Mus musculus (house mouse): 18128 Help Entry 18128             CDS       T01002                                  Symbol Notch1, 9930111A19Rik, Mis6, N1, Tan1, lin-12 Name (RefSeq) notch 1   KO K02599   Notch 1 Organism mmu  Mus musculus (house mouse) Pathway mmu01522   Endocrine resistance mmu04330   Notch signaling pathway mmu04658   Th1 and Th2 cell differentiation mmu04919   Thyroid hormone signaling pathway mmu05020   Prion disease mmu05165   Human papillomavirus infection mmu05200   Pathways in cancer mmu05206   MicroRNAs in cancer mmu05224   Breast cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     18128 (Notch1)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     18128 (Notch1)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     18128 (Notch1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     18128 (Notch1)    05206 MicroRNAs in cancer     18128 (Notch1)   09162 Cancer: specific types    05224 Breast cancer     18128 (Notch1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     18128 (Notch1)   09164 Neurodegenerative disease    05020 Prion disease     18128 (Notch1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     18128 (Notch1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank NOD Notch NODP Ank_4 Ank_5 Ank_3 EGF_3 JAG1-like_EGF2 Gurken_M Motif Other DBs NCBI-GeneID:  18128 NCBI-ProteinID:  NP_032740 MGI:  97363 Ensembl:  ENSMUSG00000026923 UniProt:  Q01705 Structure PDBPDBj LinkDB All DBs Position 2:complement(26347914..26393834) Genome browser AA seq 2531 aa AA seqDB search MPRLLTPLLCLTLLPALAARGLRCSQPSGTCLNGGRCEVANGTEACVCSGAFVGQRCQDS NPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLL TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFESSYICRCPPGFHGPTCRQDVN ECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTT HECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCE CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGA NPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMP GYEGVYCEINTDECASSPCLHNGHCMDKINEFQCQCPKGFNGHLCQYDVDECASTPCKNG AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCQPGYTGHHC ETNINECHSQPCRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKID GYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNEC NSNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKN SGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNTNGSYRCLCQAGYT GRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCQNGANC TDCVDSYTCTCPVGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQY DVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQ YHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYTGS YCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCID LTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFV GERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGHTGRRCESVINGCRGKPCKNGG VCAVASNTARGFICRCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGSFTG PECQFPASSPCVGSNPCYNQGTCEPTSENPFYRCLCPAKFNGLLCHILDYSFTGGAGRDI PPPQIEEACELPECQVDAGNKVCNLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYF SDGHCDSQCNSAGCLFDGFDCQLTEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLD CAEHVPERLAAGTLVLVVLLPPDQLRNNSFHFLRELSHVLHTNVVFKRDAQGQQMIFPYY GHEEELRKHPIKRSTVGWATSSLLPGTSGGRQRRELDPMDIRGSIVYLEIDNRQCVQSSS QCFQSATDVAAFLGALASLGSLNIPYKIEAVKSEPVEPPLPSQLHLMYVAAAAFVLLFFV GCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASDGALMDDNQ NEWGDEDLETKKFRFEEPVVLPDLSDQTDHRQWTQQHLDAADLRMSAMAPTPPQGEVDAD CMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGET ALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILLRNRATDLDA RMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKN GANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIV RLLDEYNLVRSPQLHGTALGGTPTLSPTLCSPNGYLGNLKSATQGKKARKPSTKGLACGS KEAKDLKARRKKSQDGKGCLLDSSSMLSPVDSLESPHGYLSDVASPPLLPSPFQQSPSMP LSHLPGMPDTHLGISHLNVAAKPEMAALAGGSRLAFEPPPPRLSHLPVASSASTVLSTNG TGAMNFTVGAPASLNGQCEWLPRLQNGMVPSQYNPLRPGVTPGTLSTQAAGLQHSMMGPL HSSLSTNTLSPIIYQGLPNTRLATQPHLVQTQQVQPQNLQLQPQNLQPPSQPHLSVSSAA NGHLGRSFLSGEPSQADVQPLGPSSLPVHTILPQESQALPTSLPSSMVPPMTTTQFLTPP SQHSYSSSPVDNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNISDWSEGISSPPTTMP SQITHIPEAFK NT seq 7596 nt NT seq  +upstreamnt  +downstreamnt atgccacggctcctgacgcccttgctctgcctaacgctgctgcccgcgctcgccgcaaga ggcttgagatgctcccagccaagtgggacctgcctgaatggagggaggtgcgaagtggcc aacggcactgaagcctgtgtctgcagcggagcctttgtgggccaacgatgccaggactcc aatccttgcctcagcacaccgtgtaagaatgctggaacgtgccacgttgtggaccatggt ggcactgtggattatgcctgcagctgtcccctgggtttctctgggcccctctgcctgaca cctctggacaacgcctgcctggccaacccctgccgcaatgggggcacctgtgacctgctc actctcacagagtacaagtgccgctgcccaccagggtggtcaggaaaatcatgtcagcag gctgacccctgtgcctccaacccctgtgccaatggtggccagtgcctgccctttgagtct tcatacatctgtcgctgcccgcctggcttccatggccccacctgcaggcaagatgttaat gagtgcagccagaaccctgggctgtgccgccatggaggcacctgccacaatgagatcggc tcctatcgctgtgcctgccgtgccacccatactggtccccactgtgaactgccctatgtg ccctgcagcccctcaccctgccagaatggaggcacctgccgtcctacaggggacaccacc cacgagtgtgcctgcttgccaggttttgctggacagaactgtgaagaaaatgtggatgac tgtccaggaaacaactgcaagaatgggggtgcctgtgtggacggcgtgaatacctacaat tgccgctgcccaccggagtggacgggtcagtactgtacagaggatgtggacgaatgtcag ctcatgcccaatgcctgccagaatggcggaacctgccacaacacacacggcggctacaac tgtgtgtgtgtcaatgggtggactggcgaggactgcagtgagaacattgatgactgtgcc agtgccgcctgtttccagggtgccacttgccacgaccgtgtggcttccttctactgcgaa tgtccgcatgggcgcacaggtctgctgtgccacctcaacgatgcgtgcatcagcaacccc tgcaacgagggctccaactgtgacaccaaccctgtcaacggcaaagccatctgcacctgc ccctcggggtacacagggccagcctgcagccaggacgtggatgagtgtgctctgggtgcc aacccttgtgagcacgcaggcaaatgcctcaacacactgggttcttttgagtgccagtgt ctacagggctacacgggaccccgctgtgagattgatgttaatgagtgcatctccaaccca tgtcagaatgatgccacttgcctggaccagattggggagttccaatgcatatgtatgcca ggttatgaaggtgtatactgtgaaatcaacacggatgagtgcgccagcagcccctgtctg cacaatggccactgcatggacaagatcaatgagttccaatgtcagtgccccaaaggcttc aacgggcacctgtgccagtatgatgtggatgagtgtgccagcacaccatgcaagaacggt gccaagtgcctggatgggcccaacacctatacctgcgtgtgtacagaaggttacacaggg acccactgcgaagtggacattgacgagtgtgaccctgacccctgccactatggttcctgt aaggatggtgtggccacctttacctgcctgtgccagccaggctacacaggccatcactgt gagaccaacatcaatgagtgccacagccaaccgtgccgccatgggggcacctgccaggac cgtgacaactcctacctctgcttatgcctcaagggaaccacagggcccaactgtgagatc aacctggatgactgcgccagcaacccctgtgactctggcacctgtctggacaagattgat ggctacgaatgtgcctgtgaaccaggctacacaggaagcatgtgtaacgtcaacattgac gaatgtgcgggcagcccctgccacaacgggggcacttgtgaggatggcatcgcgggcttc acttgccgctgccccgagggctaccatgaccccacgtgcctgtccgaggtcaacgagtgc aacagtaacccctgcatccacggagcttgccgggatggcctcaatgggtacaagtgtgac tgtgcccctgggtggagtggaacaaactgtgacatcaacaacaacgagtgtgagtccaac ccttgtgtcaacggtggcacctgcaaggacatgaccagtggctacgtatgcacctgccga gaaggcttcagtggccctaattgccagaccaacatcaacgaatgtgcctccaacccctgc ctgaaccaggggacctgcattgatgatgtcgctggatacaagtgcaactgtcctctgcca tatacaggagccacgtgtgaggtggtgttggccccatgtgctaccagcccctgcaaaaac agcggggtatgcaaggagtctgaagactatgagagtttttcctgtgtctgtcccacaggc tggcaaggtcaaacctgcgaggttgacatcaatgagtgtgtgaaaagcccatgtcgccat ggggcctcctgccagaacaccaatggcagctaccgctgcctctgccaggccggctataca ggtcgcaactgtgagagtgacatcgatgactgccgccccaacccgtgtcacaatgggggt tcctgcaccgatggcatcaacacagccttctgcgactgcctgcccggcttccagggtgcc ttctgtgaggaggacatcaatgaatgtgccagcaatccctgccaaaatggtgccaattgc actgactgtgtggacagctacacatgtacctgccccgtgggcttcaatggcatccactgc gagaacaacacacctgactgtactgagagctcctgcttcaatggtggtacctgtgtggat ggtatcaactccttcacctgtctgtgtccacctggcttcacgggcagctactgtcagtat gatgtcaatgagtgtgattcacggccctgtctgcacggtggtacctgccaagacagctat ggtacttataagtgtacctgcccacagggctacactggtctcaactgccagaaccttgtg cgctggtgcgactcggctccctgcaagaatggtggcaggtgctggcagaccaacacgcag taccactgtgagtgccgcagcggctggactggcgtcaactgcgacgtgctcagtgtgtcc tgtgaggtggctgcacagaagcgaggcattgacgtcactctcctgtgccagcatggaggg ctctgtgtggatgagggagataaacattactgccactgccaggcaggctacacgggcagc tactgtgaggacgaggtggacgagtgctcacctaacccctgccagaatggagctacctgc actgactatctcggcggcttttcctgcaagtgtgtggctggctaccatgggtctaactgc tccgaggagatcaacgagtgcctgtcccagccctgccagaatgggggtacctgcattgat ctgaccaactcctacaagtgttcctgcccccgggggacacagggtgtacactgtgagatc aatgttgatgactgccatcccccccttgaccctgcctcccgaagccccaagtgcttcaac aatggcacctgtgtggaccaggtgggtggctatacctgcacctgcccaccaggcttcgtc ggggagcggtgtgagggtgatgtcaatgaatgtctctccaacccctgtgacccacgtggc acccagaactgtgtgcagcgtgttaatgacttccactgcgagtgccgggctggccacact ggacgccgctgtgagtcagtcatcaatggctgcaggggcaaaccttgcaagaatgggggt gtctgtgccgtggcctccaacaccgcccgtggattcatctgtaggtgccctgcgggcttc gagggtgccacatgtgagaatgatgcccgcacttgtggcagcttacgctgcctcaacggt ggtacatgcatctcgggcccacgtagtcccacctgcctatgcctgggatccttcaccggc cctgagtgccagttcccagccagcagcccctgtgtgggtagcaacccctgctacaatcag ggcacctgtgagcccacatccgagaaccctttctaccgctgtctatgccctgccaaattc aacgggctactgtgccacatcctggactacagcttcacaggtggcgctgggcgcgacatt cccccaccgcagattgaggaggcctgtgagctgcctgagtgccaggtggatgcaggcaat aaggtctgcaacctgcagtgtaataatcacgcatgtggctgggatggtggcgactgctcc ctcaacttcaatgacccctggaagaactgcacgcagtctctacagtgctggaagtatttt agcgacggccactgtgacagccagtgcaactcggccggctgcctctttgatggcttcgac tgccagctcaccgagggacagtgcaaccccctgtatgaccagtactgcaaggaccacttc agtgatggccactgcgaccagggctgtaacagtgccgaatgtgagtgggatggcctagac tgtgctgagcatgtacccgagcggctggcagccggcaccctggtgctggtggtgctgctt ccacccgaccagctacggaacaactccttccactttctgcgggagctcagccacgtgctg cacaccaacgtggtcttcaagcgtgatgcgcaaggccagcagatgatcttcccgtactat ggccacgaggaagagctgcgcaagcacccaatcaagcgctctacagtgggttgggccacc tcttcactgcttcctggtaccagtggtgggcgccagcgcagggagctggaccccatggac atccgtggctccattgtctacctggagatcgacaaccggcaatgtgtgcagtcatcctcg cagtgcttccagagtgccaccgatgtggctgccttcctaggtgctcttgcgtcacttggc agcctcaatattccttacaagattgaggccgtgaagagtgagccggtggagcctccgctg ccctcgcagctgcacctcatgtacgtggcagcggccgccttcgtgctcctgttctttgtg ggctgtggggtgctgctgtcccgcaagcgccggcggcagcatggccagctctggttccct gagggtttcaaagtgtcagaggccagcaagaagaagcggagagagcccctcggcgaggac tcagtcggcctcaagcccctgaagaatgcctcagatggtgctctgatggacgacaatcag aacgagtggggagacgaagacctggagaccaagaagttccggtttgaggagccagtagtt ctccctgacctgagtgatcagactgaccacaggcagtggacccagcagcacctggacgct gctgacctgcgcatgtctgccatggccccaacaccgcctcagggggaggtggatgctgac tgcatggatgtcaatgttcgaggaccagatggcttcacacccctcatgattgcctcctgc agtggagggggccttgagacaggcaacagtgaagaagaagaagatgcacctgctgtcatc tctgacttcatctaccagggcgccagcttgcacaaccagacagaccgcaccggggagacc gccttgcacttggctgcccgatactctcgttcagatgctgcaaagcgcttgctggaggcc agtgcagatgccaacatccaggacaacatgggccgtactccgttacatgcagcagtttct gcagatgctcagggtgtcttccagatcctgctccggaacagggccacagatctggatgcc cgaatgcatgatggcacaactccactgatcctggctgcgcgcctggccgtggagggcatg ctggaggacctcatcaactcacatgctgacgtcaatgccgtggatgacctaggcaagtcg gctttgcattgggcggccgcggtgaacaatgtggatgctgctgttgtgctcctgaagaac ggagccaacaaggacatgcagaacaacaaggaggagactcccctgttcctggccgcccgt gagggcagctatgagactgccaaagtgttgctggaccactttgccaaccgggacatcacg gatcacatggaccgattgccgcgggacatcgcacaggagcgtatgcaccacgatatcgtg cggcttttggatgagtacaacctggtgcgcagcccacagctgcatggcactgccctgggt ggcacacccactctgtctcccacactctgctcgcccaatggctacctgggcaatctcaag tctgccacacagggcaagaaggcccgcaagcccagcaccaaagggctggcttgtggtagc aaggaagctaaggacctcaaggcacggaggaagaagtcccaggatggcaagggctgcctg ttggacagctcgagcatgctgtcgcctgtggactccctcgagtcaccccatggctacttg tcagatgtggcctcgccacccctcctcccctccccattccagcagtctccatccatgcct ctcagccacctgcctggtatgcctgacactcacctgggcatcagccacttgaatgtggca gccaagcctgagatggcagcactggctggaggtagccggttggcctttgagccacccccg ccacgcctctcccacctgcctgtagcctccagtgccagcacagtgctgagtaccaatggc acgggggctatgaatttcaccgtgggtgcaccggcaagcttgaatggccagtgtgagtgg cttccccggctccagaatggcatggtgcccagccagtacaacccactacggccgggtgtg acgccgggcacactgagcacacaggcagctggcctccagcatagcatgatggggccacta cacagcagcctctccaccaataccttgtccccgattatttaccagggcctgcccaacaca cggctggcaacacagcctcacctggtgcagacccagcaggtgcagccacagaacttacag ctccagcctcagaacctgcagccaccatcacagccacacctcagtgtgagctcggcagcc aatgggcacctgggccggagcttcttgagtggggagcccagtcaggcagatgtacaaccg ctgggccccagcagtctgcctgtgcacaccattctgccccaggaaagccaggccctgccc acatcactgccatcctccatggtcccacccatgaccactacccagttcctgacccctcct tcccagcacagttactcctcctcccctgtggacaacacccccagccaccagctgcaggtg ccagagcaccccttcctcaccccatcccctgagtcccctgaccagtggtccagctcctcc ccgcattccaacatctctgattggtccgagggcatctccagcccgcccaccaccatgccg tcccagatcacccacattccagaggcatttaaataa

Mus musculus (house mouse): 18129 Help Entry 18129             CDS       T01002                                  Symbol Notch2, N2 Name (RefSeq) notch 2   KO K20994   Notch 2 Organism mmu  Mus musculus (house mouse) Pathway mmu01522   Endocrine resistance mmu04330   Notch signaling pathway mmu04658   Th1 and Th2 cell differentiation mmu04919   Thyroid hormone signaling pathway mmu05165   Human papillomavirus infection mmu05200   Pathways in cancer mmu05206   MicroRNAs in cancer mmu05207   Chemical carcinogenesis - receptor activation mmu05224   Breast cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     18129 (Notch2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     18129 (Notch2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     18129 (Notch2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     18129 (Notch2)    05206 MicroRNAs in cancer     18129 (Notch2)    05207 Chemical carcinogenesis - receptor activation     18129 (Notch2)   09162 Cancer: specific types    05224 Breast cancer     18129 (Notch2)   09172 Infectious disease: viral    05165 Human papillomavirus infection     18129 (Notch2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     18129 (Notch2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank Notch NOD NODP Ank_5 Ank_3 Ank_4 EGF_3 EGF_Teneurin FXa_inhibition EGF_DL_JAG F13C5_C cEGF Motif Other DBs NCBI-GeneID:  18129 NCBI-ProteinID:  NP_035058 MGI:  97364 Ensembl:  ENSMUSG00000027878 UniProt:  O35516 LinkDB All DBs Position 3:97920854..98057683 Genome browser AA seq 2473 aa AA seqDB search MPALRPAALRALLWLWLCGAGPAHALQCRGGQEPCVNEGTCVTYHNGTGFCRCPEGFLGE YCQHRDPCEKNRCQNGGTCVPQGMLGKATCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGT CHMLSRDTYECTCQVGFTGKQCQWTDACLSHPCENGSTCTSVASQFSCKCPAGLTGQKCE ADINECDIPGRCQHGGTCLNLPGSYRCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTG DFTFECNCLPGFEGSTCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD ECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAYASCTPGSTCIDRVASF SCLCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC LCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP CLNGAKCIDHPNGYECQCATGFTGILCDENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGLNCEINFDDCASNPCMHGVCV DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCICPEGPHHPSCYSQ VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGVNCEVDKNECLSNPCQNGGTCNNLVNGYR CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDVSGYTCHCMLPYTGKNCQTVLAPCSPN PCENAAVCKEAPNFESFSCLCAPGWQGKRCTVDVDECISKPCMNNGVCHNTQGSYVCECP PGFSGMDCEEDINDCLANPCQNGGSCVDHVNTFSCQCHPGFIGDKCQTDMNECLSEPCKN GGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPVGFTGP FCLHDINECSSNPCLNAGTCVDGLGTYRCICPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ EKARPHCLCPPGWDGAYCDVLNVSCKAAALQKGVPVEHLCQHSGICINAGNTHHCQCPLG YTGSYCEEQLDECASNPCQHGATCNDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG TCIDLVNHFKCSCPPGTRGLLCEENIDECAGGPHCLNGGQCVDRIGGYTCRCLPGFAGER CEGDINECLSNPCSSEGSLDCVQLKNNYNCICRSAFTGRHCETFLDVCPQKPCLNGGTCA VASNMPDGFICRCPPGFSGARCQSSCGQVKCRRGEQCIHTDSGPRCFCLNPKDCESGCAS NPCQHGGTCYPQRQPPHYSCRCPPSFGGSHCELYTAPTSTPPATCQSQYCADKARDGICD EACNSHACQWDGGDCSLTMEDPWANCTSTLRCWEYINNQCDEQCNTAECLFDNFECQRNS KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCASDQPENLAEGTLIIVVLLPPEQLLQ DSRSFLRALGTLLHTNLRIKQDSQGALMVYPYFGEKSAAMKKQKMTRRSLPEEQEQEQEV IGSKIFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSVFSELESPRNAQL LYLLAVAVVIILFFILLGVIMAKRKRKHGFLWLPEGFTLRRDSSNHKRREPVGQDAVGLK NLSVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEDDPIDRRPWTQQHLEAADI RHTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANII TDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVA ADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKS ALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDIT DHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVLCGPNRSFLSLKHTPM GKKARRPNTKSTMPTSLPNLAKEAKDAKGSRRKKCLNEKVQLSESSVTLSPVDSLESPHT YVSDATSSPMITSPGILQASPTPLLAAAAPAAPVHTQHALSFSNLHDMQPLAPGASTVLP SVSQLLSHHHIAPPGSSSAGSLGRLHPVPVPADWMNRVEMNETQYSEMFGMVLAPAEGAH PGIAAPQSRPPEGKHMSTQREPLPPIVTFQLIPKGSIAQAAGAPQTQSSCPPAVAGPLPS MYQIPEMPRLPSVAFPPTMMPQQEGQVAQTIVPTYHPFPASVGKYPTPPSQHSYASSNAA ERTPSHGGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGGGGGQRGPGTH MSEPPHSNMQVYA NT seq 7422 nt NT seq  +upstreamnt  +downstreamnt atgcccgctctgcgtcccgccgcgctgcgggcgctgctgtggctctggctgtgcggcgcg ggccccgcgcacgctttgcagtgtcgaggtggtcaagagccctgtgtaaatgaagggacc tgtgttacctaccacaacggcacaggcttctgccgatgtccagagggcttcttgggagaa tattgccaacatcgagacccctgtgagaaaaaccgctgtcagaatggtggtacttgtgtg ccgcagggcatgttggggaaagctacctgccgatgtgctccaggattcacaggagaggac tgccaatactccacctctcacccctgctttgtgtcccgcccttgtcagaatgggggtacc tgtcacatgctcagccgggacacctacgagtgcacctgccaagtcggcttcacagggaag cagtgtcagtggacagatgcctgtctatctcatccctgcgaaaatggaagcacctgtaca tctgtggccagccagttctcctgcaaatgccctgcaggcctcacagggcagaagtgtgaa gctgatatcaatgagtgtgacattccaggacgctgccaacatggtggcacctgcctcaac cttcctggttcctacagatgccaatgtcctcagggcttcacaggccagcactgtgacagc ccttatgtgccctgtgcaccctcgccctgcgtcaacggaggcacctgtcgtcagactggc gacttcactttcgaatgcaactgcctgccaggttttgaagggagcacctgtgagcggaat atcgacgactgccccaaccacaagtgtcagaatggaggagtttgtgtggatggtgtcaat acctacaattgccgctgtccccctcagtggactgggcagttctgcacagaagatgtggac gagtgtctgttgcagcccaacgcttgtcagaatggaggcacctgcaccaaccgaaacgga ggctatggctgcgtgtgtgtgaacggctggagcggagatgactgcagcgagaatatcgat gactgtgcctatgcttcctgcacgccagggtccacctgcattgaccgcgtggcctccttc tcctgcctgtgtccggagggaaaggcgggtctcctgtgccatctggatgatgcctgtatc agcaacccttgtcacaagggggcgctgtgtgacaccaaccccctgaacgggcagtacatt tgcacctgcccacagggctacaagggcgctgactgcacagaagacgtggatgagtgtgct atggccaacagtaacccttgtgagcatgcaggaaagtgtgtgaatacagatggcgccttc cactgtgagtgtctgaagggctacgcagggcctcgctgtgagatggacatcaacgagtgt cattcagacccctgccagaacgacgccacctgcctggataagatcggaggcttcacctgt ctgtgcatgccaggtttcaaaggtgtgcattgtgagctggaggtaaatgaatgccagagc aacccgtgtgtgaacaacgggcagtgtgtggacaaagtcaaccgcttccagtgtctgtgt ccccctggcttcacaggaccagtgtgccagatcgacattgatgactgctccagtactccc tgcctgaatggggccaagtgcatcgatcacccgaatggctatgaatgccagtgtgccaca ggtttcactggcatattgtgtgatgagaacatcgacaactgtgacccagatccttgccac catggccagtgccaggatgggatcgactcctacacctgcatctgcaaccctgggtacatg ggagccatctgtagtgaccagattgatgaatgctacagcagcccttgcttgaacgatggg cgctgcattgacctggtgaatggttaccagtgcaactgccaaccaggcacatcaggcctt aattgtgaaattaattttgatgactgtgccagcaacccttgtatgcacggagtctgtgtg gacggcatcaatcgctacagctgtgtgtgctctccgggattcacaggccagaggtgcaat attgacattgatgagtgtgcctccaacccctgtcgcaagggtgcgacgtgcatcaatgat gtgaatggtttccggtgtatatgccccgagggaccgcatcatcctagctgctactcacag gtgaacgagtgcctgagcaatccctgcatccacggaaactgtactggaggtctcagtggc tataagtgcctctgcgatgcaggctgggttggtgtcaactgtgaggtggacaaaaatgag tgtctttctaacccatgccagaatggaggaacgtgcaataacctggtgaatggctacagg tgtacctgcaagaaggggttcaaaggctacaactgccaggtgaatatagatgagtgtgcc tccaacccgtgtctgaaccaaggaacctgctttgatgacgtcagtggctacacttgccac tgcatgttgccttacacaggcaagaactgtcaaacagtgttggctccctgttccccaaac ccgtgtgagaatgctgctgtttgtaaagaggcacccaattttgagagcttcagctgcttg tgtgctcctggctggcaaggtaaacgatgtacagttgacgttgatgagtgtatctccaag ccgtgtatgaacaatggtgtctgccacaacactcagggcagctacgtgtgtgagtgtcct cccggcttcagtgggatggactgtgaagaggacatcaatgattgccttgccaacccctgc cagaacggaggctcctgtgtggaccatgtgaataccttctcctgccagtgccatcctggc ttcataggggacaagtgccagacagacatgaatgagtgtctgagcgagccctgtaagaat ggggggacctgctccgactatgtcaacagttacacctgcacatgccctgcgggcttccac ggagtccactgtgaaaacaacattgacgagtgcactgagagctcctgcttcaatggcggc acgtgtgttgatggaatcaactctttctcttgcttgtgccccgtgggtttcactggtccc ttctgcctccatgatatcaatgagtgcagctctaacccgtgcctgaatgctggaacgtgt gttgatggtctgggtacctaccgatgcatctgtcccttgggctacaccgggaaaaactgt cagaccctggtgaacctctgcagccggtctccgtgtaaaaacaaaggaacttgtgttcag gaaaaggcaaggccccactgtctgtgtccgcctggatgggatggtgcatactgtgatgtg ctcaacgtgtcctgtaaggcggcagccttgcagaaaggagtacctgttgaacacttgtgc cagcactcgggcatctgtatcaatgctggcaacacccatcactgccagtgccccctgggc tacacggggagctactgcgaggagcagcttgatgagtgtgcatccaatccatgccagcac ggtgccacctgcaatgacttcatcggaggatacagatgtgagtgtgttccaggatatcag ggtgtcaactgtgagtatgaagtggacgagtgccagaaccaaccctgccagaatggaggc acctgcatcgaccttgtgaaccatttcaagtgttcgtgtcccccaggcacccggggcctg ctgtgtgaagagaacatcgatgaatgtgctgggggcccccactgccttaacggtggccag tgcgtggaccggattggaggctacacttgtcgctgtttgcctggctttgctggggagcgg tgtgagggggacatcaacgaatgcctgtccaacccttgcagctcagagggcagcctggac tgcgttcagctcaaaaataactacaactgtatctgccgcagcgccttcacgggccggcac tgtgaaaccttcctagatgtgtgtccccagaagccttgcctgaacggagggacttgtgcc gtggctagcaacatgcccgatggcttcatctgtcgttgtcccccagggttctctggggcg agatgccagagcagctgtggacaagtgaagtgcaggagaggggagcagtgtatccacact gactcgggacctcgctgcttctgcctgaaccccaaggactgcgagtcaggatgtgccagt aacccctgccagcatgggggcacctgctatcctcagcgccagcctcctcactattcctgc cgctgccctccgtcgttcgggggcagccactgcgaactctacacagcccccaccagcacc cctcctgctacctgtcagagtcagtactgcgccgacaaggctcgggatggcatctgtgac gaggcctgcaatagtcatgcctgccagtgggatggaggtgactgttccctcactatggag gacccctgggccaactgcacctccactcttcgctgctgggaatacatcaacaaccagtgt gatgagcagtgcaacaccgcagagtgcctgtttgacaactttgagtgccagaggaatagc aagacgtgcaagtatgacaaatactgtgcagaccacttcaaagacaaccactgtgatcag ggatgcaacagcgaggagtgtggctgggatgggctggactgcgcttcggaccagcctgag aacctggcagagggcaccctgatcatcgtggtgctcctgccccctgaacagctgctgcag gattcgcgaagcttcttgagggccctgggcaccctgctccacaccaacttgcgcattaaa caagattctcagggcgctctcatggtgtacccctactttggggagaagtcagctgccatg aagaagcagaagatgacacgcaggtctcttcctgaggagcaggagcaggagcaggaggtg ataggctctaagatatttctggagatcgacaaccgacagtgtgttcaagattcagaccag tgcttcaaaaacacagatgcggcagctgctctcctggcttctcatgccatccaagggacc ctatcctaccctctagtgtctgttttcagtgaactggagagtccaagaaacgcccagctt ctctatctgctcgcggtcgctgttgtcatcatcctgttcttcatcctgctgggggtcatc atggccaagcggaagcgcaagcatggcttcctctggctgccggaagggttcaccctccgc cgagactctagcaatcacaagcgccgtgaacctgtgggacaggatgccgtggggctgaaa aatctctccgtgcaagtgtcagaggctaacctgattggttctgggacaagtgaacattgg gttgatgatgaaggaccccagccaaagaaagccaaggctgaggatgaggctttgctgtcg gaagatgaccccatcgatcgacggccctggacacagcagcaccttgaagctgcagacatc cgccacactccatccctggcactcactcctcctcaggcagaacaggaggtggacgtgctg gacgtgaatgtccgaggcccagatgggtgtactccactgatgctggcttctctccgagga ggcagctcagacctgagtgatgaagacgaagatgctgaggactcttctgccaacatcatc acagacttggtctaccaaggtgccagccttcaagcacagacagaccgcactggcgagatg gccctgcaccttgcagcccgctattcgagagctgatgctgccaaacgcctcctggatgct ggtgcggatgcaaatgcccaggacaacatgggccgatgtcctcttcacgctgcggtggca gcagacgcccaaggtgtctttcagattctgatccgcaaccgtgtaaccgatctggatgcc agaatgaacgatggtactacccccctgatcctggctgcccgcctggctgtggaaggaatg gtggcagagttgatcaattgccaagcagatgtcaatgcagtggatgaccatggaaaatct gccctccactgggcagctgctgtcaataatgtggaggcgactcttctgctgttgaagaat ggggccaacagagatatgcaggacaataaggaagagacacctttgtttcttgctgcccga gagggaagttatgaagcggccaaaatcctgttagaccattttgccaaccgggacatcact gaccacatggaccgccttccccgggatgtggctcgggaccgcatgcaccatgacatcgtt cgcctcctggacgagtataacgtgactcccagccctccgggaacggtcttgacttctgcg ctctcacctgtcctctgtgggcccaacaggtctttcctcagtctgaagcacaccccaatg ggtaagaaggctaggcggcccaacaccaagagcaccatgcccacgagcctgcctaacctt gccaaggaggccaaggatgccaagggcagcaggaggaagaagtgtctgaacgagaaggtc cagctgtccgagagctcagtgactctatcccccgtcgattcgctcgagtctcctcacacg tatgtctccgatgccacatcctctcccatgatcacatcccctggaatcttacaggcctcg cccacccccctgctggctgctgccgccccggctgccccagtgcacacacagcatgcgctg tctttctctaaccttcatgacatgcagcctttggctcctggagccagcaccgtgctcccc tcggtcagccagctgctatcccaccaccacatcgcgcccccaggtagtagcagtgcagga agcttgggcaggttacatccagttcctgtcccagcagactggatgaaccgtgtggagatg aacgagacccagtacagtgaaatgtttggcatggtcctggctcctgcagagggagcccac cctggcatagcagctccccagagcagacctccggaagggaagcacatgtccacccagcgg gagcccttgcctcccatcgtgactttccagcttatcccaaaaggcagcattgcccaggca gccggagctccccagacgcagtccagttgccctccagctgttgcaggccccttgccctct atgtaccagatcccagagatgccccgtttgcccagtgtggctttcccacctaccatgatg ccccagcaggaggggcaggtagctcagaccattgtgccaacctatcatcctttcccagcc tctgtgggcaagtaccccacacccccttcccaacacagttacgcctcctcaaatgctgct gagcgaacccccagtcatggtggtcacctccagggcgagcacccatacctgacaccatcc ccagagtctcctgaccaatggtcaagctcttcaccacactctgcatctgactggtcagat gtgaccaccagcccaactcctggaggtggtggaggcggtcagcggggacccggaacacac atgtccgagccaccacacagcaacatgcaggtgtatgcatga

Mus musculus (house mouse): 18131 Help Entry 18131             CDS       T01002                                  Symbol Notch3, N3, hpbk Name (RefSeq) notch 3   KO K20995   Notch 3 Organism mmu  Mus musculus (house mouse) Pathway mmu01522   Endocrine resistance mmu04330   Notch signaling pathway mmu04371   Apelin signaling pathway mmu04658   Th1 and Th2 cell differentiation mmu04919   Thyroid hormone signaling pathway mmu05165   Human papillomavirus infection mmu05200   Pathways in cancer mmu05206   MicroRNAs in cancer mmu05224   Breast cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     18131 (Notch3)    04371 Apelin signaling pathway     18131 (Notch3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     18131 (Notch3)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     18131 (Notch3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     18131 (Notch3)    05206 MicroRNAs in cancer     18131 (Notch3)   09162 Cancer: specific types    05224 Breast cancer     18131 (Notch3)   09172 Infectious disease: viral    05165 Human papillomavirus infection     18131 (Notch3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     18131 (Notch3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  EGF hEGF EGF_TEN EGF_CA Ank_2 Ank Notch EGF_2 NODP Ank_4 NOD Ank_3 Ank_5 EGF_Teneurin EGF_3 cEGF JAG1-like_EGF2 EGF_DL_JAG Gurken_M Motif Other DBs NCBI-GeneID:  18131 NCBI-ProteinID:  NP_032742 MGI:  99460 Ensembl:  ENSMUSG00000038146 UniProt:  Q61982 LinkDB All DBs Position 17:complement(32339794..32385869) Genome browser AA seq 2318 aa AA seqDB search MGLGARGRRRRRRLMALPPPPPPMRALPLLLLLAGLGAAAPPCLDGSPCANGGRCTHQQP SLEAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCLRGFQGPDCSQ PDPCVSRPCVHGAPCSVGPDGRFACACPPGYQGQSCQSDIDECRSGTTCRHGGTCLNTPG SFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDD CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGGHS CVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNP CHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC GRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCV NGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEG TLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLD LVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEIN ECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCSHGVCHDAPGGFRCV CEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPCTPSL CEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFRCICHR GYTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPG TCTDHVASFTCACPPGYGGFHCEIDLPDCSPSSCFNGGTCVDGVSSFSCLCRPGYTGTHC QYEADPCFSRPCLHGGICNPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNGGRCVQTG AYCICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKCIDKGRSHYCVCPEGRTGS HCEHEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQPCQNGGSCID LVARYLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTG LHCEADINECRPGACHAAHTRDCLQDPGGHFRCVCHPGFTGPRCQIALSPCESQPCQHGG QCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVGIPCQQTARGPRCACPPGL SGPSCRVSRASPSGATNASCASAPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSAAP EVPEEPRCPRAACQAKRGDQNCDRECNTPGCGWDGGDCSLNVDDPWRQCEALQCWRLFNN SRCDPACSSPACLYDNFDCYSGGRDRTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLD CASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDARGQAMVFPYH RPSPGSESRVRRELGPEVIGSVVMLEIDNRLCLQSAENDHCFPDAQSAADYLGALSAVER LDFPYPLRDVRGEPLEAPEQSVPLLPLLVAGAVFLLIIFILGVMVARRKREHSTLWFPEG FALHKDIAAGHKGRREPVGQDALGMKNMAKGESLMGEVVTDLNDSECPEAKRLKVEEPGM GAEEPEDCRQWTQHHLVAADIRVAPATALTPPQGDADADGVDVNVRGPDGFTPLMLASFC GGALEPMPAEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLL DAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVE GMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLA AREGSYEAAKLLLDHLANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPSGPHGL GPLLCPPGAFLPGLKAVQSGTKKSRRPPGKTGLGPQGTRGRGKKLTLACPGPLADSSVTL SPVDSLDSPRPFSGPPASPGGFPLEGPYATTATAVSLAQLGASRAGPLGRQPPGGCVLSF GLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGAPVSPQERPPPYLAAPGHGEE YPAAGTRSSPTKARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSDSTPSPATATNAT ASGALPAQPHPISVPSLPQSQTQLGPQPEVTPKRQVMA NT seq 6957 nt NT seq  +upstreamnt  +downstreamnt atggggctgggggcccggggccgccgccgccgtcgtcgcctgatggccttgccaccgcca ccaccgcccatgcgggcgctgcccctgctgctgctgctagcggggctgggggctgcagca cccccttgtctggatggaagcccatgtgcaaatggaggtcggtgcacccaccagcagccc tccctggaggctgcttgcctgtgcctgccaggctgggtgggtgagcggtgccagctggaa gacccttgccactcaggcccttgtgctggccgaggcgtttgccagagttcagtggtggcg ggcaccgcccgattctcctgtcgttgtctccgtggcttccaaggcccagactgctcccag ccagacccctgcgtcagcaggccctgtgttcatggtgccccctgctcagtggggccggat ggccgatttgcctgtgcctgcccacctggctaccagggtcaaagctgccaaagtgacata gatgagtgccgatctggtacaacttgccgtcatggtggtacctgtctcaatacacctgga tccttccgctgccagtgtcctcttggttatacagggctgctgtgtgagaaccccgtagtg ccctgtgccccttccccgtgtcgtaatggtggcacctgtaggcagagcagtgatgtcaca tatgactgtgcttgccttcctggcttcgagggccagaactgtgaagtcaacgtggatgac tgtcctggacatcggtgtctcaatgggggaacgtgtgtagacggtgtcaatacttacaac tgccagtgccctccggagtggacaggccagttctgtacagaagatgtggatgagtgtcag ctgcagcccaatgcctgccacaatgggggtacctgcttcaacctactgggtggccacagc tgtgtatgtgtcaatggctggacgggtgagagctgcagtcagaatatcgatgactgtgct acagccgtgtgtttccatggggccacctgccatgaccgtgtggcctctttctactgtgcc tgccctatggggaagacaggcctcttgtgtcatctggatgatgcatgtgtcagcaacccc tgccatgaggatgctatctgtgacacaaaccctgtgagtggccgggccatctgcacctgc ccacctggcttcactggaggggcatgtgaccaggatgtggatgagtgctcgattggtgcc aacccctgtgaacatttgggtcggtgtgtgaatacacagggctcattcttgtgccaatgt ggccgtggctatactggacctcgctgtgagactgatgtcaatgagtgtctctccgggccc tgccgcaaccaggccacgtgtcttgaccgaattggccagtttacttgcatctgcatggca ggcttcacagggacctactgtgaggtggacatcgacgaatgtcagagcagcccatgtgtc aatggtggtgtctgcaaggacagagtcaatggcttcagctgcacctgcccatcaggattc agtgggtccatgtgtcagctggatgtggatgagtgtgcaagcactccctgccggaatggt gccaagtgtgtggaccagcctgacggctatgagtgtcgctgtgcagagggctttgagggc actttgtgtgagcgaaacgtggatgactgctctccggatccctgccaccacgggcgctgt gtcgatggcattgctagcttctcgtgtgcttgtgccccaggctatacgggcatacgctgt gagagccaggtggatgagtgccgcagccagccctgtcgatatgggggcaaatgtctagac ttggtggacaagtacctctgccgttgtcctcccggaaccacaggtgtgaactgtgaagtc aacattgatgactgtgccagtaacccctgtacctttggagtttgccgtgatggcatcaac cgttatgactgtgtctgtcagcctggattcacagggcccctctgcaacgtggagatcaat gagtgtgcatccagcccatgtggagagggtggctcctgtgtggatggggaaaatggcttc cactgcctctgtccacctggctccctgcctccactttgcctacctgcgaaccatccctgt gcccacaagccctgtagtcatggagtctgccatgatgcaccaggcgggttccgctgtgtt tgtgagcccgggtggagtggccctcgctgtagccagagcctggctccagatgcctgtgag tcccagccctgccaggctggtggcacctgcaccagtgatggaataggctttcgctgcacc tgtgcccctggattccagggccatcagtgtgaggtgctgtccccctgtactccaagcctc tgtgagcacggaggccactgtgagtctgaccctgaccggctgactgtctgttcctgtccc ccaggctggcaaggcccacgatgccagcaggatgtggatgaatgtgccggtgcctcaccc tgcggcccccatggtacctgcaccaacctgccagggaatttcaggtgcatctgccacagg ggatacactggccccttctgtgatcaagacattgacgactgtgaccccaacccgtgcctc catggtggctcctgccaggatggcgtgggctccttttcctgttcttgcctcgacggcttt gctggtcctcgctgtgcccgagatgtggacgaatgtctgagcagcccctgtggccctggc acctgtactgatcacgtggcctccttcacctgtgcctgtccacctggttatggaggcttc cactgtgagattgacttgccggactgcagccccagttcctgcttcaatggagggacctgt gtggatggcgtgagctccttcagctgtctgtgtcgccccggctacacaggcacacactgc caatacgaggctgacccctgcttttcccggccctgtctgcacgggggcatctgcaacccc acccacccaggatttgaatgcacctgccgggagggcttcactgggagtcagtgtcagaac ccagtggactggtgcagccaggcaccctgtcagaatgggggtcgctgtgtccagactggg gcttactgcatttgtccacctggatggagtggccgcctgtgcgacatacaaagcctgccc tgcacggaggccgcagcccagatgggggtgaggttggagcagctgtgtcaggaaggtgga aagtgcatagacaagggccgctcccactactgtgtgtgtccagagggccgtacgggtagt cactgtgaacacgaggtggatccctgcacggcccagccttgccagcacgggggcacttgc cgtggttacatggggggctatgtgtgtgagtgtccagctggctatgctggtgacagttgt gaggataatatagatgagtgtgcttcccagccctgccagaacggaggctcctgtatcgat cttgtggcccgctatctctgttcctgtccccctggcacactgggagttctctgtgagatc aatgaggacgactgtgacctaggcccatccttggactcaggcgttcagtgcctacacaat ggcacctgtgtggacctggtgggtggcttccgctgtaactgtcccccaggatacacaggt ctgcactgtgaggcagacatcaatgagtgtcgcccgggtgcctgccatgcagcgcatact cgggactgcctacaagatccaggtgggcatttccgctgcgtctgccatcctggcttcaca gggcctcgctgtcagattgctctgtccccctgtgagtcccagccatgtcagcatggaggc cagtgccgtcacagcctaggccgtggaggtgggctgaccttcacctgtcactgtgtcccg ccattctggggtctgcgttgtgagcgggtggcacgctcttgccgagagctgcagtgccca gtgggtatcccatgccagcagacagcccgtggaccacgctgcgcttgtcctccggggctg tccgggccctcctgccgggtttctagggcgtcaccctcaggagctactaacgccagctgc gcctctgccccttgtctgcatgggggctcatgcctacctgtacagagtgtccctttcttc cgctgtgtgtgcgctccgggctggggcggcccgcgttgtgagaccccttccgcagcccct gaggtccccgaggagccacggtgcccgcgagcggcttgccaggccaagcgaggggaccag aactgcgatcgtgagtgcaacaccccaggctgtggctgggatggcggtgactgctcactg aacgtggacgacccctggaggcagtgtgaggcactgcagtgctggcgtctcttcaacaac agccggtgtgacccggcctgcagctctccagcctgcctctatgacaactttgactgctac tctggtggccgcgaccgcacctgcaaccctgtttatgagaagtactgcgccgaccacttt gcagatggccgttgtgaccagggctgcaacactgaggaatgcggctgggatgggctggac tgtgccagcgaggtcccggcccttttggcccgaggggttctggtcctcacagttcttctg cctcctgaagagttgctgcgctccagtgccgactttctgcagcgactcagcgctattctg cgcacctcactgcgcttccgcttggacgcacgtggccaggccatggtcttcccctatcac cggccaagccctggctctgaatcccgggtccgtcgtgagctgggtcctgaggtgatcggc tctgtggtgatgctggagattgacaaccggctctgtctgcagtcagctgagaatgaccac tgcttccctgatgcccagagtgctgctgactacctgggagccttgtcagcagtggagcga cttgatttcccatacccacttcgggatgtgcgaggagagccgctggaggccccagagcag agcgtgccactgctgccactgctggtggcaggggctgtctttctactcatcatcttcatc ctgggtgtcatggttgccaggcgaaagcgagaacacagcaccctctggttccctgagggt tttgcattacacaaggacatagctgctggccacaagggccggagggagcctgtgggacaa gatgcactgggaatgaagaacatggccaagggtgagagtctgatgggggaggtggtcaca gacttgaatgactcagaatgtccagaggccaagagactgaaggtagaggagccgggcatg ggtgcagaggagcctgaggactgtcgccagtggacccaacaccacctggttgctgctgat atccgtgtggcaccagccacagcgctgactcctcctcagggagatgcagatgcagacgga gtggatgtcaacgtccgagggcctgatggcttcaccccacttatgctggcctccttctgt gggggagccctggagccgatgccagctgaggaggatgaggcggatgacacatcagccagc attatctcagatctgatctgtcaaggggcccagctcggggcacggactgaccgcactggc gagaccgccctgcatttggctgcccgctatgctagagcggatgcagccaagcgtctcctg gatgctggggcggacaccaacgcccaggatcattcgggccgcacccccctgcacaccgca gtgacagctgatgcccagggtgtcttccagattctcatcaggaaccgctccactgacctg gatgcccgaatggcagatggctctactgcactgatcctggcagcccgcctggcagtggag ggcatggtggaagagctcatcgccagccatgccgatgtcaatgcagtggatgagcttggg aaatctgccttacactgggctgcagctgtgaacaacgtggaggctaccttggctctgctg aaaaatggagccaacaaggacatgcaggacagcaaggaagagacgccgctgttcttggcc gctcgggagggcagctatgaggctgccaagctgctgctggatcatctcgccaaccgggag atcacagatcacttggacaggctgccccgggacgtggcccaggagcggctgcaccaggac attgtgcggttgctggaccagcccagtggacctcgaagtccctctggtccccatggctta gggccattgctctgcccaccaggggccttccttcctggcctcaaagcggtgcagtctggg accaagaagagcaggaggccacctggcaagaccgggctggggccacagggaactcgtggt cggggcaagaagctgacactagcctgtccaggacctctggcagacagctctgtcacactg tcaccggtggactctctggactcaccacggcctttcagtgggccccctgcttcccctgga ggcttccccttggagggcccctatgccaccacggccaccgcggtgtccttggcacagcta ggcgcaagtagggcgggtcctctggggcgccagcctcctgggggctgtgtgctcagcttt ggtctgctcaatcctgtagctgttcccctcgactgggccaggctgcctccacctgcccct ccagggccctcattcctgctgcccctggctccgggaccccagttgctcaacccaggagcc ccagtttctccccaagagcggcccccaccctacctggctgctccaggacatggagaggaa tatcctgcagcaggaacccgcagtagccccaccaaggcccgcttcctgcgggttcccagc gagcatccttatttgaccccgtctcctgagtccccagagcactgggccagcccatccccc ccatccctctcagactggtctgactcaacacctagcccagcaactgctaccaatgccaca gcctctggagccctgcctgctcagccacaccccatatctgttccctccctccctcagtcc cagactcagctgggaccccaaccagaagttacccccaagaggcaggtgatggcctaa

Mus musculus (house mouse): 18132 Help Entry 18132             CDS       T01002                                  Symbol Notch4, Int-3, Int3, N4 Name (RefSeq) notch 4   KO K20996   Notch 4 Organism mmu  Mus musculus (house mouse) Pathway mmu01522   Endocrine resistance mmu04330   Notch signaling pathway mmu04919   Thyroid hormone signaling pathway mmu05165   Human papillomavirus infection mmu05200   Pathways in cancer mmu05206   MicroRNAs in cancer mmu05224   Breast cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     18132 (Notch4)  09150 Organismal Systems   09152 Endocrine system    04919 Thyroid hormone signaling pathway     18132 (Notch4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     18132 (Notch4)    05206 MicroRNAs in cancer     18132 (Notch4)   09162 Cancer: specific types    05224 Breast cancer     18132 (Notch4)   09172 Infectious disease: viral    05165 Human papillomavirus infection     18132 (Notch4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     18132 (Notch4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  EGF hEGF EGF_TEN EGF_CA Ank Ank_2 Notch Ank_3 Ank_4 Ank_5 EGF_3 EGF_2 NODP EGF_Teneurin NOD Gurken_M Ank_KRIT1 SPE9_EGF_3rd EGF_MSP1_1 EGF_DL_JAG Motif Other DBs NCBI-GeneID:  18132 NCBI-ProteinID:  NP_035059 MGI:  107471 Ensembl:  ENSMUSG00000015468 UniProt:  P31695 LinkDB All DBs Position 17:34783257..34807517 Genome browser AA seq 1964 aa AA seqDB search MQPQLLLLLLLPLNFPVILTRELLCGGSPEPCANGGTCLRLSRGQGICQCAPGFLGETCQ FPDPCRDTQLCKNGGSCQALLPTPPSSRSPTSPLTPHFSCTCPSGFTGDRCQTHLEELCP PSFCSNGGHCYVQASGRPQCSCEPGWTGEQCQLRDFCSANPCANGGVCLATYPQIQCRCP PGFEGHTCERDINECFLEPGPCPQGTSCHNTLGSYQCLCPVGQEGPQCKLRKGACPPGSC LNGGTCQLVPEGHSTFHLCLCPPGFTGLDCEMNPDDCVRHQCQNGATCLDGLDTYTCLCP KTWKGWDCSEDIDECEARGPPRCRNGGTCQNTAGSFHCVCVSGWGGAGCEENLDDCAAAT CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHVNAQCSTNPLTGSTLCICQPG YSGSTCHQDLDECQMAQQGPSPCEHGGSCINTPGSFNCLCLPGYTGSRCEADHNECLSQP CHPGSTCLDLLATFHCLCPPGLEGRLCEVEVNECTSNPCLNQAACHDLLNGFQCLCLPGF TGARCEKDMDECSSTPCANGGRCRDQPGAFYCECLPGFEGPHCEKEVDECLSDPCPVGAS CLDLPGAFFCLCRPGFTGQLCEVPLCTPNMCQPGQQCQGQEHRAPCLCPDGSPGCVPAED NCPCHHGHCQRSLCVCDEGWTGPECETELGGCISTPCAHGGTCHPQPSGYNCTCPAGYMG LTCSEEVTACHSGPCLNGGSCSIRPEGYSCTCLPSHTGRHCQTAVDHCVSASCLNGGTCV NKPGTFFCLCATGFQGLHCEEKTNPSCADSPCRNKATCQDTPRGARCLCSPGYTGSSCQT LIDLCARKPCPHTARCLQSGPSFQCLCLQGWTGALCDFPLSCQKAAMSQGIEISGLCQNG GLCIDTGSSYFCRCPPGFQGKLCQDNVNPCEPNPCHHGSTCVPQPSGYVCQCAPGYEGQN CSKVLDACQSQPCHNHGTCTSRPGGFHCACPPGFVGLRCEGDVDECLDRPCHPSGTAACH SLANAFYCQCLPGHTGQRCEVEMDLCQSQPCSNGGSCEITTGPPPGFTCHCPKGFEGPTC SHKALSCGIHHCHNGGLCLPSPKPGSPPLCACLSGFGGPDCLTPPAPPGCGPPSPCLHNG TCTETPGLGNPGFQCTCPPDSPGPRCQRPGASGCEGRGGDGTCDAGCSGPGGDWDGGDCS LGVPDPWKGCPPHSQCWLLFRDGRCHPQCDSEECLFDGYDCEIPLTCIPAYDQYCRDHFH NGHCEKGCNNAECGWDGGDCRPEGEDSEGRPSLALLVVLRPPALDQQLLALARVLSLTLR VGLWVRKDSEGRNMVFPYPGTRAKEELSGARDSSSWERQAPPTQPLGKETESLGAGFVVV MGVDLSRCGPEHPASRCPWDSGLLLRFLAAMAAVGALEPLLPGPLLAAHPQAGTRPSANQ LPWPILCSPVVGVLLLALGALLVLQLIRRRRREHGALWLPPGFIRRPQTQQAPHRRRPPL GEDNIGLKALKPEAEVDEDGVAMCSGPEEGEAEETASASRCQLWPLNSGCGELPQAAMLT PPQECESEVLDVDTCGPDGVTPLMSAVFCGGVQSTTGASPQRLGLGNLEPWEPLLDRGAC PQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHTAVAADAREVCQL LLASRQTTVDARTEDGTTPLMLAARLAVEDLVEELIAARADVGARDKRGKTALHWAAAVN NARAARSLLQAGADKDAQDSREQTPLFLAAREGAVEVAQLLLELGAARGLRDQAGLAPGD VARQRSHWDLLTLLEGAGPTTQEARAHARTTPGGGAAPRCRTLSAGARPRGGGACLQART WSVDLGARGGKVYARCRSRSGSCGGPTTRGRRFSAGSRGRRGARASQDDWPRDWVALEAC GSACSAPIPPPSLTPSPERGSPQVAWGLPVHQEIPLNSVVRNLN NT seq 5895 nt NT seq  +upstreamnt  +downstreamnt atgcagccccagttgctgctgctgctgctcttgccactcaatttccctgtcatcctgacc agagagcttctgtgtggaggatccccagagccctgtgccaacggaggcacctgcctgagg ctatctcggggacaagggatctgccagtgtgcccctggatttctgggtgagacttgccag tttcctgacccctgcagggatacccaactctgcaagaatggtggcagctgccaagccctg ctccccacacccccaagctcccgtagtcctacttctccactgacccctcacttctcctgc acctgcccctctggcttcaccggtgatcgatgccaaacccatctggaagagctctgtcca ccttctttctgttccaacgggggtcactgctatgttcaggcctcaggccgcccacagtgc tcctgcgagcctgggtggacaggtgagcaatgccagctccgagacttctgctcagccaac ccctgtgccaacggaggcgtgtgcctggccacatacccccagatccagtgccgctgtcca cctgggttcgagggtcacacctgtgaacgcgacatcaacgagtgcttcctggagccggga ccctgccctcagggcacctcctgccataacaccttgggttcctaccagtgtctctgccct gtggggcaggaaggtccccagtgcaagctcaggaagggagcctgccctcctggaagctgt ctcaatgggggcacctgccagctggtcccagagggacactccacctttcatctctgcctc tgtcccccaggtttcacggggctggactgtgagatgaacccagatgactgtgtcaggcac cagtgtcagaacggggccacctgtctggatgggctggacacctacacctgcctctgcccc aagacatggaagggctgggactgctctgaagatatagatgaatgtgaagcccggggtccc cctcgctgcaggaacggtggcacctgccagaacacagctggcagctttcactgtgtgtgc gtgagtggctggggaggcgcaggctgtgaggagaacctggatgactgtgcagctgccacc tgtgccccgggatccacctgcatcgaccgtgtgggctccttctcctgcctctgcccacct ggacgcacaggcctcctgtgccacctggaagacatgtgtttgagtcagccgtgccacgtg aatgcccagtgcagcaccaaccctctgacaggctccaccctctgcatatgccagcctggc tactcaggatccacctgtcaccaagatctggatgagtgccaaatggcccagcaaggaccc agtccctgcgaacatggcggctcctgcatcaacacccctggctccttcaactgcctctgc ctgcctggttacacgggctcccgctgtgaagctgaccacaatgagtgcctgtcacagccc tgccacccaggcagcacctgcctggacctgcttgcaaccttccactgcctctgcccacca ggcttggaagggaggctctgtgaggtggaggtcaatgagtgcacctctaatccctgcctg aaccaagctgcctgccatgacctgctcaacggcttccagtgcctctgccttcctggattc accggcgcccgatgtgagaaagacatggacgagtgtagcagcaccccctgtgccaatggg gggcgctgccgagaccagcctggagccttctactgcgagtgtctcccaggctttgaaggg ccacactgtgagaaagaagtggacgaatgtctgagtgacccctgccccgtgggagccagc tgccttgatctccccggagcattcttctgcctctgccgtcctggtttcacaggtcaactt tgtgaggttcccttgtgcacccccaacatgtgccaacctggacagcaatgccaaggtcag gaacacagagccccctgcctctgccctgacggaagtcctggctgtgttcctgccgaggac aactgcccctgtcaccatggccattgccagagatccttgtgtgtgtgtgatgagggctgg actggaccagaatgcgagacagaactgggtggctgcatctccacaccctgtgcccatggg gggacctgccacccacagccatctggctacaactgtacctgccctgcaggctacatgggg ttgacctgtagtgaggaggtgacagcttgtcactcagggccctgtctcaatggtggctcc tgcagcatccgtcctgagggctattcctgcacctgccttccaagtcacacaggtcgccac tgccagactgccgtggaccactgtgtgtctgcctcgtgcctcaatgggggtacctgtgtg aacaagcctggcactttcttctgcctctgtgccactggcttccaggggctgcactgtgag gagaagactaaccccagctgtgcagacagcccctgcaggaacaaggcaacctgccaagac acacctcgaggggcccgctgcctctgcagccctggctatacaggaagcagctgccagact ctgatagacttgtgtgcccggaagccctgtccacacactgctcgatgcctccagagtggg ccctcgttccagtgcctgtgcctccagggatggacaggggctctctgtgacttcccactg tcctgccagaaggccgcgatgagccaaggcatagagatctctggcctgtgccagaatgga ggcctctgtattgacacgggctcctcctatttctgccgctgccctcctggattccaaggc aagttatgccaggataatgtgaacccctgtgagcccaatccctgccatcacgggtctacc tgtgtgcctcagcccagtggctatgtctgccagtgtgccccaggctatgagggacagaac tgctcaaaagtacttgacgcttgtcagtcccagccctgccacaaccacggaacctgtacc tccaggcctggaggcttccactgtgcctgccctccaggcttcgtgggactgcgctgtgag ggagatgtggatgagtgtctggaccggccctgtcacccctcgggcactgcagcttgccac tctttagccaacgccttctactgccagtgtctgcctgggcacacaggccagcggtgtgag gtggagatggacctctgtcagagccaaccctgctccaatggaggatcctgtgagatcaca acagggccaccccctggcttcacctgtcactgccccaagggttttgaaggccccacctgc agccacaaagccctttcctgcggcatccatcactgccacaatggaggcctatgtctgccc tcccctaagccagggtcaccaccactctgtgcctgcctcagtggttttgggggccctgac tgtctgacacctccagctccaccgggctgcggtcccccctcaccctgcctgcacaatggt acctgcactgagacccctgggttgggcaacccgggctttcaatgcacctgccctcctgac tctccagggccccggtgtcaaaggccaggggcaagtgggtgtgagggccgaggtggtgat gggacctgcgatgctggctgcagtggcccaggaggagactgggatggaggggactgttcc ctgggggtcccagacccctggaagggctgtcccccgcattcccagtgctggcttctgttc cgggacggacggtgtcacccgcagtgtgactctgaggagtgtctctttgatggctacgac tgtgaaatccctctaacctgcatcccagcctatgaccagtactgccgagatcacttccac aacgggcactgtgagaaaggctgcaataacgctgaatgtggctgggacgggggagactgc agaccagaaggggaagactcagaggggaggccctccctggccctgctggtggtgctgagg cccccagccctggatcagcagctgcttgccctggcacgagtgctgtccctgactctgagg gtcggtctctgggtgaggaaggacagtgaaggcaggaacatggtgttcccctatcctggg acccgggccaaagaggagctgagtggagctagggattcctcttcatgggaaagacaagcc cctcccactcagcccctgggcaaggagacagagtctcttggtgcagggtttgtggtagtg atgggagtggatctgtcccgctgtggtccggaacatcctgcgtcccgctgcccctgggac tctggactcctgctgcgcttccttgcagcaatggcagcagtgggagctctggagcccctg ctgcctggacccttgctggcggctcaccctcaagcagggaccaggccctctgccaaccag cttccctggcccattctatgttcaccagtggttggggtgcttctcctggcccttggggcc cttctcgtcctccagctcattcggcgacggcgacgagaacatggggccctgtggctgccc cctggtttcattcgaaggcctcagacacagcaggcaccccaccggcggaggcccccactg ggcgaggacaacattggtcttaaggcactgaagccagaggccgaagtggatgaggatgga gtggccatgtgctcgggccctgaagagggagaggctgaagaaacagcctcagcctccagg tgccagctttggccgctcaacagcggctgtggagagctcccccaggcagccatgctgacc cctcctcaggagtgtgaatcggaggttctggatgtggacacctgtggacctgatggggtg acacccctgatgtcagccgtcttctgtgggggagtgcagtccacgactggggctagtcca cagagactggggctaggaaatctggaaccctgggaaccactgctggatagaggggcctgc ccccaggctcacactgtgggcactggagagacgcctctgcacctagctgccagattctct cggccaaccgctgcccgccgcctccttgaggctggagccaaccccaaccagccagaccgc gctgggcgcaccccacttcacactgctgtggctgccgacgctcgggaggtttgccagctc ctattggccagcagacagactacggtggacgcccgcacagaggacgggactacacctttg atgctggctgccaggctggccgtggaggacctggttgaagaattgatcgcagcccgagca gatgtaggagccagggataaaaggggaaaaactgcactgcactgggccgctgctgtgaac aacgcccgagccgcccgctctctcctccaggctggagcggataaagatgcccaggacagt agggaacagacgccgcttttcctggcagcgcgcgaaggagccgtggaggtggcgcagctg ttgctggagctcggggcggcccggggactgcgagaccaggccgggctggccccaggagat gtggcccgccagcgcagtcactgggacctgctaacgctgctggaaggggctggaccgact acgcaggaggcccgtgcgcacgcacgcaccacgccggggggcggggccgcgccgcgctgc cggacgctgtctgcgggagcgcgcccgcgcgggggcggagcctgtctgcaggctcgcact tggtcggtggacttgggagcgcgcggagggaaggtgtatgctcgctgccggagccgatct ggaagctgcggaggccccaccacgcgcggccgcaggttctccgcgggctcccgtggacga cgcggggctagggcatcacaggatgactggcctcgcgactgggtggccctggaagcctgc ggctccgcctgcagtgcgccgatcccgcctcccagcctgaccccgtccccagaacgtgga tcccctcaagttgcctggggtcttccagttcaccaagagattcccttaaactcggttgta agaaatctgaactag

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