Mus musculus (house mouse): 224129 Help Entry 224129            CDS       T01002                                  Symbol Adcy5, Ac5 Name (RefSeq) adenylate cyclase 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism mmu  Mus musculus (house mouse) Pathway mmu00230   Purine metabolism mmu01100   Metabolic pathways mmu01522   Endocrine resistance mmu04015   Rap1 signaling pathway mmu04022   cGMP-PKG signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04072   Phospholipase D signaling pathway mmu04114   Oocyte meiosis mmu04211   Longevity regulating pathway mmu04213   Longevity regulating pathway - multiple species mmu04261   Adrenergic signaling in cardiomyocytes mmu04270   Vascular smooth muscle contraction mmu04371   Apelin signaling pathway mmu04540   Gap junction mmu04611   Platelet activation mmu04713   Circadian entrainment mmu04714   Thermogenesis mmu04723   Retrograde endocannabinoid signaling mmu04724   Glutamatergic synapse mmu04725   Cholinergic synapse mmu04726   Serotonergic synapse mmu04727   GABAergic synapse mmu04728   Dopaminergic synapse mmu04750   Inflammatory mediator regulation of TRP channels mmu04911   Insulin secretion mmu04912   GnRH signaling pathway mmu04913   Ovarian steroidogenesis mmu04914   Progesterone-mediated oocyte maturation mmu04915   Estrogen signaling pathway mmu04916   Melanogenesis mmu04918   Thyroid hormone synthesis mmu04921   Oxytocin signaling pathway mmu04923   Regulation of lipolysis in adipocytes mmu04924   Renin secretion mmu04925   Aldosterone synthesis and secretion mmu04926   Relaxin signaling pathway mmu04927   Cortisol synthesis and secretion mmu04928   Parathyroid hormone synthesis, secretion and action mmu04934   Cushing syndrome mmu04935   Growth hormone synthesis, secretion and action mmu04970   Salivary secretion mmu04971   Gastric acid secretion mmu04972   Pancreatic secretion mmu04976   Bile secretion mmu05012   Parkinson disease mmu05030   Cocaine addiction mmu05031   Amphetamine addiction mmu05032   Morphine addiction mmu05034   Alcoholism mmu05163   Human cytomegalovirus infection mmu05166   Human T-cell leukemia virus 1 infection mmu05200   Pathways in cancer mmu05207   Chemical carcinogenesis - receptor activation mmu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mmu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     224129 (Adcy5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     224129 (Adcy5)    04371 Apelin signaling pathway     224129 (Adcy5)    04072 Phospholipase D signaling pathway     224129 (Adcy5)    04024 cAMP signaling pathway     224129 (Adcy5)    04022 cGMP-PKG signaling pathway     224129 (Adcy5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     224129 (Adcy5)   09144 Cellular community - eukaryotes    04540 Gap junction     224129 (Adcy5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     224129 (Adcy5)    04062 Chemokine signaling pathway     224129 (Adcy5)   09152 Endocrine system    04911 Insulin secretion     224129 (Adcy5)    04923 Regulation of lipolysis in adipocytes     224129 (Adcy5)    04912 GnRH signaling pathway     224129 (Adcy5)    04913 Ovarian steroidogenesis     224129 (Adcy5)    04915 Estrogen signaling pathway     224129 (Adcy5)    04914 Progesterone-mediated oocyte maturation     224129 (Adcy5)    04921 Oxytocin signaling pathway     224129 (Adcy5)    04926 Relaxin signaling pathway     224129 (Adcy5)    04935 Growth hormone synthesis, secretion and action     224129 (Adcy5)    04918 Thyroid hormone synthesis     224129 (Adcy5)    04928 Parathyroid hormone synthesis, secretion and action     224129 (Adcy5)    04916 Melanogenesis     224129 (Adcy5)    04924 Renin secretion     224129 (Adcy5)    04925 Aldosterone synthesis and secretion     224129 (Adcy5)    04927 Cortisol synthesis and secretion     224129 (Adcy5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     224129 (Adcy5)    04270 Vascular smooth muscle contraction     224129 (Adcy5)   09154 Digestive system    04970 Salivary secretion     224129 (Adcy5)    04971 Gastric acid secretion     224129 (Adcy5)    04972 Pancreatic secretion     224129 (Adcy5)    04976 Bile secretion     224129 (Adcy5)   09156 Nervous system    04724 Glutamatergic synapse     224129 (Adcy5)    04727 GABAergic synapse     224129 (Adcy5)    04725 Cholinergic synapse     224129 (Adcy5)    04728 Dopaminergic synapse     224129 (Adcy5)    04726 Serotonergic synapse     224129 (Adcy5)    04723 Retrograde endocannabinoid signaling     224129 (Adcy5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     224129 (Adcy5)   09149 Aging    04211 Longevity regulating pathway     224129 (Adcy5)    04213 Longevity regulating pathway - multiple species     224129 (Adcy5)   09159 Environmental adaptation    04713 Circadian entrainment     224129 (Adcy5)    04714 Thermogenesis     224129 (Adcy5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     224129 (Adcy5)    05207 Chemical carcinogenesis - receptor activation     224129 (Adcy5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     224129 (Adcy5)    05163 Human cytomegalovirus infection     224129 (Adcy5)   09164 Neurodegenerative disease    05012 Parkinson disease     224129 (Adcy5)   09165 Substance dependence    05030 Cocaine addiction     224129 (Adcy5)    05031 Amphetamine addiction     224129 (Adcy5)    05032 Morphine addiction     224129 (Adcy5)    05034 Alcoholism     224129 (Adcy5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     224129 (Adcy5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     224129 (Adcy5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     224129 (Adcy5) Enzymes [BR:mmu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      224129 (Adcy5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  224129 NCBI-ProteinID:  NP_001012783 MGI:  99673 Ensembl:  ENSMUSG00000022840 UniProt:  P84309 LinkDB All DBs Position 16:34974933..35126108 Genome browser AA seq 1262 aa AA seqDB search MSGSKSVSPPGYAAQTAASPAPRGGPEHRAAWGEADSRANGYPHAPGGSTRGSTKRSGGA VTPQQQQRLASRWRGGDDDEDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDGGRGSRRQR RGAAGGGSTRAPPAGGSGSSAAAAAAAGGTEVRPRSVELGLEERRGKGRAAEELEPGTGI VEDGDGSEDGGSSVASGSGTGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQ SSLTMLMAVLVLVCLVMLAFHAARPPLQIAYLAVLAAAVGVILIMAVLCNRAAFHQDHMG LACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSA LHLAISLHTNSQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARL HSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFT SLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVE MGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGG KAGRIHITKATLNYLNGDYEVEPGCGGDRNAYLKEHSIETFLILSCTQKRKEEKAMIAKM NRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEF LGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQ ITIVPHSLFMLSFYLSCFLLLALVVFVSVIYACVKLFPTPLQTLSRKIVRSKKNSTLVGV FTITLVFLSAFVNMFMCNSKNLVGCLAEEHNITVNQVNACHVMESAFNYSLGDEQGFCGS PQPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIEFIYVLIVEVPGVTLFDNAD LLVTANAIDFSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWK LQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIAN FSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDST YDKAGKTHIKAIADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIW GNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPP LS NT seq 3789 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgctgcacagacagcggcgtcgcca gcgccccggggaggcccggagcatcgcgccgcttggggagaagccgattcccgcgccaat ggctacccccacgcccccgggggatcaacccgcggctccaccaagagatctgggggagcg gtgaccccacaacagcagcagcgcctggccagccgttggcgcggtggcgatgacgacgaa gaccctccactaagcggtgatgaccctctggctgggggcttcggcttcagcttccgctct aagtccgcctggcaggagcgcggtggcgacgacggcggtcgcggcagcaggcggcagcgg cggggcgcggctggagggggcagcacccgggcgccccctgcgggcggcagcggcagttcg gcggcggccgcagcggccgcaggtggcacagaggtgcgcccccgctcggtggagctgggc ctggaggagcgtcgaggaaaaggccgagcggccgaggagctggagcccgggactggcatc gtcgaggatggagacgggtcggaggatggaggcagttctgtggcgtcaggctctgggacc ggcgcggtgctgtcgttgggcgcctgctgcctggccttgctgcagatattccgctctaag aagttcccgtcggacaaactggagcgtctgtaccagcgctacttcttccgcctgaaccag agcagtctcaccatgctcatggccgtgctggtgcttgtgtgcctggtcatgctggctttc cacgcggcgcgccccccgctccagatagcctacctggccgtgttggcagctgctgtgggc gtgatccttatcatggccgtgctctgcaaccgtgcagcgttccaccaggaccacatgggc ctggcctgctatgcgctcattgcagtggtgctggccgtccaggtagtgggcctgttgctg ccacagccacgcagcgcctccgagggcatctggtggaccgtgttcttcatctataccatc tacaccctgctgcctgtgcgcatgagggctgcggtgctcagcggggtgcttctgtcggct ctccacttggccatctctctgcacaccaactcccaggaccagtttctgctgaaacagctt gtctccaatgtcctcatcttctcctgcaccaacattgtgggtgtgtgcactcactaccca gctgaggtctcccagagacaggccttccaggagacccgggagtgtatccaggctcggctc cattcccagcgggagaaccagcaacaggagcgtctcctgctgtctgtccttccccgtcat gttgccatggagatgaaagcagacatcaacgccaagcaggaggatatgatgttccacaag atctacatccagaagcatgacaatgtgagcatcctgtttgctgacatcgagggcttcacc agcctggcttcccagtgtactgcccaagaactggtcatgaccctcaatgagctcttcgcc cgctttgacaagttggctgcggagaatcactgtttacggattaagatcctcggggattgt tactactgcgtctcggggctgcctgaagccagagccgaccatgcccactgctgcgtggag atgggaatggacatgatcgaggccatctcgttggtccgggaggtgacaggggtgaacgtg aacatgcgcgtgggaattcacagcgggagagtacactgcggtgtccttggtctcagaaag tggcaattcgacgtgtggtctaacgatgtcactctggccaaccacatggaagctggtggc aaggcgggccgcatccacatcaccaaggccacactcaactacctgaatggggactatgag gtggaaccaggctgtggtggcgatcgcaatgcctacctcaaggagcacagcattgagacc ttcctcatcctgagctgtacccagaagcggaaagaagagaaggccatgatcgccaagatg aaccgccagagaaccaactccatcggacacaatccgcctcactggggagccgagcgcccc ttctacaaccacttgggcggcaaccaggtgtcaaaggagatgaagaggatgggctttgag gaccccaaggacaagaatgcccaggaaagtgcgaacccagaggatgaagtggacgagttt ctgggtcgggccatcgatgccaggagcatcgacagactgcgatctgaacacgtccgcaag ttcctcctgaccttcagggagcccgacttagagaagaagtactccaagcaggtggatgac cgatttggtgcctatgtggcctgcgcctcgcttgttttcctcttcatctgctttgtccag atcaccattgtgccccactccctgttcatgctgagtttctacctgtcgtgtttcctgctg ctggccttggtggtgtttgtgtctgtgatctatgcctgtgtgaagcttttccccactccc ctgcagacactctccaggaagatagtgcgatccaagaagaacagcaccctggtcggggta ttcaccatcaccctggtgttcctctcggcttttgtcaacatgttcatgtgcaactctaag aacctggtgggctgcctggcagaggagcacaacatcacggtgaaccaggtcaacgcatgt catgtgatggagtcggccttcaactacagcctgggcgacgagcagggcttctgtggcagc ccccagcccaactgcaacttcccagagtacttcacctacagcgtgctgctcagcctgctg gcctgctccgtgttcctgcagatcagctgcattggaaagctggtgctcatgctggccatt gagttcatctatgtgctcatcgtggaggtgcccggcgtcacactcttcgacaacgctgac cttctggtcaccgccaatgccatagacttcagcaacaacgggacctcccagtgccctgag catgcaaccaaggtggcgctgaaggtggtgacgcccatcatcatctctgtcttcgtgctg gctctgtatctgcatgcccagcaggtggagtccactgctcgccttgacttcctctggaaa ctgcaggccacagaagagaaggaggagatggaggagctgcaggcctacaatcggcgcctg ctgcacaacattctgcccaaggacgtggctgcccacttcctggcccgggaacggcgcaat gacgagctgtactaccaatcgtgcgagtgtgtggctgtcatgtttgcctccattgccaac ttctccgaattctatgtagagctagaggccaacaatgagggcgtcgagtgcctacggctg ctcaatgagatcatcgcagacttcgatgagatcatcagtgaggatcggttcaggcagctg gaaaagatcaagaccataggcagcacctacatggctgcctctggcctcaacgactccacc tatgacaaggcaggcaagacccacatcaaggctattgcagacttcgctatgaagctgatg gaccaaatgaagtacatcaatgagcactccttcaacaacttccagatgaagattgggctc aacattggacctgtagtggctggagtcattggggctcgcaagcctcagtatgacatctgg ggcaatacagtgaatgtggccagccgtatggacagcactggggtgcctgaccgcatccag gttactacagatatgtaccaggtgctggccgccaacacataccagctggagtgccggggt gtggtcaaggtcaagggcaagggtgagatgatgacttacttcctcaatggagggcctccc ctcagttag

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