Mus musculus (house mouse): 319757
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Entry
319757 CDS
T01002
Symbol
Smo, E130215L21Rik, Smoh, bnb, smoothened
Name
(RefSeq) smoothened, frizzled class receptor
KO
K06226
smoothened
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04340
Hedgehog signaling pathway
mmu04360
Axon guidance
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05217
Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
319757 (Smo)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
319757 (Smo)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
319757 (Smo)
05205 Proteoglycans in cancer
319757 (Smo)
09162 Cancer: specific types
05217 Basal cell carcinoma
319757 (Smo)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
mmu04030
]
319757 (Smo)
G protein-coupled receptors [BR:
mmu04030
]
Frizzled / Smoothened family
319757 (Smo)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Frizzled
Fz
Dicty_CAR
Motif
Other DBs
NCBI-GeneID:
319757
NCBI-ProteinID:
NP_795970
MGI:
108075
Ensembl:
ENSMUSG00000001761
Vega:
OTTMUSG00000013446
UniProt:
P56726
Q4VBD5
Q8BJN8
Structure
PDB
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All DBs
Position
6:29735496..29761365
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AA seq
793 aa
AA seq
DB search
MAAGRPVRGPELAPRRLLQLLLLVLLGGPGRGAALSGNVTGPGPHSASGSSRRDVPVTSP
PPPLLSHCGRAAHCEPLRYNVCLGSALPYGATTTLLAGDSDSQEEAHGKLVLWSGLRNAP
RCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDHFPE
GCPNEVQNIKFNSSGQCEAPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAA
FGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCR
ADGTMRFGEPTSSETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGK
TSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGG
YFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFN
QAEWERSFRDYVLCQANVTIGLPTKKPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWV
WTKATLLIWRRTWCRLTGHSDDEPKRIKKSKMIAKAFSKRRELLQNPGQELSFSMHTVSH
DGPVAGLAFDLNEPSADVSSAWAQHVTKMVARRGAILPQDVSVTPVATPVPPEEQANMWL
VEAEISPELEKRLGRKKKRRKRKKEVCPLRPAPELHHSAPVPATSAVPRLPQLPRQKCLV
AANAWGTGESCRQGAWTLVSNPFCPEPSPHQDPFLPGASAPRVWAQGRLQGLGSIHSRTN
LMEAEILDADSDF
NT seq
2382 nt
NT seq
+upstream
nt +downstream
nt
atggccgctggccgccccgtgcgtgggcccgagctggcgccccggaggctgctgcagttg
ctgctgctggtactgctggggggcccgggccggggggcggccttgagcgggaacgtgacc
gggcctgggcctcacagcgccagcgggagctcgaggagggacgtgccggtgaccagccct
ccgccgccgctgctgagccactgcggccgggccgcccactgcgagcctttgcgctacaac
gtgtgcctgggctcggcgctgccctacggagccaccaccacgctgctggctggggactcg
gactcgcaggaggaagcgcacggcaagctcgtgctctggtccggcctccggaatgccccc
cgctgctgggcagtgatccagcccctgctgtgtgctgtctacatgcccaagtgtgagaat
gaccgagtggagttgcccagccgtaccctctgccaggccacccgaggcccctgtgccatt
gtggagcgggagcgagggtggcctgactttctgcgttgcacaccggaccacttccctgaa
ggctgcccaaacgaggtacaaaacatcaagttcaacagctcaggccaatgtgaagcaccc
ttggtgcgaacagacaaccccaagagctggtatgaggacgtggagggctgtgggattcag
tgtcagaacccgctgttcaccgaggccgagcaccaggacatgcacagctacatcgcagcc
ttcggggcggtcactggtctctgcacgctcttcacactggccacctttgtggctgactgg
cggaactccaatcgctaccctgcggttattctcttctatgtcaatgcgtgtttcttcgtg
ggcagcattggctggctggcccagttcatggatggtgcccgccgagagattgtttgccga
gcagatggcaccatgagatttggggagcccacctccagtgagaccctgtcctgtgtcatc
atctttgtcattgtgtactatgccttgatggctggagtagtctggttcgtggtcctcacc
tatgcctggcacacctccttcaaagccctgggcaccacctaccagcctctctcgggcaag
acatcctatttccacctgctcacgtggtcactcccctttgtcctcacggtggcaatcctg
gctgtggctcaggtagatggagactccgtgagtggcatctgttttgtaggctacaagaac
tatcggtaccgtgctggctttgtcctggccccaattggcctggtgcttattgtgggaggc
tacttcctcatcagaggggtcatgactctgttctccatcaagagcaaccaccctgggctt
ctgagtgagaaggcagccagcaagatcaacgagaccatgctgcgcctgggcatttttggc
ttcctggcctttggctttgtgctcatcaccttcagctgccacttctatgacttcttcaac
caggctgagtgggagcgtagcttccgggactatgtgctatgccaagccaacgtgaccatc
gggctgcctaccaagaagcccattcctgactgtgagatcaagaatcggcccagcctcctg
gtggagaagatcaatctatttgccatgtttggcactggcattgccatgagcacctgggtc
tggaccaaggccaccctgctcatctggaggcgcacctggtgcaggttgactgggcacagt
gatgatgagcccaagagaatcaagaagagcaagatgatcgccaaggccttctctaagcgg
cgtgagctgctgcagaacccgggccaggagctctccttcagcatgcacactgtctcccat
gatggacctgttgcgggtttggcttttgacctcaatgaaccctcagctgacgtctcctct
gcctgggctcagcatgtcaccaagatggtggctcggagaggagccatattgccccaggat
gtgtccgttacccctgtggcaactccagtgccaccagaagaacaagccaacatgtggctg
gttgaggcagagatctccccagagttagagaagcgtttgggccggaagaaaaagcggagg
aagaggaagaaggaggtgtgccccttgaggccagcccctgagcttcaccactctgcccct
gttcctgccaccagtgcagttcctcggctgcctcagctgcctcggcagaagtgcctggta
gctgcaaacgcctggggaacaggggagtcctgccgacagggagcctggactctagtctcc
aaccccttctgcccagagcctagtccccatcaagatccatttctccctggtgcctcagcc
ccccgggtctgggctcagggccgcctccaggggctgggatccattcattcccgcactaac
ctaatggaggctgagatcttggatgcagactcggacttctga
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