Mus musculus (house mouse): 223864
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Entry
223864 CDS
T01002
Symbol
Rapgef3, 2310016P22Rik, 9330170P05Rik, Epac, Epac1
Name
(RefSeq) Rap guanine nucleotide exchange factor (GEF) 3
KO
K08014
Rap guanine nucleotide exchange factor 3
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04015
Rap1 signaling pathway
mmu04024
cAMP signaling pathway
mmu04072
Phospholipase D signaling pathway
mmu04261
Adrenergic signaling in cardiomyocytes
mmu04670
Leukocyte transendothelial migration
mmu04720
Long-term potentiation
mmu04726
Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
223864 (Rapgef3)
04072 Phospholipase D signaling pathway
223864 (Rapgef3)
04024 cAMP signaling pathway
223864 (Rapgef3)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
223864 (Rapgef3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
223864 (Rapgef3)
09156 Nervous system
04726 Serotonergic synapse
223864 (Rapgef3)
04720 Long-term potentiation
223864 (Rapgef3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
cNMP_binding
DEP
RasGEF_N
Motif
Other DBs
NCBI-GeneID:
223864
NCBI-ProteinID:
NP_659099
MGI:
2441741
Ensembl:
ENSMUSG00000022469
UniProt:
Q8VCC8
LinkDB
All DBs
Position
15:complement(97637886..97666300)
Genome browser
AA seq
918 aa
AA seq
DB search
MKVSWPGENHWQVGPAVVESPAVGAPQVGGLPDVVPEGTLLNMVLKRMHRPRCCSYQLVF
EHRRPSCIQGLRWTPLTNSEDSLDFRVSLEQATTEHVHKAGKLLHRHLLATYPTLIRDRK
YHLRLYRHCCSGRELVDGILALGLGVHSRSQAVGICQVLLDEGALCHVKHDWTFQDRDAQ
FYRFPGPEPEPTGTQDVEEELVEAMALLSQRGPDALLTVALRKPPGQRTDEELDLIFEEL
LHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGL
VTTLHEGDDFGQLALVNDAPRAATIILRENNCHFLRVDKQDFNRIIKDVEAKTMRLEEHG
KVVLVLERTSQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMRPDSSAHDPTETFLSD
FLLTHSVFMPSTQLFTALLHHFHVEPADPAGGSEQEHSTYICNKRQQILRLVGRWVALYS
PMLHSDPVATSFLQKLSDLVSRDARLSNLLREQYPERRRHHRLENGCGNVSPQTKARNAP
VWLPNQEEPLPSSAGAIRVGDKVPYDICRPDHSVLTLHLPVTASVREVMAALAHEDHWTK
GQVLVKVNSAGDVVGLQPDARGVATSLGLNERLFVVDPQEVHELTPHPEQLGPTLGSSEM
LDLVSAKDLAGQLTDHDWNLFNRIHQVQEHLRDVTTANLERFMRRFNELQYWVATELCLC
PVPGSRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYS
ALERLLDPSWNHRVYRLALTKLSPPVIPFMPLLLKDVTFIHEGNHTLVENLINFEKMRMM
ARAVRMLHHCRSHSTAPLSPLRSRVSHIHEDSQGSRISTCSEQSLSTRSPASTWAYVQQL
KVIDNQRELSRLSRELEP
NT seq
2757 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtcagctggccaggtgagaaccactggcaggtgggcccagctgtggtggagagt
ccagctgtgggggcaccgcaggtgggaggtctcccggacgtggttccggagggcacgctg
ctcaatatggtgttgaagagaatgcaccgtccccgctgctgctcttaccagctagtgttc
gagcaccggcgccccagctgcatccagggactccgctggacaccacttaccaacagcgag
gactccctggatttcagagtgagtctggagcaggccaccacagagcatgtgcacaaggca
gggaagctcctgcaccgccatctcttggccacgtaccctaccctcatccgagacagaaaa
taccatctgcgactatatcggcattgctgctctggccgggagctagtggatgggatcttg
gctctggggcttggggtccactcacggagccaagccgtgggcatctgccaagtgttgctg
gatgagggtgccctttgtcatgtaaaacatgactggaccttccaggaccgagatgcccaa
ttctacaggttccctggaccggagcccgagcctacaggaactcaagatgtggaagaggag
cttgttgaggctatggccctcctgtcccagcgagggcctgatgccctactcaccgtggcg
ctccggaagcccccaggtcagcgtacggatgaagaactggacctgatctttgaagagctg
ctgcatatcaaggcggtggcacacctttctaactcggtgaagcgggaactagctgctgtt
ctgctctttgaaccacacagcaaggcaggaactgtgttgttcagccagggggacaagggt
acctcgtggtacattatctggaagggatctgtcaatgtggtgacccatggcaaggggctg
gtgaccacgttgcacgagggagatgactttggacagctggctctggtgaacgacgcacct
cgggcagccaccatcatccttcgagaaaataactgtcactttctgcgtgtggacaagcag
gacttcaaccgcatcatcaaggatgtggaagcaaaaaccatgagactggaagaacacggc
aaagtggtcttagttctggagagaacctctcagggtgctggcccttcccgtcccccgacc
ccaggcaggaaccggtatacggtcatgtctggcaccccagagaaaatcctagaactgctg
ttggaggctatgagaccggattccagtgctcatgacccaacagagacgttcctcagtgac
ttcctgctgacccacagtgtcttcatgcccagcacccagctcttcactgccctcctgcac
cacttccacgtggagccagcagaccctgctggaggcagcgagcaggagcacagcacctac
atctgcaacaagaggcagcagatcctgcggctagttggccgatgggtggccctgtatagc
ccgatgctccactcggatcccgtggccaccagcttcctccagaaactctcagacctggtg
agcagagatgcccgacttagcaacttgctgagggaacagtatccagagagacggcgacac
cacaggttggaaaatggctgtgggaacgtatctcctcagaccaaggcccggaatgcacct
gtttggctccctaaccaggaggaacccctcccaagcagcgcgggtgccatccgagttggg
gacaaagtcccctacgacatctgcagacctgaccactcagtgctgaccctgcacctgccg
gtgacggcctcggtgagagaagtgatggcagctttggcccatgaggaccactggaccaag
ggacaggtgttggtgaaggtcaattctgccggtgatgtcgttggcttgcagccagatgcc
cgtggtgtggccacatccctggggctcaacgagcggctctttgttgtcgacccacaggaa
gtgcatgagctgaccccacaccctgagcagctgggccccactctgggttcttctgagatg
ctggacctagtgagcgccaaggacctggcaggccagctgaccgaccatgactggaacctc
ttcaacaggatccaccaggtgcaggagcacctgcgggatgtcaccaccgcgaacctggag
cgcttcatgcgccgcttcaacgagctgcagtactgggtggccacagagctctgtctctgc
cctgttcctggctcccgggctcagctactcaggaagttcatcaagctggcagcccacctc
aaggagcagaagaacctcaactctttctttgcggtcatgtttggcctcagcaactcggcc
atcagccggctggcccacacctgggagcgcctgccccataaagtacggaagctgtactca
gccctggaaaggttgctggacccttcctggaaccaccgagtgtaccgattggctctcacc
aagctctcccctcctgtcatccccttcatgcccctgctgctcaaagacgtgaccttcatc
catgaggggaaccacacactggtagagaacctcatcaactttgagaagatgcggatgatg
gccagagcggtgcggatgcttcaccactgccgaagtcacagtaccgcgcctctatcacca
ctcagaagccgagtgtcccacatccacgaggacagccagggatcaaggatctccacgtgt
tctgagcagtccctgagcacccggagtccagccagcacctgggcttatgtccagcagctg
aaggtcattgacaaccagcgggaactgtcccgcctctcccgggagctggaaccatga
Mus musculus (house mouse): 56508
Help
Entry
56508 CDS
T01002
Symbol
Rapgef4, 1300003D15Rik, 5730402K07Rik, 6330581N18Rik, EPAC_2, Epac-2, Epac2, mKIAA4040
Name
(RefSeq) Rap guanine nucleotide exchange factor (GEF) 4
KO
K04351
Rap guanine nucleotide exchange factor 4
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04015
Rap1 signaling pathway
mmu04024
cAMP signaling pathway
mmu04072
Phospholipase D signaling pathway
mmu04261
Adrenergic signaling in cardiomyocytes
mmu04670
Leukocyte transendothelial migration
mmu04911
Insulin secretion
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
56508 (Rapgef4)
04072 Phospholipase D signaling pathway
56508 (Rapgef4)
04024 cAMP signaling pathway
56508 (Rapgef4)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
56508 (Rapgef4)
09152 Endocrine system
04911 Insulin secretion
56508 (Rapgef4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
56508 (Rapgef4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
56508 (Rapgef4)
Membrane trafficking [BR:
mmu04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
Rab associated proteins
56508 (Rapgef4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
cNMP_binding
DEP
RasGEF_N
Motif
Other DBs
NCBI-GeneID:
56508
NCBI-ProteinID:
NP_001191094
MGI:
1917723
Ensembl:
ENSMUSG00000049044
UniProt:
Q9EQZ6
A2ASW4
Q571A8
Structure
PDB
LinkDB
All DBs
Position
2:71811559..72087818
Genome browser
AA seq
1011 aa
AA seq
DB search
MVAAHAAHSQSSAEWIACLDKRPLERSSEDVDIIFTRLKGVKAFEKFHPNLLRQICLCGY
YENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDN
TPRHATIVTRESSELLRIEQEDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENT
PLIEPHVPLRPAHTITKVPSEKILRAGKILRIAILSRAPHMIRDRKYHLKTYRQCCVGTE
LVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYLFYRFLDDEREDAPLP
TEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHL
STTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD
FGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV
PAGNRAANQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEATDSVLNDFVMMHCVF
MPNTQLCPALVAHYHAQPSQGTEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMA
FLEEFYVSVSDDARMMAAFKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQK
RQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLGSGEGLIIVKMNSGGEK
VVLKSNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGTFELMSSKDLAYQM
TTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKR
VQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLM
DPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART
VRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
NT seq
3036 nt
NT seq
+upstream
nt +downstream
nt
atggtcgctgcgcacgctgcacactctcagtcctcggccgagtggatcgcctgcctggat
aaaaggccgttggagcgatctagtgaagatgtggacataattttcacgcggctgaaagga
gttaaagcttttgagaaatttcacccaaacctccttcgtcagatttgtttatgcggttac
tatgagaacctggaaaaaggaatcacactgtttcgccaaggggatattggaaccaactgg
tatgctgtcctggctgggtctttggatgttaaagtgtctgagaccagcagtcaccaggat
gcggtgaccatctgcactctgggaattgggacagcctttggagagtccattctggataac
acccctcgccatgcaaccatcgttaccagggagagcagcgaacttctccgcattgagcag
gaggacttcaaggcactatgggagaaataccgacagtatatggccggacttctggctcct
ccctatggtgttatggaaacgggctctaacaatgacaggattcctgacaaggagaataca
cctctcattgaaccccacgttcctctccgtcctgctcacaccattaccaaggtcccttca
gagaagatcctcagagctggaaaaattttacgaattgccattctctctcgagctccccac
atgataagagacagaaagtaccacctaaagacatacagacaatgctgtgttgggactgag
ctggtagactggatgatacagcagacatcctgtgttcactcgcggactcaagctgttggc
atgtggcaagtcttgctggaagatggtgtcctcaaccatgtggaccaggagcgccatttc
caagacaaatatttattttatcgatttctggatgacgagcgtgaggatgcccctttgcct
actgaggaagagaagaaggagtgtgatgaagaacttcaggacaccatgctgctgctctca
cagatgggccctgacgcccacatgagaatgatcctgcgaaaaccacctggccagaggact
gtggatgacctagagattatctacgacgagctccttcatattaaagccttatcccatctc
tctaccacagtgaaacgggagttagcaggtgttctcatttttgagtctcacgccaaagga
ggaactgtgttgtttaaccagggggaagaaggtacctcctggtacatcattctgaaagga
tccgtgaatgtagtcatttatggcaagggtgtggtctgcaccctgcacgaaggagatgac
tttggcaagttagctctagtgaacgatgctccaagagctgcctccattgttcttcgggaa
gataattgtcacttcctaagagtcgacaaggaagacttcaatcggattctgagggacgtt
gaggcgaatacagtcagacttaaagaacatgaccaagatgtcttggtactggagaaggtc
ccagcagggaacagagctgctaatcaaggaaactcacagcctcagcaaaagtatactgtg
atgtcaggaacacctgaaaagattttagagcattttctagaaacaatacgccttgagcca
tcgttgaatgaagcaacagattcggttttaaatgactttgttatgatgcactgtgttttt
atgccaaatacccagctttgccctgcccttgtggcccattaccacgcacagccttctcaa
ggtaccgagcaggagagaatggattatgccctcaacaacaagaggcgggtcatccgcttg
gtcctgcagtgggcggccatgtatggcgatctcctccaagaagatgatgtggccatggcc
ttcctggaggagttctatgtgtctgtatcagatgacgcacggatgatggctgccttcaag
gagcagctgccagagctggagaagattgtcaagcaaatctcagaagacgcaaaagctcca
cagaagaagcacaaggtgcttttgcaacagttcaacacaggtgacgagagggcccagaag
cgtcagcctattcgtggctctgatgaggttttgttcaaggtctactgcatcgaccacacc
tatactaccattcgtgtgccggtagctgcctcggtgaaggaagtcatcagtgcagtagct
gacaaactgggctcaggggaaggcctgatcatcgtcaagatgaactctggaggagaaaag
gtggtgctgaaatctaatgatgtttcagtatttacgacgctcaccattaatggacgcctg
tttgcctgcccgagagagcaattcgactcactgactcccttgccggaacaggaaggcccg
accactgggacagtgggaacatttgagctgatgagctcgaaagacctggcgtaccagatg
acaacctacgattgggaactcttcaactgtgtgcatgagctggagctaatctaccacaca
tttggaaggcataattttaaaaagaccacggcaaacttggatttgttcctgaggaggttt
aatgaaattcagttttgggttgtcactgaggtctgcctttgttcccagctcagcaaacgt
gttcagcttttgaaaaaatttatcaagatagcggctcactgcaaggagtacaaaaatcta
aattcctttttcgccatcgtcatgggactcagcaacgtggccgtgagccgcttggcacta
acgtgggagaaactgccgagcaagtttaagaagttctatgcggagtttgagagcttgatg
gatccttccagaaaccacagggcatacaggctgacagcagccaagctggagccccctctc
atccctttcatgcccttgcttattaaagatatgacatttactcatgaggggaacaagacg
ttcattgacaatctagtaaactttgaaaaaatgcgcatgattgcaaacactgccagaaca
gtacggtactacaggagccagcccttcaatccggatgccgctcaagctaataagaaccat
caggatgtccggagttatgtacggcaattaaatgtgattgacaaccagagaactttatca
cagatgtcacacagattagagcctcgaaggccatag
DBGET
integrated database retrieval system
