Myotis myotis (greater mouse-eared bat): 118674511 Help Entry 118674511         CDS       T07220                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism mmyo  Myotis myotis (greater mouse-eared bat) Pathway mmyo04020   Calcium signaling pathway mmyo04371   Apelin signaling pathway mmyo04713   Circadian entrainment mmyo04921   Oxytocin signaling pathway mmyo04970   Salivary secretion mmyo05010   Alzheimer disease mmyo05012   Parkinson disease mmyo05020   Prion disease mmyo05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:mmyo00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     118674511 (RYR3)    04020 Calcium signaling pathway     118674511 (RYR3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     118674511 (RYR3)   09154 Digestive system    04970 Salivary secretion     118674511 (RYR3)   09159 Environmental adaptation    04713 Circadian entrainment     118674511 (RYR3)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     118674511 (RYR3)    05012 Parkinson disease     118674511 (RYR3)    05020 Prion disease     118674511 (RYR3)    05022 Pathways of neurodegeneration - multiple diseases     118674511 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:mmyo04040]     118674511 (RYR3) Ion channels [BR:mmyo04040]  Voltage-gated cation channels   Ryanodine receptor    118674511 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_5 Motif Other DBs NCBI-GeneID:  118674511 NCBI-ProteinID:  XP_036202331 LinkDB All DBs Position Unknown AA seq 4856 aa AA seqDB search MEELEDEVVLQCIANIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCVCNFVLEQS LSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAILLRHSFSGMYLTCLTTSRSQTDKL AFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNANIQV DASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTDQNDSQHRRIFYEA GGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLLLQDRVKSDT KSTAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHVASGLWVTYKAQDAKT SRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQFVSGNNRTAAPVT LPIEEVLQTLRDLIAYFQPPEEEMQHEDKQNKLRSLKNRQNLFKEEGMLALVLTCIDRLN IYNSVAHFAGIAREESGLAWKEILNLLYKLLAALIRGNRNNCAQFSNNLDWLISKLDRLE SSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHKVLDVLCSLCLCNGVAVR ANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFL TPEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVASINQ HLLKSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDGLFFPVVSFSAGVKVRFLMGG RHGEFKFLPPSGYAPCYEALLPKEKMRLEPAKEYKRDSDGIRDLLGTTQFLSQASFTPCP IDTSQVVLPPQLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKRQHPCLVEFSKLPE TEKNYNLQMSTETLKTLLALGCHIAHVNPAAEEDLKKVKLSKNYIMSNGYKPAPLDLSDV KLLPSQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYALLDERTKKSN RDSLREAVRTFVGYGYNIEPSDQELADPAVEKVSIDKIRFFRVERSYAVRSGKWYFEFEV VTGGDMRVGWARPGCRPDVELGADDQAFVFEGSRGQRWHQGSGYFGRTWQPGDVVGCMIN LDDASMIFTLNGELLITNKGSELAFADYEIENGFVPICSLGLSQIGRMNLGMDASTFKFY TMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPQIEVMRIDSTMDSPPCLKVTH KTFGTQNSDASMIYLRLSMPIECHSSFTHSPCLDSDAFQKRKQMQELLSQTTTQCYYAIR IFAGQDPSCVWVGWVTPDYHFYSEKFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGG DIVATSQRSSRSNVDLEIGCLVDLAMGMLSFSANGKELGTCYQVEPNTKVFPAVFLQPTS TSLFQFELGKLKTALPLSAAIFKSEEKNPAPQCPPRLDVQTIQPVLWSRMPSSFLKVETE RVSERHGWVVQCPEPLQMMALHIPEENRCVDILELCEQEDLMQFHYHTLRLYSAVCALGN SRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLANAKERKLMMKNEYIIPI NSTTRKIRLYPDKSKRHELPGVGLRTCLKPGFKFSTPCVVMTSEEHQKQSPEIPLDILKT KALSMLTEAVQGSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMGVFDDDDVRQILLLIDPS VFGEHSGETEEGAEKEEVTQVEEKAVEAGEKASKEAPVKGLLQTRLPESVKLQMCELLSY LCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALNMSAALTARKTKEFRSPPQEQ INMLLNFQLGENCPCPDEIREELYDFHEDLLTHCGVPLEGEEEEEEDSSWTGKLRALLQK VKGPPKPEQHQPAVEEERCPTTLKELISQTMIRWAQEDQIQDADLIRMMFNLLRRQYDSI GELLQALRKTYTISQASVSDTINLLAALGQIRCLLSVRMGKEEELLMINGLGDIMNNKVF YQHPNLMRVLGMHETVMEVMVNVLGAEKSQIAFPKMVASCCRFLCYFCRISRQNQKAMFE HLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLEKVVTYLAGCGLQS CPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALR GEGGNGLLAAMQGAIKIAENPALDLPSQGYKREVSTEDSEDEEEIVHMGNAIMSFYSALI DLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPSLNKDGSVSEPDM AASFCPDHKASMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALAL NRYICSAVLPLLTRCAPLFAGTEHYTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAI CNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTSHYEQCWKYYCLPSGWGSYGLAVEE ELHLTEKLFWGIFDSLSHKKYDPDLFRMALPCLSAIAGALPPDYLDTRISATLEKQISVD ADGNFDPKPINTMNFSLPEKLEYIVTKYAEHSHDKWACDKSQSGWKYGISLDENMKTHPL IRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEAEALVQQRENEKLRSMSQASQG NSYSPAPLDLCNVALSRELQGMVEVIAENYHNIWAKKKKLELESKGGGSHPLLVPYDTLT AKEKSRDREKAQDLFKFLQVNGIVVSRGMKDMELDASSMEKRFAYKFLKKILKYVDSAQE FIAHLEAIVISGKTERSPHDQEIKFFAKVLLPLVDQYFTNHRLYFLSSPLKPLSSSGYAS HKEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTVMKSGSELVKAGL RAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTAALLPILTSIFEHVAQHQF GVDLLLGDVQISCYHILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPTLNR YNPLSVFNTKTPRERSILGVPDTVEEMCPDIPPLERLMKEIHHLAESGARYTEMPHVIEV ILPMLCNYLSYWWEQGPEHLPPSTGPWCTKVTSEHLSVILGNILKIINNNLGIDEASWMK RIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAVKTVQEEEQLKADSKGDTQEAELLILD EFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEVFILWCKSHNFKREEQ NFVIQNEINNLAFLTGDSKSKMSKAMQVKSGGQDQERKKTKRRGDLYSIQTSLIVAALKK MLPIGLNMCTPGDQELISLAKSRYSCRDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYK DVLKSEEPSNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRM APLYNLPRHRSINLFLHGYQRFWIETEEYSFEERLVQDLAKSPRAEEEEEAEAEKQPDPL HQIVLHFSRNALTERSKLEDDPLYTSYSSMMAKSCQDGEDEEEEEDKEKTFEEKEMEKQK TLYQQARLHERGAAEMVLQMISASKGERSPMVVETLKLGIAILNGGNAGVQQKMLDYLKE KKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQNDEFTR DLFRFLQLLCEGHNNDFQNFLRTQMGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDI IDESGQHNFSKALVVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMK LSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFF DMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEIDFLLSCAEADENDM FNYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFEPYLGRIE IMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTI FEMQLASQISESDSNDRAEEEEEEDEDSSYTLEIEGEEEDDKSFESVSAFAMACASVKRN VANFLKRVTLKNLRKQYRKVKKMTVKELVKVFFSFFWMLFVGLFRLFFTILGGIFQILWN TVFGGGLVEGAKNIRVIKILGDMPDPTQFGIHDDVLEAERAEVTETGITTELVHFLKGEK GDADIMSDLFGFHSKKEGGSKHGPEVGLGDLSEIIGKDEPPTLESTVRKKRKVQAAEMKA AHDSEGKVEPEKADMEDGEKEETAGEQAKVLWAEATKKKKRRRGQKVEKPEAFMANFFKG LEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEEAEDVVNLWHSFSD DEEEEAMVFFVLQESTGYMAPALRALAVIHTIISLVCVVGYYCLKVPLVVFKREKEIARK LEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAEL LGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHIWKLGVVFTDNSFLYLAWYTTMSIL GHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRK FYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFF FFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQ EHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14571 nt NT seq  +upstreamnt  +downstreamnt atggaggaattggaagacgaagtggttctccaatgcatcgccaacattcacaaggagcag aggaagttctgcctggcagccgagggccttggcaatcgcctgtgcttcttggaacccact tcagaagccaagtatgttcctccagatctctgtgtctgcaattttgtgctggagcagtcc ctctcggtgagagccctgcaggaaatgcttgccaacacaggtgaaaatggtggtgaaggg gcagcacaaggaggtggccacaggaccctgctctatggccacgcgattctcctgcggcac tcttttagcggaatgtatctaacatgtttgactacatcaagatcccagacagataaactt gcctttgatgtaggcctacgggaacatgccacaggagaagcctgttggtggaccatacat cccgcttccaaacagaggtccgagggagaaaaagttcgaattggagatgacctcatcctc gtcagcgtgtcctctgaaagataccttcatctctccatatccaatgctaacatacaagtg gatgcctccttcatgcaaacactctggaatgtacatcctacgtgctcaggaagcagcatc gaagaaggatacctccttggtgggcatgtagtacgtcttttccacggtcatgatgagtgt ttgacgataccatctacggaccagaatgattcccagcacaggaggatattctatgaagca gggggagctgggacacgagccagatctctgtggagagtggaacccctacggataagctgg agtggcagtaacatcagatggggccaggctttccggctgcggcatctcaccacaggccac tacctggccttgactgaggaccaaggccttctactgcaagaccgggtaaagtcagacacc aagtccacagccttctctttcagggcatcaaaggaaatcaaggagaaattagattccagt cacaaaagagatatagaaggcatgggagttccagaaatcaagtatggagattctgtctgc tttgtccagcacgtagccagtggtctgtgggtgacctacaaagcacaagatgccaagaca tcccgccttggacccctgaaaagaaaggttatcctccaccaggaaggccacatggatgac ggattaacactgcagagatgccagcgcgaggagtcccaggctgctcgtatcatcaggaac acaacagccttattcagccagtttgtaagtggaaacaatcgcacagctgcccccgtgacg ctgccgatagaagaggtcctgcaaaccttacgggacttgatcgcctatttccagccccca gaggaggagatgcagcatgaagacaagcagaacaagcttcgctcgctcaaaaacagacag aatcttttcaaggaagagggaatgttggccctggtgttaacgtgcattgatcgcttaaat atctacaacagcgtagcacactttgcagggattgcaagagaggagagtggcctggcctgg aaagaaattctgaaccttctgtacaaattgctggctgccctcatccgtggaaacagaaac aactgtgctcaattctccaataaccttgattggctcatcagcaaattagacagactagaa tcttcctcaggcatcttggaagtgttacactgcatcctgattgaaagcccagaagcctta aacctgatagcagagggccacatcaagtccatcatctccctcctggataaacacggacgg aaccacaaggttctagatgtcctgtgctccctctgtctctgcaatggggtggctgtgaga gccaaccagaatctgatctgtgacaacttgctgccccggagaaacctgctcctgcagaca cggctgattaacgacgtgacgagtattcggccaaacatcttcctgggagtcgctgagggc tcagcacagtacaagaagtggtacttcgagctcattattgaccaggtggaccccttccta acaccagagcccacacacctgcgggtgggctgggcctcgtcctcgggctacgctccgtac cccggaggtggagaaggatggggaggcaatggtgttggtgatgacctgtactcctatggc tttgatggacttcacctttggtcaggccgcattcccagagctgtggcctccatcaaccag catctcctgaaatcggacgacgtggtgagctgttgcctggaccttggggtgcccagcatc tctttccgcatcaacgggcagcctgtgcaggggatgtttgagaacttcaacaccgatggg ctcttcttccctgtggtgagcttttcagcaggtgtcaaagtacgtttcctgatgggtgga cgtcatggggaatttaagttcctgcctccctctggctatgccccttgctatgaagcctta cttcccaaagaaaagatgagactggagcctgccaaagaatataaacgtgacagcgacggc attagagatctgctgggaaccacccagttcctctcccaggcttctttcactccgtgcccc atagacaccagccaggtggttttgccgcctcagctagagaagatccgagacagactggct gaaaatatccacgagctttggggaatgaacaaaatagagcttggctggacttttggcaag atacgggatgacaataaaagacaacacccctgccttgtggagttttcaaagctgcctgaa actgagaagaattataacctgcaaatgtcaactgaaaccttaaaaaccctcctggcctta gggtgtcacatcgctcatgttaacccagctgctgaagaagatctcaagaaggtcaaactg tccaaaaactacatcatgtctaatggctataaaccagcccctttggatttgtctgatgtg aagctattaccttctcaggaaatcttagtggataagcttgcagaaaatgcacataatgtc tgggcaaaagacagaataaaacaaggatggacctatggcattcaacaggatttgaagaac aaacgaaatccccgcctggtgccatacgcattactggatgagcgtaccaagaagtcaaac agggacagccttcgcgaagctgtccggacattcgttggctatggctataacatcgagcca tcagaccaggaactagctgacccagctgtggagaaagtcagcatagacaagatccggttc ttccgggtagagcggtcttatgcagtgagatctggaaagtggtattttgagtttgaggtg gtgactggaggagacatgcgtgtgggctgggcccgaccaggctgtcggcctgatgttgag ctgggcgctgatgaccaagcctttgtgtttgaaggcagcagggggcagcgttggcatcaa gggagtgggtattttggacgtacctggcagccaggagatgtggttggatgtatgattaac ctggatgatgcttcaatgatcttcacactgaatggggagctgctaatcaccaacaaaggc tcagaacttgccttcgcagattacgagattgagaatggctttgtgcccatctgctctctg gggctgtctcagatcggccgcatgaatctcgggatggatgccagtaccttcaagttttat accatgtgcggcctccaagagggctttgagccttttgctgtcaacatgaaccgagatgtt gcgatgtggttcagcaagcgcctcccaacgtttgtcaacgtgccgaaggatcatccccag atagaggtcatgaggatcgacagcaccatggacagccctccgtgcctcaaggtgacccac aagacatttggcacacagaatagcgatgccagcatgatctacctccgcctgagcatgccc atcgagtgccactcctccttcacccacagcccctgcctggacagtgatgctttccagaaa aggaaacagatgcaagaactactctctcaaacaacaacacagtgctactacgccatccgc atctttgccggacaagacccctcctgcgtctgggtcggatgggtgactccagactatcac ttctacagtgaaaagtttgacctgaataaaaactgtacggtgactgttactctgggggat gaaagaggccgggtccacgaaagtgtgaagcgcagcaactgctacatggtctggggtggg gacattgtggccacttcccaacgatcaagtcgcagcaacgtggacctggagatcggctgc ctcgtggatctggcaatgggcatgttgtccttctcggccaatgggaaagaacttggcacc tgttaccaggtggagcccaataccaaagtgttcccagcagtcttcctgcagcccacaagc acttctttgtttcagtttgaacttgggaagctgaagaccgcactgccactgtcagcagcc atatttaagagcgaggagaagaacccagccccgcagtgtccccctcggctggacgtgcag accatccagcccgtgctctggagccgcatgcccagcagcttcctgaaggtggaaacagag cgggtgagcgagcgccatggctgggtggtgcagtgcccggagcccctgcagatgatggcg ctccacatccctgaggagaacaggtgtgtggacatcctggagctctgtgagcaggaggac ctgatgcagttccattaccacacgctgagactctacagtgccgtgtgtgccctgggaaat agccgtgtagcctatgccctgtgcagccacgtggacctctcccagctcttctacgccatt gataacaagtacctccctggcctcctgcggtccggtttctatgacctgctcattagcatc catctggccaatgcgaaggagagaaagctgatgatgaagaatgagtacatcatccccatt aacagcaccaccaggaaaatccgcctgtacccagacaagtcgaagaggcatgagctgcct ggggtgggcctgagaacgtgcctgaagccaggcttcaagttctccaccccttgcgttgtc atgaccagtgaggagcaccagaagcagagccctgagattcccttggacattctgaagaca aaagccctgagcatgctgacagaggccgtgcagggcagtggggctcacatccgagacccc gttggggggtctgtggagttccagtttgtgccagtgctgaagctcattggaaccctgctg gtcatgggggtgtttgacgacgatgatgttcggcagattctcctcctgatcgacccatct gtgtttggggagcacagtggggagacagaagaaggagcagagaaggaggaagtgactcag gtggaggagaaggcagtggaggctggggaaaaggccagcaaggaggctccagtcaaaggc ttgttacagacacgattaccggagtccgtcaagctgcagatgtgcgagctcctcagctac ctctgtgactgtgagctgcagcaccgagtggaggccattgtggcatttggtgacatttat gtctccaagctccaggcgaatcagaagttccgctacaacgagctcatgcaggccctgaac atgtctgcggccctgactgccaggaagaccaaggagttccgctcacccccacaggagcag atcaacatgcttctgaactttcaactgggagagaactgcccctgcccagacgagatccgg gaggagctgtatgacttccacgaggaccttctcactcactgtggggttcccctggaggga gaggaagaggaggaggaggacagctcttggacaggcaaacttcgtgccttgttgcagaaa gtcaaaggccctcccaagccagaacagcatcagccggcagtggaagaagagagatgccct acaacactgaaggaactcatctcacagacgatgatccgctgggcccaggaggaccagatc caggatgcagacctaatccggatgatgttcaacctccttcggaggcagtacgacagcatt ggggagctgctgcaggccctgcggaagacctacaccatcagccaggcctccgtgagtgac accatcaacctgctggctgccctcggccagattcgctgcctcctcagcgtcaggatgggc aaggaagaggagctgctcatgatcaatgggctgggagacataatgaacaacaaggtgttt taccagcaccccaacctcatgcgcgtcctcggcatgcacgagacggtgatggaggtgatg gtgaacgtgctgggcgcagagaaatctcagatcgcttttccaaagatggtggctagctgt tgccgcttcctttgctatttctgtcgaattagccggcagaatcagaaggccatgtttgag cacctgagttacctgctggagaatagcagtgttggcctagcctccccgtcgatgagggga tccactccgctagatgtggccgcctcctccgtgatggacaacaacgagttagcactgggc ttagaggaaccagacctcgagaaggtggtgacttacttggcaggctgtggcctccagagc tgccccatgctgctggccaaaggataccctgacgtcggctggaaccccattgaaggggag cggtacctgtccttcctgaggtttgccgtcttcgtgaacagtgaaagtgtggaagaaaat gccagtgtcgtggtcaagctgctcatcagacgccccgagtgctttggccctgccctgcgg ggtgaaggaggaaatggtctgttggcagccatgcagggtgccattaagatcgctgagaac ccagccctcgacctcccctctcagggatacaagagagaagtcagcacagaagacagtgaa gatgaagaagagatcgtacacatgggcaatgcaattatgtcattttattcagctcttata gatctactgggccgctgtgctcctgaaatgcaccttatccagacaggaaaaggggaagcc atccggatcaggtcaatcctacgctcccttgttcccaccgaggacttggttgggatcatc agcatccccttgaaactgccctccctgaacaaagatgggtctgtcagcgagcccgatatg gctgccagcttctgccctgaccacaaggcctccatggtgctcttcttggaccgtgtctat ggtattaaggatcaaacttttctgctccacctgctagaggttggatttttacctgattta agagcctctgcctctctcgatacagtgtctctaagcaccacagaggctgcactggcgcta aataggtacatatgttctgctgtgctcccgctcctcacaaggtgtgcccctctctttgct ggaacggagcactacacctctttgatcgattcaacactgcagacaatatacaggctgtcc aagggacgttccctcaccaaagctcagagggacaccatagaagaatgtttgcttgccatt tgcaatcacctgaggccttccatgttacagcagctcctgcgacgccttgtttttgatgtg ccccagctcaatgaatactgcaaaatgcccctgaagctcctgacgagccactatgagcag tgctggaagtattactgcctgccctcggggtggggcagctatggcctggccgtggaggag gagctgcacctcacggagaagctcttctgggggatttttgactccctctcccacaagaag tatgacccagatcttttccgaatggccctgccttgtctcagtgctatcgccggggccttg ccacctgattacttagataccaggatctcagccacattggagaagcagatctcagtggat gcagacggcaactttgaccccaaaccgatcaacaccatgaatttctccttgcctgaaaaa ttggaatacatcgtcaccaagtatgctgagcattcacatgataagtgggcctgtgacaag agtcagagcgggtggaaatatggaatttccctggacgagaacatgaagacccatccactg ataaggcccttcaagacattgacggagaaggagaaggaaatttatcgctggccagccaga gagtccctgaaaactatgctggctgtgggctggactgtggagaggaccaaagaagcagaa gccctagttcaacaacgggaaaatgagaagcttcgaagcatgtcccaggccagccagggc aacagctacagccctgccccgctggacctctgcaacgtggcgctctccagggagctgcag gggatggtggaggtcatagctgagaactatcacaacatctgggccaagaagaagaagctg gagctggagagcaaaggtggtggcagtcaccctcttttggttccatatgacaccttgact gccaaggagaagtctagggaccgagagaaggcacaggacctgtttaaattcctccaagtg aatggcatcgtggtgtctagaggtatgaaggatatggagctggatgcctcctccatggaa aagaggtttgcctataaatttttgaagaagatcctgaaatatgttgattctgctcaagag tttattgcccatttggaagccattgtcatcagtgggaaaactgaaaggtctccccatgac caggagatcaaattctttgccaaagtgctcctcccgctggttgaccaatacttcaccaat caccgcctctacttcctgtcgtccccgctgaagccccttagcagcagtgggtatgcctcc cataaggagaaagaaatggtggccagcctgttctgcaaacttgccgctcttgttcggcac aggatttccctcttcgggagcgattctactacaatggtgagctgccttcacatcttagct cagacactggacacaaggactgtcatgaagtcaggctcagagctggtgaaggccgggtta cgcgcattctttgaaaatgctgcggaagacttagagaagacttcagaaaacctgaagctc gggaagttcacccattccagaacgcagattaaaggcgtctctcagaacattaactacacc acggcggcgctgctccccatcctcacgtccatctttgagcatgtggctcagcaccagttc ggggtggatttactcttgggtgacgtgcagatttcatgctaccacatattatgcagcctc tactcccttggaacaggaaagaacatctatgtggaaagacaacgtcctgcccttggagaa tgcctggcttccctggcagctgccattccagtggcattcctggagcccacccttaaccgc tacaatccgctctccgtcttcaacaccaaaacccccagggagagatctattctgggggtg ccagacacagtggaagagatgtgtcctgacatccccccgctggaacgcctcatgaaggaa atccaccacctagccgagtccggagcccggtacacagagatgccccatgtcatcgaggtg atcctgcccatgctctgcaactacctgtcctactggtgggagcaggggcctgagcacctg ccccccagcacagggccctggtgcaccaaagtcacctcagaacacctcagcgtcatcctg ggcaacatcctgaaaatcatcaacaacaacctgggcatcgatgaggcctcctggatgaag cgcatcgcagtgtacgcccagccaatcatcagcaaagccaggcctgacctgctcagaagc cacttcatcccaactctggagaagctgaagaaaaaggctgtcaagactgtgcaggaggaa gagcagctgaaagctgacagcaaaggggacacacaggaggcggagctcctcatcctggat gagttcgcagtcctctgcagagacctctacgccttctaccccatgctcatccgctatgtg gacaacaacagatccaactggctcaaaagccccgatgctgattctgaccagctcttccgc atggtggcagaggtcttcatcctgtggtgcaagtctcacaacttcaagagggaagagcaa aattttgtgattcagaatgaaattaataatttggcatttttaactggagacagcaaaagc aagatgtcaaaagccatgcaagtaaagtccggagggcaggaccaggagcggaagaagacg aagcggaggggagacttgtattccatccagacctccctcatcgtggctgcgctcaagaag atgttgcctattggtctgaatatgtgcaccccgggcgaccaggagctgatctccctcgcg aaatcacgatacagctgcagggacaccgatgaagaggtgaaggaacacctgcggaataac ttgcacttgcaggaaaagtctgatgatccggctgtaaagtggcaactgaatctctacaag gatgttttgaagagtgaagaaccttccaatccagaaaagaccgtggagcgtgtgcagaga atttcagcagctgtcttccacctggagcaggtggagcagcctttgaggtccaagaaggca gtctggcacaagctgttgtctaagcagcggaaacgggcagtggtggcctgtttcaggatg gcccctctctacaacctgcccaggcaccgctctattaacctcttcctccatggctatcag agattttggatagaaacagaggagtattcatttgaagagagactagtacaggatttggct aaatcccccagggcggaagaggaggaggaggcggaggcagaaaagcagccagacccactg caccagatcgttctccatttcagccgcaatgctctcacggagaggagcaaattggaagat gaccctttgtacacctcctattccagcatgatggccaagagttgtcaggatggggaggat gaagaagaggaggaagacaaggaaaaaacatttgaggaaaaagaaatggaaaagcagaaa accctctatcagcaagcgcggctgcatgagcgtggggctgccgagatggtccttcagatg ataagcgccagcaaaggtgagcggagccccatggtggttgagactctgaagctggggatt gccattctgaatggaggcaacgccggcgtgcaacagaaaatgttagattacctaaaggag aaaaaggatgctggattctttcaaagcctttctggtcttatgcagtcttgcagtgtcctt gatttgaatgcatttgagaggcagaataaagctgaaggcctggggatggttactgaggaa ggaacactcattgttcgtgagcgtggtgaaaaagtactccagaatgacgagttcacacga gatctctttagattcctacagttactttgtgaaggacataacaatgactttcagaacttc ctgcggactcagatgggtaacaccaccaccgtgaacatcatcatcagcactgtggactac cttctgcgtcttcaggaatcaatcagtgatttctactggtactattcagggaaggacatc atcgatgaatctggacagcacaatttttccaaagctctagtggtcacaaagcagattttc aattctcttacagaatacatccagggcccttgcattgggaaccagcagagcctggctcac agcaggctgtgggatgcggtggtcggcttcctccatgtatttgctaacatgcagatgaaa ctctctcaggattccagtcagatcgagctgttgaaggaactcttggatctccttcaggac atggtggtgatgcttctgtccctcctggaagggaatgtggtaaatggaactattggcaag cagatggttgacacactggtagagtcatctaccaatgtagaaatgatcctgaaattcttt gacatgttcttgaaacttaaagacttaaccagctcagacaccttcaaagaatatgaccca gatggtaaagggattatctccaaaaaagaattccagaaggccatggaagggcaaaaacag tacacacagtcagagattgactttctcctttcttgtgcagaagctgatgagaatgacatg tttaattacattgattttgtcgaccggttccatgagccggccaaggatatagggtttaat gtggcagtgttattgacaaatctctcggagcatatgccaaatgattctcgccttaagtgt ctgttggacccagcagaaagtgtgctaaactacttcgaaccatacctaggacgcattgag attatgggtggtgccaagaaaattgagcgtgtttattttgagatcagtgaatccagtcga actcaatgggaaaagccccaagtgaaggaatctaagcgacagtttatcttcgatgttgtc aatgaaggtggggaacaggaaaagatggaactgtttgtgaacttctgtgaggataccatc tttgaaatgcagttagcatctcagatttctgaatccgactcaaatgacagagcagaagag gaggaggaggaagatgaagactcttcttacacattagagattgagggggaagaagaggat gacaaatcctttgagtctgtctctgcatttgccatggcctgtgcctcagtgaagagaaat gttgccaactttctaaagagggtaactctgaagaacctcaggaagcaatacaggaaggtg aaaaagatgactgtgaaggagctggtaaaggtgttcttctcattcttctggatgttgttc gtggggctgttccggttgttcttcaccatcttggggggaatctttcagatcctctggaac acagtgtttggagggggcctggtagaaggggcaaagaacatcagggtgatcaagatcctg ggggacatgcctgatccaacccagtttggtatccatgatgatgttttggaagctgagagg gcagaagtgaccgagacgggtatcaccacggaactagtgcactttttaaagggtgagaaa ggagatgcggatattatgtcagatctttttggattccactccaagaaagaaggtggctca aagcatgggccagaagtgggtttgggtgacctctctgagattattggcaaggatgaaccc cctacactagagagtactgtacggaagaaaaggaaagtacaggcagcagagatgaaagca gcacatgactcagaaggaaaagtggaacccgagaaggcagacatggaagatggggagaag gaggagacagctggagaacaagccaaggtcctgtgggcagaggcgacaaaaaagaagaag cggcggcgtggtcagaaagtcgagaagcctgaagccttcatggctaatttcttcaaaggg ctggaaatctatcagaccaagttactgcattacctggccaggaatttctacaacctgagg ttcctcgctctgtttgtagccttcgctatcaacttcatcctgctcttttacaaggtcact gaagagcctttagaagaggaggcagaggatgtggtgaacctgtggcattccttcagtgac gacgaggaggaggaagcgatggtgttctttgtccttcaggagagcactgggtacatggcc ccagcgttgcgggcgctggccgttatccacaccatcatctctttagtctgcgtggtgggc tattactgcctcaaggtccctttggtggtattcaaaagagaaaaggaaattgccaggaag ctggagtttgatggtctgtatatcaccgaacagccatctgaagatgacatcaaggggcaa tgggaccgcttggtaatcaacacaccatctttccctaataactactgggacaagtttgta aagagaaaggtgataaacaagtatggtgatctctacggagcggaacgcattgctgaactc ctgggtttggacaaaaatgccctggactttagccccgtagaagagaccaaagcagaggcg gcctcgctggtgtcatggctaagttccattgacatgaagtaccatatctggaagctggga gttgtttttactgacaattcctttctctacctggcctggtacacaaccatgtccatcctg ggccactacaacaacttcttcttcgctgctcacctgctggatatagccatgggcttcaag acactgaggaccatcctatcgtctgtaactcataacggcaaacagctggttctgaccgtg ggcctcctggccgtggtggtttacctctacaccgtggtggctttcaacttcttccgcaag ttctacaacaagagtgaggacgacgacgagcccgacatgaagtgtgacgacatgatgacg tgttacctgttccacatgtacgtgggagtgagagctggaggtggcattggcgatgagatt gaagaccccgctggggatccttacgaaatgtaccgcattgtcttcgacatcacctttttc ttctttgtcatcgtcatcttgctggccatcatccaaggtcttattattgacgcttttgga gagttgagagaccagcaggaacaagtacgagaagatatggagactaaatgtttcatctgt gggattggcaatgactactttgacacaacccctcatggttttgaaacacacacattacaa gagcacaacttagccaactacttgttcttcctgatgtatttgattaacaaagatgaaaca gagcacacgggtcaggaatcgtatgtctggaagatgtaccaagaaaggtgttgggatttc ttcccagctggtgactgctttcggaaacaatatgaggatcagcttggataa

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