Mus musculus (house mouse): 22030 Help Entry 22030             CDS       T01002                                  Symbol Traf2 Name (RefSeq) TNF receptor-associated factor 2   KO K03173   TNF receptor-associated factor 2 [EC:2.3.2.27] Organism mmu  Mus musculus (house mouse) Pathway mmu04010   MAPK signaling pathway mmu04064   NF-kappa B signaling pathway mmu04071   Sphingolipid signaling pathway mmu04141   Protein processing in endoplasmic reticulum mmu04210   Apoptosis mmu04217   Necroptosis mmu04380   Osteoclast differentiation mmu04621   NOD-like receptor signaling pathway mmu04622   RIG-I-like receptor signaling pathway mmu04657   IL-17 signaling pathway mmu04668   TNF signaling pathway mmu04920   Adipocytokine signaling pathway mmu04932   Non-alcoholic fatty liver disease mmu05010   Alzheimer disease mmu05014   Amyotrophic lateral sclerosis mmu05016   Huntington disease mmu05017   Spinocerebellar ataxia mmu05022   Pathways of neurodegeneration - multiple diseases mmu05132   Salmonella infection mmu05135   Yersinia infection mmu05160   Hepatitis C mmu05163   Human cytomegalovirus infection mmu05167   Kaposi sarcoma-associated herpesvirus infection mmu05168   Herpes simplex virus 1 infection mmu05169   Epstein-Barr virus infection mmu05170   Human immunodeficiency virus 1 infection mmu05200   Pathways in cancer mmu05203   Viral carcinogenesis mmu05222   Small cell lung cancer mmu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     22030 (Traf2)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     22030 (Traf2)    04064 NF-kappa B signaling pathway     22030 (Traf2)    04668 TNF signaling pathway     22030 (Traf2)    04071 Sphingolipid signaling pathway     22030 (Traf2)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     22030 (Traf2)    04217 Necroptosis     22030 (Traf2)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     22030 (Traf2)    04622 RIG-I-like receptor signaling pathway     22030 (Traf2)    04657 IL-17 signaling pathway     22030 (Traf2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     22030 (Traf2)   09158 Development and regeneration    04380 Osteoclast differentiation     22030 (Traf2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     22030 (Traf2)    05203 Viral carcinogenesis     22030 (Traf2)   09162 Cancer: specific types    05222 Small cell lung cancer     22030 (Traf2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     22030 (Traf2)    05160 Hepatitis C     22030 (Traf2)    05168 Herpes simplex virus 1 infection     22030 (Traf2)    05163 Human cytomegalovirus infection     22030 (Traf2)    05167 Kaposi sarcoma-associated herpesvirus infection     22030 (Traf2)    05169 Epstein-Barr virus infection     22030 (Traf2)   09171 Infectious disease: bacterial    05132 Salmonella infection     22030 (Traf2)    05135 Yersinia infection     22030 (Traf2)   09164 Neurodegenerative disease    05010 Alzheimer disease     22030 (Traf2)    05014 Amyotrophic lateral sclerosis     22030 (Traf2)    05016 Huntington disease     22030 (Traf2)    05017 Spinocerebellar ataxia     22030 (Traf2)    05022 Pathways of neurodegeneration - multiple diseases     22030 (Traf2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     22030 (Traf2)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     22030 (Traf2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:mmu03019]     22030 (Traf2)    04121 Ubiquitin system [BR:mmu04121]     22030 (Traf2) Enzymes [BR:mmu01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      22030 (Traf2) Messenger RNA biogenesis [BR:mmu03019]  Eukaryotic type   mRNA surveillance and transport factors    mRNA cycle factors     Stress granule specific factors      22030 (Traf2) Ubiquitin system [BR:mmu04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     22030 (Traf2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TRAF_BIRC3_bd zf-TRAF zf-C3HC4 zf-RING_6 zf-C3HC4_2 PIN_9 MATH Cep57_CLD Motif Other DBs NCBI-GeneID:  22030 NCBI-ProteinID:  NP_033448 MGI:  101835 Ensembl:  ENSMUSG00000026942 UniProt:  P39429 Q3U8L1 Q8C6X9 LinkDB All DBs Position 2:complement(25407994..25436952) Genome browser AA seq 501 aa AA seqDB search MAAASVTSPGSLELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTS ILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKE YESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYE VCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRL REHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTA EACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISD FTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDA LLQWPFNQKVTLMLLDHNNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEA KNSYVRDDAIFIKAIVDLTGL NT seq 1506 nt NT seq  +upstreamnt  +downstreamnt atggctgcagccagtgtgacttcccctggctccctagaactgctacagcctggcttctcc aagaccctcctggggaccaggttagaagccaagtacctctgttcagcctgcaaaaacatc ctgcggaggcctttccaggcccagtgtgggcaccgctactgctccttctgcctgaccagc atcctcagctctgggccccagaactgtgctgcctgtgtctatgaaggcctgtatgaagaa ggcatttctattttagagagtagttcggcctttccagataacgctgcccgcagagaggtg gagagcctgccagctgtctgtcccaatgatggatgcacttggaaggggaccttgaaagaa tacgagagctgccacgaaggactttgcccattcctgctgacggagtgtcctgcatgtaaa ggcctggtccgcctcagcgagaaggagcaccacactgagcaggaatgccccaaaaggagc ctgagctgccagcactgcagagcaccctgtagccacgtggacctggaggtacactatgag gtctgccccaagtttcccttaacctgtgatggctgtggcaagaagaagatccctcgggag acgtttcaggaccatgttagagcatgcagcaaatgccgggttctctgcagattccacacc gttggctgttcagagatggtggagactgagaacctgcaggatcatgagctgcagcggcta cgggaacacctagccctactgctgagctcattcttggaggcccaagcctctccaggaacc ttgaaccaggtggggccagagctactccagcggtgccagattttggagcagaagatagca acctttgagaacattgtctgcgtcttgaaccgtgaagtagagagggtagcagtgactgca gaggcttgtagccggcagcaccggctagaccaggacaagattgaggccctgagtaacaag gtgcaacagctggagaggagcatcggcctcaaggacctggccatggctgacctggagcag aaggtctccgagttggaagtatccacctatgatggggtcttcatctggaagatctctgac ttcaccagaaagcgtcaggaagccgtagctggccggacaccagctatcttctccccagcc ttctacacaagcagatatggctacaagatgtgtctacgagtctacttgaatggcgacggc actgggcggggaactcatctgtctctcttcttcgtggtgatgaaaggccccaatgatgct ctgttgcagtggccttttaatcagaaggtaacattgatgttgctggaccataacaaccgg gagcatgtgatcgacgcattcaggcccgatgtaacctcgtcctccttccagaggcctgtc agtgacatgaacatcgccagtggctgccccctcttctgccctgtgtccaagatggaggcc aagaattcctatgtgcgggatgatgcgatcttcatcaaagctattgtggacctaacagga ctctag

Mus musculus (house mouse): 22034 Help Entry 22034             CDS       T01002                                  Symbol Traf6, 2310003F17Rik, C630032O20Rik Name (RefSeq) TNF receptor-associated factor 6   KO K03175   TNF receptor-associated factor 6 [EC:2.3.2.27] Organism mmu  Mus musculus (house mouse) Pathway mmu04010   MAPK signaling pathway mmu04064   NF-kappa B signaling pathway mmu04120   Ubiquitin mediated proteolysis mmu04140   Autophagy - animal mmu04144   Endocytosis mmu04380   Osteoclast differentiation mmu04620   Toll-like receptor signaling pathway mmu04621   NOD-like receptor signaling pathway mmu04622   RIG-I-like receptor signaling pathway mmu04657   IL-17 signaling pathway mmu04722   Neurotrophin signaling pathway mmu04936   Alcoholic liver disease mmu05132   Salmonella infection mmu05133   Pertussis mmu05135   Yersinia infection mmu05140   Leishmaniasis mmu05142   Chagas disease mmu05145   Toxoplasmosis mmu05152   Tuberculosis mmu05160   Hepatitis C mmu05161   Hepatitis B mmu05162   Measles mmu05168   Herpes simplex virus 1 infection mmu05169   Epstein-Barr virus infection mmu05170   Human immunodeficiency virus 1 infection mmu05171   Coronavirus disease - COVID-19 mmu05200   Pathways in cancer mmu05222   Small cell lung cancer mmu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mmu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     22034 (Traf6)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     22034 (Traf6)    04064 NF-kappa B signaling pathway     22034 (Traf6)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     22034 (Traf6)    04140 Autophagy - animal     22034 (Traf6)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     22034 (Traf6)    04621 NOD-like receptor signaling pathway     22034 (Traf6)    04622 RIG-I-like receptor signaling pathway     22034 (Traf6)    04657 IL-17 signaling pathway     22034 (Traf6)   09156 Nervous system    04722 Neurotrophin signaling pathway     22034 (Traf6)   09158 Development and regeneration    04380 Osteoclast differentiation     22034 (Traf6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     22034 (Traf6)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     22034 (Traf6)   09162 Cancer: specific types    05222 Small cell lung cancer     22034 (Traf6)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     22034 (Traf6)    05161 Hepatitis B     22034 (Traf6)    05160 Hepatitis C     22034 (Traf6)    05171 Coronavirus disease - COVID-19     22034 (Traf6)    05162 Measles     22034 (Traf6)    05168 Herpes simplex virus 1 infection     22034 (Traf6)    05169 Epstein-Barr virus infection     22034 (Traf6)   09171 Infectious disease: bacterial    05132 Salmonella infection     22034 (Traf6)    05135 Yersinia infection     22034 (Traf6)    05133 Pertussis     22034 (Traf6)    05152 Tuberculosis     22034 (Traf6)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     22034 (Traf6)    05140 Leishmaniasis     22034 (Traf6)    05142 Chagas disease     22034 (Traf6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     22034 (Traf6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     22034 (Traf6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mmu04131]     22034 (Traf6)    04121 Ubiquitin system [BR:mmu04121]     22034 (Traf6) Enzymes [BR:mmu01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      22034 (Traf6) Membrane trafficking [BR:mmu04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     22034 (Traf6) Ubiquitin system [BR:mmu04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     22034 (Traf6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-C3HC4_3 zf-RING_2 zf-RING_UBOX zf-C3HC4_4 zf-RING_5 SlyX zf-TRAF_2 Tropomyosin_1 DUF4455 PspA_IM30 UPF0242 Sina U-box DUF16 Spc29 Tropomyosin ADIP TMF_DNA_bd PKcGMP_CC Motif Other DBs NCBI-GeneID:  22034 NCBI-ProteinID:  NP_001290202 MGI:  108072 Ensembl:  ENSMUSG00000027164 UniProt:  P70196 LinkDB All DBs Position 2:101508765..101532013 Genome browser AA seq 530 aa AA seqDB search MSLLNCENSCGSSQSSSDCCAAMAASCSAAVKDDSVSGSASTGNLSSSFMEEIQGYDVEF DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD NFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQCQRPFQKCQVNTHIIE DCPRRQVSCVNCAVSMAYEEKEIHDQSCPLANIICEYCGTILIREQMPNHYDLDCPTAPI PCTFSVFGCHEKMQRNHLARHLQENTQLHMRLLAQAVHNVNLALRPCDAASPSRGCRPED PNYEETIKQLESRLVRQDHQIRELTAKMETQSMYVGELKRTIRTLEDKVAEMEAQQCNGI YIWKIGNFGMHLKSQEEERPVVIHSPGFYTGRPGYKLCMRLHLQLPTAQRCANYISLFVH TMQGEYDSHLPWPFQGTIRLTILDQSEALIRQNHEEVMDAKPELLAFQRPTIPRNPKGFG YVTFMHLEALRQGTFIKDDTLLVRCEVSTRFDMGGLRKEGFQPRSTDAGV NT seq 1593 nt NT seq  +upstreamnt  +downstreamnt atgagtctcttaaactgtgagaacagctgcgggtccagccagtcgtccagtgactgctgc gctgccatggccgcctcctgcagcgctgcagtgaaagatgacagcgtgagtggctctgcc agcaccgggaacctctccagctccttcatggaggagatccagggctacgatgtggagttt gacccacctctggagagcaagtatgagtgtcccatctgcttgatggctttacgggaagca gtgcaaacaccatgtggccacaggttctgcaaagcctgcatcatcaaatccataagggat gcagggcacaagtgcccagttgacaatgaaatactgctggaaaatcaactgtttcccgac aattttgcaaagcgagagattctttccctgacggtaaagtgcccaaataaaggctgtttg caaaagatggaactgagacatctcgaggatcatcaagtacattgtgaatttgctctagtg aattgtccccagtgccaacgtcctttccagaagtgccaggttaatacacacattattgag gattgtcccaggaggcaggtttcttgtgtaaactgtgctgtgtccatggcatatgaagag aaagagatccatgatcaaagctgtcctctggcaaatatcatctgtgaatactgtggtaca atcctcatcagagaacagatgcctaatcattatgatctggactgcccaacagctccaatc ccttgcacattcagtgtttttggctgtcatgaaaagatgcagaggaatcacttggcacga cacttgcaagagaatacccagttgcacatgagactgttggcccaggctgttcataatgtt aaccttgctttgcgtccgtgcgatgccgcctctccatcccggggatgtcgtccagaggac ccaaattatgaggaaactatcaaacagttggagagtcgcctagtaagacaggaccatcag atccgggagctgactgccaaaatggaaactcagagtatgtacgtgggcgagctcaaacgg accattcggaccctggaggacaaggttgccgaaatggaagcacagcagtgtaacgggatc tacatttggaagattggcaactttgggatgcacttgaaatcccaagaagaggaaagacct gttgtcatccatagccctggattctacacaggcagacctgggtacaagctgtgcatgcgc ctgcatcttcagttaccgacagctcagcgctgtgcaaactatatatccctttttgtccac acaatgcaaggagaatatgacagccacctcccctggcccttccagggtacaatacgcctt acaattctcgaccagtctgaagcacttataaggcaaaaccacgaagaggtcatggacgcc aaaccagaactgcttgcctttcagcgacccacaatcccacggaaccccaaaggttttggc tatgtaacatttatgcacctggaagccttaagacagggaaccttcattaaggatgataca ttactagtgcgctgtgaagtctctacccgctttgacatgggtggccttcggaaggagggt ttccagccacgaagtactgatgcgggggtgtag

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