Mus musculus (house mouse): 76088
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Entry
76088 CDS
T01002
Symbol
Dock8, 1200017A24Rik, 5830472H07Rik, A130095G14Rik
Name
(RefSeq) dedicator of cytokinesis 8
KO
K21852
dedicator of cytokinesis protein 6/7/8
Organism
mmu
Mus musculus (house mouse)
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
76088 (Dock8)
Membrane trafficking [BR:
mmu04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
76088 (Dock8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DHR-2_Lobe_A
DOCK-C2
DOCK_C-D_N
DHR-2_Lobe_C
DHR-2_Lobe_B
Motif
Other DBs
NCBI-GeneID:
76088
NCBI-ProteinID:
NP_083061
MGI:
1921396
Ensembl:
ENSMUSG00000052085
UniProt:
Q8C147
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:24976753..25179796
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AA seq
2100 aa
AA seq
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MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSISTSGFPSLQLPQLYEPVE
PVDFEGLVMTHLNSLDAELAQELGDLTDDDLHVAFTPKECRTLQHSLPEEGVELDPHVRD
CVQTYIREWLIVNRKNQGSSEFCSFKKTGSRRDFQKTLQKQTFESETLECSEPDTQTGPR
HPLNVLCDVSGKGPLTSCDFDLRSLQPDERLENLLQLVSAEDFEKEKEEARKTNRPAELF
ALYPPVDEEDAVEIRPVPECPKEHLGNRILVKVLTLKFEIEIEPLFASIALYDVKERKKI
SENFHCDLNSDQFKGFLRAHTPSIDPSSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIA
DCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNISTLER
ESTDVEPGVGRNSVGEKRSLSQSRRPSERTLSLEENGVGSNFKATTLATNIFFKQEGDRL
SDEDLFKFLADYKRSSSLQRRVKSIPGSLRLEISPAPDVMNCCLTPEMLPVKPFPENRTR
PHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFASKLASARNITIKIQFMCGEDPSNAMP
VIFGKSSGPEFLQEVYTAITYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQG
ASGESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHK
GVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVSFPIRVLDQKITESTLEHELKLSIIC
LNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRK
DQHGRNCLLASYVHYVFRLPELHRDTSKSGGPTTVVPDPRYHTYGRTSAAAVSSKLMQAR
VMSSSNPDLTGSHCAADEEVKNIMSSKIADRNCSRMSYYCSGNSDAPGSTAAPRPVSKKH
FHEELALQMVVSTGVVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDD
ITTIVNVVTSEIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCSQL
SAKLNILPTLISMRLEFLRILCSHEHYLNLNLLFMNTDTAPASPCPSISSQNSSSCSSFQ
DQKIASMFDLTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLCSHDLD
PRCRKPEVKVKIAALYLPLVGIILDALPQLYDFTDARSGRSRASGSYEEQDVANGINQNV
ALAIAGNHFNLKTSGAMLSSLPYKQYNMLNADTTRHLMICFLWIMKNADQSLIRKWIADL
PSMQLNRILDLLFICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMM
RRRIPGTDRFPGINENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILD
MQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEE
EMEQCADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMALASLV
GKAPDFNEEHLRRSLRTILAYSEEDTAMQTTPFPMQVEELLCNLNSILYDTVKMREFQED
PEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSML
EDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELF
STGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAFDNIINKDHKRMFGTYFRVGF
YGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFYGQCFGAEFVEVIKDSTPVDKTKLDPN
KAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQHRRNTVL
TTMHAFPYIKTRIRVSQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKMLQMVLQG
SVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQ
REYQQELKKNYNKLRDSLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS
NT seq
6303 nt
NT seq
+upstream
nt +downstream
nt
atggccacgctgccgagcgccgagcgccgcgccttcgcgctcaagatcaacaggtattca
tcgtcagaaataaggaagcagtttacgctcccacccaacctcggacagtaccatcggcac
agtatcagtacatctggtttcccctctcttcagctacctcagctttatgagcctgtcgag
ccagtggactttgaaggactcgtgatgacacacttaaacagcttggatgcagagctggcc
caggagctgggggacctcaccgatgacgacctgcatgtggccttcacacccaaagaatgt
aggactttgcagcactctctgccagaggaaggagttgaactggatcctcacgtcagagac
tgtgttcagacctatattcgagagtggctgattgtaaaccggaaaaaccaaggaagttca
gagttttgcagctttaaaaagacgggatctcgcagagattttcagaagacgcttcagaaa
cagacgtttgagtcagaaaccttggagtgcagtgaaccggacactcagacaggaccccgt
catcccttaaacgtgctgtgtgacgtgtctgggaagggccccctcacttcttgtgacttc
gacctccgcagcctgcagcctgatgagcggctggaaaacctgctccagcttgtgagcgct
gaggactttgagaaggagaaggaggaggcccgcaagaccaatcggccggctgagctcttt
gccctctatccgcccgtggatgaggaggatgctgtggaaatacgtccagtacctgaatgt
cctaaggaacatctgggcaacagaatattggtcaaggtgctgactctgaagtttgagatt
gaaattgaacctctgtttgccagtattgccctctatgacgttaaagaaaggaaaaagatc
tcagaaaatttccactgtgacctgaactccgaccagttcaaagggtttctgcgagctcac
acaccctcgattgacccatcgagtcaggctaggtctgccgtgttctctgtcacctaccca
tcttcagacatctacctggttgtcaagattgaaaaggtccttcagcaaggagagattgca
gactgtgcagaaccctacatgatcatcaaagaaagcgatggtggaaagagtaaagaaaag
gttgaaaaactaaaacttcaagctgaatccttctgccaacgtttggggaaataccggatg
cccttcgcctgggcccccattagcttagcaagcttcttcaacatctccacccttgaaagg
gagagcacagatgtggagcctggggttgggaggaactctgtgggtgagaagaggagcttg
tcccaatccaggaggccctctgagcgaaccctctccttggaggaaaatggagttggatcc
aacttcaaagccaccaccttggccaccaacatcttcttcaaacaggagggagatcgcctt
agtgatgaagacttgttcaagtttttagctgactacaagagatcttcatccctacagcga
agagtcaaatccatcccaggctcactgaggctggagatatccccagctcccgacgtgatg
aactgctgcctgacgcccgagatgctgccagtcaaaccttttcctgaaaatcggacgcgt
ccacacaaggagattttggaatttccgatccgggaggtgtacgtccctcacactgtgtac
agaaaccttctgtacgtatacccccagcgactgaacttcgctagcaagctagcatctgcc
cggaacatcacaataaagattcagtttatgtgcggagaagaccccagcaatgctatgccg
gtcatctttggcaagtccagtgggcctgaatttctgcaggaagtatatacagctattaca
taccataataagtctcctgacttttacgaagaagtgaaaattaagctccctgccaagctc
acagtgaatcatcacctcctcttcaccttctaccacatcagctgtcagcagaagcaaggg
gcctccggagaaagccttctggggtactcgtggctgccgattctgttaaacgaacgtctt
caaaccggatcctactgtctgcctgttgccttggaaaaactaccacccaactactccata
cattctgctgagaaagtccctttacagaatcctcccattaagtgggccgagggccataag
ggggtatttaatattgaagtgcaagctgtttcttccgtccacacccaggataaccacctg
gagaagttcttcaccctttgccactccctggagagccaggtgagcttccctatccgtgtg
ctggaccagaagatcaccgagagcacgctggagcacgagctgaaactcagcatcatctgc
ctcaactcctcccgcctggagcccctcgtgctcttcctccacctggtgcttgacaagctg
ttccagctttccgtgcagcccatggtcattgctggccaaacagcaaacttctcccagttt
gccttcgagtctgtggtggccattgccaatagcctgcacaacagcaaggacctgaggaag
gaccagcacgggaggaactgccttctggcctcctacgtgcactacgtgttccggctgccg
gaactgcacagggatacatccaagtcaggtggccccaccaccgtagtccccgacccccga
taccacacatatggacgcacatctgccgctgcagtgagttcaaagctgatgcaggcccgt
gtgatgagcagcagcaacccagacctgactgggtcacactgtgcagccgatgaggaagtt
aagaacatcatgtcttcaaagattgccgatcgcaactgcagccggatgtcttactattgc
tctggcaatagtgatgcgccaggttcaactgcagccccaagaccagtcagcaaaaagcat
ttccatgaggagcttgccctgcagatggtggtcagcactggagtagtgagagaaacggtc
ttcaagtacgcctggttcttctttgagcttctggtgaaaagcatggcacagtatgtccat
aacctggataaacgggacagttttcggaggactcgtttttctgaccgcttcaaagatgac
ataactaccattgttaatgtggtcacctcggagatagcagcccttttagtgaaacctcag
aaggaaagcgagcaggcagaaaagatcaacatcagccttgccttcttcctgtatgacctc
ctgtcaatcatggacagaggcttcgtgttcaacctcatcaagcattactgcagccagctg
tcagccaagctgaatatccttccaacgctcatctccatgcggctggaattcctgaggatc
ctctgcagccatgagcactacctcaacttgaacctcctcttcatgaataccgacaccgca
ccagcatctccctgcccctccatatcctcccagaactcgagttcctgctccagtttccag
gaccaaaagattgccagcatgttcgatctgaccccggagtaccggcagcagcacttcctt
acagggctgctcttcacggagctggctgttgccctggatgctgagggggatggaattagc
agagtacagagaaaagccgtgagtgccatccacagccttctgtgttctcacgacctggat
ccacggtgtcgcaaaccggaagtgaaagtcaaaatcgccgccctttacctgccgttggtc
ggcatcattctggacgctctgccacagctctatgactttacagatgctcgcagtggaagg
agtcgtgccagtggctcgtatgaagaacaagatgtggccaacggaatcaaccagaatgtg
gccctggccatagcggggaatcactttaatttgaagaccagtggagcaatgctgtcttcc
ttgccctataagcagtacaacatgctgaatgcagacaccacccgccacctcatgatttgc
ttcctgtggatcatgaaaaatgctgatcagagcctcatcaggaagtggatcgctgacctg
ccttccatgcagctcaataggattctggacctgctgttcatctgtgtctcctgctttgaa
tacaagggaaagcagagttctgacaaagtcagtaaccaggtcctgcagaagtcaagagac
gtcaaggccaagctggaagaggccctgctccgtggggaaggagcccgtggggagatgatg
cgccgtcgcattccagggactgaccggtttccaggcataaatgaaaatctgagatggagg
aaagagcagacacagtggcggcaggctaatgagaagctggacaaaacaaaggcagagtta
gatcaagaagccttgatcagtggcaacctggctacagaagctaatttgatcatcctggat
atgcaggagaacatcatccaggcaagctccgccctggactgtaaagacagcctgctggga
ggtgtcctccgggtcctggtgaattctctgagctgtgaccagagcaccacctacctgact
cactgtttcgcaaccctccgagccctcatcgccaagtttggagacctgctgttcgaggag
gagatggagcagtgtgctgacctgtgtcagcgggtgctacatcactgcagcagcagcatg
gacgtcacacggagccaagcctgcgccaccctctacctcctcatgcggttcagcttcgga
gccaccagtaactttgcaagggtaaagatgcaagtgaccatggcactggcatccctggta
ggcaaagcaccagacttcaacgaagagcacctgagaaggtccttaaggacaattttggcc
tattcagaagaggacacggccatgcagacaactccttttcccatgcaggtggaggaactt
ctctgcaatctgaacagcattctgtacgacacagtgaagatgagggaattccaggaagac
cctgagatgcttatggacctcatgtacagaattgccaagagctaccaggcatcgcctgac
ctgcggctgacttggctccagaacatggcagagaaacacactaagaagaagtgcttcaca
gaggccgccatgtgcctggtgcatgcagccgccctggtggccgagtacctgagcatgctg
gaggaccacagctacctgccggtgggcagcgtcagctttcagaatatttcttccaatgtg
cttgaggagtctgcagtctctgatgacaccttgtcacctgatgaggacggcgtatgctct
ggtcggtacttcactgagagtggcctggtgggcctcctggagcaggctgcggagctcttc
agcacgggaggcttgtacgagacggttaatgaagtctacaagctggtcatccctatcctg
gaggcacacagagatttccggaagctgacctccactcacgacaagctgcagaaggccttc
gataacatcatcaacaaggaccataagaggatgtttgggacctacttccgagttggtttc
tacggatcccgatttggggatttggatgagcaggagttcgtgtacaaggaacccgcaatc
acgaagctcccggagatctcacatagactagagggattttatggccagtgtttcggtgca
gagtttgtggaagtgataaaagactctactccagtggacaaaaccaagttggatcctaac
aaggcctacattcagatcacttttgtggagccttactttgatgaatatgagatgaaagac
cgggtgacctacttcgagaagaatttcaacctccggaggttcatgtacaccacccccttc
accctggaggggagaccccggggcgagcttcatgagcaacaccgcagaaacaccgtgctc
accaccatgcacgccttcccctacatcaagaccaggatccgagtcagccagaaagaggag
ttcgttttgactccgattgaggttgccattgaagatatgaagaagaagaccctgcagtta
gccgtggccactcaccaggagccccctgatgcaaagatgctgcaaatggtactgcagggc
tctgtaggagccactgtaaatcagggaccactggaggtggcccaagtgttcttggctgaa
attccagctgacccaaagctctaccgacatcacaacaagctgaggttgtgcttcaaggag
ttcataatgcgatgcggagaggccgtggagaagaacaggcgactcatcaccgcagagcag
cgggagtaccagcaggagctgaagaagaactacaacaagctgagagacagcctcaggccc
atgattgagcggaaaatcccagagctctacaagcccatattcagagttgacagtcagaag
agggactctttccacagatctagtttcaggaaatgtgaaacccagttgtcacagggcagc
tga
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integrated database retrieval system
