Mus musculus (house mouse): 15170
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Entry
15170 CDS
T01002
Symbol
Ptpn6, 70Z-SHP, Hcph, PTPTY-42, Ptp1C, SH-PTP1, SHP-1, hcp, me
Name
(RefSeq) protein tyrosine phosphatase, non-receptor type 6
KO
K05697
tyrosine-protein phosphatase non-receptor type 6 [EC:
3.1.3.48
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04520
Adherens junction
mmu04630
JAK-STAT signaling pathway
mmu04650
Natural killer cell mediated cytotoxicity
mmu04660
T cell receptor signaling pathway
mmu04662
B cell receptor signaling pathway
mmu05140
Leishmaniasis
mmu05205
Proteoglycans in cancer
mmu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
15170 (Ptpn6)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
15170 (Ptpn6)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
15170 (Ptpn6)
04660 T cell receptor signaling pathway
15170 (Ptpn6)
04662 B cell receptor signaling pathway
15170 (Ptpn6)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
15170 (Ptpn6)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
15170 (Ptpn6)
09174 Infectious disease: parasitic
05140 Leishmaniasis
15170 (Ptpn6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mmu01009
]
15170 (Ptpn6)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
15170 (Ptpn6)
Protein phosphatases and associated proteins [BR:
mmu01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
15170 (Ptpn6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
DSPc
Y_phosphatase3
PTPlike_phytase
HGAL
Motif
Other DBs
NCBI-GeneID:
15170
NCBI-ProteinID:
NP_038573
MGI:
96055
Ensembl:
ENSMUSG00000004266
Vega:
OTTMUSG00000038210
UniProt:
P29351
Q3UB72
LinkDB
All DBs
Position
6:complement(124697670..124715672)
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AA seq
595 aa
AA seq
DB search
MVRWFHRDLSGPDAETLLKGRGVPGSFLARPSRKNQGDFSLSVRVDDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGILQDRDGTIIHLKYPLNCSDPTSERWYHGHISGGQA
ESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAGPGSPLRVTHIKVMCEGGRYTVGG
SETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSD
YINANYVKNQLLGPDENSKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEKGRNK
CVPYWPEVGTQRVYGLYSVTNSREHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQKGQESEYGNIT
YPPAVRSAHAKASRTSSKHKEEVYENVHSKSKKEEKVKKQRSADKEKNKGSLKRK
NT seq
1788 nt
NT seq
+upstream
nt +downstream
nt
atggtgaggtggtttcaccgggacctcagcgggcctgatgcagagaccctgctgaagggc
cggggagtccctgggagcttcctggctcggcccagccgcaagaaccagggtgacttctcc
ctctcagtcagggtggatgatcaggtgactcatattcggatccagaactcaggggacttc
tatgacctgtacggaggggagaagtttgcgacgctgacagagctggtcgagtattacacg
cagcagcagggcatcctgcaggaccgagatggcaccatcatccaccttaagtacccactg
aactgctcggaccccaccagtgagaggtggtaccacggccacatatctggagggcaggcg
gagtcactgctgcaggccaagggcgagccctggacatttcttgtgcgtgagagtctcagc
caacctggtgattttgtgctctctgtgctcaatgaccagcccaaggctggcccaggttcc
ccgctcagggtcactcatatcaaggttatgtgtgagggtggacgctatactgtgggtggc
tcagagacgtttgacagcctcacagacctggtggagcacttcaagaagacagggattgag
gaggcctcgggtgcctttgtctacctgcggcagccttactacgctactcgggtaaacgca
gctgacattgagaatcgggtcttggaactgaacaagaagcaggagtcggaggacacagcc
aaggctggcttctgggaggagtttgagagtctacaaaagcaggaggtaaagaatctacac
caacgtctggaagggcagcggccagagaacaagagcaagaaccgctacaagaacattctt
ccctttgaccacagccgagtgatcctgcagggacgtgacagtaacatcccaggctctgac
tacatcaatgccaactacgtgaagaaccagctgctaggtccagatgagaactctaagacc
tacatcgccagccagggctgtctggatgccacagtcaatgacttctggcagatggcttgg
caggagaacactcgtgtcatcgtcatgactaccagagaggtggagaaaggccggaacaaa
tgtgtcccatactggcccgaggtgggcactcagcgtgtctatggtctctactctgtgacc
aacagtagggagcatgacacagcagaatacaaactgcgaacattacagatctccccacta
gacaatggggacctggttcgggagatatggcactaccagtacctgagctggcctgaccat
ggggttcccagtgagcctgggggtgtcctcagctttctggatcagatcaaccagcgacag
gaaagtttgcctcatgcagggcccatcattgtgcattgcagcgctggcatcggccgcacg
ggcaccatcatcgtcattgatatgcttatggaaagcatctccaccaaggggctagactgt
gacattgatatccagaagaccatccagatggtacgagcacagcgctccggcatggtgcag
accgaggcccagtacaagtttatttacgtggccattgcccagttcatcgaaacgaccaag
aagaaactggagatcatacaatcccagaagggccaggagtcggagtatgggaatatcacg
taccctcccgctgtgaggagtgcccacgccaaagcctcgcgtacttcctccaagcacaag
gaggaggtgtacgaaaacgtgcatagcaagagcaagaaggaagagaaagtaaagaagcag
cggtcggcagacaaggagaagaacaaaggttctctcaagaggaagtga
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