Myotis myotis (greater mouse-eared bat): 118667106 Help Entry 118667106         CDS       T07220                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4   KO K10160   toll-like receptor 4 Organism mmyo  Myotis myotis (greater mouse-eared bat) Pathway mmyo04064   NF-kappa B signaling pathway mmyo04066   HIF-1 signaling pathway mmyo04145   Phagosome mmyo04151   PI3K-Akt signaling pathway mmyo04217   Necroptosis mmyo04613   Neutrophil extracellular trap formation mmyo04620   Toll-like receptor signaling pathway mmyo04621   NOD-like receptor signaling pathway mmyo04936   Alcoholic liver disease mmyo05132   Salmonella infection mmyo05133   Pertussis mmyo05134   Legionellosis mmyo05135   Yersinia infection mmyo05140   Leishmaniasis mmyo05142   Chagas disease mmyo05144   Malaria mmyo05145   Toxoplasmosis mmyo05146   Amoebiasis mmyo05152   Tuberculosis mmyo05161   Hepatitis B mmyo05162   Measles mmyo05164   Influenza A mmyo05170   Human immunodeficiency virus 1 infection mmyo05171   Coronavirus disease - COVID-19 mmyo05205   Proteoglycans in cancer mmyo05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mmyo05321   Inflammatory bowel disease mmyo05323   Rheumatoid arthritis mmyo05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mmyo00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     118667106 (TLR4)    04066 HIF-1 signaling pathway     118667106 (TLR4)    04151 PI3K-Akt signaling pathway     118667106 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     118667106 (TLR4)   09143 Cell growth and death    04217 Necroptosis     118667106 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     118667106 (TLR4)    04620 Toll-like receptor signaling pathway     118667106 (TLR4)    04621 NOD-like receptor signaling pathway     118667106 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     118667106 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     118667106 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     118667106 (TLR4)    05161 Hepatitis B     118667106 (TLR4)    05171 Coronavirus disease - COVID-19     118667106 (TLR4)    05164 Influenza A     118667106 (TLR4)    05162 Measles     118667106 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     118667106 (TLR4)    05135 Yersinia infection     118667106 (TLR4)    05133 Pertussis     118667106 (TLR4)    05134 Legionellosis     118667106 (TLR4)    05152 Tuberculosis     118667106 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     118667106 (TLR4)    05144 Malaria     118667106 (TLR4)    05145 Toxoplasmosis     118667106 (TLR4)    05140 Leishmaniasis     118667106 (TLR4)    05142 Chagas disease     118667106 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     118667106 (TLR4)    05321 Inflammatory bowel disease     118667106 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     118667106 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     118667106 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mmyo04131]     118667106 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:mmyo04054]     118667106 (TLR4)    04090 CD molecules [BR:mmyo04090]     118667106 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:mmyo00536]     118667106 (TLR4) Membrane trafficking [BR:mmyo04131]  Endocytosis   Phagocytosis    Toll-like receptors     118667106 (TLR4) Pattern recognition receptors [BR:mmyo04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    118667106 (TLR4) CD molecules [BR:mmyo04090]  Proteins   118667106 (TLR4) Glycosaminoglycan binding proteins [BR:mmyo00536]  Hyaluronan   Cell surface receptors    118667106 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 LRR_5 TIR_2 LRR_9 LRR_6 ThsB_TIR Motif Other DBs NCBI-GeneID:  118667106 NCBI-ProteinID:  XP_036185722 LinkDB All DBs Position Unknown AA seq 839 aa AA seqDB search MWPTRLAGALLPAMAFLSCLRPESWDPCVQVVPNVTYQCMELNLYKIPDNIPTSVKNLDL SFNPLRHLGSHSFSNFSELQVLDLSRCEIQKIEDDAYQGLKHLSILILTGNPIQSLAPGA FSGLPSLQTLVAVETNLASLEDFPIRHLKTLKELNVAHNLIDSFKLPDYFSNLPNLEHLD LSNNKIRNIYHEDLQVLHQMPSFKLSLDLSLNPLDFIQSGAFEKIKLHELTLRSNFDSAE VMKTCIQGLASLKINRLILGEFKNERTLVNFNKSALEGLCNLTIEEFRIAHFDEFPGDDL GFLNCLEDASTISLVSLYLGEPKIFLKGFKWQYLHLSKCTFEHFPALELTFLKQFVFTAN KGITTFTEVNLPNLEFLDLSRNSMSFKSCCSRRDFGTTRLKHLDLSFNNIIIMTSNFLDL EQLEHLDFQHSTLKQASDFSVFLSLKNLLYLDISHTNTKIVFLGIFDGLISLQVLKMAGN SFQDALLPNIFRDLTQLTVLDLSQCQLERVSQEAFGSLLRLQVLNMSHNHLLSLDMLPYK NLSLQVLDCSFNRIVAANGQELQHFPSNVTSLNLTRNNFACACEHMRFLQWVQDHRRILV GAEHMMCEKPLAMQGVPVLSFRNATCQMSKTIISVSVLSVLVVSVAAVLVYKFYFHLMLL AGCKKYGKGESTYDAFVIYSSHDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAAN IIQEGFHKSRKVIVVVSQHFIQSRWCLFEYEIAQTWQFLSSHAGIIFIVLKKVEKSLLRQ QVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKPWSPEGTEDAESSQDEATTST NT seq 2520 nt NT seq  +upstreamnt  +downstreamnt atgtggcccacccgcctggctggggcgctgctcccagccatggccttcctctcctgcctg agacccgagagctgggacccttgcgtgcaggtggttcctaacgttacttaccagtgcatg gagctgaatctctacaaaatccctgataacatccctacatcagtcaagaacctggacttg agctttaaccccctgaggcatttaggcagccacagcttctccaacttctcagaactgcag gtgctggatttatccaggtgtgaaattcagaagattgaagatgatgcatatcaaggccta aagcatctctccatcttgatattgacaggaaaccctatccagagtttagcccctggagcc ttttctggactgccaagtttacagacactggtggctgtggagacaaacctagcatcgcta gaggacttccccatcagacatctgaaaaccttgaaggagcttaatgtggctcacaatcta attgattccttcaagttaccggactatttttctaacctgcctaacctggagcacttggat ctttccaataacaagatccgcaatatttaccatgaagacctgcaggttttacatcaaatg ccctcattcaaactctccttagacctgtccctcaaccctttagactttattcaatcaggt gcctttgaaaaaattaagctccatgaactgactttgagaagtaattttgatagtgcagag gtcatgaaaacgtgtattcaaggtctggccagtttaaagatcaatcggttgattttggga gaatttaaaaatgaaagaaccttagtaaacttcaacaaatctgccctggagggtctgtgc aatttgaccattgaagaattccggatagcacacttcgatgagtttccaggggatgatctt ggctttttaaattgtttggaagatgcttctacaatatctcttgtgagtctatatttaggc gaaccaaaaatctttctaaaaggtttcaaatggcaatacttacatttgtctaaatgtaca tttgaacattttcctgcattggagcttacctttctcaagcagtttgttttcactgccaac aaaggtattaccactttcactgaagttaatctaccaaaccttgagtttctagatctcagt agaaatagcatgagtttcaagtcttgctgctctcgccgtgattttgggacaacccgactg aaacacttagatctgagcttcaataatattattatcatgacttcaaacttcttggactta gagcaactagaacatctggatttccagcattccactctgaaacaggccagtgatttttca gtattcctctcactcaaaaatctcctttaccttgatatttctcacactaacaccaagatt gtcttcctgggcatctttgatggcttgatcagcctccaagtcttgaaaatggctggcaat tcttttcaggatgcactcctcccaaatatcttcagagacctgactcagttgactgtcctg gacctctctcagtgtcaactggaacgggtgtcccaggaggcatttggctcactccttaga ctccaggtgctaaatatgagtcacaaccacctcttgtccttggatatgcttccttataaa aatctctctctccaggttctagactgcagttttaaccgtatagtggccgccaatgggcag gaactacaacattttccaagcaatgtaacttccttaaatctgacccggaataactttgct tgtgcttgtgaacacatgcgtttcctgcagtgggtccaagatcacaggcgcatcttggtg ggagctgaacatatgatgtgtgagaaacctttagctatgcagggcgtgcctgtgctcagt tttagaaatgccacctgccagatgagcaaaactatcattagtgtgtcagttctctcagta ctcgtggtctctgtagccgcagttctggtctacaagttctatttccacctgatgcttctg gctggctgcaaaaaatacggcaaaggggaaagcacctacgatgcctttgtcatctactcc agccatgatgaggactgggtgaggaatgagttggtgaagaacttggaggagggggtaccc ccctttcagctctgtcttcactacagagactttatccctggggtggccattgctgccaac atcatccaggaaggtttccacaagagccggaaggtaattgtggtggtgtcccagcacttt atccagagccgatggtgcctctttgagtacgagatcgcccagacctggcagttcctgagc agtcatgcgggcatcatcttcatcgtcctgaagaaggtggaaaagtccctgctcaggcag caggtggaactgtatcgccttctcagcaggaacacttacctagagtgggaggacagtgtc ctgggccggcacatcttctggcgacgactgagaaaagccttgctggatggtaagccatgg agtccagaaggaacagaggatgcagaaagcagccaggatgaagcaacgacctccacctga

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