Mustela nigripes (black-footed ferret): 132004145
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Entry
132004145 CDS
T09425
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp03440
Homologous recombination
mnp03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
132004145 (TOP3A)
03460 Fanconi anemia pathway
132004145 (TOP3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mnp03032
]
132004145 (TOP3A)
03400 DNA repair and recombination proteins [BR:
mnp03400
]
132004145 (TOP3A)
Enzymes [BR:
mnp01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
132004145 (TOP3A)
DNA replication proteins [BR:
mnp03032
]
Eukaryotic type
DNA Topoisomerases
132004145 (TOP3A)
DNA repair and recombination proteins [BR:
mnp03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
132004145 (TOP3A)
FA (Fanconi anemia) pathway
132004145 (TOP3A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Zn_ribbon_Top1
Toprim
Zn_ribbon_GRF_2
zf-C2H2_10
Zn_ribbon_recom
Motif
Other DBs
NCBI-GeneID:
132004145
NCBI-ProteinID:
XP_059236252
LinkDB
All DBs
Position
16:47712214..47739891
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AA seq
994 aa
AA seq
DB search
MIFPVARCALRWLERPGARTLSRAAMAVAFRGVRKILCVAEKNDAAKGIADLLSNGRMRR
REGFSKFNKIYEFDYHLYGQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK
YCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCRAVKPNLPVLRARFSE
ITPRAVRAACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS
YGSCQFPTLGFVVERFKAIQAFVPEIFHKIKVTHDHKDGVVEFNWKRHRLFNHTACLVLY
QLCMEDPRATVVEVRSKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
SYPRTETNIFPKDLNLTVLVEQQIPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPT
KYTGSLQGDEQRLYEFIVRHFLACCSHDAQGQETTVEIDIAQERFVAHGLVILARNYLDV
YPYDHWSDKTLPVYERGARFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAE
HIETIKARMYVGLTADKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKK
DKWVVLRQQVQKYKQVFIEALAKAKKLDEALAQYFGEGAEVAQEEAIYPSMPEPIKKCPQ
CNKDMVLKTKKNGGFYLSCTGFPECRSAVWFPDSVLEASRDASVCPVCQPHPVYRLKLKF
KRGSLPPTMPLEFVGCIGGCDETLREILDLRFSRGPPRASQSASQPSNYLQASQSLNRMD
STPWMPPPPATATGGSNSVTCNCGQEAVLLTVRKEGPNQGRQFYKCNGGGCSFFLWANSS
PPEAGGPPSSASRPPGGSMGRPPATGDRRGRSGRPGDDSGGGGGGRSMSCLCSQPAVTRT
VQKDGPNKGRQFHTCAKPREQQCGFFQWVDENMAPGTFRALSWPGSRGGTQGPEARSKRA
RAGSTDSGSMPKKPRKCSLCHQPGHTRPFCPQNR
NT seq
2985 nt
NT seq
+upstream
nt +downstream
nt
atgatcttcccggtcgcccgttgcgcgctccgctggctggaacggccgggagcccggacc
ttgtcccgcgctgccatggcggtggccttccgaggcgtgcggaaaattctgtgtgtggcc
gagaagaacgacgcggccaaggggatagccgacctgctgtccaacggtcgcatgaggcgg
agggaaggattttcaaaattcaacaagatctatgaatttgattatcatctatatggccag
aatgttaccatgataatgacttcagtttctggacatttgctggctcatgatttccagatg
cagtttcgcaaatggcagagctgcaatcccctggtcctctttgaagcagaaattgaaaag
tattgcccggagaattttgtagacatcaagaaaactctggaacgagagactcggcagtgc
caggccctggtgatctggaccgactgtgatagagaaggtgaaaatatcgggtttgaaatt
atccacgtgtgcagggctgtgaagcccaatctgccggtactgagagcccgtttctcagag
atcaccccccgagctgtccgggcggcctgtgaaaacctgacggagcccgatcagagagtg
agcgatgccgtggacgtgaggcaggagctggacctgagaatcggagccgccttcactagg
ttccagaccctgaggcttcagaggatttttcctgaggtgttggcagagcagctaatcagt
tacggcagctgccagttcccaaccctggggttcgtggtggagagattcaaagccattcag
gcttttgtgccggaaatcttccacaaaattaaagtaactcatgaccataaagatggagtc
gtagaattcaactggaaaaggcatcgtctctttaaccacacggcttgtcttgtcctctac
cagctgtgcatggaggatcccagggcaaccgtggtggaggtcaggtctaaggcaaagagc
aagtggaggcctcaagctttggacactgtggaacttgagaagctggcttctcgaaagttg
agaataaatgctaaagaaaccatgaggattgccgaaaagctctacactcaagggtacatc
agctatcctcgcactgaaacaaacattttccccaaagacttgaacctgactgtgctggtg
gagcagcagatcccagatccacgctggggcgcctttgcccagagcattctggaacggggt
ggccccactccacgcaatggaaacaagtctgatcaagctcaccctcccatccaccccacc
aaatacaccggcagcctgcagggagacgagcagcgactgtatgagttcatagtgcgccat
ttcctggcctgctgctcccacgatgctcagggccaggagaccactgtggagatcgacatc
gcacaggaacgcttcgtggctcatggcctcgtgattttggcccgaaactatctggacgtg
tacccgtatgaccactggagtgacaagaccctccctgtctacgagagaggcgcccgcttc
cagcccagcactgtggagatggtggacggggagaccagcccaccccagctgctcaccgaa
gctgacctcatcgccctcatggagaagcacggcattgggactgatgccactcacgcggag
cacatcgagacaatcaaggcccggatgtacgttgggctcacggcggacaagcggtttctc
ccggggcatctgggcatggggctcgtggaaggttatgactccatgggctatgagatgtcc
aagcctgacctccgggccgagctggaagctgacctgaagctgatctgtgaaggcaagaag
gacaagtgggtggttctaaggcagcaagtccagaaatacaagcaggttttcattgaagcg
ctggccaaagctaagaaattggatgaagcgttagcccagtactttggggaaggggccgag
gtggcccaggaggaagccatctacccaagcatgccggagcccatcaagaagtgtccacag
tgcaacaaggacatggtcctcaagaccaagaagaatggcgggttctacctcagctgcacg
ggcttcccagaatgccggtcagccgtgtggttccctgactctgtgctggaggccagcagg
gacgcgagcgtgtgtccagtgtgtcagccgcacccggtttacaggttgaagctgaagttc
aaacgcggcagccttcccccaaccatgcccctggagtttgtcggctgcattggcggatgc
gacgagacgctgcgggagatcttggacctgaggttctcacggggccctcccagagcttcc
cagtcagccagccagccctcgaactacctgcaggctagccagtccctaaacagaatggac
agcaccccctggatgccaccaccacctgctactgccacggggggcagcaactcggtgacc
tgcaactgcggccaggaggccgtcctgctcacagtgcgaaaggagggccccaaccagggc
cgccagttctataagtgcaatggtggcggctgcagcttcttcctatgggccaacagcagc
cccccagaagctggggggcctccctcctccgcctcaagaccccctggtggctcaatgggc
cgcccgcctgccacaggggaccgccggggcaggtctggccgacccggggatgacagtggt
ggtggcggcggcgggaggagcatgtcctgcctatgcagccagcctgccgtcacccggact
gtgcagaaggacggccccaacaagggccgccagttccacacgtgcgccaagcccagggag
cagcagtgcggcttctttcagtgggtggacgagaacatggctccagggactttcagagcc
ctgagctggccgggaagcagaggaggaacccaggggccagaggccagaagcaaaagagcc
cgggccggttccacagactcagggtccatgcccaagaaaccccggaaatgcagcctttgc
caccagcctggacacacccgtcccttctgtccccagaacagatga
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