaggaacgcttacccggccacgtggg
agccagagtcttttaagtccttcgtctggatacatgcccatgaaccagagcaaccttggg
gaggcttgtctggattctgcggttttggggggtcgcgaacagttctcccgtcccatctct
ctgcacccgatcccacgggggcgtcaaacgtcagagtcatcagagggccatgtgacgggc
tctgaggctgaactccaagagagagtatcaatgtgtaggagccggagccggagccggagc
ccacggccacgtggggacagtgcctaccattcgcagcgacacagcctgcttactcccgtc
accccgctctccccaccagggttagaggaagaggatggcaatggttatgtcatgccagat
acgcacctcagaggtacatcctcttcccgggaaggcaccctttcgtcagtaggtctcagt
tctgtgctgggtaccgaagaggaagatgaagatgaggagtatgaatacatgaaccggaag
aggaggggtagcccggctcggccccccagacctggttccctggaagagctgggctatgag
tacatggatgtgggttcagacctcagtgcttctctgggcagtacgcagagttgcccactc
catcccatggccatcgtgccctctgctggcacgactccagatgaggactatgaatacatg
aaccgcaggcgtggtgcgggcggttccggaggggattatgcagctatgggggcctgccca
gcagctgaacaagggtatgaggaaatgcgagctttccaggggcctggacatcaagccccc
catgttcgttatgcccgcctcaaaactctgcgtagtttagaagccactgactccgccttt
gacaaccccgattactggcatagcaggcttttccctaaggctaacgcccagagaatttga
Mus musculus (house mouse): 13869
Help
Entry
13869 CDS
T01002
Symbol
Erbb4, Her4, c-erbB-4
Name
(RefSeq) erb-b2 receptor tyrosine kinase 4
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04010
MAPK signaling pathway
mmu04012
ErbB signaling pathway
mmu04020
Calcium signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu05014
Amyotrophic lateral sclerosis
mmu05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
13869 (Erbb4)
04012 ErbB signaling pathway
13869 (Erbb4)
04020 Calcium signaling pathway
13869 (Erbb4)
04151 PI3K-Akt signaling pathway
13869 (Erbb4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
13869 (Erbb4)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
13869 (Erbb4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
13869 (Erbb4)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
13869 (Erbb4)
Protein kinases [BR:
mmu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
13869 (Erbb4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
Haspin_kinase
Kinase-like
APH
ABC1
DUF3951
Motif
Other DBs
NCBI-GeneID:
13869
NCBI-ProteinID:
NP_034284
MGI:
104771
Ensembl:
ENSMUSG00000062209
UniProt:
Q61527
LinkDB
All DBs
Position
1:complement(68071063..69147756)
Genome browser
AA seq
1292 aa
AA seq
DB search
MKLATGLWVWGSLLMAAGTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVST
NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
INQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYD
GEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG
LFILVIMALTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRTRIDSNRNQFVYQDGGFATQQGMPMPYRATTSTIPEAPVAQG
ATAEMFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERNPRGELDEEGYMTPMHD
KPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAEDEYVNEPLYLNTFANAL
GSAEYMKNSVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRP
IVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV
NT seq
3879 nt
NT seq
+upstream
nt +downstream
nt
atgaagctggcgacgggactctgggtctgggggagccttctgatggcagcggggaccgtc
cagcccagcgcttctcagtcagtgtgcgcaggaacagagaacaaactgagctctctctct
gacctggaacagcagtaccgagccttgcgcaaatactatgaaaactgcgaggtagtcatg
ggcaacctggagatcaccagcatcgagcacaaccgggacctctccttcctgcggtctatc
cgagaagtcacaggctacgtcctggtggccctcaaccagtttcgttacttgcctctggag
aatttacgcattattcgtgggacaaaactatatgaagatcgctatgccttagcgatattc
ttaaactacaggaaagatggcaactttggactccaagaacttggattaaagaacctgacc
gaaatactaaatggtggagtctatgtagaccagaacaaattcctatgttatgctgacact
atacactggcaagatattgttcggaatccatggccttccaacatgactctggtgtcaaca
aatggaagttctggatgtggaagatgccataagtcttgcactggccgatgctggggaccc
acagaaaatcactgccagaccttgaccagaactgtgtgtgctgaacaatgtgatggcagg
tgctatggaccctacgttagtgactgctgccatcgagaatgtgctggaggctgctcagga
ccaaaggacactgactgctttgcctgcatgaacttcaatgacagtggagcctgcgttact
caatgtccccaaacatttgtctacaatccaaccacctttcaactggaacacaacttcaat
gcaaagtacacgtatggagcattctgtgttaagaaatgtccacataacttcgtggtagat
tccagttcttgtgtacgagcctgccctagttctaagatggaagtagaagaaaatgggatt
aaaatgtgtaagccttgcaccgatatttgccccaaagcatgtgatggaatcggcacggga
tcactgatgtctgctcagactgtggattcaagtaacattgacaaattcataaactgcaca
aagatcaatggcaatctcatctttcttgtcactggcattcatggagacccttacaatgct
attgacgccatagatccagagaaactgaatgtctttcggactgtcagagaaataacaggt
ttcctgaacatacagtcttggcccccaaatatgacagatttcagtgttttctccaacctc
gtcacaattggaggaagagtcctctacagtggtctctcattgctgatcctcaaacaacaa
ggtatcacttccctacagttccagtctctgaaggaaatcagtgcgggcaatatctacatc
actgacaacagcaacctgtgttattaccataccattaactggacaacactcttcagcacc
attaaccagagaatagtgatccgagataacagaagagctgagaattgtactgctgaaggc
atggtatgcaaccacctgtgttcaaatgatggttgttggggacctgggccggaccagtgc
ctgtcatgtcggcgcttcagcaggggaaagatctgcatagagtcttgcaacctttatgat
ggggaatttcgagagtttgaaaacggctccatctgtgttgagtgtgactcccagtgtgag
aaaatggaagatggactcctcacatgccatggaccgggacctgacaactgcacaaagtgc
tctcattttaaggatggtccaaactgtgtggagaaatgtccagatggcctacagggagca
aacagtttcatttttaagtatgcagatcaggatcgggagtgccacccttgccatccaaac
tgcacccaggggtgtaacggtcccactagtcatgactgcatttactacccatggacgggc
cattccactttaccacaacacgctagaactccactgattgcagccggagtcattggaggc
ctcttcatcctggtgatcatggctttgacatttgctgtctatgtcagaagaaagagcatc
aaaaagaaacgtgctttgaggagattcctggagacagagctggtagagcccttaactccc
agtggcacggcacccaatcaagctcaacttcgcattttgaaggaaaccgaactaaagagg
gtaaaggtccttggctcgggagcttttggaaccgtttataaaggtatttgggtgcctgaa
ggtgaaacagtgaaaatccctgtggctataaagatcctcaatgaaacaactggccccaaa
gccaacgtggagttcatggatgaggctctgatcatggcaagtatggatcacccacaccta
gttcgcctattgggagtgtgtctgagtcccactatccagttggttacgcagctgatgccg
catggctgcctactggactatgttcatgaacacaaggataacattggatcacagctgctg
ttgaactggtgtgtccagattgctaagggaatgatgtacctagaagaaagacggcttgtt
catcgggatctggcagcccgcaatgtcttagtgaaatctccaaatcatgttaaaatcaca
gattttggactggcccggctcttggaaggagatgaaaaagaatacaatgctgatggtggc
aagatgccaattaaatggatggctctggaatgtatacattataggaaattcacacatcaa
agtgatgtttggagctatggcgtcactatatgggaactgatgacctttggaggaaagccc
tatgatggaattccaacccgagaaatccccgatttactggagaaaggagagcgtctgcct
cagcctcccatctgcactattgatgtttacatggtcatggtcaaatgttggatgatcgat
gctgacagcagacctaaattcaaagaactggctgctgagttttcaagaatggctagagac
cctcaaagatacctagttattcagggtgatgatcgtatgaagcttcccagtccaaatgac
agcaaattcttccagaatctcttggatgaagaggatttggaagacatgatggatgctgag
gaatatttggtcccccaggctttcaacatacctcctcccatctacacatccagaacaaga
attgactccaataggaatcagtttgtgtaccaagatgggggctttgctacacaacaagga
atgcccatgccctacagagccacaaccagcaccataccagaggctccagtagctcagggt
gcaacggctgagatgtttgatgactcctgctgtaatggtaccctacgaaagccagtggca
ccccatgtccaagaggacagtagcactcagaggtatagtgctgatcccacagtgttcgcc
ccagaacggaatcctcgaggagaactggatgaagaaggctacatgactccaatgcatgac
aagcccaaacaagaatatctgaatcctgtggaagagaacccttttgtgtcccgaaggaag
aatggagatcttcaagctttagataatccggagtatcacagtgcttccagcggtccaccc
aaggcggaggatgaatacgtgaatgagcctctatacctcaacaccttcgccaatgccttg
gggagtgcagagtacatgaaaaacagtgtactgtctgtgccagagaaagccaagaaagca
tttgacaaccccgactactggaaccacagcctgccaccccggagcacccttcagcaccca
gactacctgcaggaatacagcacaaaatatttttataaacagaatggacggatccgcccc
attgtggcagagaatcctgagtacctctcggagttctcgctgaagcctggcactatgctg
ccccctccgccctacagacaccggaatactgtggtgtga
DBGET
integrated database retrieval system
